Gilles R Dagenais

Summary

Country: Canada

Publications

  1. ncbi request reprint What induces the warm-up ischemia/angina phenomenon: exercise or myocardial ischemia?
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, 2725 Chemin Ste Foy, Ste Foy, Quebec, Canada G1V 4G5
    Circulation 107:1858-63. 2003
  2. ncbi request reprint Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trials
    Gilles R Dagenais
    The Laval University Heart and Lung Institute, Laval Hospital, Quebec, Canada G1V 4G5
    Lancet 368:581-8. 2006
  3. pmc Challenges for the Canadian Cardiovascular Society in the 1990s
    Gilles R Dagenais
    Institut Universitaire de Cardiologie et Pneumologie, Hopital Laval, Quebec, Canada
    Can J Cardiol 23:913-4. 2007
  4. doi request reprint Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial
    G R Dagenais
    Laval University Heart and Lung Institute, 2725 Chemin Ste Foy, Quebec, Quebec City, Canada
    Diabetes Care 31:1007-14. 2008
  5. pmc Comparison of prognosis for men with type 2 diabetes mellitus and men with cardiovascular disease
    Gilles R Dagenais
    Institut Universitaire de Cardiologie et Pneumologie, Montreal, Que
    CMAJ 180:40-7. 2009
  6. ncbi request reprint Impact of cigarette smoking in high-risk patients participating in a clinical trial. A substudy from the Heart Outcomes Prevention Evaluation (HOPE) trial
    Gilles R Dagenais
    Laval University Heart and Lung Institute, Ste Foy, Quebec G1V 4G5, Canada
    Eur J Cardiovasc Prev Rehabil 12:75-81. 2005
  7. ncbi request reprint Fluctuating inflammatory markers in patients with stable ischemic heart disease
    Peter Bogaty
    Quebec Heart Institute, Laval Hospital, Laval University, Quebec City, Quebec, Canada
    Arch Intern Med 165:221-6. 2005
  8. ncbi request reprint Job strain and risk of acute recurrent coronary heart disease events
    Corine Aboa-Eboulé
    Unité de recherche en santé des populations, Universite Laval, Quebec, Canada
    JAMA 298:1652-60. 2007
  9. ncbi request reprint Inflammatory markers and long-term risk of ischemic heart disease in men A 13-year follow-up of the Quebec Cardiovascular Study
    Annie C St-Pierre
    Department of Nutrition, Institute on Nutraceuticals and Functional Foods, Laval University, 2440 Hochelaga Blvd, Ste Foy, Que, Canada G1K 7P4
    Atherosclerosis 182:315-21. 2005
  10. doi request reprint Effort-reward imbalance at work and recurrent coronary heart disease events: a 4-year prospective study of post-myocardial infarction patients
    Corine Aboa-Eboulé
    Centre de recherche du CHA, Unité de recherche en santé des populations, Quebec City, Canada
    Psychosom Med 73:436-47. 2011

Detail Information

Publications43

  1. ncbi request reprint What induces the warm-up ischemia/angina phenomenon: exercise or myocardial ischemia?
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, 2725 Chemin Ste Foy, Ste Foy, Quebec, Canada G1V 4G5
    Circulation 107:1858-63. 2003
    ....
  2. ncbi request reprint Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trials
    Gilles R Dagenais
    The Laval University Heart and Lung Institute, Laval Hospital, Quebec, Canada G1V 4G5
    Lancet 368:581-8. 2006
    ....
  3. pmc Challenges for the Canadian Cardiovascular Society in the 1990s
    Gilles R Dagenais
    Institut Universitaire de Cardiologie et Pneumologie, Hopital Laval, Quebec, Canada
    Can J Cardiol 23:913-4. 2007
  4. doi request reprint Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial
    G R Dagenais
    Laval University Heart and Lung Institute, 2725 Chemin Ste Foy, Quebec, Quebec City, Canada
    Diabetes Care 31:1007-14. 2008
    ..We determined the effects of ramipril and rosiglitazone on combined and individual CVD and renal outcomes in people with IGT and/or IFG in the Diabetes REduction Assessment With ramipril and rosiglitazone Medication (DREAM) trial...
