Jean Addington

Summary

Affiliation: Centre for Addiction and Mental Health
Country: Canada

Publications

  1. ncbi Early intervention for psychosis: who refers?
    Jean Addington
    Schizophr Res 84:176-7. 2006
  2. ncbi Three-year outcome of family work in an early psychosis program
    Jean Addington
    Department of Psychiatry, University of Toronto, Canada M5T 1R8
    Schizophr Res 79:107-16. 2005
  3. doi Early detection of psychosis: finding those at clinical high risk
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Early Interv Psychiatry 2:147-53. 2008
  4. ncbi The course of cognitive functioning in first episode psychosis: changes over time and impact on outcome
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Schizophr Res 78:35-43. 2005
  5. doi The promise of early intervention
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Early Interv Psychiatry 1:294-307. 2007
  6. ncbi Implementing cognitive-behavioural therapy for first-episode psychosis
    Jean Addington
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5S 2S1, Canada
    Br J Psychiatry Suppl 48:s72-6. 2005
  7. ncbi The role of family work in early psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Canada
    Schizophr Res 79:77-83. 2005
  8. pmc Social cognition mediates illness-related and cognitive influences on social function in patients with schizophrenia-spectrum disorders
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    J Psychiatry Neurosci 35:49-54. 2010
  9. ncbi Facial affect recognition: a mediator between cognitive and social functioning in psychosis?
    Jean Addington
    Department of Psychiatry, University of Toronto, Canada
    Schizophr Res 85:142-50. 2006
  10. ncbi Diagnostic stability over one year in first-episode psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Schizophr Res 86:71-5. 2006

