William K Evans
Affiliation: Cancer Care Ontario
- Practitioner feedback on lung cancer practice guidelines in OntarioWilliam K Evans
Juravinski Cancer Center, Hamilton Health Sciences, Hamilton, Ontario, Canada
J Thorac Oncol 1:10-8. 2006..In this study, the PF was reviewed to assess the frequency of response to the surveys, the respondents' characteristics, the nature of the feedback, and the intention to adopt the guideline in practice...
- Chemotherapy for relapsed small cell lung cancer: a systematic review and practice guidelineSusanna Cheng
Toronto Sunnybrook Regional Cancer Centre, Toronto, Canada
J Thorac Oncol 2:348-54. 2007..This clinical practice guideline, based on a systematic review, evaluates chemotherapy options for patients with relapsed small cell lung cancer (SCLC)...
- Cost-effectiveness of chemotherapy for nonsmall-cell lung cancerGeorge Dranitsaris
Cancer Care Ontario, Toronto, Canada
Curr Opin Oncol 14:375-83. 2002..This article reviews the pharmacoeconomic literature to provide guidance on the cost-effective use of chemotherapy in the treatment of advanced nonsmall-cell lung cancer...
- Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic reviewRon Feld
Princess Margaret Hospital, Toronto, Ontario, Canada
J Thorac Oncol 1:367-76. 2006..In this systematic review, we evaluated the role of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of patients with advanced NSCLC...
- Postoperative chemotherapy in nonsmall cell lung cancer: a systematic reviewNaveed Alam
Memorial Sloan Kettering Cancer Center, New York, New York, USA
Ann Thorac Surg 81:1926-36. 2006..To date the trials restricted to stage IB or II disease have obtained the greatest survival benefits with postoperative platinum-based chemotherapy. The evidence does not support the use of postoperative radiotherapy with chemotherapy...
- Cancer Care Ontario's New Drug Funding Program: controlled introduction of expensive anticancer drugsWilliam K Evans
Cancer Care Ontario, 620 University Avenue, Toronto, Ontario, Canada M5G 2L7
Chronic Dis Can 23:152-6. 2002..7 million. These intravenous drugs can now be accessed through nine Regional Cancer Centres, the province's only cancer hospital (Princess Margaret Hospital) and 80 community hospitals and will directly benefit more than 8,700 patients...
- Which cancer clinical trials should be considered for economic evaluation? Selection criteria from the National Cancer Institute of Canada's Working Group on Economic AnalysisWilliam K Evans
Cancer Care Ontario, 620 University Avenue, Toronto, Ontario, Canada M5G 2L7
Chronic Dis Can 24:102-7. 2003..These recommendations are currently guiding priority setting with regard to trials for economic evaluation in NCIC trials. Examples of how these recommendations have been applied to actual trials are presented...
- Continental Divide? The attitudes of US and Canadian oncologists on the costs, cost-effectiveness, and health policies associated with new cancer drugsScott R Berry
Sunnybrook Odette Cancer Center, 2075 Bayview Ave, Toronto, Ontario, Canada
J Clin Oncol 28:4149-53. 2010..We compared their attitudes regarding the costs and cost-effectiveness of medications and related health policy...
- Economic analysis of NCIC CTG JBR.10: a randomized trial of adjuvant vinorelbine plus cisplatin compared with observation in early stage non-small-cell lung cancer--a report of the Working Group on Economic Analysis, and the Lung Disease Site Group, NatioRaymond Ng
Department of Hematology and Medical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada
J Clin Oncol 25:2256-61. 2007..This cost-effectiveness analysis of adjuvant chemotherapy from the perspective of Canada's public health care system was undertaken based on the JBR.10 study population...
- Resource utilization and costs during the initial years of lung cancer screening with computed tomography in CanadaSonya Cressman
The Canadian Centre for Applied Research in Cancer Control, and the British Columbia Cancer Agency, Vancouver, British Columbia, Canada The British Columbia Cancer Agency, Vancouver, British Columbia, Canada Brock University, St Catherines, Ontario, Canada Cancer Care Ontario and the Juravinski Cancer Centre, Hamilton, Ontario, Canada University Health Network and Princess Margaret Cancer Centre, Toronto, Ontario, Canada The Canadian Centre for Applied Research in Cancer Control, the British Columbia Cancer Agency and School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada The University of British Columbia School of Population and Public Health, Vancouver, British Columbia, Canada Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada The British Columbia Cancer Agency and The Canadian Centre for Applied Research in Cancer Control and the University of British Columbia, Vancouver, British Columbia, Canada Beatrice Hunter Cancer Research Institute and Dalhousie University, Halifax, Nova Scotia, Canada The Vancouver General Hospital, Vancouver, British Columbia, Canada Fionna Stanley Hospital and Sir Charles Gairdner Hospital, Perth, Western Australia Université Laval, Quebec, Canada Vancouver General Hospital, The University of British Columbia, Vancouver, British Columbia, Canada The Juravinski Cancer Centre and McMaster University, Hamilton
J Thorac Oncol 9:1449-58. 2014..The decision to implement such programs should be informed by data on resource utilization and costs...
