D M Skowronski

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. pmc Influenza vaccine effectiveness in the elderly based on administrative databases: change in immunization habit as a marker for bias
    Travis S Hottes
    Epidemiology Services, BC Centre for Disease Control, Vancouver, British Columbia, Canada
    PLoS ONE 6:e22618. 2011
  2. ncbi request reprint Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses
    Danuta M Skowronski
    Communicable Disease Prevention and Control Service, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 9:e92153. 2014
  3. doi request reprint Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 9:e86555. 2014
  4. pmc H3N2v and other influenza epidemic risk based on age-specific estimates of sero-protection and contact network interactions
    Danuta M Skowronski
    Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control, Vancouver, Canada
    PLoS ONE 8:e54015. 2013
  5. doi request reprint Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v)
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Canada
    J Infect Dis 206:1852-61. 2012
  6. doi request reprint A sentinel platform to evaluate influenza vaccine effectiveness and new variant circulation, Canada 2010-2011 season
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Provincial Health Services Authority, Vancouver, Canada
    Clin Infect Dis 55:332-42. 2012
  7. pmc Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance
    Danuta M Skowronski
    Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    PLoS ONE 7:e38929. 2012
  8. pmc Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything
    Jessica M Conway
    Division of Mathematical Modeling, University of British Columbia Centre for Disease Control, 655 West 12th Avenue, V5Z 4R4 Vancouver, British Columbia, Canada
    BMC Public Health 11:932. 2011
  9. doi request reprint The number needed to vaccinate to prevent infant pertussis hospitalization and death through parent cocoon immunization
    Danuta M Skowronski
    Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control BCCDC, Vancouver Canada
    Clin Infect Dis 54:318-27. 2012
  10. ncbi request reprint Potential cost-effectiveness of annual influenza immunization for infants and toddlers: experience from Canada
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC, Canada V5Z 4R4
    Vaccine 24:4222-32. 2006

Detail Information

Publications59

  1. pmc Influenza vaccine effectiveness in the elderly based on administrative databases: change in immunization habit as a marker for bias
    Travis S Hottes
    Epidemiology Services, BC Centre for Disease Control, Vancouver, British Columbia, Canada
    PLoS ONE 6:e22618. 2011
    ..We explore IVE across six more recent influenza seasons, including periods before, during, and after peak activity to identify potential markers for bias...
  2. ncbi request reprint Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses
    Danuta M Skowronski
    Communicable Disease Prevention and Control Service, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 9:e92153. 2014
    ..During the 2012-13 season, however, detailed genotypic and phenotypic characterization shows that low VE was instead related to mutations in the egg-adapted H3N2 vaccine strain rather than antigenic drift in circulating viruses...
  3. doi request reprint Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 9:e86555. 2014
    ..As such, they warrant further in-depth investigation and search for possible mechanistic explanations...
  4. pmc H3N2v and other influenza epidemic risk based on age-specific estimates of sero-protection and contact network interactions
    Danuta M Skowronski
    Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control, Vancouver, Canada
    PLoS ONE 8:e54015. 2013
    ..However risk assessment may change with time and depends crucially upon the validation of epidemiological features of influenza, notably the serologic correlate of protection and R(0)...
  5. doi request reprint Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v)
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Canada
    J Infect Dis 206:1852-61. 2012
    ..We estimate levels of cross-reactive antibody to H3N2v by age and assess whether seasonal trivalent inactivated influenza vaccine (TIV), with or without adjuvant, may increase seroprotection...
  6. doi request reprint A sentinel platform to evaluate influenza vaccine effectiveness and new variant circulation, Canada 2010-2011 season
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Provincial Health Services Authority, Vancouver, Canada
    Clin Infect Dis 55:332-42. 2012
    ..Interim analysis from the community-based sentinel surveillance system showed circulating H3N2 variants and suboptimal vaccine effectiveness (VE), assessed here for the entire season's data set...
