L Busque

Summary

Country: Canada

Publications

  1. pmc Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
    Lambert Busque
    Research Centre, Maisonneuve Rosemont Hospital, Montreal, Quebec, Canada
    Nat Genet 44:1179-81. 2012
  2. doi request reprint Differential expression of SMAD3 transcripts is not regulated by cis-acting genetic elements but has a gender specificity
    L Busque
    Department of Hematology, Hopital Maisonneuve Rosemont, Montreal, Quebec, Canada
    Genes Immun 10:192-6. 2009
  3. doi request reprint Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies
    Lambert Busque
    Research Centre, Maisonneuve Rosemont Hospital, Montreal, QC, Canada
    Blood 113:3472-4. 2009
  4. doi request reprint Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
    L Bernard
    Research Centre, Maisonneuve Rosemont Hospital, Montreal, Quebec, Canada
    Leukemia 23:287-91. 2009
  5. ncbi request reprint Unrelated bone marrow transplantation for leukocyte adhesion deficiency
    N J Farinha
    Division of Hematology Oncology, Hopital Sainte Justine, Montreal, Canada
    Bone Marrow Transplant 30:979-81. 2002

Collaborators

Detail Information

Publications5

  1. pmc Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
    Lambert Busque
    Research Centre, Maisonneuve Rosemont Hospital, Montreal, Quebec, Canada
    Nat Genet 44:1179-81. 2012
    ..TET2 mutations were specific to individuals with clonal hematopoiesis without hematological malignancies and were associated with alterations in DNA methylation...
  2. doi request reprint Differential expression of SMAD3 transcripts is not regulated by cis-acting genetic elements but has a gender specificity
    L Busque
    Department of Hematology, Hopital Maisonneuve Rosemont, Montreal, Quebec, Canada
    Genes Immun 10:192-6. 2009
    ..Of note, part of the variance in SMAD3 expression was gender related as women expressed lower levels of SMAD3 transcripts than men...
  3. doi request reprint Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies
    Lambert Busque
    Research Centre, Maisonneuve Rosemont Hospital, Montreal, QC, Canada
    Blood 113:3472-4. 2009
    ..This confirms that the skewing of XCI ratio seen in blood cells of aging women is a bona fide and robust biologic phenomenon...
  4. doi request reprint Telomere length is severely and similarly reduced in JAK2V617F-positive and -negative myeloproliferative neoplasms
    L Bernard
    Research Centre, Maisonneuve Rosemont Hospital, Montreal, Quebec, Canada
    Leukemia 23:287-91. 2009
    ..527 vs 0.507, P=0.603), suggesting that the yet-to-be-discovered causative mutation(s) impact the mutated stem cell similarly to JAK2V617F, and that TL measurement may prove useful in the diagnostic workup of JAK2V617F-negative MPN...
  5. ncbi request reprint Unrelated bone marrow transplantation for leukocyte adhesion deficiency
    N J Farinha
    Division of Hematology Oncology, Hopital Sainte Justine, Montreal, Canada
    Bone Marrow Transplant 30:979-81. 2002
    ..Two patients are alive, one of them with a decrease in CD11/CD18 expression. Early referral for HLA-matched unrelated BMT is a reasonable option for patients with LAD-I lacking an HLA-matched related donor...