Research Topics
| L M WardSummaryAffiliation: Children's Hospital of Eastern Ontario Country: Canada Publications
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Detail Information
Publications
Vitamin D deficiency in the 21st century: a persistent problem among Canadian infants and mothersLeanne M Ward
Canadian Institutes for Health Research New Investigator, University of Ottawa, and Children's Hospital of Eastern Ontario, Ottawa, Ont
CMAJ 172:769-70. 2005
High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapyNathalie Alos
Universite de Montreal, Canada
J Clin Oncol 30:2760-7. 2012..Vertebral fractures due to osteoporosis are a potential complication of childhood acute lymphoblastic leukemia (ALL). To date, the incidence of vertebral fractures during ALL treatment has not been reported...
Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel diseaseL M Ward
Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
Osteoporos Int 21:331-7. 2010..It is possible that low mechanical stimulation due to inadequate muscle mass contributes to the bone deficit...
Vitamin D-deficiency rickets among children in CanadaLeanne M Ward
Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont
CMAJ 177:161-6. 2007..We sought to determine the incidence and clinical characteristics of vitamin D-deficiency rickets among children living in Canada...
Osteopathia striata with cranial sclerosis: clinical, radiological, and bone histological findings in an adolescent girlL M Ward
Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Canada
Am J Med Genet A 129:8-12. 2004..Thus, studies of bone metabolism did not explain why bone mass is increased in most skeletal areas of this patient. Cranial histology points to exuberant periosteal bone formation as a potential cause of the cranial sclerosis...
Osteoporosis due to glucocorticoid use in children with chronic illnessLeanne M Ward
Department of Pediatrics, University of Ottawa and Division of Endocrinology, Children s Hospital of Eastern Ontario, Ottawa, Canada
Horm Res 64:209-21. 2005..Following an understanding of the natural history of GC-induced osteoporosis in children, randomized, placebo-controlled prevention and intervention trials will be the next step toward the development of clinical practice guidelines...
Renal phosphate--wasting disorders in childhoodLeanne M Ward
Division of Endocrinology and Metabolism, Children s Hospital of Eastern Ontario, and Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
Pediatr Endocrinol Rev 2:342-50. 2005..The information may be invaluable in the complex diagnosis and successful treatment of OHO and hereditary hypophosphatemias of childhood...
Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research programJacqueline Halton
University of Ottawa, Ontario, Canada
J Bone Miner Res 24:1326-34. 2009..5-14.5). These results show that vertebral compression is an under-recognized complication of newly diagnosed ALL. Whether the fractures will resolve through bone growth during or after leukemia chemotherapy remains to be determined...
The use of intravenous bisphosphonate therapy to treat vertebral fractures due to osteoporosis among boys with Duchenne muscular dystrophyA M Sbrocchi
Division of Endocrinology, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON, Canada
Osteoporos Int 23:2703-11. 2012..In this retrospective observational study of seven boys, 2 years of intravenous bisphosphonate therapy was associated with back pain improvement and stabilization or increases in the height ratios of fractured vertebrae...
Skeletal findings in children recently initiating glucocorticoids for the treatment of nephrotic syndromeJ Feber
University of Ottawa, Ottawa, ON, Canada
Osteoporos Int 23:751-60. 2012..We found an inverse relationship between glucocorticoid exposure and spine areal bone mineral density (BMD) Z-score and a low rate of vertebral deformities (8%)...
Resolution of severe, adolescent-onset hypophosphatemic rickets following resection of an FGF-23-producing tumour of the distal ulnaL M Ward
Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
Bone 34:905-11. 2004....
Effect of calcium and vitamin D supplementation on bone mineral density in children with inflammatory bowel diseaseEric I Benchimol
Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada
J Pediatr Gastroenterol Nutr 45:538-45. 2007..The purpose of this study was to evaluate the effect of calcium and vitamin D2 supplementation on bone mineral density (BMD) in children with inflammatory bowel disease (IBD)...
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolismJian Q Feng
Oral Biology, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
Nat Genet 38:1310-5. 2006..Our findings suggest a bone-renal axis that is central to guiding proper mineral metabolism...
Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official PositionsCatherine M Gordon
Division of Endocrinology, Children s Hospital Boston, Boston, MA 02115, USA
J Clin Densitom 11:43-58. 2008..The rationale and evidence for development of the Official Positions are provided. Given the sparse data currently available in many of these areas, it is likely that these positions will change over time as new data become available...
Sensitivity of fibroblast growth factor 23 measurements in tumor-induced osteomalaciaErik A Imel
Indiana University School of Medicine, 541 North Clinical Drive, Clinical Building 459, Indianapolis, Indianapolis 46202, USA
J Clin Endocrinol Metab 91:2055-61. 2006..Normal FGF23 concentrations should be interpreted in relation to the serum phosphate and 1,25-dihydryxyvitamin-D concentrations...
Osteogenesis imperfecta type VI: a form of brittle bone disease with a mineralization defectFrancis H Glorieux
Shriners Hospital for Children, and Department of Surgery, McGill University, Montreal, Quebec, Canada
J Bone Miner Res 17:30-8. 2002..The underlying genetic defect remains to be elucidated...