  5. pmc Comparison of prognosis for men with type 2 diabetes mellitus and men with cardiovascular disease
    Gilles R Dagenais
    Institut Universitaire de Cardiologie et Pneumologie, Montreal, Que
    CMAJ 180:40-7. 2009
    ..We compared cardiovascular mortality between incident cases of diabetes and cardiovascular disease...
  6. ncbi request reprint Impact of cigarette smoking in high-risk patients participating in a clinical trial. A substudy from the Heart Outcomes Prevention Evaluation (HOPE) trial
    Gilles R Dagenais
    Laval University Heart and Lung Institute, Ste Foy, Quebec G1V 4G5, Canada
    Eur J Cardiovasc Prev Rehabil 12:75-81. 2005
    ..In recent large cardiovascular trials done in stable patients, 14-31% of the participants were smokers; the consequences of smoking in these trials using medications known to reduce cardiovascular events, have not been assessed...
  7. ncbi request reprint Fluctuating inflammatory markers in patients with stable ischemic heart disease
    Peter Bogaty
    Quebec Heart Institute, Laval Hospital, Laval University, Quebec City, Quebec, Canada
    Arch Intern Med 165:221-6. 2005
    ..However, little is known about how inflammatory markers fluctuate over time in patients with stable ischemic heart disease...
  8. ncbi request reprint Job strain and risk of acute recurrent coronary heart disease events
    Corine Aboa-Eboulé
    Unité de recherche en santé des populations, Universite Laval, Quebec, Canada
    JAMA 298:1652-60. 2007
    ..There is evidence that job strain increases the risk of a first coronary heart disease (CHD) event. However, little is known about its association with the risk of recurrent CHD events after a first myocardial infarction (MI)...
  9. ncbi request reprint Inflammatory markers and long-term risk of ischemic heart disease in men A 13-year follow-up of the Quebec Cardiovascular Study
    Annie C St-Pierre
    Department of Nutrition, Institute on Nutraceuticals and Functional Foods, Laval University, 2440 Hochelaga Blvd, Ste Foy, Que, Canada G1K 7P4
    Atherosclerosis 182:315-21. 2005
    ..An inflammation score based on high plasma IL-6 and fibrinogen levels used in combination with traditional risk factors may improve our ability to adequately identify high risk individuals...
  10. doi request reprint Effort-reward imbalance at work and recurrent coronary heart disease events: a 4-year prospective study of post-myocardial infarction patients
    Corine Aboa-Eboulé
    Centre de recherche du CHA, Unité de recherche en santé des populations, Quebec City, Canada
    Psychosom Med 73:436-47. 2011
    ..The objective of this study was to determine whether ERI at work and its components (effort and reward) increase the risk of recurrent CHD in post-myocardial infarction (post-MI) workers...
  11. doi request reprint Effects of exogenous metabolic substrate modulation on exercise-induced myocardial ischemia
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, Laval University, Quebec City, Quebec, Canada
    Am Heart J 156:790-6. 2008
    ..The aim of the study is to compare the impact of intravenous glucose versus lipid versus saline on exercise-induced myocardial ischemia in patients with stable angina...
  12. pmc Insulin resistance syndrome, body mass index and the risk of ischemic heart disease
    Annie C St-Pierre
    Institute on Nutraceuticals and Functional Foods, Lipid Research Centre, Ste Foy, Que
    CMAJ 172:1301-5. 2005
    ....
  13. doi request reprint Effort-reward imbalance at work and psychological distress: a validation study of post-myocardial infarction patients
    Corine Aboa-Eboulé
    Unité de recherche en santé des populations, Centre Hospitalier Universitaire de Quebec, Quebec City, Canada
    Psychosom Med 73:448-55. 2011
    ....
  14. ncbi request reprint Low-density lipoprotein subfractions and the long-term risk of ischemic heart disease in men: 13-year follow-up data from the Québec Cardiovascular Study
    Annie C St-Pierre
    Institute on Nutraceuticals and Fonctionnal Foods, Laval University, Quebec, Canada
    Arterioscler Thromb Vasc Biol 25:553-9. 2005
    ..The objective of the present study was to investigate the association between large and small low-density lipoprotein (LDL) and long-term ischemic heart disease (IHD) risk in men of the Quebec Cardiovascular Study...
