John Strauss

Summary

Affiliation: Centre for Addiction and Mental Health
Country: Canada

Publications

  1. pmc Association study of early-immediate genes in childhood-onset mood disorders and suicide attempt
    John Strauss
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Psychiatry Res 197:49-54. 2012
  2. ncbi request reprint Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample
    J Strauss
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Mol Psychiatry 10:861-7. 2005
  3. pmc No association between oxytocin or prolactin gene variants and childhood-onset mood disorders
    John S Strauss
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Psychoneuroendocrinology 35:1422-8. 2010
  4. pmc Speech recognition software and electronic psychiatric progress notes: physicians' ratings and preferences
    Yaron D Derman
    Information Management Group, Centre for Addiction and Mental Health, 1001 Queen St, West, Toronto, Ontario, M6J 1H4, Canada
    BMC Med Inform Decis Mak 10:44. 2010
  5. doi request reprint Association study of serotonin system genes in childhood-onset mood disorder
    Sajid A Shaikh
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada
    Psychiatr Genet 18:47-52. 2008
  6. pmc Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury
    Krista L Lanctot
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Brain Inj 24:959-69. 2010
  7. doi request reprint Parent of origin effect and differential allelic expression of BDNF Val66Met in suicidal behaviour
    Vincenzo De Luca
    Department of Psychiatry, University of Toronto, Toronto, Canada
    World J Biol Psychiatry 12:42-7. 2011
  8. doi request reprint The brain-derived neurotrophic factor gene in suicidal behaviour: a meta-analysis
    Clement C Zai
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Int J Neuropsychopharmacol 15:1037-42. 2012
  9. doi request reprint Association between the DAOA/G72 gene and bipolar disorder and meta-analyses in bipolar disorder and schizophrenia
    Daniel J Muller
    Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada
    Bipolar Disord 13:198-207. 2011
  10. ncbi request reprint Brain-derived neurotrophic factor (BDNF) gene and rapid-cycling bipolar disorder: family-based association study
    Daniel J Muller
    Neurogenetics Section, Centre for Addiction and Mental Health Department of Psychiatry, University of Toronto, 250 College Street R30, Toronto, Ontario M5T1R8, Canada
    Br J Psychiatry 189:317-23. 2006

