Francois Robert

Summary

Affiliation: Clinical Research Institute of Montreal
Country: Canada

Publications

  1. pmc Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning
    Benoit Guillemette
    Centre de recherche sur les mécanismes du fonctionnement cellulaire, Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    PLoS Biol 3:e384. 2005
  2. pmc Global position and recruitment of HATs and HDACs in the yeast genome
    Francois Robert
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA 02142, USA
    Mol Cell 16:199-209. 2004
  3. pmc DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes
    Simon Drouin
    Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Canada
    PLoS Genet 6:e1001173. 2010
  4. pmc The euchromatic and heterochromatic landscapes are shaped by antagonizing effects of transcription on H2A.Z deposition
    Sara Hardy
    Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Canada
    PLoS Genet 5:e1000687. 2009
  5. pmc The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses
    Jeremie Poschmann
    Department of Medicine, Maisonneuve Rosemont Hospital, Research Center, University of Montreal, Montreal, Quebec, Canada
    PLoS ONE 6:e23159. 2011
  6. pmc Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance
    Sadri Znaidi
    Institute for Research in Immunology and Cancer, Universite de Montreal, Montreal, Quebec, Canada
    Eukaryot Cell 7:836-47. 2008
  7. doi request reprint Yeast RNase III triggers polyadenylation-independent transcription termination
    Ghada Ghazal
    RNA Group, Departement de Microbiologie et d Infectiologie, Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada
    Mol Cell 36:99-109. 2009
  8. pmc Histone H2A.Z is essential for estrogen receptor signaling
    Nicolas Gévry
    Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Genes Dev 23:1522-33. 2009
  9. ncbi request reprint Genome-wide replication-independent histone H3 exchange occurs predominantly at promoters and implicates H3 K56 acetylation and Asf1
    Anne Rufiange
    Centre de recherche en cancérologie de l Université Laval, L Hôtel Dieu de Québec CHUQ, Quebec, Canada
    Mol Cell 27:393-405. 2007
  10. pmc Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production
    Marc Larochelle
    Department of Medicine, Room H7 83, Royal Victoria Hospital, McGill University, 687 Pine Ave West, Montreal, Quebec, Canada
    Mol Cell Biol 26:6690-701. 2006

Collaborators

Detail Information

Publications13

  1. pmc Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning
    Benoit Guillemette
    Centre de recherche sur les mécanismes du fonctionnement cellulaire, Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    PLoS Biol 3:e384. 2005
    ..Our data suggest that the incorporation of H2A.Z into specific promoter-bound nucleosomes configures chromatin structure to poise genes for transcriptional activation. The relevance of these findings to higher eukaryotes is discussed...
  2. pmc Global position and recruitment of HATs and HDACs in the yeast genome
    Francois Robert
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA 02142, USA
    Mol Cell 16:199-209. 2004
    ....
  3. pmc DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes
    Simon Drouin
    Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Canada
    PLoS Genet 6:e1001173. 2010
    ..Taken together, our data support a model where Set2-dependent histone H3 methylation is required for the activation of Rpd3S following its recruitment to the RNA polymerase II C-terminal domain...
  4. pmc The euchromatic and heterochromatic landscapes are shaped by antagonizing effects of transcription on H2A.Z deposition
    Sara Hardy
    Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Canada
    PLoS Genet 5:e1000687. 2009
    ..These results show how chromatin structure and transcription can antagonize each other, therefore shaping chromatin and controlling gene expression...
  5. pmc The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses
    Jeremie Poschmann
    Department of Medicine, Maisonneuve Rosemont Hospital, Research Center, University of Montreal, Montreal, Quebec, Canada
    PLoS ONE 6:e23159. 2011
    ..We propose that Rrd1 is a novel transcription elongation factor that fine-tunes the transcriptional stress response of RNAPII...
  6. pmc Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance
    Sadri Znaidi
    Institute for Research in Immunology and Cancer, Universite de Montreal, Montreal, Quebec, Canada
    Eukaryot Cell 7:836-47. 2008
    ..They also suggest that Upc2p may contribute to azole resistance by regulating the expression of drug efflux pump-encoding genes in addition to ergosterol biosynthesis genes...
  7. doi request reprint Yeast RNase III triggers polyadenylation-independent transcription termination
    Ghada Ghazal
    RNA Group, Departement de Microbiologie et d Infectiologie, Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada
    Mol Cell 36:99-109. 2009
    ..These results support a model for transcription termination in which cotranscriptional cleavage by Rnt1p provides access for exoribonucleases in the absence of polyadenylation signals...
  8. pmc Histone H2A.Z is essential for estrogen receptor signaling
    Nicolas Gévry
    Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Genes Dev 23:1522-33. 2009
    ..Taken together, our results provide strong mechanistic insight into how H2A.Z regulates ERalpha-mediated gene expression and provide a novel link between H2A.Z-p400 and ERalpha-dependent gene regulation and enhancer function...
  9. ncbi request reprint Genome-wide replication-independent histone H3 exchange occurs predominantly at promoters and implicates H3 K56 acetylation and Asf1
    Anne Rufiange
    Centre de recherche en cancérologie de l Université Laval, L Hôtel Dieu de Québec CHUQ, Quebec, Canada
    Mol Cell 27:393-405. 2007
    ..Taken together, our data underline the dynamic nature of replication-independent nucleosome assembly/disassembly, specify a link to transcription, and implicate Asf1 and H3 K56 acetylation...
  10. pmc Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production
    Marc Larochelle
    Department of Medicine, Room H7 83, Royal Victoria Hospital, McGill University, 687 Pine Ave West, Montreal, Quebec, Canada
    Mol Cell Biol 26:6690-701. 2006
    ..These data suggest that Stb5 is a key player in the control of NADPH production for resistance to oxidative stress...
  11. pmc Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression
    Mathieu Blanchette
    McGill Centre for Bioinformatics, Montreal, Quebec, Canada, H3A 2B4
    Genome Res 16:656-68. 2006
    ..The set of predicted CRMs, which is made available as a public database called PReMod (http://genomequebec.mcgill.ca/PReMod), will help analyze regulatory mechanisms in specific biological systems...
  12. ncbi request reprint Transcriptional regulatory networks in Saccharomyces cerevisiae
    Tong Ihn Lee
    Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA 02142, USA
    Science 298:799-804. 2002
    ..Our results reveal that eukaryotic cellular functions are highly connected through networks of transcriptional regulators that regulate other transcriptional regulators...
  13. ncbi request reprint Computational discovery of gene modules and regulatory networks
    Ziv Bar-Joseph
    MIT Computer Science and Artificial Intelligence Laboratory, 200 Technology Square, Cambridge, Massachusetts 02139, USA
    Nat Biotechnol 21:1337-42. 2003
    ..We also present a genome-wide location analysis data set for regulators in yeast cells treated with rapamycin, and use the GRAM algorithm to provide biological insights into this regulatory network..