Nicole Le Saux

Summary

Affiliation: Children's Hospital of Eastern Ontario
Country: Canada

Publications

  1. ncbi Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, 2001-2003
    David Scheifele
    British Columbia s Children s Hospital, 4500 Oak St, Vancouver BC V6H 3N1
    CMAJ 172:53-6. 2005
  2. ncbi The hidden costs and characteristics of childhood rotavirus emergency visits in Canada
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario and CHEO Research Institute, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 31:159-63. 2012
  3. ncbi Antimicrobial use in febrile children diagnosed with respiratory tract illness in an emergency department
    N Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Canada
    Pediatr Infect Dis J 18:1078-80. 1999
  4. ncbi Evaluating the benefits of antimicrobial prophylaxis to prevent urinary tract infections in children: a systematic review
    N Le Saux
    Thomas C Chalmers Centre for Systematic Reviews, Children s Hospital of Eastern Ontario Research Institute, Ottawa
    CMAJ 163:523-9. 2000
  5. ncbi Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic review
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ontario, Canada
    BMC Infect Dis 2:16. 2002
  6. ncbi The treatment of acute bacterial sinusitis: no change is good medicine
    Nicole Le Saux
    Department of Infectious Diseases, Children's Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 178:865-6. 2008
  7. ncbi A randomized, double-blind, placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 172:335-41. 2005
  8. ncbi Decrease in hospital admissions for febrile seizures and reports of hypotonic-hyporesponsive episodes presenting to hospital emergency departments since switching to acellular pertussis vaccine in Canada: a report from IMPACT
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Pediatrics 112:e348. 2003
  9. ncbi Substantial morbidity for hospitalized children with community-acquired rotavirus infections: 2005-2007 IMPACT surveillance in Canadian hospitals
    Nicole Le Saux
    Division of Infectious Diseases, CHEO Research Institute, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 29:879-82. 2010
  10. ncbi Effect of point of care information on inpatient management of bronchiolitis
    W James King
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    BMC Pediatr 7:4. 2007

