D M Tomkins

Summary

Affiliation: Centre for Addiction and Mental Health
Country: Canada

Publications

  1. ncbi request reprint Effect of 5-HT(1B) receptor ligands on self-administration of ethanol in an operant procedure in rats
    D M Tomkins
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 66:129-36. 2000
  2. pmc Addiction and the brain: the role of neurotransmitters in the cause and treatment of drug dependence
    D M Tomkins
    Centre for Addiction and Mental Health, Toronto, Ont
    CMAJ 164:817-21. 2001
  3. ncbi request reprint An investigation of the role of 5-HT(2C) receptors in modifying ethanol self-administration behaviour
    Denise M Tomkins
    Biobehavioural Pharmacology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 71:735-44. 2002
  4. ncbi request reprint Effect of CYP2D1 inhibition on the behavioural effects of d-amphetamine
    D M Tomkins
    Addiction Research Foundation, Toronto, Ontario, Canada
    Behav Pharmacol 8:223-35. 1997
  5. ncbi request reprint Effect of naltrexone and its derivatives, nalmefene and naltrindole, on conditioned anticipatory behaviour and saccharin intake in rats
    B L Chow
    Biobehavioural Research Department, Addiction Research Foundation, Toronto, Ontario, Canada
    Behav Pharmacol 8:725-35. 1997
  6. ncbi request reprint Motor impairing effects of ethanol and diazepam in rats selectively bred for high and low ethanol consumption in a limited-access paradigm
    Megan J Shram
    Biobehavioural Pharmacology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Alcohol Clin Exp Res 28:1814-21. 2004

Detail Information

Publications6

  1. ncbi request reprint Effect of 5-HT(1B) receptor ligands on self-administration of ethanol in an operant procedure in rats
    D M Tomkins
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 66:129-36. 2000
    ..These data demonstrate that 5-HT(1B) receptor activation suppresses oral ethanol self-administration. These studies provide further evidence that 5-HT(1B) receptors play a modulatory role in ethanol's behavioral effects...
  2. pmc Addiction and the brain: the role of neurotransmitters in the cause and treatment of drug dependence
    D M Tomkins
    Centre for Addiction and Mental Health, Toronto, Ont
    CMAJ 164:817-21. 2001
    ..These advances in our knowledge promise not only to help us identify the underlying cause of drug abuse and dependence, but also to aid the development of effective treatment strategies...
  3. ncbi request reprint An investigation of the role of 5-HT(2C) receptors in modifying ethanol self-administration behaviour
    Denise M Tomkins
    Biobehavioural Pharmacology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 71:735-44. 2002
    ..Furthermore, 5-HT(2C) receptors may exert a tonic control over ethanol self-administration behaviour, since agonist and antagonist administration had opposing effects on this behaviour...
  4. ncbi request reprint Effect of CYP2D1 inhibition on the behavioural effects of d-amphetamine
    D M Tomkins
    Addiction Research Foundation, Toronto, Ontario, Canada
    Behav Pharmacol 8:223-35. 1997
    ..These studies indicate that AMP is responsible for the behavioural effects seen in rats and that a rat phenocopy model of the human CYP2D6 deficiency state can be produced by CYP2D1 inhibitors...
  5. ncbi request reprint Effect of naltrexone and its derivatives, nalmefene and naltrindole, on conditioned anticipatory behaviour and saccharin intake in rats
    B L Chow
    Biobehavioural Research Department, Addiction Research Foundation, Toronto, Ontario, Canada
    Behav Pharmacol 8:725-35. 1997
    ....
  6. ncbi request reprint Motor impairing effects of ethanol and diazepam in rats selectively bred for high and low ethanol consumption in a limited-access paradigm
    Megan J Shram
    Biobehavioural Pharmacology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Alcohol Clin Exp Res 28:1814-21. 2004
    ..The present study investigated ethanol sensitivity in high (HARF) and low (LARF) ethanol-preferring rats selectively bred under limited-access conditions. For comparative purposes, motor impairment induced by diazepam was also examined...