  15. doi request reprint Clinical utility of C-reactive protein measured at admission, hospital discharge, and 1 month later to predict outcome in patients with acute coronary disease. The RISCA (recurrence and inflammation in the acute coronary syndromes) study
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, Laval University, Quebec City, Quebec, Canada
    J Am Coll Cardiol 51:2339-46. 2008
    ....
  16. ncbi request reprint Concordance/discordance between plasma apolipoprotein B levels and the cholesterol indexes of atherosclerotic risk
    Allan D Sniderman
    Mike Rosenbloom Laboratory for Cardiovascular Research, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Cardiol 91:1173-7. 2003
    ....
  17. ncbi request reprint Effect of plasma C-reactive protein levels in modulating the risk of coronary heart disease associated with small, dense, low-density lipoproteins in men (The Quebec Cardiovascular Study)
    Annie C St-Pierre
    Institute on Nutraceuticals and Fonctionnal Foods, Laval University, Ste Foy, Quebec, Canada
    Am J Cardiol 91:555-8. 2003
    ..6 vs 3.0). Thus, increased plasma CRP levels further elevate the risk of CHD associated with having small, dense LDL particles...
  18. ncbi request reprint Can prolonged exercise-induced myocardial ischaemia be innocuous?
    Martin Noel
    Quebec Heart Institute, Laval Hospital, Laval University, 2725 Chemin Ste Foy, Ste Foy, Quebec, Canada G1V 4G5
    Eur Heart J 28:1559-65. 2007
    ..To evaluate the innocuousness of intense and prolonged exercise training above the threshold for myocardial ischaemia (1 mm ST-segment depression)...
  19. ncbi request reprint Prognostic impact of body weight and abdominal obesity in women and men with cardiovascular disease
    Gilles R Dagenais
    Department of Cardiology, Laval University Heart and Lung Institute, Ste Foy, Quebec, Canada
    Am Heart J 149:54-60. 2005
    ..Increased body mass index (BMI) and abdominal adiposity increase the risk of cardiovascular disease (CVD) in persons free of these diseases, but their independent prognostic impact in persons with CVD has not been well defined...
  20. ncbi request reprint Association of fibrinogen and lipoprotein(a) as a coronary heart disease risk factor in men (The Quebec Cardiovascular Study)
    Bernard Cantin
    Quebec Heart Institute, Ste Foy, Quebec, Canada
    Am J Cardiol 89:662-6. 2002
    ..5; 95% CI 1.2 to 5.1; p = 0.0132). In this population, high fibrinogen levels associated with high Lp(a) levels significantly increased the risk of CHD...
  21. ncbi request reprint Apolipoprotein-B, low-density lipoprotein cholesterol, and the long-term risk of coronary heart disease in men
    Annie C St-Pierre
    Institute on Nutraceuticals and Functional Foods, Ste Foy, Quebec, Canada
    Am J Cardiol 97:997-1001. 2006
    ..04). In conclusion, plasma apo-B levels modulated the risk of CHD associated with LDL cholesterol over a 13-year follow-up...
  22. ncbi request reprint Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity
    Gilles R Dagenais
    Laval University Heart and Lung Institute, Ste Foy, Quebec, Canada
    Can J Cardiol 19:1387-91. 2003
    ..Such a relationship has not been assessed in patients with ICVD who may have a different occurrence due to their disease and medications...
  23. pmc Effects of job strain on blood pressure: a prospective study of male and female white-collar workers
    Chantal Guimont
    Unité de recherche en santé des populations, Quebec City, Quebec, Canada
    Am J Public Health 96:1436-43. 2006
    ..We evaluated whether cumulative exposure to job strain increases blood pressure...
  24. ncbi request reprint Impact of prolonged cyclooxygenase-2 inhibition on inflammatory markers and endothelial function in patients with ischemic heart disease and raised C-reactive protein: a randomized placebo-controlled study
    Peter Bogaty
    Quebec Heart Institute Laval Hospital, Laval University, 2725 Chemin Ste Foy, Quebec City, Quebec, Canada G1V 4G5
    Circulation 110:934-9. 2004
    ..We investigated the effect of prolonged COX-2 inhibition on inflammatory profile and endothelial function in patients with ischemic heart disease and high serum C-reactive protein (CRP) values...
