Beth A Sproule

Summary

Affiliation: Centre for Addiction and Mental Health
Country: Canada

Publications

  1. ncbi Lithium in bipolar disorder: can drug concentrations predict therapeutic effect?
    Beth Sproule
    Centre for Addiction and Mental Health, Toronto, and Faculty of Pharmacy and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Clin Pharmacokinet 41:639-60. 2002
  2. ncbi Changing patterns in opioid addiction: characterizing users of oxycodone and other opioids
    Beth Sproule
    Centre for Addiction and Mental Health, Toronto, ON
    Can Fam Physician 55:68-9, 69.e1-5. 2009
  3. ncbi Desvenlafaxine succinate for major depressive disorder
    Beth A Sproule
    The Centre for Addiction and Mental Health, University of Toronto, Canada
    Drugs Today (Barc) 44:475-87. 2008
  4. ncbi Are antipsychotic prescribing patterns different in older and younger adults?: a survey of 1357 psychiatric inpatients in Toronto
    Beth A Sproule
    Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 55:248-54. 2010
  5. ncbi Fuzzy pharmacology: theory and applications
    Beth A Sproule
    Centre for Addiction and Mental Health, 33 Russell Street, Ontario, M5S 2S1, Toronto, Canada
    Trends Pharmacol Sci 23:412-7. 2002
  6. ncbi Effects of 2-week treatment with temazepam and diphenhydramine in elderly insomniacs: a randomized, placebo-controlled trial
    Jennifer R Glass
    Faculty of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada
    J Clin Psychopharmacol 28:182-8. 2008
  7. ncbi Toward the development of a Mood Disorders Insight Scale: modification of Birchwood's Psychosis Insight Scale
    Edward D Sturman
    Psychopharmacology Research Program, Sunnybrook and Women's College Health Science Centre, Toronto, Ontario, Canada
    J Affect Disord 77:21-30. 2003
  8. ncbi Exploring the relationship between perceived inter-dose opioid withdrawal and patient characteristics in methadone maintenance treatment
    Alex K Elkader
    Centre for Addiction and Mental Health, 33 Russell St, Toronto, ON, Canada M5S 2S1
    Drug Alcohol Depend 105:209-14. 2009
  9. ncbi Methadone-nicotine interactions in methadone maintenance treatment patients
    Alexander K Elkader
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Clin Psychopharmacol 29:231-8. 2009
  10. ncbi Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects
    Jennifer R Glass
    Division of Clinical Neuroscience, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada M5S 2S1
    J Clin Psychopharmacol 23:260-8. 2003

