Affiliation: Cancer Care Ontario
- Phase II study of dexverapamil plus anthracycline in patients with metastatic breast cancer who have progressed on the same anthracycline regimenE Warner
Toronto Sunnybrook Regional Cancer Centre, Ontario, Canada
Clin Cancer Res 4:1451-7. 1998..The intrinsic cardiotoxicity of dexverapamil makes it less suitable for such studies than several other available agents...
- Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancerE Warner
Division of Medical Oncology, Toronto Sunnybrook Regional Cancer Centre, Toronto, ON, Canada
J Natl Cancer Inst 91:1241-7. 1999..We investigated the extent to which these three mutations contribute to breast cancer incidence in the Ashkenazi Jewish population...
- Hereditary breast cancer. Risk assessment of patients with a family history of breast cancerE Warner
Toronto Sunnybrook Regional Cancer Centre
Can Fam Physician 45:104-12. 1999..To assist family physicians in stratifying women with a family history of breast cancer as being at low, moderate, or high risk of hereditary breast cancer (HBC). To present guidelines for managing each of these risk groups...
- Perceptions of Ashkenazi Jewish breast cancer patients on genetic testing for mutations in BRCA1 and BRCA2K A Phillips
Department of Medical Oncology and Haematology, Princess Margaret Hospital, Toronto, Ontario, Canada
Clin Genet 57:376-83. 2000..The focus on altruistic factors and those related to perceived psychological benefits of testing is notable...
- Long-term results of screening with magnetic resonance imaging in women with BRCA mutationsK Passaperuma
Department of Medicine, Division of Medical Oncology, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
Br J Cancer 107:24-30. 2012..We report screening performance, cancer stage, distant recurrence rate, and breast cancer-specific mortality in our screening study...
- Comparison of breast magnetic resonance imaging, mammography, and ultrasound for surveillance of women at high risk for hereditary breast cancerE Warner
Division of Medical Oncology, Department of Medical Biophysics, and Centre for Research in Women s Health, Toronto, Ontario, Canada
J Clin Oncol 19:3524-31. 2001..The purpose of the present study was to compare breast magnetic resonance imaging (MRI) with ultrasound, mammography, and physical examination in women at high risk for hereditary breast cancer...
- Impact of MRI surveillance and breast cancer detection in young women with BRCA mutationsE Warner
Division of Medical Oncology, Department of Medicine, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
Ann Oncol 22:i44-9. 2011..The oncologist should also have a low threshold for referring young women to professionals experienced in navigating young women and their families through the psychosocial trauma of a breast cancer diagnosis...
- Attitudes of Canadian radiation oncologists towards post-lumpectomy radiotherapy for elderly women with stage I hormone-responsive breast cancerE Warner
Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada
Clin Oncol (R Coll Radiol) 22:97-106. 2010....
- Rapid progression of prostate cancer in men with a BRCA2 mutationS A Narod
Women s College Research Institute, 790 Bay Street, 7th Floor, Women s College Hospital, University of Toronto, Toronto, Ontario, Canada
Br J Cancer 99:371-4. 2008..0 years for men with a BRCA1 mutation, and the difference was highly significant (P<0.01). It may be important to develop targeted chemotherapies to treat prostate cancer in men with a BRCA2 mutation...
- Outcomes of surveillance for contralateral breast cancer in patients less than age 60 at the time of initial diagnosisC Weinstock
Division of Medical Oncology, Sunnybrook Health Sciences Center, Toronto, ON
Curr Oncol 19:e160-4. 2012....
- Can breast MRI computer-aided detection (CAD) improve radiologist accuracy for lesions detected at MRI screening and recommended for biopsy in a high-risk population?T Arazi-Kleinman
Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
Clin Radiol 64:1166-74. 2009..To evaluate the sensitivity and specificity of magnetic resonance imaging (MRI) computer-aided detection (CAD) for breast MRI screen-detected lesions recommended for biopsy in a high-risk population...
- Evidence of a founder BRCA1 mutation in ScotlandA Liede
University of Toronto, Breast Cancer Research, Ontario, Canada
Br J Cancer 82:705-11. 2000..Further studies will be necessary to estimate more accurately the population frequency of the BRCA1 2800delAA mutation among unselected cases of breast and ovarian cancer in Scotland and the UK...