Donna L Johnston

Summary

Affiliation: Children's Hospital of Eastern Ontario
Country: Canada

Publications

  1. doi request reprint Invasive fungal infections in paediatric acute myeloid leukaemia
    D L Johnston
    Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, ON, Canada
    Mycoses 56:482-7. 2013
  2. doi request reprint Palliative care consultation in pediatric oncology
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8 L1, Canada
    Support Care Cancer 20:799-803. 2012
  3. pmc Superior outcome of pediatric acute myeloid leukemia patients with orbital and CNS myeloid sarcoma: a report from the Children's Oncology Group
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 58:519-24. 2012
  4. doi request reprint Availability and use of palliative care and end-of-life services for pediatric oncology patients
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON K1H 8L1, Canada
    J Clin Oncol 26:4646-50. 2008
  5. doi request reprint Patterns of enrollment of infants with central nervous system tumours on cooperative group studies: a report from the Canadian Pediatric Brain Tumour Consortium
    Donna L Johnston
    Division of Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
    J Neurooncol 99:243-9. 2010
  6. doi request reprint Fatal neurotoxicity in a patient with down syndrome treated with chemotherapy, irradiation, stem cell transplant, and clofarabine
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario K1H8L1, Canada
    J Pediatr Hematol Oncol 32:e111-3. 2010
  7. pmc The presence of central nervous system disease at diagnosis in pediatric acute myeloid leukemia does not affect survival: a Children's Oncology Group study
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 55:414-20. 2010
  8. ncbi request reprint Bilateral adrenal neuroblastoma: stage V disease
    Donna L Johnston
    Division of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    J Pediatr Hematol Oncol 29:652-5. 2007
  9. ncbi request reprint Supratentorial primitive neuroectodermal tumors: a Canadian pediatric brain tumor consortium report
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada, K1H 8L1
    J Neurooncol 86:101-8. 2008
  10. doi request reprint Medulloblastoma in children under the age of three years: a retrospective Canadian review
    Donna L Johnston
    Division of Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa K1H 8L1, Ontario, Canada
    J Neurooncol 94:51-6. 2009

