Research Topics
Genomes and GenesSpecies | S DarveshSummaryAffiliation: Dalhousie University Country: Canada Publications
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Detail Information
Publications
Distribution of butyrylcholinesterase in the human amygdala and hippocampal formationS Darvesh
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
J Comp Neurol 393:374-90. 1998..The distinct distribution of BuChE suggests that it may have specific functions including coregulation of cholinergic and noncholinergic neurotransmission in human amygdala and hippocampal formation...
Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activityS Darvesh
Department of Anatomy, Dalhousie University, Halifax, Nova Scotia, Canada
J Auton Nerv Syst 71:75-84. 1998....
Butyrylcholinesterase-Mediated enhancement of the enzymatic activity of trypsinS Darvesh
Department of Medicine, Halifax, Nova Scotia, Canada
Cell Mol Neurobiol 21:285-96. 2001..6. We suggest that, in addition to its esterase activity, BuChE may assume a regulatory role by interacting with other proteins...
Butyrylcholinesterase and cognitive functionS Darvesh
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
Int Psychogeriatr 13:461-4. 2001..We suggest that, because neurons expressing BuChE may be involved in cognition, there is merit to further evaluation of selective BuChE inhibitors in treating cognitive dysfunction...
Biochemical and histochemical comparison of cholinesterases in normal and Alzheimer brain tissuesS Darvesh
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
Curr Alzheimer Res 7:386-400. 2010....
Retrospective diagnosis of dementia using an informant interview based on the Brief Cognitive Rating ScaleK Rockwood
Department of Medicine, Dalhousie University, Halifax, Canada
Int Psychogeriatr 10:53-60. 1998..The RetroBCRS used by an expert physician with a reliable informant is a valid method of detecting dementia and determining whether AD was present...
Spectrum of disease in vascular cognitive impairmentK Rockwood
Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
Neuroepidemiology 18:248-54. 1999..To better understand and treat ischaemic causes of cognitive impairment, the concept of VaD should be expanded to include patients who do not meet traditional dementia criteria...
Butyrylcholinesterase and the cholinergic systemG A Reid
Department of Medical Neuroscience Dalhousie University, Halifax, Nova Scotia, Canada
Neuroscience 234:53-68. 2013..These observations provide further neuroanatomical evidence of a role for BuChE in the regulation of acetylcholine levels in the CNS...
The behavioural neurology assessmentS Darvesh
Department Neurology and Geriatric Medicine, Dalhousie University, Halifax, NS, Canada
Can J Neurol Sci 32:167-77. 2005..93 versus .79). Specificity was equivalent to the MMSE (.93 versus .97). CONCLUSIONS: Positive predictive values of the BNA and MMSE are equivalent but the BNA provides superior negative predictive value...
