John S D Chan


Country: Canada


  1. Lo C, Shi Y, Chenier I, Ghosh A, Wu C, Cailhier J, et al. Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic Mice. Diabetes. 2017;66:1964-1978 pubmed publisher
    ..Our results demonstrate that hnRNP F protects kidneys against oxidative stress and nephropathy via stimulation of Sirtuin-1 expression and signaling in diabetes. ..
  2. Lo C, Shi Y, Chang S, Abdo S, Chenier I, Filep J, et al. Overexpression of heterogeneous nuclear ribonucleoprotein F stimulates renal Ace-2 gene expression and prevents TGF-β1-induced kidney injury in a mouse model of diabetes. Diabetologia. 2015;58:2443-54 pubmed publisher
    ..HnRNP F may be a potential target for treating hypertension and renal fibrosis in diabetes. ..