  25. pmc Prognostic impact of the presence and absence of angina on mortality and cardiovascular outcomes in patients with type 2 diabetes and stable coronary artery disease: results from the BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes)
    Gilles R Dagenais
    Quebec Heart and Lung University Institute, Quebec City, Quebec, Canada
    J Am Coll Cardiol 61:702-11. 2013
    ....
  26. ncbi request reprint Different thresholds of myocardial ischemia in ramp and standard bruce protocol exercise tests in patients with positive exercise stress tests and angiographically demonstrated coronary arterial narrowing
    Martin Noel
    Quebec Heart Institute Laval Hospital, Laval Sainte University Foy, Quebec, Canada
    Am J Cardiol 99:921-4. 2007
    ..This effect is unexplained by energy expenditure (VO2) or myocardial work (RPP) and is consistent with a "warm-up" ischemic mechanism...
  27. ncbi request reprint Effect of atorvastatin on exercise-induced myocardial ischemia in patients with stable angina pectoris
    Peter Bogaty
    Quebec Heart Institute, Laval Hospital, Ste Foy, Quebec, Canada
    Am J Cardiol 92:1192-5. 2003
    ..Endothelial function improved progressively and C-reactive protein, P-selectin, and tissue plasminogen activator inhibitor levels decreased, but there was no decrease in exercise electrocardiographic ischemia...
  28. ncbi request reprint Impact of ramipril on the circadian periodicity of acute myocardial infarction
    Gilles R Dagenais
    University Heart and Lung Institute, Laval Hospital, and the Department of Medicine, Laval University, Quebec, Quebec, Canada
    Am J Cardiol 98:758-60. 2006
    ..In conclusion, inhibiting angiotensin-converting enzyme decreased AMI over a 24-hour period, but this enzyme does not seem to play a major role in the circadian periodicity of this acute event...
  29. pmc The Quebec Heart Institute: 50 years of excellence in cardiology
    Gilles R Dagenais
    Quebec Heart Institute, Laval Hospital, Sainte Foy, Quebec
    Can J Cardiol 23:5B-8B. 2007
    ..The first 50 years of the Quebec Heart Institute are depicted in this overview, which will also introduce this special supplement to The Canadian Journal of Cardiology...
  30. doi request reprint Effects of optimal medical treatment with or without coronary revascularization on angina and subsequent revascularizations in patients with type 2 diabetes mellitus and stable ischemic heart disease
    Gilles R Dagenais
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, QC, Canada
    Circulation 123:1492-500. 2011
    ..In the same population, we tested whether the REV strategy was superior to the MED strategy in preventing worsening and new angina and subsequent coronary revascularizations...
  31. pmc Time variability of C-reactive protein: implications for clinical risk stratification
    Peter Bogaty
    Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada
    PLoS ONE 8:e60759. 2013
    ..We sought to determine the stability of serial CRP measurements in stable subjects with distinct CAD manifestations and a group without CAD while carefully controlling for known confounders...
  32. doi request reprint Comparison of plaque sealing with paclitaxel-eluting stents versus medical therapy for the treatment of moderate nonsignificant saphenous vein graft lesions: the moderate vein graft lesion stenting with the taxus stent and intravascular ultrasound (VELETI
    Josep Rodes-Cabau
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, 2725, Chemin Sainte Foy, Quebec, Canada
    Circulation 120:1978-86. 2009
    ..We determined the effects of sealing moderate nonsignificant SVG lesions with paclitaxel-eluting stents (PES) on the prevention of SVG atherosclerosis progression...
  33. ncbi request reprint A multivariate model for predicting mortality in patients with heart failure and systolic dysfunction
    James M Brophy
    Division of Cardiology and Clinical Epidemiology, McGill University Health Center, Montreal, Quebec, Canada
    Am J Med 116:300-4. 2004
    ..Heart failure is a leading cause of morbidity and mortality, but there are no reliable models based on readily available clinical variables to predict outcomes in patients taking angiotensin-converting enzyme (ACE) inhibitors...
