Jean Louis Chiasson

Summary

Country: Canada

Publications

  1. ncbi Who should benefit from the use of alpha-glucosidase inhibitors?
    Ariane Godbout
    Division of Endocrinology Nutrition and Metabolism, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Curr Diab Rep 7:333-9. 2007
  2. ncbi Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial
    Jean Louis Chiasson
    Research Centre, Centre Hospitalier de l Universite de Montreal, Hotel Dieu, Department of Medicine, University of Montreal, Quebec, Canada
    Lancet 359:2072-7. 2002
  3. ncbi Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial
    Jean Louis Chiasson
    Research Centre, Centre Hospitalier de l Université de Montréal Hôtel Dieu and Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    JAMA 290:486-94. 2003
  4. ncbi Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial
    Jean Louis Chiasson
    Department of Medicine, Université de Montréal and Research Center, Centre Hospitalier de l Universite de Montreal, Quebec, Canada
    Endocr Pract 12:25-30. 2006
  5. ncbi Physical training reverses the increased activity of the hepatic ketone body synthesis pathway in chronically diabetic rats
    Adil El Midaoui
    Diabetes Research Unit, Research Center of Laval University Medical Center, Ste Foy, Quebec, Canada
    Am J Physiol Endocrinol Metab 290:E207-12. 2006
  6. ncbi Acarbose in the prevention of cardiovascular disease in subjects with impaired glucose tolerance and type 2 diabetes mellitus
    Sophie Delorme
    Division of Endocrinology Metabolism and Nutrition, Centre Hospitalier de l Universite de Montreal, Quebec, Canada
    Curr Opin Pharmacol 5:184-9. 2005
  7. ncbi Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats
    Adil El Midaoui
    Diabetes Research Unit, Research Center of Laval University Medical Center, Ste Foy, Canada
    Am J Physiol Endocrinol Metab 288:E748-52. 2005
  8. pmc Increased shear rate resistance and fastest kinetics of erythrocyte aggregation in diabetes measured with ultrasound
    Guy Cloutier
    Laboratory of Biorheology and Medical Ultrasonics, Research Center, University of Montreal Hospital, Montreal, Quebec, Canada
    Diabetes Care 31:1400-2. 2008
  9. pmc Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state
    Jean Louis Chiasson
    Division of Endocrinology Metabolism, Centre Hospitalier de l Universite de Montreal, and the Department of Medicine, Universite de Montreal, Montreal, QC
    CMAJ 168:859-66. 2003
  10. ncbi Tissue- and fibre-specific modifications of insulin-signalling molecules in cardiac and skeletal muscle of diabetic rats
    Demiana Ekladous
    Research Centre, Centre Hospitalier de l Université de Montréal Hôtel Dieu and Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    Clin Exp Pharmacol Physiol 35:971-8. 2008

