J Tauscher

Summary

Affiliation: Centre for Addiction and Mental Health
Country: Canada

Publications

  1. ncbi request reprint Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET
    J Tauscher
    PET Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Neuropsychopharmacology 24:522-30. 2001
  2. ncbi request reprint Choosing the right dose of antipsychotics in schizophrenia: lessons from neuroimaging studies
    J Tauscher
    Schizophrenia PET program, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    CNS Drugs 15:671-8. 2001
  3. ncbi request reprint A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia
    N P Verhoeff
    PET Centre and Schizophrenia and Continuing Care Division, Clarke Site, Centre for Addiction and Mental Health, University of Toronto, ON, M5T 1R8, Toronto, Canada
    Psychiatry Res 99:123-35. 2000
  4. ncbi request reprint Dopamine depletion results in increased neostriatal D(2), but not D(1), receptor binding in humans
    N P L G Verhoeff
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    Mol Psychiatry 7:233, 322-8. 2002

Detail Information

Publications4

  1. ncbi request reprint Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET
    J Tauscher
    PET Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Neuropsychopharmacology 24:522-30. 2001
    ..Hence, careful age matching may be recommended for future studies using PET and [11C]WAY-100635 to examine 5-HT1A receptors...
  2. ncbi request reprint Choosing the right dose of antipsychotics in schizophrenia: lessons from neuroimaging studies
    J Tauscher
    Schizophrenia PET program, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    CNS Drugs 15:671-8. 2001
    ..This seems to be particularly important in individuals experiencing a first episode of schizophrenia, as they appear to be especially responsive to pharmacotherapy and quite sensitive to adverse effects...
  3. ncbi request reprint A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia
    N P Verhoeff
    PET Centre and Schizophrenia and Continuing Care Division, Clarke Site, Centre for Addiction and Mental Health, University of Toronto, ON, M5T 1R8, Toronto, Canada
    Psychiatry Res 99:123-35. 2000
    ..Thus, in agreement with the previous ROI studies, voxel-by-voxel analysis confirmed the lack of substantial 5-HT(2A)R BP differences between schizophrenic patients and control subjects...
  4. ncbi request reprint Dopamine depletion results in increased neostriatal D(2), but not D(1), receptor binding in humans
    N P L G Verhoeff
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    Mol Psychiatry 7:233, 322-8. 2002
    ..Thus, while DA depletion "uncovers" D(2)receptors, it does not do so for D(1) receptors. The implications of this finding for measuring endogenous DA and its effects on in vivo receptor binding in humans are discussed...