L M Ward

Summary

Affiliation: Children's Hospital of Eastern Ontario
Country: Canada

Publications

  1. pmc Vitamin D deficiency in the 21st century: a persistent problem among Canadian infants and mothers
    Leanne M Ward
    Canadian Institutes for Health Research New Investigator, University of Ottawa, and Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 172:769-70. 2005
  2. pmc DMP1 C-terminal mutant mice recapture the human ARHR tooth phenotype
    Baichun Jiang
    Institute of Medical Genetics, Shandong University School of Medicine, Jinan, People s Republic of China
    J Bone Miner Res 25:2155-64. 2010
  3. pmc High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy
    Nathalie Alos
    Universite de Montreal, Canada
    J Clin Oncol 30:2760-7. 2012
  4. doi request reprint Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel disease
    L M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
    Osteoporos Int 21:331-7. 2010
  5. pmc Vitamin D-deficiency rickets among children in Canada
    Leanne M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont
    CMAJ 177:161-6. 2007
  6. ncbi request reprint The use of intravenous bisphosphonate therapy to treat vertebral fractures due to osteoporosis among boys with Duchenne muscular dystrophy
    A M Sbrocchi
    Division of Endocrinology, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON, Canada
    Osteoporos Int 23:2703-11. 2012
  7. ncbi request reprint Osteopathia striata with cranial sclerosis: clinical, radiological, and bone histological findings in an adolescent girl
    L M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada
    Am J Med Genet A 129:8-12. 2004
  8. ncbi request reprint Osteoporosis due to glucocorticoid use in children with chronic illness
    Leanne M Ward
    Department of Pediatrics, University of Ottawa and Division of Endocrinology, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Horm Res 64:209-21. 2005
  9. ncbi request reprint Renal phosphate--wasting disorders in childhood
    Leanne M Ward
    Division of Endocrinology and Metabolism, Children s Hospital of Eastern Ontario, and Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Pediatr Endocrinol Rev 2:342-50. 2005
  10. pmc Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program
    Jacqueline Halton
    University of Ottawa, Ontario, Canada
    J Bone Miner Res 24:1326-34. 2009