Collaborators

Detail Information

Publications33

  1. ncbi Who should benefit from the use of alpha-glucosidase inhibitors?
    Ariane Godbout
    Division of Endocrinology Nutrition and Metabolism, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Curr Diab Rep 7:333-9. 2007
    ..AGIs should be considered whenever postprandial hyperglycemia is the dominant metabolic abnormality...
  2. ncbi Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial
    Jean Louis Chiasson
    Research Centre, Centre Hospitalier de l Universite de Montreal, Hotel Dieu, Department of Medicine, University of Montreal, Quebec, Canada
    Lancet 359:2072-7. 2002
    ..The worldwide increase in type 2 diabetes mellitus is becoming a major health concern. We aimed to assess the effect of acarbose in preventing or delaying conversion of impaired glucose tolerance to type 2 diabetes...
  3. ncbi Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial
    Jean Louis Chiasson
    Research Centre, Centre Hospitalier de l Université de Montréal Hôtel Dieu and Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    JAMA 290:486-94. 2003
    ..The worldwide explosive increase in type 2 diabetes mellitus and its cardiovascular morbidity are becoming major health concerns...
  4. ncbi Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial
    Jean Louis Chiasson
    Department of Medicine, Université de Montréal and Research Center, Centre Hospitalier de l Universite de Montreal, Quebec, Canada
    Endocr Pract 12:25-30. 2006
    ..To evaluate, in subjects with impaired glucose tolerance (IGT), the effect of acarbose on the incidence of diabetes, hypertension, and cardiovascular disease...
  5. ncbi Physical training reverses the increased activity of the hepatic ketone body synthesis pathway in chronically diabetic rats
    Adil El Midaoui
    Diabetes Research Unit, Research Center of Laval University Medical Center, Ste Foy, Quebec, Canada
    Am J Physiol Endocrinol Metab 290:E207-12. 2006
    ....
  6. ncbi Acarbose in the prevention of cardiovascular disease in subjects with impaired glucose tolerance and type 2 diabetes mellitus
    Sophie Delorme
    Division of Endocrinology Metabolism and Nutrition, Centre Hospitalier de l Universite de Montreal, Quebec, Canada
    Curr Opin Pharmacol 5:184-9. 2005
    ..It is proposed that the mechanism by which acarbose can lower the risk of cardiovascular events is through diminution of oxidative stress induced by postprandial glycemic excursion...
  7. ncbi Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats
    Adil El Midaoui
    Diabetes Research Unit, Research Center of Laval University Medical Center, Ste Foy, Canada
    Am J Physiol Endocrinol Metab 288:E748-52. 2005
    ....
  8. pmc Increased shear rate resistance and fastest kinetics of erythrocyte aggregation in diabetes measured with ultrasound
    Guy Cloutier
    Laboratory of Biorheology and Medical Ultrasonics, Research Center, University of Montreal Hospital, Montreal, Quebec, Canada
    Diabetes Care 31:1400-2. 2008
    ..To measure with ultrasound the increased erythrocyte aggregation (EA) kinetics and adhesion energy between erythrocytes in patients with type 2 diabetes and poor metabolic control...
  9. pmc Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state
    Jean Louis Chiasson
    Division of Endocrinology Metabolism, Centre Hospitalier de l Universite de Montreal, and the Department of Medicine, Universite de Montreal, Montreal, QC
    CMAJ 168:859-66. 2003
    ..The diagnosis is confirmed by the blood pH, serum bicarbonate level and serum osmolality. Treatment consists of adequate correction of the dehydration, hyperglycemia, ketoacidosis and electrolyte deficits...
  10. ncbi Tissue- and fibre-specific modifications of insulin-signalling molecules in cardiac and skeletal muscle of diabetic rats
    Demiana Ekladous
    Research Centre, Centre Hospitalier de l Université de Montréal Hôtel Dieu and Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    Clin Exp Pharmacol Physiol 35:971-8. 2008
    ..4. In conclusion, the results of the present study demonstrate that adaptation to STZ-induced diabetes varies among skeletal muscle fibre types and the heart, emphasizing the complex tissue-specific responses to diabetes...