  7. pmc Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance
    Danuta M Skowronski
    Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    PLoS ONE 7:e38929. 2012
    ....
  8. pmc Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything
    Jessica M Conway
    Division of Mathematical Modeling, University of British Columbia Centre for Disease Control, 655 West 12th Avenue, V5Z 4R4 Vancouver, British Columbia, Canada
    BMC Public Health 11:932. 2011
    ..We adapted a city-level contact network model to study different campaigns on influenza morbidity and mortality...
  9. doi request reprint The number needed to vaccinate to prevent infant pertussis hospitalization and death through parent cocoon immunization
    Danuta M Skowronski
    Communicable Disease Prevention and Control Services, British Columbia Centre for Disease Control BCCDC, Vancouver Canada
    Clin Infect Dis 54:318-27. 2012
    ..We illustrate the high number needed to vaccinate (NNV) for this program based on recent epidemiologic data from the provinces of Québec and British Columbia (BC), Canada...
  10. ncbi request reprint Potential cost-effectiveness of annual influenza immunization for infants and toddlers: experience from Canada
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC, Canada V5Z 4R4
    Vaccine 24:4222-32. 2006
    ..We assess cost-effectiveness of this program in Canada...
  11. doi request reprint Randomized controlled trial of dose response to influenza vaccine in children aged 6 to 23 months
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Pediatrics 128:e276-89. 2011
    ..We assessed whether 2 full versus 2 half-doses of trivalent inactivated influenza vaccine (TIV) could improve immunogenicity without increasing reactogenicity in infants (aged 6-11 months) and toddlers (aged 12-23 months)...
  12. ncbi request reprint Oculorespiratory syndrome after influenza immunization in children
    Danuta M Skowronski
    Epidemiology Services, UBC Centre for Disease Control, 655 West 12t Avenue, Vancouver, BC, Canada V5Z 4R4
    Pediatr Infect Dis J 24:63-9. 2005
    ..ORS included bilateral red eyes, facial edema or respiratory symptoms beginning within 24 hours of influenza immunization. Few reports involved children. We assessed the rate of ORS in a pediatric cohort...
  13. pmc Effectiveness of AS03 adjuvanted pandemic H1N1 vaccine: case-control evaluation based on sentinel surveillance system in Canada, autumn 2009
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, BC, Canada
    BMJ 342:c7297. 2011
    ..To assess the effectiveness of the pandemic influenza A/H1N1 vaccine used in Canada during autumn 2009...
  14. pmc Immuno-epidemiologic correlates of pandemic H1N1 surveillance observations: higher antibody and lower cell-mediated immune responses with advanced age
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, BC, V5Z 4R4, Canada
    J Infect Dis 203:158-67. 2011
    ..Pandemic H1N1 (pH1N1) surveillance data showed lower attack rates but higher risk of severe outcomes with advanced age. We explored immuno-epidemiologic correlates of surveillance findings including humoral and cell-mediated immunity (CMI)...
  15. pmc Prevalence of seroprotection against the pandemic (H1N1) virus after the 2009 pandemic
    Danuta M Skowronski
    BC Centre for Disease Control, Vancouver, BC
    CMAJ 182:1851-6. 2010
    ..We reassessed this profile of seroprotection by age in the same region six months after the fall 2009 pandemic and vaccination campaign...
  16. ncbi request reprint Estimating vaccine effectiveness against laboratory-confirmed influenza using a sentinel physician network: results from the 2005-2006 season of dual A and B vaccine mismatch in Canada
    D M Skowronski
    Epidemiology Services, BC Centre for Disease Control, Canada
    Vaccine 25:2842-51. 2007
    ....
  17. ncbi request reprint Solicited adverse events after influenza immunization among infants, toddlers, and their household contacts
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Pediatrics 117:1963-71. 2006
    ..We assessed adverse events, including oculorespiratory syndrome, following influenza immunization during the first year of a publicly-funded program for infants, toddlers and their household members in Canada...
