Nicole Le Saux

Summary

Affiliation: Children's Hospital of Eastern Ontario
Country: Canada

Publications

  1. pmc Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, 2001-2003
    David Scheifele
    British Columbia s Children s Hospital, 4500 Oak St, Vancouver BC V6H 3N1
    CMAJ 172:53-6. 2005
  2. pmc Molecular characterization of rotavirus isolates from select Canadian pediatric hospitals
    Andrew McDermid
    National Microbiology Laboratory, Winnipeg, Canada
    BMC Infect Dis 12:306. 2012
  3. ncbi request reprint The hidden costs and characteristics of childhood rotavirus emergency visits in Canada
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario and CHEO Research Institute, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 31:159-63. 2012
  4. ncbi request reprint Substantial morbidity for hospitalized children with community-acquired rotavirus infections: 2005-2007 IMPACT surveillance in Canadian hospitals
    Nicole Le Saux
    Division of Infectious Diseases, CHEO Research Institute, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 29:879-82. 2010
  5. pmc The treatment of acute bacterial sinusitis: no change is good medicine
    Nicole Le Saux
    Department of Infectious Diseases, Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 178:865-6. 2008
  6. ncbi request reprint Antimicrobial use in febrile children diagnosed with respiratory tract illness in an emergency department
    N Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Canada
    Pediatr Infect Dis J 18:1078-80. 1999
  7. pmc A randomized, double-blind, placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 172:335-41. 2005
  8. ncbi request reprint Decrease in hospital admissions for febrile seizures and reports of hypotonic-hyporesponsive episodes presenting to hospital emergency departments since switching to acellular pertussis vaccine in Canada: a report from IMPACT
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Pediatrics 112:e348. 2003
  9. pmc Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic review
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ontario, Canada
    BMC Infect Dis 2:16. 2002
  10. pmc Evaluating the benefits of antimicrobial prophylaxis to prevent urinary tract infections in children: a systematic review
    N Le Saux
    Thomas C Chalmers Centre for Systematic Reviews, Children s Hospital of Eastern Ontario Research Institute, Ottawa
    CMAJ 163:523-9. 2000