Collaborators

Detail Information

Publications17

  1. ncbi Lithium in bipolar disorder: can drug concentrations predict therapeutic effect?
    Beth Sproule
    Centre for Addiction and Mental Health, Toronto, and Faculty of Pharmacy and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Clin Pharmacokinet 41:639-60. 2002
    ....
  2. ncbi Changing patterns in opioid addiction: characterizing users of oxycodone and other opioids
    Beth Sproule
    Centre for Addiction and Mental Health, Toronto, ON
    Can Fam Physician 55:68-9, 69.e1-5. 2009
    ....
  3. ncbi Desvenlafaxine succinate for major depressive disorder
    Beth A Sproule
    The Centre for Addiction and Mental Health, University of Toronto, Canada
    Drugs Today (Barc) 44:475-87. 2008
    ..The only identified potential advantage of desvenlafaxine over venlafaxine or other antidepressant agents at this time is the apparently reduced risk for pharmacokinetic drug interactions...
  4. ncbi Are antipsychotic prescribing patterns different in older and younger adults?: a survey of 1357 psychiatric inpatients in Toronto
    Beth A Sproule
    Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 55:248-54. 2010
    ..To compare antipsychotic prescribing patterns in younger (aged 59 years or younger) and older (aged 60 years or older) patients with psychotic or mood disorders...
  5. ncbi Fuzzy pharmacology: theory and applications
    Beth A Sproule
    Centre for Addiction and Mental Health, 33 Russell Street, Ontario, M5S 2S1, Toronto, Canada
    Trends Pharmacol Sci 23:412-7. 2002
    ..Fuzzy pharmacology is an emerging field that, based on these initial explorations, warrants further investigation...
  6. ncbi Effects of 2-week treatment with temazepam and diphenhydramine in elderly insomniacs: a randomized, placebo-controlled trial
    Jennifer R Glass
    Faculty of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada
    J Clin Psychopharmacol 28:182-8. 2008
    ..The choice of agent to use in the elderly must consider these relative benefits and risks...
  7. ncbi Toward the development of a Mood Disorders Insight Scale: modification of Birchwood's Psychosis Insight Scale
    Edward D Sturman
    Psychopharmacology Research Program, Sunnybrook and Women's College Health Science Centre, Toronto, Ontario, Canada
    J Affect Disord 77:21-30. 2003
    ..75, n=45). Validity testing was based mainly on clinician ratings (r=0.49, n=69). CONCLUSION: The new scale shows promise as a quick method for assessing insight in patients with mood disorders...
  8. ncbi Exploring the relationship between perceived inter-dose opioid withdrawal and patient characteristics in methadone maintenance treatment
    Alex K Elkader
    Centre for Addiction and Mental Health, 33 Russell St, Toronto, ON, Canada M5S 2S1
    Drug Alcohol Depend 105:209-14. 2009
    ..Little is known about the relationship between perceived inter-dose opioid withdrawal and patient characteristics in methadone maintenance treatment...
  9. ncbi Methadone-nicotine interactions in methadone maintenance treatment patients
    Alexander K Elkader
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Clin Psychopharmacol 29:231-8. 2009
    ..The overall results may help to explain high smoking rates in the MMT population and may account for reports of increased positive effects of methadone when the drugs are taken together...
  10. ncbi Acute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects
    Jennifer R Glass
    Division of Clinical Neuroscience, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada M5S 2S1
    J Clin Psychopharmacol 23:260-8. 2003
    ..001) but similar to that with 15 mg temazepam (NS). No psychomotor impairment was detected with 50 mg diphenhydramine. Valerian was not different from placebo on any measure of psychomotor performance or sedation...
  11. ncbi Prescription opioid abuse in patients presenting for methadone maintenance treatment
    Bruna Brands
    Centre for Addiction and Mental Health, University of Toronto, 33 Russell St, Toronto, Ont, Canada M5S 2S1
    Drug Alcohol Depend 73:199-207. 2004
    ..Further research is required to better elucidate the complex relationships between pain, mental health and addiction in order to develop optimal prevention and treatment strategies for prescription opioid dependence...
  12. ncbi The impact of benzodiazepine use on methadone maintenance treatment outcomes
    Bruna Brands
    Centre for Addiction and Mental Health, Toronto, Canada
    J Addict Dis 27:37-48. 2008
    ..Only ongoing cocaine use was negatively related to retention. Benzodiazepine use by methadone maintenance treatment patients is associated with a more complex clinical picture and may negatively influence treatment outcomes...
  13. ncbi Dose-related pharmacokinetics and pharmacodynamics of valproate in the elderly
    Susy Felix
    Psychopharmacology Research Program, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario
    J Clin Psychopharmacol 23:471-8. 2003
    ..Drug-induced CNS effects and nausea severity scores correlated with total and unbound serum valproate concentrations. Significant dose-dependent changes in valproate pharmacokinetics were observed in the elderly...
  14. ncbi Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits
    Jennifer Glass
    University of Toronto, Department of Pharmaceutical Sciences, Toronto, ON, Canada M5S 2S2
    BMJ 331:1169. 2005
    ..In people over 60, the benefits of these drugs may not justify the increased risk, particularly if the patient has additional risk factors for cognitive or psychomotor adverse events...
  15. ncbi Pharmacokinetic and pharmacodynamic evaluation of the inhibition of alprazolam by citalopram and fluoxetine
    Judith Hall
    Psychopharmacology Research Program, Sunnybrook and Women's College Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    J Clin Psychopharmacol 23:349-57. 2003
    ..Neither selective serotonin reuptake inhibitor significantly affected the pharmacodynamic profile of alprazolam. This experiment suggests differential effects by citalopram and fluoxetine on alprazolam kinetics...
  16. ncbi Community pharmacists' attitudes toward and professional interactions with users of psychiatric medication
    Vinay Phokeo
    Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Psychiatr Serv 55:1434-6. 2004
    ..Adequate training in mental health may be key in improving the professional interactions of community pharmacists toward patients who use psychiatric medication...
  17. ncbi Buprenorphine: clinical pharmacokinetics in the treatment of opioid dependence
    Alexander Elkader
    Centre for Addiction and Mental Health, Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Clin Pharmacokinet 44:661-80. 2005
    ..The pharmacokinetic and pharmacodynamic properties of buprenorphine allow it to be a feasible option for substitution therapy in the treatment of opioid dependence...