Detail Information

Publications32

  1. doi request reprint Invasive fungal infections in paediatric acute myeloid leukaemia
    D L Johnston
    Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, ON, Canada
    Mycoses 56:482-7. 2013
    ..Invasive fungal infections occurred in 12.0% of paediatric AML patients. Risk factors for IFI and IFI-related sepsis were identified. This knowledge may help to consider targeted strategies...
  2. doi request reprint Palliative care consultation in pediatric oncology
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8 L1, Canada
    Support Care Cancer 20:799-803. 2012
    ..Pediatric oncology patients benefit from the involvement of palliative care. This study examined the timing of palliative care consultation...
  3. pmc Superior outcome of pediatric acute myeloid leukemia patients with orbital and CNS myeloid sarcoma: a report from the Children's Oncology Group
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 58:519-24. 2012
    ..Extramedullary leukemia (EML) is common in pediatric acute myeloid leukemia (AML) and occurs as leukemia cells within the cerebrospinal fluid (CSF) or as a solid tumor (myeloid sarcoma-MS). The effect of MS on survival is unknown...
  4. doi request reprint Availability and use of palliative care and end-of-life services for pediatric oncology patients
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON K1H 8L1, Canada
    J Clin Oncol 26:4646-50. 2008
    ..We sought to investigate the current practices and resources surrounding palliative and end-of-life care among participating institutions of the Children's Oncology Group (COG)...
  5. doi request reprint Patterns of enrollment of infants with central nervous system tumours on cooperative group studies: a report from the Canadian Pediatric Brain Tumour Consortium
    Donna L Johnston
    Division of Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
    J Neurooncol 99:243-9. 2010
    ..There needs to be improved availability of clinical trials for these patients so that novel therapies can be evaluated and survival improved...
  6. doi request reprint Fatal neurotoxicity in a patient with down syndrome treated with chemotherapy, irradiation, stem cell transplant, and clofarabine
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario K1H8L1, Canada
    J Pediatr Hematol Oncol 32:e111-3. 2010
    ..After her third course, she had a stroke that was felt to be secondary to dehydration and radiation vasculitis. After her subsequent course of clofarabine, she developed fatal neurotoxicity...
  7. pmc The presence of central nervous system disease at diagnosis in pediatric acute myeloid leukemia does not affect survival: a Children's Oncology Group study
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 55:414-20. 2010
    ..The presence of central nervous system (CNS) disease in pediatric acute myeloid leukemia (AML) is often thought to confer a worse prognosis. This study examined the outcome of children with AML who had CNS disease at diagnosis...
  8. ncbi request reprint Bilateral adrenal neuroblastoma: stage V disease
    Donna L Johnston
    Division of Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    J Pediatr Hematol Oncol 29:652-5. 2007
    ..We present a case of bilateral adrenal neuroblastoma in an 8-year-old child. This is the first report of bilateral disease in a child over the age of 1 year with stage IV neuroblastoma...
  9. ncbi request reprint Supratentorial primitive neuroectodermal tumors: a Canadian pediatric brain tumor consortium report
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada, K1H 8L1
    J Neurooncol 86:101-8. 2008
    ..5% of childhood brain tumors. The purpose of this study was to describe the range of treatment regimens used to treat pediatric SPNET in Canada and to identify prognostic factors for overall survival in this population...
  10. doi request reprint Medulloblastoma in children under the age of three years: a retrospective Canadian review
    Donna L Johnston
    Division of Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa K1H 8L1, Ontario, Canada
    J Neurooncol 94:51-6. 2009
    ....
  11. ncbi request reprint Complementary and alternative medicine in pediatric oncology: availability and institutional policies in Canada--a report from the Children's Oncology Group
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 47:955-8. 2006
    ..Despite published widespread use of CAM therapies, our study demonstrates that institutional CAM resources and policies on CAM are present in much lower proportions...
  12. ncbi request reprint Risk factors and therapy for isolated central nervous system relapse of pediatric acute myeloid leukemia
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    J Clin Oncol 23:9172-8. 2005
    ..CNS relapse of pediatric acute myeloid leukemia (AML) is an infrequent occurrence. This review examines the risk factors and therapy used for patients with an isolated CNS relapse...
  13. ncbi request reprint Progenitor cell involvement is predictive of response to induction chemotherapy in paediatric acute myeloid leukaemia
    Donna L Johnston
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Br J Haematol 123:431-5. 2003
    ..However, five of six evaluable patients with colonies negative for monosomy 7 entered remission. These data support the hypothesis that leukaemic involvement of early progenitor cells affects the response to induction chemotherapy...
  14. ncbi request reprint Carboplatin hypersensitivity reaction in pediatric patients with low-grade glioma: a Canadian Pediatric Brain Tumor Consortium experience
    Lucie Lafay-Cousin
    Pediatric Brain Tumor Program, Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer 112:892-9. 2008
    ..Carboplatin-based regimens have demonstrated activity in pediatric patients with low-grade glioma (LGG). However, carboplatin hypersensitivity reaction (Cb HSR) represents a common and limiting factor for the continuation of therapy...
  15. doi request reprint Spinal cord tumors in children under the age of 3 years: a retrospective Canadian review
    Shayna Zelcer
    Division of Oncology, Children s Hospital, London Health Sciences Center, London, Ontario, N6C 2V5, Canada
    Childs Nerv Syst 27:1089-94. 2011
    ..The objectives of our study were to describe the demographic characteristics of spinal cord tumors (SCT) in children less than 3 years of age at diagnosis and to review their treatment and outcome...
  16. doi request reprint Outcome of pediatric patients with acute myeloid leukemia (AML) and -5/5q- abnormalities from five pediatric AML treatment protocols: a report from the Children's Oncology Group