Detail Information

Publications25

  1. ncbi Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, 2001-2003
    David Scheifele
    British Columbia s Children s Hospital, 4500 Oak St, Vancouver BC V6H 3N1
    CMAJ 172:53-6. 2005
    ..We report on the causes of Hib infections among vaccinated and unvaccinated children between 2001 and 2003 in Canada...
  2. ncbi The hidden costs and characteristics of childhood rotavirus emergency visits in Canada
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario and CHEO Research Institute, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 31:159-63. 2012
    ..Our objective was to describe rotavirus ED visits to include healthcare utilization pre- and postvisit to estimate true societal costs...
  3. ncbi Antimicrobial use in febrile children diagnosed with respiratory tract illness in an emergency department
    N Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Canada
    Pediatr Infect Dis J 18:1078-80. 1999
    ....
  4. ncbi Evaluating the benefits of antimicrobial prophylaxis to prevent urinary tract infections in children: a systematic review
    N Le Saux
    Thomas C Chalmers Centre for Systematic Reviews, Children s Hospital of Eastern Ontario Research Institute, Ottawa
    CMAJ 163:523-9. 2000
    ..The aim of this review was to systematically examine the available evidence for the effectiveness of this intervention...
  5. ncbi Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic review
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ontario, Canada
    BMC Infect Dis 2:16. 2002
    ..Currently, there is no consensus on the route and duration of antimicrobial therapy to treat AHO...
  6. ncbi The treatment of acute bacterial sinusitis: no change is good medicine
    Nicole Le Saux
    Department of Infectious Diseases, Children's Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 178:865-6. 2008
  7. ncbi A randomized, double-blind, placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 172:335-41. 2005
    ..In this double-blind noninferiority trial, we compared clinical improvement rates at 14 days for children (6 months to 5 years of age) with acute otitis media who were randomly assigned to receive amoxicillin or placebo...
  8. ncbi Decrease in hospital admissions for febrile seizures and reports of hypotonic-hyporesponsive episodes presenting to hospital emergency departments since switching to acellular pertussis vaccine in Canada: a report from IMPACT
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Pediatrics 112:e348. 2003
    ..We hypothesized that the change would result in a decrease in hospitalization rates for seizures and reports of hypotonic-hyporesponsive episodes (HHEs) temporally related to pertussis vaccination...
  9. ncbi Substantial morbidity for hospitalized children with community-acquired rotavirus infections: 2005-2007 IMPACT surveillance in Canadian hospitals
    Nicole Le Saux
    Division of Infectious Diseases, CHEO Research Institute, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 29:879-82. 2010
    ..6%) had significant dehydration, almost one-fifth (19%) had clinical sepsis and 7% had seizures at presentation. The median hospital stay was 3.4 days. Severe clinical presentations are less commonly described in surveillance programs...
  10. ncbi Effect of point of care information on inpatient management of bronchiolitis
    W James King
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    BMC Pediatr 7:4. 2007
    ..We studied the effects of access to point-of-care medical evidence in a computerised physician order entry system (CPOE) on management and clinical outcome of children with bronchiolitis...
  11. ncbi Empyema associated with community-acquired pneumonia: a Pediatric Investigator's Collaborative Network on Infections in Canada (PICNIC) study
    Joanne M Langley
    Department of Pediatrics, Dalhousie University, Halifax, Canada
    BMC Infect Dis 8:129. 2008
    ..We reviewed the epidemiology and clinical management of empyema at 8 pediatric hospitals in a period before the widespread implementation of universal infant heptavalent pneumococcal vaccine programs in Canada...
  12. ncbi Profile of serogroup Y meningococcal infections in Canada: Implications for vaccine selection
    Nicole Le Saux
    Children s Hospital of Eastern Ontario Research Institute and the University of Ottawa, Ottawa, Ontario
    Can J Infect Dis Med Microbiol 20:e130-4. 2009
    ..In the present paper, recent surveillance data on invasive meningococcal disease across Canada are summarized...
  13. ncbi Factors influencing childhood influenza immunization
    Vincent J Grant
    Department of Pediatrics, Children s Hospital of Eastern Ontario and the University of Ottawa, Ottawa, Ont
    CMAJ 168:39-41. 2003
    ..7, 95% confidence interval [CI] 1.8-12.6). Children of parents who discussed immunization with a physician were more likely to be immunized than those who had not discussed immunization with a physician (OR 6.8, 95% CI 2.4-19.2)...
  14. ncbi Characteristics and outcome of infants with candiduria in neonatal intensive care - a Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study
    Joan L Robinson
    Department of Pediatrics, Alberta Children s Hospital Calgary, Alberta, Canada
    BMC Infect Dis 9:183. 2009
    ..There is limited information in the literature on the presentation and prognosis of candidal urinary tract infection (UTI) in infants in the neonatal intensive care unit (NICU)...
  15. ncbi Maternal respiratory syncytial virus antibody titers: season and children matter
    Nicole Le Saux
    Division of Infectious Diseases, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 22:563-4. 2003
    ..Mean antibody titers were significantly higher between April and September and significantly higher in women who already had children at home...
  16. ncbi A point prevalence survey of health care-associated infections in Canadian pediatric inpatients
    Katie Rutledge-Taylor
    Canadian Field Epidemiology Program, Public Health Agency of Canada, Ottawa, Ontario, Canada
    Am J Infect Control 40:491-6. 2012
    ..The objective of this point prevalence study was to assess the burden of HAIs in the Canadian pediatric population, updating results reported from a similar study conducted in 2002...
  17. ncbi A Comparison of group A Streptococcus versus Streptococcus pneumoniae pneumonia
    Nawal Al-Kaabi
    Chalmers Research Group, Statistical Division, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 25:1008-12. 2006
    ..Compared with patients with SP pneumonia, it appears to cause more effusions and morbidity. The organism is also more frequently recovered from pleural fluid...
  18. ncbi Miller Fisher syndrome in a toddler with influenza A (pH1N1) infection
    Cecilia T Costiniuk
    University of Ottawa, Faculty of Medicine, Division of Infectious Diseases, Ottawa, Ontario, Canada
    J Child Neurol 26:385-8. 2011
    ..During pandemics, one may expect to see an increased incidence of uncommon neurologic complications of influenza...
  19. ncbi A systematic review of the effectiveness of antimicrobial rinse-free hand sanitizers for prevention of illness-related absenteeism in elementary school children
    Emily Meadows
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    BMC Public Health 4:50. 2004
    ..Currently, alternative hand hygiene techniques are being considered, and one such technique is the use of antimicrobial rinse-free hand sanitizers...
  20. ncbi Fifteen-year-old girl with fever, headache and vomiting
    Rebecca Sherlock
    Department of Paediatrics, Infectious Disease, The Children's Hospital of Eastern Ontario, Ottawa, Canada
    Pediatr Infect Dis J 21:439, 449-50. 2002
  21. ncbi Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient data
    Laura Koopman
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 134:128-32. 2008
    ..To determine predictors of the development of asymptomatic middle ear effusion (MEE) in children with acute otitis media (AOM) and to assess the effect of antibiotic therapy in preventing the development of MEE in these children...
  22. ncbi The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation
    Barbara J Law
    Department of Pediatrics and Child Health, University of Manitoba and the Winnipeg Health Sciences Center, Winnipeg, Canada
    Pediatr Infect Dis J 23:806-14. 2004
    ..This study sought to identify independent risk factors for hospitalization for RSV infection...
  23. ncbi Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient data
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Pediatrics 119:579-85. 2007
    ..The goal was to determine the predictors of a prolonged course for children with acute otitis media...
  24. ncbi Lack of evidence of encephalopathy related to pertussis vaccine: active surveillance by IMPACT, Canada, 1993-2002
    Dorothy L Moore
    Montreal Children s Hospital, McGill University Health Centre, Quebec, Canada
    Pediatr Infect Dis J 23:568-71. 2004
    ..Seven cases of encephalopathy began within 7 days after pertussis vaccination, but a more likely cause was found in each instance. No attributable case followed administration of >6.5 million doses of vaccine...
  25. ncbi Surveillance for influenza admissions among children hospitalized in Canadian immunization monitoring program active centers, 2003-2004
    Dorothy L Moore
    Infectious Diseases Division, Montreal Children s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Pediatrics 118:e610-9. 2006
    ....