Detail Information

Publications27

  1. pmc Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, 2001-2003
    David Scheifele
    British Columbia s Children s Hospital, 4500 Oak St, Vancouver BC V6H 3N1
    CMAJ 172:53-6. 2005
    ..We report on the causes of Hib infections among vaccinated and unvaccinated children between 2001 and 2003 in Canada...
  2. pmc Molecular characterization of rotavirus isolates from select Canadian pediatric hospitals
    Andrew McDermid
    National Microbiology Laboratory, Winnipeg, Canada
    BMC Infect Dis 12:306. 2012
    ..Secondly we identified rotavirus strains that differed genetically from those included in the vaccines and which could affect vaccine effectiveness...
  3. ncbi request reprint The hidden costs and characteristics of childhood rotavirus emergency visits in Canada
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario and CHEO Research Institute, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 31:159-63. 2012
    ..Our objective was to describe rotavirus ED visits to include healthcare utilization pre- and postvisit to estimate true societal costs...
  4. ncbi request reprint Substantial morbidity for hospitalized children with community-acquired rotavirus infections: 2005-2007 IMPACT surveillance in Canadian hospitals
    Nicole Le Saux
    Division of Infectious Diseases, CHEO Research Institute, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 29:879-82. 2010
    ..6%) had significant dehydration, almost one-fifth (19%) had clinical sepsis and 7% had seizures at presentation. The median hospital stay was 3.4 days. Severe clinical presentations are less commonly described in surveillance programs...
  5. pmc The treatment of acute bacterial sinusitis: no change is good medicine
    Nicole Le Saux
    Department of Infectious Diseases, Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 178:865-6. 2008
  6. ncbi request reprint Antimicrobial use in febrile children diagnosed with respiratory tract illness in an emergency department
    N Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Canada
    Pediatr Infect Dis J 18:1078-80. 1999
    ....
  7. pmc A randomized, double-blind, placebo-controlled noninferiority trial of amoxicillin for clinically diagnosed acute otitis media in children 6 months to 5 years of age
    Nicole Le Saux
    Department of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ont
    CMAJ 172:335-41. 2005
    ..In this double-blind noninferiority trial, we compared clinical improvement rates at 14 days for children (6 months to 5 years of age) with acute otitis media who were randomly assigned to receive amoxicillin or placebo...
  8. ncbi request reprint Decrease in hospital admissions for febrile seizures and reports of hypotonic-hyporesponsive episodes presenting to hospital emergency departments since switching to acellular pertussis vaccine in Canada: a report from IMPACT
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Pediatrics 112:e348. 2003
    ..We hypothesized that the change would result in a decrease in hospitalization rates for seizures and reports of hypotonic-hyporesponsive episodes (HHEs) temporally related to pertussis vaccination...
  9. pmc Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic review
    Nicole Le Saux
    Department of Pediatrics, University of Ottawa, Ontario, Canada
    BMC Infect Dis 2:16. 2002
    ..Currently, there is no consensus on the route and duration of antimicrobial therapy to treat AHO...
  10. pmc Evaluating the benefits of antimicrobial prophylaxis to prevent urinary tract infections in children: a systematic review
    N Le Saux
    Thomas C Chalmers Centre for Systematic Reviews, Children s Hospital of Eastern Ontario Research Institute, Ottawa
    CMAJ 163:523-9. 2000
    ..The aim of this review was to systematically examine the available evidence for the effectiveness of this intervention...
  11. pmc Effect of point of care information on inpatient management of bronchiolitis
    W James King
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    BMC Pediatr 7:4. 2007
    ..We studied the effects of access to point-of-care medical evidence in a computerised physician order entry system (CPOE) on management and clinical outcome of children with bronchiolitis...
  12. doi request reprint A point prevalence survey of health care-associated infections in Canadian pediatric inpatients
    Katie Rutledge-Taylor
    Canadian Field Epidemiology Program, Public Health Agency of Canada, Ottawa, Ontario, Canada
    Am J Infect Control 40:491-6. 2012
    ..The objective of this point prevalence study was to assess the burden of HAIs in the Canadian pediatric population, updating results reported from a similar study conducted in 2002...
  13. pmc Empyema associated with community-acquired pneumonia: a Pediatric Investigator's Collaborative Network on Infections in Canada (PICNIC) study
    Joanne M Langley
    Department of Pediatrics, Dalhousie University, Halifax, Canada
    BMC Infect Dis 8:129. 2008
    ..We reviewed the epidemiology and clinical management of empyema at 8 pediatric hospitals in a period before the widespread implementation of universal infant heptavalent pneumococcal vaccine programs in Canada...
  14. pmc Profile of serogroup Y meningococcal infections in Canada: Implications for vaccine selection
    Nicole Le Saux