  11. ncbi Prevention of Type 2 diabetes: fact or fiction?
    Jean Louis Chiasson
    Universite de Montreal, Research Group on Diabetes and Metabolic Regulation Research Centre, CHUM Hotel Dieu, Department of Medicine, Montreal, Canada
    Expert Opin Pharmacother 8:3147-58. 2007
    ..It can be concluded that Type 2 diabetes can be prevented or delayed through lifestyle modifications and/or pharmacologic interventions. This is a fact...
  12. ncbi Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial
    Laura Andrulionyte
    Department of Medicine, University of Kuopio and Kuopio University Hospital, 70210 Kuopio, Finland
    Diabetes 56:1181-6. 2007
    ..7- and 2.7-fold increased risk for diabetes. Our data indicate that SNPs of PPARA increase the risk of type 2 diabetes alone and in combination with the SNPs of other genes acting closely with PPAR-alpha...
  13. ncbi [Screening and prevention of diabetes]
    Jean Louis Chiasson
    Département de Médicine, l Université de Montréal
    Perspect Infirm 4:18-21. 2006
  14. ncbi Increased glucose excursion in cystic fibrosis and its association with a worse clinical status
    Myriam Costa
    Diabetes Research Group, CHUM Research Center Hôtel Dieu, Montreal QC, Canada H2W 1T7
    J Cyst Fibros 6:376-83. 2007
    ..The objectives are to investigate (a) the relative contribution of insulinopenia and insulin resistance (IR) for glucose tolerance and (b) the association between various glucose parameters and CF clinical status...
  15. ncbi Tumor necrosis factor alpha -238G>A genotype alters postprandial plasma levels of free fatty acids in obese individuals with type 2 diabetes mellitus
    Bénédicte Fontaine-Bisson
    Department of Nutritional Sciences, University of Toronto, Toronto, Canada
    Metabolism 56:649-55. 2007
    ..19 +/- 1.24 vs 1.97 +/- 0.90, P = .6). Our findings suggest that the -238G>A and -308G>A polymorphisms of TNF-alpha alter circulating free fatty acids and insulin resistance in obese subjects with type 2 diabetes mellitus...
  16. ncbi The Canadian Trial of Carbohydrates in Diabetes (CCD), a 1-y controlled trial of low-glycemic-index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C-reactive protein
    Thomas M S Wolever
    Department of Nutritional Sciences, University of Toronto, and the Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Am J Clin Nutr 87:114-25. 2008
    ..The optimal source and amount of dietary carbohydrate for managing type 2 diabetes (T2DM) are unknown...
  17. ncbi Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial
    Laura Andrulionyte
    Department of Medicine, University of Kuopio, 70210 Kuopio, Finland
    J Mol Med (Berl) 84:701-8. 2006
    ..Our results suggest that SNPs of HNF4A and their haplotypes predispose to type 2 diabetes mellitus in female subjects of the STOP-NIDDM study population...
  18. ncbi Pharmacological and surgical intervention for the prevention of diabetes
    Jean Louis Chiasson
    Research Group on Diabetes and Metabolic Regulation, Research Center, Centre hospitalier de l Université de Montréal and Department of Medicine, Universite de Montreal, Montreal, Que, Canada
    Nestle Nutr Workshop Ser Clin Perform Programme 11:31-9; discussion 39-42. 2006
    ..With this new information, we need to design new strategies to screen high-risk populations and to implement the new treatments that have proven effective in the prevention of type-2 diabetes...
  19. ncbi Under-utilization of capillary glucose monitoring by type 2 diabetic patients
    Marie Claude Brindisi
    Research Group on Diabetes and Metabolic Regulation, Research Center, Centre Hospitalier de l Universite de Montreal CHUM, Canada
    Diabetes Res Clin Pract 75:123-5. 2007
    ..Furthermore, postprandial plasma glucose (PPG) is an independent risk factor for cardiovascular disease. We have evaluated the frequency of monitoring and the level of PPG in type 2 diabetic patients followed by their family physician...
  20. ncbi Efficacy and safety of inhaled insulin (exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6-month, randomized, comparative trial
    Priscilla A Hollander