Research Grants

  1. Enhancing the Prospective Prediction of Psychosis
    Jean Addington; Fiscal Year: 2007

Detail Information

Publications75

  1. ncbi Early intervention for psychosis: who refers?
    Jean Addington
    Schizophr Res 84:176-7. 2006
  2. ncbi Three-year outcome of family work in an early psychosis program
    Jean Addington
    Department of Psychiatry, University of Toronto, Canada M5T 1R8
    Schizophr Res 79:107-16. 2005
    ..This family intervention embedded within a treatment program proved to be highly acceptable and effective...
  3. doi Early detection of psychosis: finding those at clinical high risk
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Early Interv Psychiatry 2:147-53. 2008
    ..The aim of this paper was to describe the development of a research clinic for individuals who appear to be at risk of developing a psychosis and the process for educating the community and obtaining referrals...
  4. ncbi The course of cognitive functioning in first episode psychosis: changes over time and impact on outcome
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Schizophr Res 78:35-43. 2005
    ..Finally there are implications for improved methodology in the assessment of both cognitive and social functioning...
  5. doi The promise of early intervention
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Early Interv Psychiatry 1:294-307. 2007
    ..However, there are still many unanswered issues which are in developing stages or which require further investigation...
  6. ncbi Implementing cognitive-behavioural therapy for first-episode psychosis
    Jean Addington
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5S 2S1, Canada
    Br J Psychiatry Suppl 48:s72-6. 2005
    ..Guidelines for integrating CBT into an early psychosis service are presented...
  7. ncbi The role of family work in early psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Canada
    Schizophr Res 79:77-83. 2005
    ..Thus, thirdly we will describe a recovery model that has its origins in the Calgary First Episode Program and has since been expanded for use in the First Episode Psychosis Program in Toronto, Canada...
  8. pmc Social cognition mediates illness-related and cognitive influences on social function in patients with schizophrenia-spectrum disorders
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    J Psychiatry Neurosci 35:49-54. 2010
    ..The objective of the current study was to use structural equation modelling to test the hypothesis that the relation between cognitive performance and social function is mediated by patients' social cognitive abilities...
  9. ncbi Facial affect recognition: a mediator between cognitive and social functioning in psychosis?
    Jean Addington
    Department of Psychiatry, University of Toronto, Canada
    Schizophr Res 85:142-50. 2006
    ..This 1-year longitudinal study tested the hypothesis that facial affect recognition mediates the relationship between cognitive and social functioning...
  10. ncbi Diagnostic stability over one year in first-episode psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Schizophr Res 86:71-5. 2006
    ..Schizophrenia can be reliably diagnosed at the initial assessment. There are clinical implications for dealing with the risk of shifting diagnosis for those who present with schizophrenia spectrum and other psychotic disorders...
  11. pmc Facial affect recognition in individuals at clinical high risk for psychosis
    Jean Addington
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada
    Br J Psychiatry 192:67-8. 2008
    ..Deficits in facial affect recognition appear to be present before the onset of psychosis and may be a vulnerability marker...
  12. ncbi Influence of social perception and social knowledge on cognitive and social functioning in early psychosis
    Jean Addington
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada
    Br J Psychiatry 189:373-8. 2006
    ..Social cognition has been implicated in the relationship between cognition and social functioning...
  13. pmc Social functioning in individuals at clinical high risk for psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Schizophr Res 99:119-24. 2008
    ....
  14. pmc North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research
    Jean Addington
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada
    Schizophr Bull 33:665-72. 2007
    ....
  15. ncbi Patterns, predictors and impact of substance use in early psychosis: a longitudinal study
    J Addington
    Department of Psychiatry, University of Toronto, Toronto, ON, Canada
    Acta Psychiatr Scand 115:304-9. 2007
    ..The purpose was to determine the prevalence of substance use and its impact on outcome 3 years after presentation for a first-episode of psychosis...
  16. ncbi The diagnosis and assessment of individuals prodromal for schizophrenic psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    CNS Spectr 9:588-94. 2004
    ..This article reviews and describes measures that are currently being used and further developed in order to determine both the diagnostic criteria for the prodromal state and the severity of these putatively prodromal symptoms...