- Influence of sex on toxicity and treatment outcome in small-cell lung cancerSimron Singh
Division of Medical Oncology, Department of Medicine, Princess Margaret Hospital, Toronto, Ontario, Canada
J Clin Oncol 23:850-6. 2005..Studies have shown that women with other tumor types experience greater treatment toxicity, but there have been few studies of sex-related toxicity in SCLC...
- Public engagement in setting priorities in health careRebecca A Bruni
University of Toronto Joint Centre for Bioethics, Toronto, Ontario, Canada
CMAJ 179:15-8. 2008
- End-of-life home care utilization and costs in patients with advanced colorectal cancerNicole Mittmann
Health Outcomes and PharmacoEconomic HOPE Research Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Email
J Community Support Oncol 12:92-8. 2014..To determine overall utilization and costs associated with home care services in Ontario, Canada by linking a home care database to a stage IV colorectal cancer cohort...
- Clinical utility of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the staging of patients with potentially resectable esophageal cancerJohn J You
Departments of Medicine, and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Departments of Radiation Oncology and Surgery, University of Toronto, Ontario, Canada Department of Radiology, McMaster University, and Integrated Department of Nuclear Medicine and Molecular Imaging, Hamilton, Ontario, Canada Department of Nuclear Medicine, Lebanon VA Medical Center, Lebanon, Pennsylvania and Department of Oncology, McMaster University, and Juravinski Hospital and Cancer Centre, Hamilton, Ontario, Canada
J Thorac Oncol 8:1563-9. 2013..18)F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) may play an important role in staging patients with potentially resectable esophageal cancer but its impact on clinical management remains unclear...
- Evaluation of diagnostic assessment units in oncology: a systematic reviewAnna Gagliardi
Cancer Care Ontario, 620 University Ave, Toronto, ON M5G 2L7 Canada
J Clin Oncol 22:1126-35. 2004..This systematic review was undertaken to identify clinical and economic evaluations of diagnostic assessment units for cancer; summarize measures used to evaluate such programs; and discuss the strengths and weaknesses of these evaluations...
- Management of unresected stage III non-small cell lung cancer: a systematic reviewGordon Okawara
Juravinski Cancer Centre at Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada
J Thorac Oncol 1:377-93. 2006..To conduct a systematic review to determine the most effective therapy for patients with unresected stage III non-small cell lung cancer...
- Postoperative radiotherapy in stage II or IIIA completely resected non-small cell lung cancer: a systematic review and practice guidelineGordon Okawara
Hamilton Regional Cancer Centre, 699 Concession Street, Hamilton, Ont, Canada L8V 5C2
Lung Cancer 44:1-11. 2004..Recommendations: Postoperative radiation therapy following complete resection of stage II non-small cell lung cancer is not recommended. No definitive recommendation can be made for stage IIIA disease...
- Adjuvant chemotherapy for completely resected non-small cell lung cancer: a systematic reviewNaveed Alam
Peter MacCallum Cancer Center, Melbourne, Australia
Crit Rev Oncol Hematol 58:146-55. 2006..To conduct a systematic review and to evaluate the impact of postoperative adjuvant chemotherapy on the survival of patients with completely resected non-small cell lung cancer...
- Taxanes as first-line therapy for advanced non-small cell lung cancer: a systematic review and practice guidelineQuincy Chu
Department of Medical Oncology, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alt, Canada
Lung Cancer 50:355-74. 2005....
- The role of radiation therapy in malignant pleural mesothelioma: a systematic reviewYee C Ung
Toronto Sunnybrook Regional Cancer Centre, Toronto, ON, Canada
Radiother Oncol 80:13-8. 2006..Radiation therapy may offer patients presenting with malignant pleural mesothelioma (MPM) symptom palliation and improvements in quality of life. This systematic review will address the role of radiation therapy in the management of MPM...