  18. pmc Coordinated response to SARS, Vancouver, Canada
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Emerg Infect Dis 12:155-8. 2006
    ..Baseline preparedness for pandemic threats may account for the absence of sustained transmission and fewer cases of SARS in Vancouver...
  19. doi request reprint Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006-2007
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    J Infect Dis 199:168-79. 2009
    ..We describe a sentinel surveillance approach to link influenza variant detection with component-specific vaccine effectiveness (VE) estimation...
  20. doi request reprint Is routine influenza immunization warranted in early pregnancy?
    Danuta M Skowronski
    BC Centre for Disease Control, Vancouver, BC, Canada
    Vaccine 27:4754-70. 2009
    ..Evidence is otherwise insufficient to recommend routine TIV as the standard of practice for all healthy women beginning in early pregnancy...
  21. ncbi request reprint Oculo-respiratory syndrome: a new influenza vaccine-associated adverse event?
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, University of British Columbia, Vancouver, Canada
    Clin Infect Dis 36:705-13. 2003
    ..The surveillance case definition for ORS for 2001-2002 was revised to include onset <or=24 h after vaccination, with no restriction on duration. ORS should be incorporated into annual influenza vaccine safety monitoring...
  22. ncbi request reprint Severe acute respiratory syndrome (SARS): a year in review
    Danuta M Skowronski
    University of British Columbia Center for Disease Control, Vancouver, British Columbia, Canada V5Z 4R4
    Annu Rev Med 56:357-81. 2005
    ..This review synthesizes lessons learned from this remarkable achievement. These lessons can be applied to re-emergence of SARS or to the next pandemic threat to arise...
  23. ncbi request reprint The changing age and seasonal profile of pertussis in Canada
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, Epidemiology Services, Vancouver, British Columbia, Canada V5Z 4R4
    J Infect Dis 185:1448-53. 2002
    ....
  24. pmc Low risk of recurrence of oculorespiratory syndrome following influenza revaccination
    Danuta M Skowronski
    UBC Centre for Disease Control, Vancouver, BC
    CMAJ 167:853-8. 2002
    ..We examined the risk of recurrence of ORS for individuals affected in 2000-2001 who were revaccinated in the community setting in 2001-2002...
  25. ncbi request reprint Carotid artery dissection as a possible severe complication of pertussis in an adult: clinical case report and review
    Danuta M Skowronski
    British Columbia Centre for Disease Control, St Paul s Hospital and University of British Columbia, Vancouver, British Columbia V5Z 4R4, Canada
    Clin Infect Dis 36:e1-4. 2003
    ..Adult booster immunization against pertussis should be considered to protect adults themselves from this illness and its potential complications...
  26. ncbi request reprint Does antigen-specific cytokine response correlate with the experience of oculorespiratory syndrome after influenza vaccine?
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, Epidemiology Services, Vancouver, British Columbia, Canada
    J Infect Dis 187:495-9. 2003
    ..Although vaccinated ORS-affected individuals had less of a type 1 basis than did vaccinated unaffected individuals, this difference was not statistically significant...
  27. pmc Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada
    Danuta M Skowronski
    British Columbia Centre for Disease Control BCCDC, Vancouver, British Columbia, Canada
    PLoS Med 7:e1000258. 2010
    ..Several epidemiologic investigations were conducted through the summer to assess this putative association...
  28. ncbi request reprint Randomized, double-blind, placebo-controlled trial to assess the rate of recurrence of oculorespiratory syndrome following influenza vaccination among persons previously affected
    Danuta M Skowronski
    Canadian Association for Immunization Research and Evaluation, Vancouver, British Columbia, Canada
    Clin Infect Dis 37:1059-66. 2003
    ..Previously affected persons should be informed of the risk of ORS recurrence but also that episodes of such recurrence are mild and well tolerated...
