R Slinger

Summary

Affiliation: Children's Hospital of Eastern Ontario
Country: Canada

Publications

  1. ncbi Evaluation of the QuickLab RSV test, a new rapid lateral-flow immunoassay for detection of respiratory syncytial virus antigen
    Robert Slinger
    Division of Infectious Disease, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, Ontario K1H 8L1, Canada
    J Clin Microbiol 42:3731-3. 2004
  2. ncbi Successful nanolitre real-time PCR detection of respiratory pathogens in clinical specimens
    R Slinger
    Children s Hospital of Eastern Ontario, Ottawa, ON, Canada
    Clin Microbiol Infect 18:E286-8. 2012
  3. ncbi Rapid detection of Bordetella pertussis and Bordetella parapertussis in clinical and molecular proficiency panel specimens with a novel intercalating dye-based PCR assay
    Robert Slinger
    Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
    Scand J Infect Dis 43:968-71. 2011
  4. ncbi Cloxacillin versus vancomycin for presumed late-onset sepsis in the Neonatal Intensive Care Unit and the impact upon outcome of coagulase negative staphylococcal bacteremia: a retrospective cohort study
    Sarah L Lawrence
    Department of Obstetrics, Gynecology and Newborn Care, The Ottawa Hospital, Ottawa, Ontario, Canada
    BMC Pediatr 5:49. 2005
  5. ncbi Rapid PCR detection of group A Streptococcus from flocked throat swabs: a retrospective clinical study
    Robert Slinger
    Department of Laboratory Medicine, Children s Hospital of Eastern Ontario, University of Ottawa, Ontario, Canada
    Ann Clin Microbiol Antimicrob 10:33. 2011
  6. ncbi Pyrosequencing assay to rapidly detect clarithromycin resistance mutations in Canadian Helicobacter pylori isolates
    R Slinger
    Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada
    Can J Gastroenterol 23:609-12. 2009
  7. ncbi Pyrosequencing of a recA gene variable region for Burkholderia cepacia complex genomovar identification
    Robert Slinger
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada K1H 8MS
    Diagn Microbiol Infect Dis 58:379-84. 2007
  8. ncbi High-resolution melting assay for the detection of gyrA mutations causing quinolone resistance in Salmonella enterica serovars Typhi and Paratyphi
    Robert Slinger
    Division of Bacteriology, Department of Pathology and Laboratory Medicine, Children s Hospital of Eastern Ontario, Ottawa, ON, Canada K1H 8L1
    Diagn Microbiol Infect Dis 57:455-8. 2007
  9. ncbi Multiple combination antibiotic susceptibility testing of nontypeable Haemophilus influenzae biofilms
    Robert Slinger
    Department of Pediatrics, Ottawa, Ontario, Canada K1H 8L1
    Diagn Microbiol Infect Dis 56:247-53. 2006
  10. ncbi Suboptimal clinical response to ciprofloxacin in patients with enteric fever due to Salmonella spp. with reduced fluoroquinolone susceptibility: a case series
    Robert Slinger
    Division of Infectious Disease, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON, Canada
    BMC Infect Dis 4:36. 2004