  34. ncbi request reprint Psychologic distress in postmyocardial infarction patients who have returned to work
    Chantal Brisson
    Unité de recherche en santé des populations, Centre Hospitalier Universitaire de Quebec, Hôpital Saint Sacrement, 1050 Chemin Sainte Foy, Quebec, Quebec, Canada G1S 4L8
    Psychosom Med 67:59-63. 2005
    ..To assess the prevalence of psychologic distress in women and men returning to work after a myocardial infarction (MI) and to compare this prevalence with the prevalence observed among men and women of the general working population...
  35. ncbi request reprint Revisiting the Canadian Cardiovascular Society grading of stable angina pectoris after a quarter of a century of use
    Gilles R Dagenais
    Departement de Medecine, Université Laval and Institut universitaire de cardiologie et de pneumologie, Ste Foy, Canada
    Can J Cardiol 18:941-4. 2002
  36. ncbi request reprint Plasma free fatty acid levels and the risk of ischemic heart disease in men: prospective results from the Québec Cardiovascular Study
    Matteo Pirro
    Department of Food Science and Nutrition, Lipid Research Center, R 9600 CHUL Research Center, 2705 Laurier Boulevard, Ste Foy, G1V 4G2, Quebec, Canada
    Atherosclerosis 160:377-84. 2002
    ..However, a single fasting measurement of plasma FFA levels does not appear to improve our ability to predict IHD onset in men when information on other risk factors is considered...
  37. ncbi request reprint Can the Canadian Cardiovascular Society grading scale of angina influence clinical management and predict outcomes?
    Gilles R Dagenais
    Can J Cardiol 20:310. 2004
  38. ncbi request reprint Effects of vitamin E on cardiovascular outcomes in people with mild-to-moderate renal insufficiency: results of the HOPE study
    Johannes F E Mann
    Department of Nephrology and Hypertension, Schwabing General Hospital, Munich, Germany
    Kidney Int 65:1375-80. 2004
    ..There are no data for renal insufficiency before the stage of terminal renal failure. We evaluated effects of vitamin E supplementation on cardiovascular and renal outcomes in 993 people with a serum creatinine > or =1.4 to 2.3 mg/dL...
  39. ncbi request reprint Antecedent hypertension and the effect of captopril on the risk of adverse cardiovascular outcomes after acute myocardial infarction with left ventricular systolic dysfunction: Insights from the Survival and Ventricular Enlargement Trial
    Satish Kenchaiah
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am Heart J 148:356-64. 2004
    ..Hypertension is a well-established risk factor for myocardial infarction (MI), but its prognostic importance in survivors of an acute MI is less clear...
  40. ncbi request reprint Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial
    Eva Lonn
    Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario
    JAMA 293:1338-47. 2005
    ..Experimental and epidemiological data suggest that vitamin E supplementation may prevent cancer and cardiovascular events. Clinical trials have generally failed to confirm benefits, possibly due to their relatively short duration...
  41. ncbi request reprint Long-term effects of ramipril on cardiovascular events and on diabetes: results of the HOPE study extension
    Jackie Bosch
    Division of Cardiology, Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Circulation 112:1339-46. 2005
    ..6 years of follow-up and (2) observed in subgroups based on risk and ancillary treatments...
  42. ncbi request reprint Moderate alcohol consumption is more cardioprotective in men with the metabolic syndrome
    Iris Gigleux
    Institute on Nutraceuticals and Functional Foods Quebec City, QC, Canada
    J Nutr 136:3027-32. 2006
    ..22). These results confirm that moderate daily alcohol consumption has cardioprotective properties and suggest that the effects may be more important in subjects with a deteriorated risk profile, such as those with the metabolic syndrome...
  43. ncbi request reprint Does correction of the friedewald formula using lipoprotein(a) change our estimation of ischemic heart disease risk? The Quebec Cardiovascular Study
    Bernard Cantin
    Quebec Heart Institute, Laval University, Canada
    Atherosclerosis 163:261-7. 2002
    ..This study was undertaken to determine if correction of the Friedewald formula would result in a better evaluation of ischemic heart disease (IHD) risk...