  29. ncbi request reprint Injection-site reactions to booster doses of acellular pertussis vaccine: rate, severity, and anticipated impact
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Pediatrics 112:e453. 2003
    ....
  30. ncbi request reprint Adult tetanus, diphtheria and pertussis immunization: knowledge, beliefs, behavior and anticipated uptake
    Danuta M Skowronski
    University of British Columbia Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC, Canada V5Z 4R4
    Vaccine 23:353-61. 2004
    ..To anticipate adult coverage with a combined product containing tetanus (T) and diphtheria (d) toxoids and acellular pertussis (aP) vaccine as a booster dose, we conducted a survey of households in British Columbia, Canada...
  31. doi request reprint Influenza Β/Victoria antigen induces strong recall of Β/Yamagata but lower Β/Victoria response in children primed with two doses of Β/Yamagata
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Pediatr Infect Dis J 30:833-9. 2011
    ..Trivalent inactivated influenza vaccine (TIV) contains 1 of 2 influenza B/lineages (B/Yamagata or B/Victoria) annually. We assessed prime-boost responses in young children following a change in the B/lineage included in TIV...
  32. pmc Protective measures and human antibody response during an avian influenza H7N3 outbreak in poultry in British Columbia, Canada
    Danuta M Skowronski
    BC Centre for Disease Control, Vancouver, BC
    CMAJ 176:47-53. 2007
    ..In 2004 an outbreak of avian influenza of the H7N3 subtype occurred among poultry in British Columbia, Canada. We report compliance with recommended protective measures and associated human infections during this outbreak...
  33. ncbi request reprint Elimination of acute hepatitis B among adolescents after one decade of an immunization program targeting Grade 6 students
    David M Patrick
    Epidemiology Services, University of British Columbia Centre for Disease Control, Vancouver, Canada
    Pediatr Infect Dis J 22:874-7. 2003
    ..This study documents trends in the reported rate of acute HB disease since 1992 and examines factors bearing on the rate of infection throughout the period of program implementation...
  34. ncbi request reprint Skin testing to evaluate oculo-respiratory syndrome (ORS) associated with influenza vaccination during the 2000-2001 season
    Danuta M Skowronski
    UBC Centre for Disease Control, 655 West 12th Avenue, Vancouver, British Columbia, Canada V5Z 4R4
    Vaccine 20:2713-9. 2002
    ..Skin test reaction size or quality could not identify persons at risk of ORS. Skin testing could not identify a specific strain or the stage in the manufacturing process during which the trigger may have been introduced...
  35. pmc Age-related trends in the timeliness and prediction of medical visits, hospitalizations and deaths due to pneumonia and influenza, British Columbia, Canada, 1998-2004
    R Sebastian
    Epidemiology Services, British Columbia Centre for Disease Control, 655 12th Avenue West, Vancouver, British Columbia, V5Z 4R4 Canada
    Vaccine 26:1397-403. 2008
    ..We conclude that the very young and old suffer the greatest morbidity due to P&I, and an indirect role for school-aged children in anticipating the risk to others warrants further evaluation...
  36. ncbi request reprint Influenza revaccination of elderly travelers: antibody response to single influenza vaccination and revaccination at 12 weeks
    J A Buxton
    British Columbia Centre for Disease Control, University of British Columbia, Vancouver, Canada
    J Infect Dis 184:188-91. 2001
    ..Response to B/Harbin was less throughout the study. A/Sydney antibody titer was lower with more times vaccinated in the previous 5 years. Therefore, a second vaccine did not enhance the immune response...
  37. pmc Novel avian influenza H7N3 strain outbreak, British Columbia
    Martin Hirst
    British Columbia Cancer Agency BCCA Genome Sciences Centre, Vancouver, British Columbia, Canada
    Emerg Infect Dis 10:2192-5. 2004
    ..This insertion likely occurred by recombination between the hemagglutination and matrix genes in the LPAI virus...