Collaborators

Detail Information

Publications15

  1. ncbi Evaluation of the QuickLab RSV test, a new rapid lateral-flow immunoassay for detection of respiratory syncytial virus antigen
    Robert Slinger
    Division of Infectious Disease, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, Ontario K1H 8L1, Canada
    J Clin Microbiol 42:3731-3. 2004
    ..001). We conclude that the QuickLab RSV test has sensitivity similar to that of the DFA assay and better than that of the DIR assay. QuickLab testing is also simpler to perform and interpret than both DFA and DIR testing...
  2. ncbi Successful nanolitre real-time PCR detection of respiratory pathogens in clinical specimens
    R Slinger
    Children s Hospital of Eastern Ontario, Ottawa, ON, Canada
    Clin Microbiol Infect 18:E286-8. 2012
    ..RSV nanolitre PCR was also 100% sensitive (21/21; 95% CI, 85-100%) and specific (25/25; 95%, CI 87-100%). Respiratory pathogens can be successfully detected in clinical specimens using nanolitre-volume PCR...
  3. ncbi Rapid detection of Bordetella pertussis and Bordetella parapertussis in clinical and molecular proficiency panel specimens with a novel intercalating dye-based PCR assay
    Robert Slinger
    Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
    Scand J Infect Dis 43:968-71. 2011
    ..The assay can be performed in 1 h including DNA extraction. The new assay thus offers a simple and rapid alternative for the detection of B. pertussis and B. parapertussis...
  4. ncbi Cloxacillin versus vancomycin for presumed late-onset sepsis in the Neonatal Intensive Care Unit and the impact upon outcome of coagulase negative staphylococcal bacteremia: a retrospective cohort study
    Sarah L Lawrence
    Department of Obstetrics, Gynecology and Newborn Care, The Ottawa Hospital, Ottawa, Ontario, Canada
    BMC Pediatr 5:49. 2005
    ..The objective of this study was to compare duration of CONS sepsis and mortality before and after implementation of a policy of selective vancomycin use and compare use of vancomycin between the 2 time periods...
  5. ncbi Rapid PCR detection of group A Streptococcus from flocked throat swabs: a retrospective clinical study
    Robert Slinger
    Department of Laboratory Medicine, Children s Hospital of Eastern Ontario, University of Ottawa, Ontario, Canada
    Ann Clin Microbiol Antimicrob 10:33. 2011
    ..Very few molecular methods for detection of GAS in clinical throat swab specimens have been described...
  6. ncbi Pyrosequencing assay to rapidly detect clarithromycin resistance mutations in Canadian Helicobacter pylori isolates
    R Slinger
    Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada
    Can J Gastroenterol 23:609-12. 2009
    ..Mutations at positions 2142 or 2143 in the twocopy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens...
  7. ncbi Pyrosequencing of a recA gene variable region for Burkholderia cepacia complex genomovar identification
    Robert Slinger
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada K1H 8MS
    Diagn Microbiol Infect Dis 58:379-84. 2007
    ..Three Burkholderia multivorans isolates were identified as B. multivorans/Burkholderia ambifaria, indicating that additional identification methods may be needed for some B. multivorans strains...
  8. ncbi High-resolution melting assay for the detection of gyrA mutations causing quinolone resistance in Salmonella enterica serovars Typhi and Paratyphi
    Robert Slinger
    Division of Bacteriology, Department of Pathology and Laboratory Medicine, Children s Hospital of Eastern Ontario, Ottawa, ON, Canada K1H 8L1
    Diagn Microbiol Infect Dis 57:455-8. 2007
    ..The presence of gyrA mutations led to small but consistent changes in amplicon melting temperatures that allowed quinolone-resistant isolates to be differentiated from susceptible ones...
  9. ncbi Multiple combination antibiotic susceptibility testing of nontypeable Haemophilus influenzae biofilms
    Robert Slinger
    Department of Pediatrics, Ottawa, Ontario, Canada K1H 8L1
    Diagn Microbiol Infect Dis 56:247-53. 2006
    ..Biofilm testing reveals differences in effectiveness among antibiotics not apparent from conventional susceptibility testing, and suggests novel antibiotic regimens that could be studied for treatment of OME...
  10. ncbi Suboptimal clinical response to ciprofloxacin in patients with enteric fever due to Salmonella spp. with reduced fluoroquinolone susceptibility: a case series
    Robert Slinger
    Division of Infectious Disease, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON, Canada
    BMC Infect Dis 4:36. 2004
    ..Delayed treatment response to fluoroquinolones has been noted, especially in cases of enteric fever due to such strains. We reviewed the ciprofloxacin susceptibility and clinical outcome of our recent enteric fever cases...
  11. ncbi Transfusion-transmitted malaria in Canada
    R Slinger
    Centre for Infectious Disease Prevention and Control, Population and Public Health Branch, Health Canada, Ottawa, Ont
    CMAJ 164:377-9. 2001
    ..Although very rare, this diagnosis should be considered in transfusion recipients who have undiagnosed symptoms consistent with malaria. Thick and thin blood smears should be urgently examined to exclude this possibility...
  12. ncbi Infection with Burkholderia cepacia complex bacteria and pulmonary exacerbations of cystic fibrosis
    Melissa St Denis
    The Ottawa Hospital, General Campus, 501 Smyth Rd, Ottawa, ON, Canada
    Chest 131:1188-96. 2007
    ..Our objective was to determine whether pulmonary exacerbations of CF are associated with acquisition of new B cepacia strains or with B cepacia strain replacement...
  13. ncbi Assessment of flocked swabs for use in identification of streptococcal pharyngitis
    David M Goldfarb
    Division of Infectious Diseases, Children s Hospital of Eastern Ontario, University of Ottawa, Ontario, Canada
    J Clin Microbiol 47:3029-30. 2009
    ..Sensitivity was higher for flocked swabs, but this did not reach statistical significance. We conclude that flocked swabs can be used in place of traditional swabs for diagnosis of streptococcal pharyngitis...
  14. ncbi Effectiveness of honey on Staphylococcus aureus and Pseudomonas aeruginosa biofilms
    Talal Alandejani
    Department of Otolaryngology, University of Ottawa, and Childrens Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Otolaryngol Head Neck Surg 141:114-8. 2009
    ..As well, honey has been used as an effective topical antimicrobial agent for years. Our objective is to determine the in vitro effect of honey against biofilms produced by PA and SA...
  15. ncbi Tache noire
    Nick Daneman
    Department of Medicine, Infectious Diseases, Sunnybrook Health Sciences Centre, Toronto, Ont
    CMAJ 178:841. 2008