Research Topics
| P TurroneSummaryAffiliation: Centre for Addiction and Mental Health Country: Canada Publications
| Collaborators |
Detail Information
Publications
Estrogen receptor activation and tardive dyskinesiaP Turrone
Institute of Medical Science, University of Toronto, Ontario
Can J Psychiatry 45:288-90. 2000..To undertake a selective review of the epidemiology, etiology, and treatment of tardive dyskinesia (TD), with emphasis on the potential influence of estrogen in its expression...
Elevation of prolactin levels by atypical antipsychoticsPeter Turrone
Department of Psychiatry, University of Toronto, Ont, Canada
Am J Psychiatry 159:133-5. 2002..Atypical antipsychotics are thought not to elevate prolactin levels. The authors examined data suggesting that atypical antipsychotics do elevate prolactin levels but more transiently than typical antipsychotics...
The vacuous chewing movement (VCM) model of tardive dyskinesia revisited: is there a relationship to dopamine D(2) receptor occupancy?Peter Turrone
Institute of Medical Science, University of Toronto, Toronto, Ont, Canada
Neurosci Biobehav Rev 26:361-80. 2002..These findings are consistent with the possibility that total D(2) occupancy, as well as 'transience' of receptor occupation, may be important in the development of late-onset antipsychotic-induced dyskinetic syndromes...
The relationship between dopamine D2 receptor occupancy and the vacuous chewing movement syndrome in ratsPeter Turrone
Centre for Addiction and Mental Health, Schizophrenia and Continuing Care Program, 250 College Street, Room 745, Toronto, Ontario, Canada M5T 1R8
Psychopharmacology (Berl) 165:166-71. 2003..A dose-response relationship between dopamine D(2) occupancy and acute extrapyramidal symptoms (EPS) has been well established. However, the link with the induction of tardive dyskinesia (TD) is less clear...
Differential effects of within-day continuous vs. transient dopamine D2 receptor occupancy in the development of vacuous chewing movements (VCMs) in ratsPeter Turrone
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Neuropsychopharmacology 28:1433-9. 2003..These findings support the contention that D(2) occupancy levels induced by chronic HAL must be high and sustained through the day before significant risk of VCMs, and perhaps also TD, emerges...
Continuous but not intermittent olanzapine infusion induces vacuous chewing movements in ratsPeter Turrone
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Biol Psychiatry 57:406-11. 2005....
