Xingqun Ni

Summary

Affiliation: Centre for Addiction and Mental Health
Country: Canada

Publications

  1. ncbi Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ont M5T 1R8, Canada
    Neurosci Lett 408:214-9. 2006
  2. ncbi Monoamine oxidase a gene is associated with borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychiatr Genet 17:153-7. 2007
  3. ncbi Association between serotonin transporter gene and borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ont, Canada M5T 1R8
    J Psychiatr Res 40:448-53. 2006
  4. ncbi Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response
    Rudi Hwang
    Neurogenetics Section, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada
    J Psychopharmacol 21:718-27. 2007
  5. ncbi Human p53 tumor suppressor gene (TP53) and schizophrenia: case-control and family studies
    Xingqun Ni
    Neuroscience Research Department, Neurogenetics Section, Centre for Addiction and Mental Health, 250 College Street, Toronto, Canada M5T 1R8
    Neurosci Lett 388:173-8. 2005
  6. doi Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health CAMH, 250 College Street, Toronto, Canada M5T1R8
    Prog Neuropsychopharmacol Biol Psychiatry 33:128-33. 2009
  7. ncbi Family-based association study of the serotonin-2A receptor gene (5-HT2A) and bipolar disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada
    Neuromolecular Med 2:251-9. 2002
  8. ncbi Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations
    Rudi Hwang
    Neurogenetics Section, Center for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, Ontario M5T 1R8, Canada
    Psychopharmacology (Berl) 181:179-87. 2005
  9. doi The catechol-O-methyl-transferase gene in tardive dyskinesia
    Clement C Zai
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    World J Biol Psychiatry 11:803-12. 2010
  10. ncbi Linkage disequilibrium between dopamine D1 receptor gene (DRD1) and bipolar disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada
    Biol Psychiatry 52:1144-50. 2002

Collaborators

Detail Information

Publications15

  1. ncbi Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ont M5T 1R8, Canada
    Neurosci Lett 408:214-9. 2006
    ..Our results suggest that the serotonin 2A receptor gene may not play a major role in the aetiology of borderline personality disorder, but may have a role in personality traits...
  2. ncbi Monoamine oxidase a gene is associated with borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychiatr Genet 17:153-7. 2007
    ..As for its role in aggression, impulsivity, suicide and mood liability, monoamine oxidase A can be considered a functional candidate in borderline personality disorder...
  3. ncbi Association between serotonin transporter gene and borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ont, Canada M5T 1R8
    J Psychiatr Res 40:448-53. 2006
    ..Our results suggest that the serotonin transporter gene may play a role in the aetiology of borderline personality disorder...
  4. ncbi Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response
    Rudi Hwang
    Neurogenetics Section, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada
    J Psychopharmacol 21:718-27. 2007
    ..2003), a trend in the same direction was observed as well. Our findings suggest that the rs4532 SNP may have a small effect if any. Further studies in larger, independent samples are required to validate these findings...
  5. ncbi Human p53 tumor suppressor gene (TP53) and schizophrenia: case-control and family studies
    Xingqun Ni
    Neuroscience Research Department, Neurogenetics Section, Centre for Addiction and Mental Health, 250 College Street, Toronto, Canada M5T 1R8
    Neurosci Lett 388:173-8. 2005
    ..017) in Portuguese schizophrenia families. Haplotype analysis also showed a significant association between TP53 and schizophrenia. These results provide further evidence that TP53 may play a role in the pathogenesis of schizophrenia...
  6. doi Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health CAMH, 250 College Street, Toronto, Canada M5T1R8
    Prog Neuropsychopharmacol Biol Psychiatry 33:128-33. 2009
    ..Our study indicates ""that serotonin genes and their interactions may play a role in the susceptibility to borderline personality disorder...
  7. ncbi Family-based association study of the serotonin-2A receptor gene (5-HT2A) and bipolar disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada
    Neuromolecular Med 2:251-9. 2002
    ....
  8. ncbi Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations
    Rudi Hwang
    Neurogenetics Section, Center for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, Ontario M5T 1R8, Canada
    Psychopharmacology (Berl) 181:179-87. 2005
    ..Genetic factors affecting the density and/or function of D(2) receptors may therefore affect AP response...
  9. doi The catechol-O-methyl-transferase gene in tardive dyskinesia
    Clement C Zai
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    World J Biol Psychiatry 11:803-12. 2010
    ..Changes in dopamine neurotransmission have been implicated in the etiology of TD, and catechol-O-methyl-transferase (COMT) is an enzyme that metabolizes dopamine...
  10. ncbi Linkage disequilibrium between dopamine D1 receptor gene (DRD1) and bipolar disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Canada
    Biol Psychiatry 52:1144-50. 2002
    ..Based on the dopamine hypothesis, the dopamine D1 receptor gene (DRD1) is considered to be a good candidate gene for bipolar disorder (BP)...
  11. pmc Connexin 50 gene on human chromosome 1q21 is associated with schizophrenia in matched case control and family-based studies
    Xingqun Ni
    J Med Genet 44:532-6. 2007
    ..The connexin 40 (Cx40) and connexin 50 (Cx50) genes are located on chromosome 1q21.1, a region strongly linked with schizophrenia. These lines of evidence suggest that Cx40 and Cx50 may play a role in schizophrenia...
  12. ncbi Catechol-O-methyltransferase and monoamine oxidase-A polymorphisms and treatment response to typical and atypical neuroleptics
    Karen A Nolan
    J Clin Psychopharmacol 26:338-40. 2006
  13. ncbi Haplotype association study between DRD1 gene and bipolar type I affective disorder in two samples from Canada and Sardinia
    Maria Del Zompo
    Department of Neurosciences B B Brodie, Section of Clinical Pharmacology, Center of Clinical Psychopharmacology, University of Cagliari, Cagliari, Italy
    Am J Med Genet B Neuropsychiatr Genet 144:237-41. 2007
    ..01. The fact that the same haplotype shows a similar trend for association in samples originating from different ethnic backgrounds seems to imply that the -800C/-48G/1403T haplotype may be considered as a risk factor for BP I disorder...
  14. ncbi COMT158 polymorphism and hostility
    Jan Volavka
    Nathan Kline Institute, Orangeburg, New York 10982, USA
    Am J Med Genet B Neuropsychiatr Genet 127:28-9. 2004
    ..The Met-Met homozygotes (N = 7) were found to have significantly higher levels of hostility than the other patients (N = 53). The hypothesis was thus supported. The finding should be replicated in a larger sample...
  15. ncbi Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia
    Robert M Bilder
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
    Biol Psychiatry 52:701-7. 2002
    ....