    Baylor University Medical Center, Endocrinology Center, 3600 Gaston Ave, Wadley Tower, Dallas, TX 75246, USA
    Diabetes Care 27:2356-62. 2004
    ....
  21. ncbi Effect of acarbose treatment on the risk of silent myocardial infarctions in patients with impaired glucose tolerance: results of the randomised STOP-NIDDM trial electrocardiography substudy
    Uwe Zeymer
    Medizinische Klinik B, Herzzentrum Ludwigshafen, Ludwigshafen, Germany
    Eur J Cardiovasc Prev Rehabil 11:412-5. 2004
    ..In the randomised STOP-NIDDM trial, we could demonstrate that lowering postprandial plasma glucose with acarbose in subjects with impaired oral glucose tolerance could reduce the risk of diabetes...
  22. ncbi Leptin receptor gene variation predicts weight change in subjects with impaired glucose tolerance
    Jelena Zacharova
    Department of Medicine, University of Kuopio, Finland
    Obes Res 13:501-6. 2005
    ..However, this polymorphism was associated with a significant weight change, suggesting that it may potentially modulate the risk for type 2 diabetes...
  23. ncbi The common polymorphisms (single nucleotide polymorphism [SNP] +45 and SNP +276) of the adiponectin gene predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial
    Jelena Zacharova
    Department of Medicine, University of Kuopio, 70210 Kuopio, Finland
    Diabetes 54:893-9. 2005
    ..004). In conclusion, the G-allele of SNP +45 is a predictor for the conversion to type 2 diabetes. Furthermore, the combined effect of SNP +45 and SNP +276 on the development of type 2 diabetes was stronger than that of each SNP alone...
  24. ncbi Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications
    Marion J Franz
    Diabetes Care 26:S51-61. 2003
  25. ncbi Nutrition principles and recommendations in diabetes
    Marion J Franz
    Diabetes Care 27:S36-46. 2004
  26. ncbi Genetic polymorphisms of tumor necrosis factor-alpha modify the association between dietary polyunsaturated fatty acids and fasting HDL-cholesterol and apo A-I concentrations
    Bénédicte Fontaine-Bisson
    Department of Nutritional Sciences and Nutrition, University of Toronto, Toronto, Canada
    Am J Clin Nutr 86:768-74. 2007
    ..Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine that can induce hyperlipidemia and is known to be modulated by dietary PUFAs...
  27. ncbi The TNF-alpha-238G > a single-nucleotide polymorphism protects against memory decline in older adults with type 2 diabetes
    Michael H Chui
    Department of Nutritional Sciences, University of Toronto, Toronto, ON, Canada
    Behav Neurosci 121:619-24. 2007
    ..Therefore, inflammatory mediators may be important modulators of memory function in individuals with T2DM...
  28. ncbi Alpha-glucosidase inhibitors for patients with type 2 diabetes: response to van de Laar et al
    Markolf Hanefeld
    Diabetes Care 28:1840; author reply 1841. 2005
  29. ncbi Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial
    Laura Andrulionyte
    Department of Medicine, University of Kuopio, 70210 Kuopio, Finland
    Diabetes 55:2148-52. 2006
    ..We conclude that SNPs in PPARD modify the conversion from IGT to type 2 diabetes, particularly in combination with the SNPs of PGC-1A and PPARG2...
  30. ncbi Acute hyperglycemia induces a global downregulation of gene expression in adipose tissue and skeletal muscle of healthy subjects
    Emmanuelle Meugnier
    UMR INSERM870 INRA1235, Faculté de Médecine R Laennec, Rue G Paradin, F 69372 Lyon Cedex 08, France
    Diabetes 56:992-9. 2007
    ....
  31. ncbi Chronic exposure to ketone bodies impairs glucose uptake in adult cardiomyocytes in response to insulin but not vanadate: the role of PI3-K
    Amélie Pelletier
    Montreal Diabetes Research Centre, Centre hospitalier de l Université de Montréal CHUM Hôtel Dieu, 3850 St Urbain, Montreal, Que, Canada, H2W 1T7
    Mol Cell Biochem 296:97-108. 2007
    ..Furthermore, vanadate can bypass insulin resistance and stimulate glucose uptake in OHB-treated cardiomyocytes...
  32. ncbi Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications
    Marion J Franz
    Nutrition Concepts by Franz, Inc, Minneapolis, Minnesota 55439, USA
    Diabetes Care 25:148-98. 2002