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Pediatr Blood Cancer 60:2073-8. 2013
    ..However, there are no large studies on outcomes of children with -5/5q- AML. To determine the disease correlates of this group, we retrospectively analyzed cytogenetic data from five studies of childhood AML...
  17. doi request reprint A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma
    Julia R Sharp
    Department of Paediatrics Division of Haematology Oncology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    Eur J Cancer 46:3271-9. 2010
    ..This study aimed to evaluate the safety and efficacy of this regimen in paediatric DIBSG patients...
  18. pmc Reasons for non-completion of health related quality of life evaluations in pediatric acute myeloid leukemia: a report from the Children's Oncology Group
    Donna L Johnston
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    PLoS ONE 8:e74549. 2013
    ..The objective of this study was to describe reasons for failure to provide HRQL assessments during a pediatric acute myeloid leukemia (AML) clinical trial...
  19. doi request reprint Initial development of the Symptom Screening in Pediatrics Tool (SSPedi)
    Deborah Tomlinson
    Child Health Evaluative Sciences, The Hospital for Sick Children, 123 Edward Street, Toronto, ON, M5G 1E2, Canada
    Support Care Cancer 22:71-5. 2014
    ..The objectives of this study were to identify if any of these scales were suitable for use or adaptation as a self-report symptom screening tool, and if not, to begin the process of creating a new tool...
  20. doi request reprint Pandemic (H1N1) 2009 influenza in Canadian pediatric cancer and hematopoietic stem cell transplant patients
    Dat Tran
    Division of Infectious Diseases, The Hospital for Sick Children, Toronto, ON, Canada
    Influenza Other Respir Viruses 6:e105-13. 2012
    ..The impact of pandemic H1N1 influenza (pH1N1) virus in pediatric cancer is uncertain. The objectives of this study were to characterize the clinical course of pH1N1 and identify factors associated with severe outcomes...
  21. ncbi request reprint Acute encephalopathy and cerebral vasospasm after multiagent chemotherapy including PEG-asparaginase and intrathecal cytarabine for the treatment of acute lymphoblastic leukemia
    Catherine M Pound
    Department of Hematology Oncology, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    J Pediatr Hematol Oncol 29:183-6. 2007
    ..Neurologic status returned to baseline within 10 days of the acute event, and magnetic resonance angiography findings returned to normal 4 months later...
  22. doi request reprint A case of Moyamoya syndrome and hemoglobin E/beta-thalassemia
    Torrey M Parker
    Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 52:422-4. 2009
    ..The link between Moyamoya syndrome and HbE/beta-thalassemia may be multifactorial, but Moyamoya syndrome is an important consequence to consider in children with HbE/beta-thalassemia...
  23. doi request reprint HLA-DR(negative), CD34(negative) hypergranular acute myeloid leukemia with trisomy 6 and del(5)(q22q33): case report and review of the literature
    Bob Argiropoulos
    Department of Genetics, Cytogenetics Laboratory, Children s Hospital of Eastern Ontario, Ottawa, ON, Canada
    J Pediatr Hematol Oncol 33:e289-95. 2011
    ..We present a current review of the literature and summarize the clinical features of 57 cases of trisomy 6 as the primary chromosomal abnormality in hematological disease...
  24. doi request reprint The morbidity and mortality of pediatric oncology patients presenting to the intensive care unit with septic shock
    Catherine M Pound
    Department of Pediatrics, Division of General Pediatrics, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 51:584-8. 2008
    ..Previous studies, although very limited in number, suggest a particularly poor outcome for these patients if admitted to an intensive care unit with septic shock...
  25. doi request reprint Spontaneous remission of myelodysplastic syndrome with monosomy 7 in a young boy
    Torrey M Parker
    University of Ottawa, Faculty of Medicine, Ottawa, Ontario, Canada
    Cancer Genet Cytogenet 182:122-5. 2008
    ..Such findings highlight the need to monitor patients closely for evidence of spontaneous remission...
  26. doi request reprint Parental perceptions of being told their child has cancer
    Torrey M Parker
    Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Pediatr Blood Cancer 51:531-4. 2008
    ..The purpose of this study was to assess how well parents recall discussing the diagnosis of cancer and to summarize suggestions for improvement...
  27. ncbi request reprint Vascular complications of cranial radiation
    Daniel L Keene
    Department of Pediatrics, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
    Childs Nerv Syst 22:547-55. 2006
    ..The purpose of this study was to examine the frequency and risk factors associated with development of cerebral vascular disease in children after cranial radiation...
  28. ncbi request reprint Late presentation of opsoclonus-myoclonus-ataxia syndrome in a child with stage 4S neuroblastoma
    Linsey S Mutch
    Division of Hematology Oncology, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario K1H 8L1, Canada
    J Pediatr Hematol Oncol 27:341-3. 2005
    ..Further study of unusual cases of OMA in NB may provide better understanding of the syndrome and additional treatment options for these children...
  29. ncbi request reprint Outcome of secondary high-grade glioma in children previously treated for a malignant condition: a study of the Canadian Pediatric Brain Tumour Consortium
    Anne Sophie Carret
    Pediatric Hematology Oncology, The Montreal Children s Hospital McGill University Health Center, Que, Canada
    Radiother Oncol 81:33-8. 2006
    ..Reports of secondary high-grade glioma (HGG) in survivors of childhood cancer are scarce. The aim of this study was to review the pattern of diagnosis, the treatment, and outcome of secondary pediatric HGG...
  30. ncbi request reprint Fatal skin and liver toxicity in a patient treated with clofarabine
    Donna L Johnston
    Pediatr Blood Cancer 50:1082. 2008
  31. ncbi request reprint Relapse of Wilms' tumor 13 years after original diagnosis
    Paul J Gibson
    J Pediatr Hematol Oncol 27:293-4. 2005
  32. ncbi request reprint Relapse of childhood acute lymphoblastic leukemia in the lacrimal gland
    Donna L Johnston
    Med Pediatr Oncol 40:337-8. 2003