Collaborators

Detail Information

Publications17

  1. pmc Vitamin D deficiency in the 21st century: a persistent problem among Canadian infants and mothers
    Leanne M Ward
    Canadian Institutes for Health Research New Investigator, University of Ottawa, and Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 172:769-70. 2005
  2. pmc DMP1 C-terminal mutant mice recapture the human ARHR tooth phenotype
    Baichun Jiang
    Institute of Medical Genetics, Shandong University School of Medicine, Jinan, People s Republic of China
    J Bone Miner Res 25:2155-64. 2010
    ..Last, the in vitro and in vivo data support a role of odontoblasts in the control of fibroblast growth factor 23 (FGF-23) regulation during early postnatal development, although this regulation on Pi homeostasis is likely limited...
  3. pmc High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy
    Nathalie Alos
    Universite de Montreal, Canada
    J Clin Oncol 30:2760-7. 2012
    ..Vertebral fractures due to osteoporosis are a potential complication of childhood acute lymphoblastic leukemia (ALL). To date, the incidence of vertebral fractures during ALL treatment has not been reported...
  4. doi request reprint Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel disease
    L M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
    Osteoporos Int 21:331-7. 2010
    ..It is possible that low mechanical stimulation due to inadequate muscle mass contributes to the bone deficit...
  5. pmc Vitamin D-deficiency rickets among children in Canada
    Leanne M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont
    CMAJ 177:161-6. 2007
    ..We sought to determine the incidence and clinical characteristics of vitamin D-deficiency rickets among children living in Canada...
  6. ncbi request reprint The use of intravenous bisphosphonate therapy to treat vertebral fractures due to osteoporosis among boys with Duchenne muscular dystrophy
    A M Sbrocchi
    Division of Endocrinology, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON, Canada
    Osteoporos Int 23:2703-11. 2012
    ..In this retrospective observational study of seven boys, 2 years of intravenous bisphosphonate therapy was associated with back pain improvement and stabilization or increases in the height ratios of fractured vertebrae...
  7. ncbi request reprint Osteopathia striata with cranial sclerosis: clinical, radiological, and bone histological findings in an adolescent girl
    L M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada
    Am J Med Genet A 129:8-12. 2004
    ..Thus, studies of bone metabolism did not explain why bone mass is increased in most skeletal areas of this patient. Cranial histology points to exuberant periosteal bone formation as a potential cause of the cranial sclerosis...
  8. ncbi request reprint Osteoporosis due to glucocorticoid use in children with chronic illness
    Leanne M Ward
    Department of Pediatrics, University of Ottawa and Division of Endocrinology, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Horm Res 64:209-21. 2005
    ..Following an understanding of the natural history of GC-induced osteoporosis in children, randomized, placebo-controlled prevention and intervention trials will be the next step toward the development of clinical practice guidelines...
  9. ncbi request reprint Renal phosphate--wasting disorders in childhood
    Leanne M Ward
    Division of Endocrinology and Metabolism, Children s Hospital of Eastern Ontario, and Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Pediatr Endocrinol Rev 2:342-50. 2005
    ..The information may be invaluable in the complex diagnosis and successful treatment of OHO and hereditary hypophosphatemias of childhood...
  10. pmc Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program
    Jacqueline Halton
    University of Ottawa, Ontario, Canada
    J Bone Miner Res 24:1326-34. 2009
    ..5-14.5). These results show that vertebral compression is an under-recognized complication of newly diagnosed ALL. Whether the fractures will resolve through bone growth during or after leukemia chemotherapy remains to be determined...
  11. ncbi request reprint Resolution of severe, adolescent-onset hypophosphatemic rickets following resection of an FGF-23-producing tumour of the distal ulna
    L M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
    Bone 34:905-11. 2004
    ....
  12. pmc Skeletal findings in children recently initiating glucocorticoids for the treatment of nephrotic syndrome
    J Feber
    University of Ottawa, Ottawa, ON, Canada
    Osteoporos Int 23:751-60. 2012
    ..We found an inverse relationship between glucocorticoid exposure and spine areal bone mineral density (BMD) Z-score and a low rate of vertebral deformities (8%)...
  13. ncbi request reprint Effect of calcium and vitamin D supplementation on bone mineral density in children with inflammatory bowel disease
    Eric I Benchimol
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada
    J Pediatr Gastroenterol Nutr 45:538-45. 2007
    ..The purpose of this study was to evaluate the effect of calcium and vitamin D2 supplementation on bone mineral density (BMD) in children with inflammatory bowel disease (IBD)...
  14. pmc Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism
    Jian Q Feng
    Oral Biology, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    Nat Genet 38:1310-5. 2006
    ..Our findings suggest a bone-renal axis that is central to guiding proper mineral metabolism...
  15. doi request reprint Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official Positions
    Catherine M Gordon
    Division of Endocrinology, Children s Hospital Boston, Boston, MA 02115, USA
    J Clin Densitom 11:43-58. 2008
    ..The rationale and evidence for development of the Official Positions are provided. Given the sparse data currently available in many of these areas, it is likely that these positions will change over time as new data become available...
  16. ncbi request reprint Sensitivity of fibroblast growth factor 23 measurements in tumor-induced osteomalacia
    Erik A Imel
    Indiana University School of Medicine, 541 North Clinical Drive, Clinical Building 459, Indianapolis, Indianapolis 46202, USA
    J Clin Endocrinol Metab 91:2055-61. 2006
    ..Fibroblast growth factor 23 (FGF23) is a phosphaturic protein overexpressed in tumors that cause TIO and is, at least partly, responsible for the manifestations of TIO...
  17. ncbi request reprint Osteogenesis imperfecta type VI: a form of brittle bone disease with a mineralization defect
    Francis H Glorieux
    Shriners Hospital for Children, and Department of Surgery, McGill University, Montreal, Quebec, Canada
    J Bone Miner Res 17:30-8. 2002
    ..The underlying genetic defect remains to be elucidated...