Research Topics
| Donna L JohnstonSummaryAffiliation: Children's Hospital of Eastern Ontario Country: Canada Publications
| Collaborators
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Detail Information
Publications
Palliative care consultation in pediatric oncologyDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8 L1, Canada
Support Care Cancer 20:799-803. 2012..Pediatric oncology patients benefit from the involvement of palliative care. This study examined the timing of palliative care consultation...
Superior outcome of pediatric acute myeloid leukemia patients with orbital and CNS myeloid sarcoma: a report from the Children's Oncology GroupDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
Pediatr Blood Cancer 58:519-24. 2012..Extramedullary leukemia (EML) is common in pediatric acute myeloid leukemia (AML) and occurs as leukemia cells within the cerebrospinal fluid (CSF) or as a solid tumor (myeloid sarcoma-MS). The effect of MS on survival is unknown...- Medulloblastoma in children under the age of three years: a retrospective Canadian reviewDonna L Johnston
Division of Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa K1H 8L1, Ontario, Canada
J Neurooncol 94:51-6. 2009.... - Availability and use of palliative care and end-of-life services for pediatric oncology patientsDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON K1H 8L1, Canada
J Clin Oncol 26:4646-50. 2008..We sought to investigate the current practices and resources surrounding palliative and end-of-life care among participating institutions of the Children's Oncology Group (COG)... - Patterns of enrollment of infants with central nervous system tumours on cooperative group studies: a report from the Canadian Pediatric Brain Tumour ConsortiumDonna L Johnston
Division of Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
J Neurooncol 99:243-9. 2010..There needs to be improved availability of clinical trials for these patients so that novel therapies can be evaluated and survival improved... - Fatal neurotoxicity in a patient with down syndrome treated with chemotherapy, irradiation, stem cell transplant, and clofarabineDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario K1H8L1, Canada
J Pediatr Hematol Oncol 32:e111-3. 2010..After her third course, she had a stroke that was felt to be secondary to dehydration and radiation vasculitis. After her subsequent course of clofarabine, she developed fatal neurotoxicity... - The presence of central nervous system disease at diagnosis in pediatric acute myeloid leukemia does not affect survival: a Children's Oncology Group studyDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
Pediatr Blood Cancer 55:414-20. 2010..The presence of central nervous system (CNS) disease in pediatric acute myeloid leukemia (AML) is often thought to confer a worse prognosis. This study examined the outcome of children with AML who had CNS disease at diagnosis... 
Bilateral adrenal neuroblastoma: stage V diseaseDonna L Johnston
Division of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
J Pediatr Hematol Oncol 29:652-5. 2007..We present a case of bilateral adrenal neuroblastoma in an 8-year-old child. This is the first report of bilateral disease in a child over the age of 1 year with stage IV neuroblastoma...- Supratentorial primitive neuroectodermal tumors: a Canadian pediatric brain tumor consortium reportDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada, K1H 8L1
J Neurooncol 86:101-8. 2008..5% of childhood brain tumors. The purpose of this study was to describe the range of treatment regimens used to treat pediatric SPNET in Canada and to identify prognostic factors for overall survival in this population... - Risk factors and therapy for isolated central nervous system relapse of pediatric acute myeloid leukemiaDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
J Clin Oncol 23:9172-8. 2005..CNS relapse of pediatric acute myeloid leukemia (AML) is an infrequent occurrence. This review examines the risk factors and therapy used for patients with an isolated CNS relapse... - Complementary and alternative medicine in pediatric oncology: availability and institutional policies in Canada--a report from the Children's Oncology GroupDonna L Johnston
Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
Pediatr Blood Cancer 47:955-8. 2006..Despite published widespread use of CAM therapies, our study demonstrates that institutional CAM resources and policies on CAM are present in much lower proportions... - Progenitor cell involvement is predictive of response to induction chemotherapy in paediatric acute myeloid leukaemiaDonna L Johnston
Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Br J Haematol 123:431-5. 2003..However, five of six evaluable patients with colonies negative for monosomy 7 entered remission. These data support the hypothesis that leukaemic involvement of early progenitor cells affects the response to induction chemotherapy... - Spinal cord tumors in children under the age of 3 years: a retrospective Canadian reviewShayna Zelcer
Division of Oncology, Children s Hospital, London Health Sciences Center, London, Ontario, N6C 2V5, Canada