  17. ncbi Social and cognitive functioning in psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Schizophr Res 99:176-81. 2008
    ..This study supports the association between cognition and social functioning but indicates that this is a function of how social functioning is conceptualized and assessed...
  18. ncbi Patterns of premorbid functioning in first-episode psychosis: initial presentation
    Jean Addington
    Department of Psychiatry, University of Calgary, Calgary, AB, Canada
    Schizophr Res 62:23-30. 2003
    ....
  19. pmc The prodromal stage of psychotic illness: observation, detection or intervention?
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Ont
    J Psychiatry Neurosci 28:93-7. 2003
    ..This article briefly reviews some of the newer developments and concerns in this area of psychosis research...
  20. ncbi Cognitive functioning in first episode psychosis: initial presentation
    Jean Addington
    Department of Psychiatry, University of Calgary, Foothills Hospital, Calgary, Canada
    Schizophr Res 62:59-64. 2003
    ..There was no evidence to support differences in cognition among the different schizophrenia spectrum diagnostic groups...
  21. ncbi Weight gain in first-episode psychosis
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Onatrio
    Can J Psychiatry 48:272-6. 2003
    ..To examine the extent of weight gain in the first year of treatment in an early psychosis program...
  22. ncbi Symptom outcome 1 year after admission to an early psychosis program
    Jean Addington
    Department of Psychiatry, University of Toronto, Toronto, Ontario
    Can J Psychiatry 48:204-7. 2003
    ..To determine the change in positive, negative, and depressive symptoms after 1 year in an early psychosis program...
  23. ncbi The first episode of psychosis: the experience of relatives
    J Addington
    Department of Psychiatry, University of Calgary, Alberta, Canada
    Acta Psychiatr Scand 108:285-9. 2003
    ..The aim was to determine the extent of and the correlates of the distress and impact of care families of patients with first episode psychosis were experiencing when they first came for treatment...
  24. ncbi Suicidal behaviour in early psychosis
    J Addington
    Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Acta Psychiatr Scand 109:116-20. 2004
    ..This was to determine the prevalence of suicidal behaviours prior to and during the first year of treatment in a comprehensive early psychosis program (EPP) and to identify predictors of suicidal behaviour...
  25. ncbi Pathways to care: help seeking behaviour in first episode psychosis
    J Addington
    Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Acta Psychiatr Scand 106:358-64. 2002
    ..To determine the number of attempts it took before patients with a first episode of psychosis received adequate help, the signs or symptoms that led them to seek help and the people from whom they attempted to seek help...
  26. pmc At clinical high risk for psychosis: outcome for nonconverters
    Jean Addington
    Centre for Mental Health Research and Education, University of Calgary, 3280 Hospital Dr, NW, Calgary, Alberta T2N 4Z6
    Am J Psychiatry 168:800-5. 2011
    ..Less is known about the outcome among this group, referred to as false positive individuals...
  27. pmc North American Prodrome Longitudinal Study (NAPLS 2): overview and recruitment
    Jean Addington
    Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Schizophr Res 142:77-82. 2012
    ..This paper describes the overall methodology of the NAPLS-2 project and reports on the ascertainment and demographics at the midway point of the study with (360 CHR) and 180 controls...
  28. doi Negative symptoms in individuals at clinical high risk of psychosis
    Danijela Piskulic
    Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Psychiatry Res 196:220-4. 2012
    ..Thus, early and persistent negative symptoms may represent a vulnerability for risk of developing psychosis...
  29. doi Predictors of disengagement from treatment in an early psychosis program
    Jacqueline Stowkowy
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
    Schizophr Res 136:7-12. 2012
    ..The purpose of this study is to determine the rate of disengagement from a three year FE treatment program and the predictors of disengagement...
  30. ncbi The association of insight with psychotic symptoms, depression, and cognition in early psychosis: a 3-year follow-up
    Huma Saeedi
    Centre for Addiction and Mental Health, Toronto, Canada
    Schizophr Res 89:123-8. 2007
    ..For this group depression may be a significant concern at least upon initial presentation. Those with poor insight have increased symptoms throughout the first three years and possibly poorer cognitive functioning...
  31. ncbi Three-year outcome of treatment in an early psychosis program
    Jean Addington
    Department of Psychiatry, Alberta Centennial Mental Health Research Chair, Calgary, Alberta
    Can J Psychiatry 54:626-30. 2009
    ..Little is known about the follow-up arrangements offered to patients when their time in a FEP comes to an end...