    Children s Hospital of Eastern Ontario Research Institute and the University of Ottawa, Ottawa, Ontario
    Can J Infect Dis Med Microbiol 20:e130-4. 2009
    ..In the present paper, recent surveillance data on invasive meningococcal disease across Canada are summarized...
  15. pmc Factors influencing childhood influenza immunization
    Vincent J Grant
    Department of Pediatrics, Children s Hospital of Eastern Ontario and the University of Ottawa, Ottawa, Ont
    CMAJ 168:39-41. 2003
    ..7, 95% confidence interval [CI] 1.8-12.6). Children of parents who discussed immunization with a physician were more likely to be immunized than those who had not discussed immunization with a physician (OR 6.8, 95% CI 2.4-19.2)...
  16. pmc Characteristics and outcome of infants with candiduria in neonatal intensive care - a Paediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study
    Joan L Robinson
    Department of Pediatrics, Alberta Children s Hospital Calgary, Alberta, Canada
    BMC Infect Dis 9:183. 2009
    ..There is limited information in the literature on the presentation and prognosis of candidal urinary tract infection (UTI) in infants in the neonatal intensive care unit (NICU)...
  17. ncbi request reprint Maternal respiratory syncytial virus antibody titers: season and children matter
    Nicole Le Saux
    Division of Infectious Diseases, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 22:563-4. 2003
    ..Mean antibody titers were significantly higher between April and September and significantly higher in women who already had children at home...
  18. pmc Community-acquired lobar pneumonia in children in the era of universal 7-valent pneumococcal vaccination: a review of clinical presentations and antimicrobial treatment from a Canadian pediatric hospital
    Anne Rowan-Legg
    Department of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Canada
    BMC Pediatr 12:133. 2012
    ....
  19. doi request reprint Miller Fisher syndrome in a toddler with influenza A (pH1N1) infection
    Cecilia T Costiniuk
    University of Ottawa, Faculty of Medicine, Division of Infectious Diseases, Ottawa, Ontario, Canada
    J Child Neurol 26:385-8. 2011
    ..During pandemics, one may expect to see an increased incidence of uncommon neurologic complications of influenza...
  20. ncbi request reprint A Comparison of group A Streptococcus versus Streptococcus pneumoniae pneumonia
    Nawal Al-Kaabi
    Chalmers Research Group, Statistical Division, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Infect Dis J 25:1008-12. 2006
    ..St reptococcus pyogenes is an uncommon cause of community-acquired pneumonia in children. Further, its clinical course in comparison to pneumonia caused by Streptococcus pneumonia has not been previously highlighted...
  21. pmc A systematic review of the effectiveness of antimicrobial rinse-free hand sanitizers for prevention of illness-related absenteeism in elementary school children
    Emily Meadows
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    BMC Public Health 4:50. 2004
    ..Currently, alternative hand hygiene techniques are being considered, and one such technique is the use of antimicrobial rinse-free hand sanitizers...
  22. ncbi request reprint Fifteen-year-old girl with fever, headache and vomiting
    Rebecca Sherlock
    Department of Paediatrics, Infectious Disease, The Children s Hospital of Eastern Ontario, Ottawa, Canada
    Pediatr Infect Dis J 21:439, 449-50. 2002
  23. doi request reprint Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient data
    Laura Koopman
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Arch Otolaryngol Head Neck Surg 134:128-32. 2008
    ..To determine predictors of the development of asymptomatic middle ear effusion (MEE) in children with acute otitis media (AOM) and to assess the effect of antibiotic therapy in preventing the development of MEE in these children...
  24. ncbi request reprint Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient data
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Pediatrics 119:579-85. 2007
    ..The goal was to determine the predictors of a prolonged course for children with acute otitis media...
  25. ncbi request reprint The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation
    Barbara J Law
    Department of Pediatrics and Child Health, University of Manitoba and the Winnipeg Health Sciences Center, Winnipeg, Canada
    Pediatr Infect Dis J 23:806-14. 2004
    ..This study sought to identify independent risk factors for hospitalization for RSV infection...
  26. ncbi request reprint Lack of evidence of encephalopathy related to pertussis vaccine: active surveillance by IMPACT, Canada, 1993-2002
    Dorothy L Moore
    Montreal Children s Hospital, McGill University Health Centre, Quebec, Canada
    Pediatr Infect Dis J 23:568-71. 2004
    ..Seven cases of encephalopathy began within 7 days after pertussis vaccination, but a more likely cause was found in each instance. No attributable case followed administration of >6.5 million doses of vaccine...
  27. ncbi request reprint Surveillance for influenza admissions among children hospitalized in Canadian immunization monitoring program active centers, 2003-2004
    Dorothy L Moore
    Infectious Diseases Division, Montreal Children s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Pediatrics 118:e610-9. 2006
    ....