Childs Nerv Syst 27:1089-94. 2011..The objectives of our study were to describe the demographic characteristics of spinal cord tumors (SCT) in children less than 3 years of age at diagnosis and to review their treatment and outcome... - Carboplatin hypersensitivity reaction in pediatric patients with low-grade glioma: a Canadian Pediatric Brain Tumor Consortium experienceLucie Lafay-Cousin
Pediatric Brain Tumor Program, Hospital for Sick Children, Toronto, Ontario, Canada
Cancer 112:892-9. 2008..Carboplatin-based regimens have demonstrated activity in pediatric patients with low-grade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy... - A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem gliomaJulia R Sharp
Department of Paediatrics Division of Haematology Oncology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
Eur J Cancer 46:3271-9. 2010..This study aimed to evaluate the safety and efficacy of this regimen in paediatric DIBSG patients... - Pandemic (H1N1) 2009 influenza in Canadian pediatric cancer and hematopoietic stem cell transplant patientsDat Tran
Division of Infectious Diseases, The Hospital for Sick Children, Toronto, ON, Canada
Influenza Other Respi Viruses 6:e105-13. 2012..The impact of pandemic H1N1 influenza (pH1N1) virus in pediatric cancer is uncertain. The objectives of this study were to characterize the clinical course of pH1N1 and identify factors associated with severe outcomes... - Acute encephalopathy and cerebral vasospasm after multiagent chemotherapy including PEG-asparaginase and intrathecal cytarabine for the treatment of acute lymphoblastic leukemiaCatherine M Pound
Department of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
J Pediatr Hematol Oncol 29:183-6. 2007..Neurologic status returned to baseline within 10 days of the acute event, and magnetic resonance angiography findings returned to normal 4 months later... - A case of Moyamoya syndrome and hemoglobin E/beta-thalassemiaTorrey M Parker
Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Pediatr Blood Cancer 52:422-4. 2009..The link between Moyamoya syndrome and HbE/beta-thalassemia may be multifactorial, but Moyamoya syndrome is an important consequence to consider in children with HbE/beta-thalassemia... - HLA-DR(negative), CD34(negative) hypergranular acute myeloid leukemia with trisomy 6 and del(5)(q22q33): case report and review of the literatureBob Argiropoulos
Department of Genetics, Cytogenetics Laboratory, Children s Hospital of Eastern Ontario, Ottawa, ON, Canada
J Pediatr Hematol Oncol 33:e289-95. 2011..We present a current review of the literature and summarize the clinical features of 57 cases of trisomy 6 as the primary chromosomal abnormality in hematological disease... - Parental perceptions of being told their child has cancerTorrey M Parker
Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Pediatr Blood Cancer 51:531-4. 2008..The purpose of this study was to assess how well parents recall discussing the diagnosis of cancer and to summarize suggestions for improvement... - The morbidity and mortality of pediatric oncology patients presenting to the intensive care unit with septic shockCatherine M Pound
Department of Pediatrics, Division of General Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
Pediatr Blood Cancer 51:584-8. 2008..Previous studies, although very limited in number, suggest a particularly poor outcome for these patients if admitted to an intensive care unit with septic shock... - Spontaneous remission of myelodysplastic syndrome with monosomy 7 in a young boyTorrey M Parker
University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
Cancer Genet Cytogenet 182:122-5. 2008..Such findings highlight the need to monitor patients closely for evidence of spontaneous remission... - Vascular complications of cranial radiationDaniel L Keene
Department of Pediatrics, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
Childs Nerv Syst 22:547-55. 2006..The purpose of this study was to examine the frequency and risk factors associated with development of cerebral vascular disease in children after cranial radiation... - Late presentation of opsoclonus-myoclonus-ataxia syndrome in a child with stage 4S neuroblastomaLinsey S Mutch
Division of Hematology/Oncology, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario K1H 8L1, Canada
J Pediatr Hematol Oncol 27:341-3. 2005..Further study of unusual cases of OMA in NB may provide better understanding of the syndrome and additional treatment options for these children... - Outcome of secondary high-grade glioma in children previously treated for a malignant condition: a study of the Canadian Pediatric Brain Tumour ConsortiumAnne Sophie Carret
Pediatric Hematology Oncology, The Montreal Children s Hospital McGill University Health Center, Que, Canada
Radiother Oncol 81:33-8. 2006..Reports of secondary high-grade glioma (HGG) in survivors of childhood cancer are scarce. The aim of this study was to review the pattern of diagnosis, the treatment, and outcome of secondary pediatric HGG... - Fatal skin and liver toxicity in a patient treated with clofarabineDonna L Johnston
Pediatr Blood Cancer 50:1082. 2008 - Relapse of Wilms' tumor 13 years after original diagnosisPaul J Gibson
J Pediatr Hematol Oncol 27:293-4. 2005 - Relapse of childhood acute lymphoblastic leukemia in the lacrimal glandDonna L Johnston
Med Pediatr Oncol 40:337-8. 2003