  32. ncbi Outcome of a first episode of psychosis in adolescence: a 2-year follow-up
    Alissa Pencer
    Department of Psychology, University of Calgary, Calgary, Alberta, Canada
    Psychiatry Res 133:35-43. 2005
    ..These adolescents are doing relatively well following their first episode and reinforce the need to address cannabis use as an integral part of a comprehensive treatment program...
  33. pmc The course of cognitive functioning over six months in individuals at clinical high risk for psychosis
    Mariapaola Barbato
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
    Psychiatry Res 206:195-9. 2013
    ..Future longitudinal research should address if further decline takes place during the prodrome or after conversion to psychosis...
  34. pmc Affect recognition in people at clinical high risk of psychosis
    Jean Addington
    Department of Psychiatry, Faculty of Medicine, University of Calgary, Calgary AB, Canada
    Schizophr Res 140:87-92. 2012
    ..While poorer affect recognition may be associated with vulnerability for psychosis, the current results suggest that it may not be a marker of developing a psychotic illness...
  35. ncbi Serum monitoring of antipsychotic drug levels during concomitant administration of sertraline and antipsychotic medication
    Kathleen Pierson
    Department of Psychiatry, University of Calgary, Foothills Hospital, Alberta
    Can J Psychiatry 51:715-8. 2006
    ..To assess whether pharmacokinetic drug interactions occur when sertraline is added to antipsychotic medications...
  36. pmc Early traumatic experiences in those at clinical high risk for psychosis
    Jean Addington
    Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Early Interv Psychiatry 7:300-5. 2013
    ..The purpose of this study was to determine the extent of childhood trauma and bullying in young people at clinical high risk (CHR) of developing psychosis...
  37. doi Symptom remission in first episode patients
    Jean Addington
    Department of Psychiatry, University of Calgary, Calgary, Canada
    Schizophr Res 106:281-5. 2008
    ....
  38. doi Treating young individuals at clinical high risk for psychosis
    Catherine Marshall
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Early Interv Psychiatry 6:60-8. 2012
    ..Few studies have followed those who do not go on to develop a psychotic illness...
  39. doi Outcome after discharge from an early psychosis program
    Jean Addington
    Department of Psychiatry, University of Calgary, Calgary, Canada
    Schizophr Res 106:363-6. 2008
    ..Results were that, although there was no further improvement in positive symptoms, there was continued improvement in social functioning and signs of improvement in negative symptoms...
  40. ncbi Insight in early psychosis: a 1-year follow-up
    Alisa R Mintz
    Department of Psychology, University of Calgary, Calgary, Alberta, Canada
    Schizophr Res 67:213-7. 2004
    ..Insight improved significantly over 12 months, and was negatively correlated with both positive and negative symptoms, and positively correlated with depressive symptoms at admission. There were no associations with cognition...
  41. pmc Substance use and cognition in early psychosis
    Alissa Pencer
    Department of Psychology, University of Calgary, Calgary, Alta
    J Psychiatry Neurosci 28:48-54. 2003
    ..To determine the relation between substance use and cognition in individuals experiencing their first episode of psychosis...
  42. ncbi Substance misuse and cognitive functioning in early psychosis: a 2 year follow-up
    Amanda McCleery
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8
    Schizophr Res 88:187-91. 2006
    ..These same patients demonstrated better performance at follow-up. These results do not provide evidence for a negative impact of substance use on cognition...
  43. ncbi One-year stability of diagnosis in first-episode nonaffective psychosis: influence of sex
    Ana Cristina Chaves
    Department of Psychiatry, University of Toronto, Ontario
    Can J Psychiatry 51:711-4. 2006
    ..To determine whether sex influences the frequency and direction of diagnostic change 1 year after a first episode of nonaffective psychosis...
  44. pmc Assessment of premorbid function in first-episode schizophrenia: modifications to the Premorbid Adjustment Scale
    Sarah Van Mastrigt
    Departments of Psychiatry and Psychology, University of Calgary, Calgary, Alta
    J Psychiatry Neurosci 27:92-101. 2002
    ..Finally, we make recommendations to enhance the use of the PAS when evaluating patients who have experienced their first episode of schizophrenia...
  45. ncbi Family assessment in early psychosis
    Amanda McCleery
    Centre for Addiction and Mental Health, Toronto, Canada
    Psychiatry Res 152:95-102. 2007
    ..Overall, the CBI appeared to be a reliable and valid measure for use with FEP families. This short and easy to score measure may be useful for families of young people presenting with FEP...
  46. ncbi Substance misuse at presentation to an early psychosis program
    Sarah Van Mastrigt