Collaborators

Detail Information

Publications24

  1. pmc Association study of early-immediate genes in childhood-onset mood disorders and suicide attempt
    John Strauss
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Psychiatry Res 197:49-54. 2012
    ..A three-way interaction was observed among HOMER1 rs4704560, rs2290639 and NPTX2 rs705318. The associations we describe for HOMER1 and NPTX2 with SA should be considered preliminary until replicated...
  2. ncbi request reprint Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample
    J Strauss
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Mol Psychiatry 10:861-7. 2005
    ..These results provide evidence that BDNF variants affect liability to juvenile-onset mood disorders, supported by data from two independent samples...
  3. pmc No association between oxytocin or prolactin gene variants and childhood-onset mood disorders
    John S Strauss
    Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Psychoneuroendocrinology 35:1422-8. 2010
    ..Our purpose was to determine if single nucleotide polymorphisms (SNPs) at the loci for OXT, PRL and their receptors, OXTR and PRLR, were associated with childhood-onset mood disorders (COMD)...
  4. pmc Speech recognition software and electronic psychiatric progress notes: physicians' ratings and preferences
    Yaron D Derman
    Information Management Group, Centre for Addiction and Mental Health, 1001 Queen St, West, Toronto, Ontario, M6J 1H4, Canada
    BMC Med Inform Decis Mak 10:44. 2010
    ..Our goal was to determine if speech recognition (SR) would ease the creation of electronic progress note (ePN) documents by physicians at our institution...
  5. doi request reprint Association study of serotonin system genes in childhood-onset mood disorder
    Sajid A Shaikh
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada
    Psychiatr Genet 18:47-52. 2008
    ..The serotonin system has been implicated in neuropsychiatric disorders, including mood disorders...
  6. pmc Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury
    Krista L Lanctot
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Brain Inj 24:959-69. 2010
    ..To determine which serotonergic system-related single nucleotide polymorphisms (SNPs) predicted variation in treatment response to citalopram in depression following a traumatic brain injury (TBI)...
  7. doi request reprint Parent of origin effect and differential allelic expression of BDNF Val66Met in suicidal behaviour
    Vincenzo De Luca
    Department of Psychiatry, University of Toronto, Toronto, Canada
    World J Biol Psychiatry 12:42-7. 2011
    ....
  8. doi request reprint The brain-derived neurotrophic factor gene in suicidal behaviour: a meta-analysis
    Clement C Zai
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Int J Neuropsychopharmacol 15:1037-42. 2012
    ..017; fixed-effects model: p=0.008). Taken together, the results from our study suggest that BDNF Val⁶⁶Met is involved in suicidality. Further studies are required to elucidate its role in suicidal behaviour...
  9. doi request reprint Association between the DAOA/G72 gene and bipolar disorder and meta-analyses in bipolar disorder and schizophrenia
    Daniel J Muller
    Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada
    Bipolar Disord 13:198-207. 2011
    ..This study attempts to replicate the DAOA/G72 findings in BD and to conduct subgroup analyses based on the presence or absence of psychotic symptoms...
  10. ncbi request reprint Brain-derived neurotrophic factor (BDNF) gene and rapid-cycling bipolar disorder: family-based association study
    Daniel J Muller
    Neurogenetics Section, Centre for Addiction and Mental Health Department of Psychiatry, University of Toronto, 250 College Street R30, Toronto, Ontario M5T1R8, Canada
    Br J Psychiatry 189:317-23. 2006
    ..We have previously reported the Val66Met and GT(n) repeat polymorphisms of the brain-derived neurotrophic factor (BDNF) gene to be associated with bipolar disorder. However, these findings have not been replicated consistently...
  11. doi request reprint Analysis of BDNF Val66Met allele-specific mRNA levels in bipolar disorder
    Vincenzo De Luca
    Neurogenetics, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Neurosci Lett 441:229-32. 2008
    ..The Val/Met ratio was much lower in the brain vs. B lymphoblasts. These data do not support a role for genomic imprinting as a modifier of the contribution of BDNF gene to risk of susceptibility to BD...
  12. ncbi request reprint Brain-derived neurotrophic factor (BDNF) gene not associated with antidepressant-induced mania
    Gwyneth Zai
    Neurogenetics Section, Centre for Addiction and Mental Health, Clarke Division, University of Toronto, Toronto, Ontario, Canada
    Bipolar Disord 9:521-5. 2007
    ..Moreover, increasing BDNF production might be one of the mechanisms involved in the alleviation of depression and aggravation of mania in antidepressant treatment...
  13. doi request reprint Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs
    Clement C Zai
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8
    Prog Neuropsychopharmacol Biol Psychiatry 34:1412-8. 2010
    ..We did not find a statistically significant association with the other DRD3 and BDNF polymorphisms. Taken together, the results from the present study suggest that BDNF and DRD3 may not be involved in SCZ susceptibility...
  14. doi request reprint Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder
    Matthew Lanktree
    Neurogenetics Section, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 147:945-51. 2008
    ..Further investigations into the pathologic mechanisms of BDNF and LIN-7 in adult ADHD are required...
  15. doi request reprint Association and CpG SNP analysis of HTR4 polymorphisms with suicidal behavior in subjects with schizophrenia
    Gina Polsinelli
    Neurogenetics Section, Centre for Addiction and Mental Health CAMH, Toronto, Canada
    J Neural Transm 120:253-8. 2013
    ..Moreover, although not significant, the CpG SNP potential methylation analysis would be informative for future methylation analysis on this gene...
  16. ncbi request reprint Association Study of GABRG2 Polymorphisms with Suicidal Behaviour in Schizophrenia Patients with Alcohol Use Disorder
    Clement C Zai
    Neurogenetics Section, Neuroscience Research Department, Centre for Addiction and Mental Health, Toronto, Ont, Canada
    Neuropsychobiology 69:154-8. 2014
    ..These results may help in the discovery of novel treatments for alcoholism and/or prevention of suicide. © 2014 S. Karger AG, Basel. ..
  17. doi request reprint Analysis of treatment-resistant schizophrenia and 384 markers from candidate genes
    Celine Teo
    Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Toronto, Canada
    Pharmacogenet Genomics 22:807-11. 2012
    ..However, this phenotype can be assessed retrospectively in cross-sectional studies and these preliminary results point out the importance of choosing alternative phenotypes in psychiatric pharmacogenetics...
  18. doi request reprint The serotonin transporter polymorphisms and major depression following traumatic brain injury
    Florance Chan
    Sunnybrook Health Sciences Centre, Toronto, ON, Canada
    Brain Inj 22:471-9. 2008
    ..The purpose of this study was to examine the role of the serotonin transporter gene polymorphisms on the risk of major depression following traumatic brain injury (TBI)...
  19. ncbi request reprint Association study of a novel functional polymorphism of the serotonin transporter gene in bipolar disorder and suicidal behaviour
    Vincenzo De Luca
    Neurogenetics Section, Clarke Site, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street R 30, Toronto, Ontario, Canada, M5T 1R8, Canada
    Psychopharmacology (Berl) 182:128-31. 2005
    ..84 df=4 P=0.76). These findings suggest that this new polymorphism in the 5-HTT gene may not influence suicidal behaviour in patients with bipolar disorder...
  20. ncbi request reprint Power based association analysis (PBAT) of serotonergic and noradrenergic polymorphisms in bipolar patients with suicidal behaviour
    Vincenzo De Luca
    Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, ON, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 32:197-203. 2008
    ....
  21. pmc Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1
    Wei Xu
    Neurogenetics Section, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health CAMH, R 32, 250 College Street, Toronto, ON M5T 1R8, Canada
    BMC Med Genet 15:2. 2014
    ..Recently, genome-wide association studies (GWAS) for cases versus controls using single nucleotide polymorphism microarray data have shown promising findings for complex neuropsychiatric disorders, including bipolar disorder (BD)...
  22. ncbi request reprint Lack of association between dopamine-β hydroxylase gene and a history of suicide attempt in schizophrenia: comparison of molecular and statistical haplotype analyses
    Aaron S Howe
    aGroup for Suicide Studies, CAMH bNeurogenetics, Centre for Addiction and Mental Health, Toronto, Ontario, Canada cDepartment of General Biology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
    Psychiatr Genet 24:110-5. 2014
    ..Within the genetic association study design, we compared the statistical haplotype phase with the molecular phase produced by the amplicon size analysis...
  23. ncbi request reprint Copy number variant study of bipolar disorder in Canadian and UK populations implicates synaptic genes
    Abdul Noor
    Molecular Neuropsychiatry and Development Lab, Campbell Family Mental Health Research Institute, The Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 165:303-13. 2014
    ..Further, the identification of CNVs at multiple members of the neurexin gene family in BD individuals, supports the role of synaptic disruption in the etiology of BD...
  24. ncbi request reprint Promoter polymorphism of second tryptophan hydroxylase isoform (TPH2) in schizophrenia and suicidality
    Vincenzo De Luca
    Neurogenetics Section, Clarke Site, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, R 30, Toronto, Ontario, Canada M5T 1R8
    Psychiatry Res 134:195-8. 2005
    ..These findings suggest that these 5' marker haplotypes in the TPH2 gene do not influence suicidal behavior in schizophrenia...