- Treatment of recurrent small cell lung cancerAngela M Davies
University of California at Davis Cancer Center, 4501 X Street, Suite 3016, Sacramento, CA 95817, USA
Hematol Oncol Clin North Am 18:387-416. 2004
- Better knowledge translation for effective cancer control: a priority for actionEva Grunfeld
Cancer Care Nova Scotia, Dalhousie University, 1278 Tower Road, Halifax, Nova Scotia, Canada B3H 2Y9
Cancer Causes Control 15:503-10. 2004..Adding a knowledge translation component to national cancer control programs can help ensure that even small efforts directed at cancer control can have maximum impact...
- Lifetime costs of colon and rectal cancer management in CanadaJean Maroun
Ottawa Regional Cancer Centre, 503 Smyth Road, Ottawa, Ontario, Canada K1H 1C4
Chronic Dis Can 24:91-101. 2003..Similarly, terminal care might be delivered more efficiently in the home environment or in palliative care units...
- Job stress and job satisfaction of cancer care workersEva Grunfeld
Ottawa Regional Cancer Centre, Ottawa Health Research Institute, Ottawa, Ontario Canada K1H 1C4
Psychooncology 14:61-9. 2005..There is an increasing demand for oncology care as a result of a number of trends. In combination with ongoing changes to the health-care system, these trends have an impact on the workplace environment of systemic therapy personnel...
- 18Fluorodeoxyglucose positron emission tomography in the diagnosis and staging of lung cancer: a systematic reviewYee C Ung
Odette Cancer Centre and University of Toronto, Toronto, ON, Canada
J Natl Cancer Inst 99:1753-67. 2007..Further trials are necessary to establish the clinical utility of PET as part of the standard preoperative assessment of early-stage lung cancer...
- Cancer Care Ontario and American Society of Clinical Oncology adjuvant chemotherapy and adjuvant radiation therapy for stages I-IIIA resectable non small-cell lung cancer guidelineKatherine M W Pisters
M D Anderson Cancer Center, Houston, TX, USA
J Clin Oncol 25:5506-18. 2007..To determine the role of adjuvant chemotherapy and radiation therapy in patients with completely resected stage IA-IIIA non-small-cell lung cancer (NSCLC)...
- Practice guideline for the role of combination chemotherapy in the initial management of limited-stage small-cell lung cancerScott A Laurie
Ottowa Regional Cancer Centre, Ottawa, ON, Canada
Lung Cancer 43:223-40. 2004....
- The use of chemotherapy in patients with advanced malignant pleural mesothelioma: a systematic review and practice guidelinePeter Ellis
McMaster University at Hamilton Health Sciences and Juravinski Cancer Centre, Hamilton, Ontario, Canada
J Thorac Oncol 1:591-601. 2006....
- The role of knowledge translation for cancer control in CanadaEva Grunfeld
Cancer Care Nova Scotia, Halifax, Nova Scotia, Canada
Chronic Dis Can 25:1-6. 2004..It is an ideal time for the Canadian Strategy for Cancer Control and other Canadian cancer control initiatives to determine where they will locate knowledge translation in relation to their objectives...
- Surgical management of malignant pleural mesothelioma: a systematic review and evidence summaryDonna E Maziak
University of Ottawa, Ottawa Hospital, General Campus, 501 Smyth Road, Ottawa, Ont, Canada K1H 8L6
Lung Cancer 48:157-69. 2005..External feedback was obtained from Ontario clinicians, and the provincial Lung Cancer Disease Site Group approved the review...
- The impact of practice guidelines and funding policies on the use of new drugs in advanced non-small cell lung cancerGeorge Dranitsaris
Consultant Pharmacist, Cancer Care Ontario, Ontario M5G 2L7, Canada
J Eval Clin Pract 11:350-6. 2005..A provincial drug database was used to determine the impact that these new policies had on the rate of vinorelbine and gemcitabine uptake within the CCO new drug funding programme...
- The role of high-dose-rate brachytherapy in the palliation of symptoms in patients with non-small-cell lung cancer: a systematic reviewYee C Ung
Toronto Sunnybrook Regional Cancer Centre, Toronto, ON, Canada
Brachytherapy 5:189-202. 2006..This review addresses the role of high-dose-rate endobronchial brachytherapy (HDREB) for symptom palliation in patients with non-small-cell lung cancer...
- Photodynamic therapy in nonsmall cell lung cancer: a systematic reviewDonna E Maziak
University of Ottawa, Ottawa Hospital General Campus, Ontario, Canada
Ann Thorac Surg 77:1484-91. 2004..The safety and effectiveness of photodynamic therapy compared with other treatment modalities remains undefined. Serious adverse effects can occur; therefore, the suitability of patients for this treatment should be carefully assessed...