    Dept of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Soc Psychiatry Psychiatr Epidemiol 39:69-72. 2004
    ..The purpose of this study was to examine the prevalence and correlates of substance misuse in individuals with a first episode of psychosis at the time they first present for treatment...
  47. doi Exploring the neural correlates of delusions of reference
    Mahesh Menon
    Department of Psychiatry, University of Toronto, Toronto, Canada
    Biol Psychiatry 70:1127-33. 2011
    ..The cortical midline structures (CMS) and subcortical regions, including the amygdala and striatum, are linked with self-reference in healthy adults. Less is known about the neural substrates of altered self-reference in schizophrenia...
  48. ncbi The association between social anxiety and social functioning in first episode psychosis
    Marcia Voges
    Department of Psychology, University of Calgary, Canada
    Schizophr Res 76:287-92. 2005
    ..D.=27.42). Results were that negative symptoms and negative self-statements, but not social anxiety, were significant predictors of social functioning. This has implications for addressing these negative cognitions in early psychosis...
  49. doi Attribution style as a factor in psychosis and symptom resolution
    Romina Mizrahi
    CAMH, PET Centre, Toronto, Ontario, Canada
    Schizophr Res 104:220-7. 2008
    ....
  50. doi Predictors of a clinical high risk status among individuals with a family history of psychosis
    Jacqueline Stowkowy
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
    Schizophr Res 147:281-6. 2013
    ..This study compared FHR individuals who also met CHR criteria to FHR individuals who did not on various risk factors, psychopathology and functioning...
  51. pmc Social cognition as a mediator between neurocognition and functional outcome in individuals at clinical high risk for psychosis
    Mariapaola Barbato
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada Electronic address
    Schizophr Res 150:542-6. 2013
    ....
  52. pmc Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive task
    Ivonne Suridjan
    PET Centre, Centre for Addiction and Mental Health, Toronto, Ont
    J Psychiatry Neurosci 38:98-106. 2013
    ..Preclinical studies in animal models of psychosis have shown a selective increase of D2 high as the common factor in psychosis, and the D3 receptor has been suggested to be involved in the pathophysiology of schizophrenia...
  53. ncbi Cognitive behavioral therapy in prodromal psychosis
    Jean Addington
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
    Curr Pharm Des 18:558-65. 2012
    ..Relatively few trials have been completed and this paper reviews the existing trials. Implications of these trials for the treatment of this early phase as well as for designing future studies are discussed...
  54. doi Social cognition and negative symptoms in psychosis
    Danijela Piskulic
    Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary AB, Canada
    Psychiatry Res 188:283-5. 2011
    ....
  55. pmc Cognitive functioning in first-episode schizophrenia
    Jean Addington
    Department of Psychiatry, University of Calgary, Calgary, Alta
    J Psychiatry Neurosci 27:188-92. 2002
    ..To compare the cognitive functioning of a sample of patients experiencing their first episode of schizophrenia with that of patients with an established schizophrenia illness...
  56. doi Using the global functioning social and role scales in a first-episode sample
    Danijela Piskulic
    Department of Psychiatry, University of Calgary, Calgary, AB, Canada
    Early Interv Psychiatry 5:219-23. 2011
    ..The purpose of this study was to determine if these measures would be useful in a first episode population...
  57. doi Prediction and prevention of psychosis in youth at clinical high risk
    Jean Addington
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, T2N 4N1, Canada
    Annu Rev Clin Psychol 8:269-89. 2012
    ..Next, treatment studies are reviewed. The review concludes with a framework for future early identification and treatment studies...
  58. doi Increased stress-induced dopamine release in psychosis
    Romina Mizrahi
    Positron Emission Tomography Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada
    Biol Psychiatry 71:561-7. 2012
    ..However, there is no direct evidence that brain dopaminergic response to stress is exaggerated in psychosis...
  59. doi A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis
    Jean Addington
    Department of Psychiatry, University of Calgary, Alberta, Canada
    Schizophr Res 125:54-61. 2011
    ....
  60. doi Cognitive-behavioral therapy for individuals at high risk of developing psychosis
    Jean Addington
    Department of Psychiatry, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N4N1, Canada
    J Clin Psychol 65:879-90. 2009
    ..Cognitive behavioral therapy (CBT) has been tested as a potentially effective intervention in this group. Here, we describe two cases that were treated with CBT...
  61. ncbi Double-blind, placebo-controlled comparison of the efficacy of sertraline as treatment for a major depressive episode in patients with remitted schizophrenia
