Research Topics
| B R BrodeurSummaryCountry: Canada Publications
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Detail Information
Publications
Identification of group B streptococcal Sip protein, which elicits cross-protective immunityB R Brodeur
Unite de Recherche en Vaccinologie, Centre Hospitalier Universitaire de Quebec, et Université Laval, Ste Foy, Canada G1V 4G2
Infect Immun 68:5610-8. 2000..The data presented in this study suggest that this highly conserved protein induces cross-protective immunity against GBS infections and emphasize its potential as a universal vaccine candidate...
Bactericidal and cross-protective activities of a monoclonal antibody directed against Neisseria meningitidis NspA outer membrane proteinN Cadieux
Unite de Recherche en Vaccinologie, Centre Hospitalier Universitaire de Québec et Université Laval, Ste Foy, Quebec, Canada G1V 4G2
Infect Immun 67:4955-9. 1999..The data presented in this study suggest that antibodies directed against this highly conserved outer membrane protein could protect against meningococcal infections...
Antigenic and molecular conservation of the gonococcal NspA proteinM Plante
Unite de Recherche en Vaccinologie, Centre Hospitalier Universitaire de Québec et Université Laval, Ste Foy, Quebec, Canada G1V 4G2
Infect Immun 67:2855-61. 1999..gonorrhoeae strains tested. Radioimmunobinding assays clearly indicated that the gonococcal NspA protein is exposed at the surface of intact cells...
Candidate Neisseria meningitidis NspA vaccineD Martin
Unite de Recherche en Vaccinologie, Centre Hospitalier Universitaire de Quebec, Pavillon CHUL et Université Laval, Sainte Foy, G1V 4G2, Quebec, Canada
J Biotechnol 83:27-31. 2000..These data are additional proof that the NspA protein is exposed at the surface of intact meningococcal cells, which is an important characteristic for a vaccine candidate...
Highly conserved Neisseria meningitidis surface protein confers protection against experimental infectionD Martin
Unite de Recherche en Vaccinologie, Centre de Recherche en Infectiologie, Centre Hospitalier Universitaire de Quebec, Ste Foy, Canada
J Exp Med 185:1173-83. 1997..The fact that the NspA protein can elicit the production of bactericidal and protective antibodies emphasize its potential as a vaccine candidate...
Localization of surface immunogenic protein on group B streptococcusS Rioux
Unite de Recherche en Vaccinologie, Centre Hospitalier Universitaire de Québec et Université Laval, Ste Foy, Quebec, Canada G1V 4G2
Infect Immun 69:5162-5. 2001..This result confirmed that Sip is exposed at the intact-cell surface, but it also suggests that its distribution is restricted to certain regions of the cell...
Mapping of B-cell epitopes on the outer membrane P2 porin protein of Haemophilus influenzae by using recombinant proteins and synthetic peptidesD Martin
National Laboratory for Immunology, Laboratory Centre for Disease Control, Ottawa, Canada
Infect Immun 59:1457-64. 1991..These epitopes were not present on the surface of intact H. influenzae cells. Thus, four distinct immunogenic and antigenic regions on the P2 protein have been identified...
