Research Topics
| Sandra Ramirez-ArcosSummaryAffiliation: Canadian Blood Services Country: Canada Publications
| Collaborators
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Detail Information
Publications
Evaluation of the BacT/ALERT 3D system for the implementation of in-house quality control sterility testing at Canadian Blood ServicesCherie Mastronardi
Canadian Blood Services, Ottawa, Ontario, Canada
Clin Chem Lab Med 48:1179-87. 2010..A standardized process will allow CBS to evaluate and compare blood collection and manufacturing practices across the country...
Evaluation of pooled cultures for bacterial detection in whole blood-derived plateletsSandra Ramirez-Arcos
Infectious Diseases and Donor and Transplantation Services, Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 45:1275-9. 2005..In this study, the sensitivity and specificity of BacT/ALERT cultures performed on pools derived from PRP PLTs are reported...
Canadian experience with detection of bacterial contamination in apheresis plateletsSandra Ramirez-Arcos
Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 47:421-9. 2007..In Canada, both blood suppliers, Héma-Québec (HQ) and Canadian Blood Services (CBS), implemented bacterial testing in apheresis platelets (PLTs) with an automated microbial detection system (BacT/ALERT, bioMérieux)...
Evaluation of the sterility testing process of hematopoietic stem cells at Canadian Blood ServicesCherie Mastronardi
From Canadian Blood Services and The Ottawa Hospital, Ottawa, Ontario, Canada
Transfusion 52:1778-84. 2012..This study was conducted to verify the efficacy of this method and to assess the use of the BacT/ALERT aerobic (BPA) and anaerobic (BPN) culture bottles for microbial testing of HSCs...
Bacterial contamination in platelets: incremental improvements drive down but do not eliminate riskCraig Jenkins
Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 51:2555-65. 2011..This system has been validated and implemented and continuous monitoring of culture rates allows gathering of data regarding true and false positives as well as false negatives...
Bacterial screening of outdated buffy coat platelet pools using a culture system and a rapid immunoassaySandra Ramirez-Arcos
Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 51:2566-72. 2011..This study aimed to determine the rate of detection failures during initial platelet (PLT) screening and evaluate the introduction of anaerobic cultures and immunoassay testing to assess the safety of extending PLT storage beyond 5 days...
Validation and implementation of a new hemoglobinometer for donor screening at Canadian Blood ServicesMindy Goldman
Donor and Transplantation Services, Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 52:1607-13. 2012..Hemoglobin (Hgb) determination is an essential part of donor qualification. We assessed and implemented a new spectrophotometer for donor Hgb determination...
Skin disinfection methods: prospective evaluation and postimplementation resultsSandra Ramirez-Arcos
Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 50:59-64. 2010..Optimal skin disinfection ensures blood safety. In this study, efficacies of the two-step skin disinfection methods used at Canadian Blood Services (CBS) and two one-step methods produced by different manufacturers were compared...
Changes in coagulation factor activity and content of di(2-ethylhexyl)phthalate in frozen plasma units during refrigerated storage for up to five days after thawingWilliam P Sheffield
Research and Development and Product and Hospital Services, Canadian Blood Services, Hamilton, Ontario, Canada
Transfusion 52:493-502. 2012..We measured coagulation factor activity and di(2-ethylhexyl)phthalate (DEHP) concentration in frozen plasma (FP) thawed and stored at 1 to 6°C for up to 5 days...
Conservation of dynamic localization among MinD and MinE orthologues: oscillation of Neisseria gonorrhoeae proteins in Escherichia coliSandra Ramirez-Arcos
Department of Biochemistry, Microbiology and Immunology, Ottawa, ON, Canada
Mol Microbiol 46:493-504. 2002..Finally, in round E. coli cells, GFP-MinDNg appeared to move in a plane parallel to completed septa. This pattern of movement is predicted to be similar in gonococcal cells, which also divide in alternating perpendicular planes...
Quantitative PCR for detection and discrimination of the bloodborne pathogen Staphylococcus epidermidis in platelet preparations using divIVA and icaA as target genesCherie Cameron Mastronardi
Canadian Blood Services, 1800 Alta Vista Drive, Ottawa, ON K1G 4J5, Canada
Can J Microbiol 53:1222-31. 2007..The specificity of this assay was confirmed, as other staphylococcal species that were tested with the optimized parameters were not detected. This QPCR assay could be adaptable for the detection of other bloodborne bacterial pathogens...
Assessment of biofilm-forming ability of coagulase-negative staphylococci isolated from contaminated platelet preparations in CanadaCarey Greco
Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 48:969-77. 2008..The most frequently identified contaminant is Staphylococcus epidermidis, which is noted for its ability to maintain chronic hospital-acquired infections by forming biofilms as a chief virulence mechanism...
Staphylococcus epidermidis forms biofilms under simulated platelet storage conditionsCarey Greco
Canadian Blood Services, Ottawa, Ontario, Canada
Transfusion 47:1143-53. 2007..This study aims to establish biofilm formation (BF) as a mode of growth by S. epidermidis in PLT preparations...