    Donald Addington
    Departments of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    J Clin Psychopharmacol 22:20-5. 2002
    ..Testing the efficacy of widely accepted but poorly evaluated treatments should be a research priority. Future studies require a larger sample size and longer duration of treatment...
  62. pmc Maladaptive schemas as a mediator between social defeat and positive symptoms in young people at clinical high risk for psychosis
    Jacqueline Stowkowy
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada
    Early Interv Psychiatry 6:87-90. 2012
    ..The aim of this study was to examine whether negative beliefs about the self and others link social defeat to early signs of psychosis...
  63. ncbi Performance measures for early psychosis treatment services
    Donald Addington
    Department of Psychiatry, the University of Calgary in Alberta, Canada
    Psychiatr Serv 56:1570-82. 2005
    ..The requirements of the study were that the processes used to identify measures and gain consensus should be comprehensive, be reproducible, and reflect the perspective of multiple stakeholders in Canada...
  64. doi Youth at ultra high risk for psychosis: using the Revised Network Episode Model to examine pathways to mental health care
    Katherine M Boydell
    Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada
    Early Interv Psychiatry 7:170-86. 2013
    ..Understanding this process and the strategies that support positive early intervention on the part of youth and significant others is critical...
  65. doi Pathways to care for those at clinical high risk of developing psychosis
    Jacqueline Stowkowy
    Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada
    Early Interv Psychiatry 7:80-3. 2013
    ..Understanding the pathways to care is a prerequisite for early detection in first-episode patients with psychosis. Less in known about the pathways to care for individuals at clinical high risk for psychosis...
  66. pmc Biological, life course, and cross-cultural studies all point toward the value of dimensional and developmental ratings in the classification of psychosis
    Rina Dutta
    Division of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, UK
    Schizophr Bull 33:868-76. 2007
    ..However, we will begin by briefly reviewing the recent history of the classification of the psychoses...
  67. ncbi Extracting spurious messages from noise and risk of schizophrenia-spectrum disorders in a prodromal population
    Ralph E Hoffman
    Yale New Haven Psychiatric Hospital, 184 Liberty Street LV108, New Haven, CT 06519, USA
    Br J Psychiatry 191:355-6. 2007
    ..no drug) and length of speech illusion, with the latter strongly predicting subsequent conversion during medication-free intervals but not during olanzapine treatment...
  68. pmc Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America
    Tyrone D Cannon
    Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Los Angeles, CA 90095
    Arch Gen Psychiatry 65:28-37. 2008
    ....
  69. pmc Assessment of social judgments and complex mental states in the early phases of psychosis
    Shannon M Couture
    University of North Carolina at Chapel Hill, Department of Psychology, CB 3270, Davie Hall, Chapel Hill, NC 27599 3270, USA
    Schizophr Res 100:237-41. 2008
    ..Social cognition plays an important role in the functioning of individuals with psychosis. In this study, we explored two areas of social cognition not previously investigated early in the course of psychosis...
  70. ncbi Weight gain in first-episode psychosis over three years
    Jean Addington
    Schizophr Res 86:335-6. 2006
  71. pmc Recruitment and treatment practices for help-seeking "prodromal" patients
    Thomas H McGlashan
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Bull 33:715-26. 2007
    ..References for details are noted...
  72. ncbi Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis
    Thomas H McGlashan
    Department of Psychiatry, Yale University School of Medicine, 301 Cedar St, New Haven, CT 06519, USA
    Am J Psychiatry 163:790-9. 2006
    ..This study assessed the efficacy of olanzapine in delaying or preventing conversion to psychosis and reducing symptoms in people with prodromal symptoms of schizophrenia...
  73. ncbi Clinical trials during the prodromal stage of schizophrenia
    Jean Addington
    Am J Psychiatry 162:1387. 2005
  74. ncbi Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome
    Scott W Woods
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 54:453-64. 2003
    ..The prodromal phase of schizophrenic disorders has been described prospectively. The present study aimed to determine the short-term efficacy and safety of olanzapine treatment of prodromal symptoms compared with placebo...
  75. ncbi Insight, knowledge, and beliefs about illness in first-episode psychosis
    Laura Quillams
    Can J Psychiatry 48:350. 2003

Research Grants1

  1. Enhancing the Prospective Prediction of Psychosis
    Jean Addington; Fiscal Year: 2007
    ..Each site has proven its ability to recruit prodromal patients in a previous collaboration. ..