  38. pmc Modeling control strategies of respiratory pathogens
    Babak Pourbohloul
    Division of Mathematical Modeling, University of British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Emerg Infect Dis 11:1249-56. 2005
    ..Contact network epidemiology can provide valuable quantitative input to public health decisionmaking, even before a pathogen is well characterized...
  39. pmc Initial human transmission dynamics of the pandemic (H1N1) 2009 virus in North America
    Babak Pourbohloul
    Division of Mathematical Modeling, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Influenza Other Respir Viruses 3:215-22. 2009
    ..We determined the reproduction number of pandemic (H1N1) 2009 by analyzing the dynamics of the complete case series in Mexico City during this early period...
  40. ncbi request reprint A modified vaccine reduces the rate of large injection site reactions to the preschool booster dose of diphtheria-tetanus-acellular pertussis vaccine: results of a randomized, controlled trial
    David W Scheifele
    Canadian Association for Immunization Research and Evaluation CAIRE and the Vaccine Evaluation Center, BC Children s Hospital and the University of British Columbia, Vancouver, British Columbia, Canada
    Pediatr Infect Dis J 24:1059-66. 2005
    ..Large injection site reactions commonly follow booster doses of diphtheria-tetanus-acellular pertussis (DTaP) vaccines at 4-6 years of age. A vaccine with lower diphtheria and pertussis dosage (Tdap) might be better tolerated for this dose...
  41. pmc Human illness from avian influenza H7N3, British Columbia
    S Aleina Tweed
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Emerg Infect Dis 10:2196-9. 2004
    ..Surveillance identified two persons with confirmed avian influenza infection. Symptoms included conjunctivitis and mild influenzalike illness...
  42. doi request reprint Rapid decline of influenza vaccine-induced antibody in the elderly: is it real, or is it relevant?
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    J Infect Dis 197:490-502. 2008
    ..The historic concern that the influenza vaccine-induced antibody response in the elderly declines more rapidly and below seroprotective levels within 4 months of immunization should be reconsidered...
  43. ncbi request reprint One arm or two? Concurrent administration of meningococcal C conjugate and hepatitis B vaccines in pre-teens
    Karen L Pielak
    British Columbia Centre for Disease Control, Vancouver, BC
    Can J Public Health 99:52-6. 2008
    ....
  44. ncbi request reprint Ocular and respiratory symptoms attributable to inactivated split influenza vaccine: evidence from a controlled trial involving adults
    David W Scheifele
    Canadian Association for Immunization Research and Evaluation of Vancouver, British Columbia, Canada
    Clin Infect Dis 36:850-7. 2003
    ..We conclude that certain mild oculorespiratory symptoms were triggered by an influenza vaccine that was otherwise minimally reactogenic and, hence, that such symptoms might be associated with influenza vaccines in general...
  45. ncbi request reprint The Genome sequence of the SARS-associated coronavirus
    Marco A Marra
    British Columbia Cancer Agency BCCA Genome Sciences Centre, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada
    Science 300:1399-404. 2003
    ....
  46. ncbi request reprint Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus
    Raymond H See
    University of British Columbia Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada
    J Gen Virol 87:641-50. 2006
    ..Finally, the sera of vaccinated mice contained antibodies to S, further suggesting a role for this protein in conferring protective immunity against SARS-CoV infection...
  47. ncbi request reprint Disparities in varicella vaccine coverage in the absence of public funding
    Reka Gustafson
    Department of Health Care and Epidemiology, University of British Columbia, 655 West 12th Avenue, Vancouver, BC, Canada V5Z 4R4
    Vaccine 23:3519-25. 2005
    ..Among parents of susceptible children, 59% (343/582) would vaccinate their child if it were provided free; 25% (148/582) were undecided...
  48. ncbi request reprint Unique roles of a data and safety monitoring board in vaccine safety trials with compressed timelines and urgent implications
    David Scheifele
    Canadian Association for Immunization Research and Evaluation, Vancouver, British Columbia, Canada
    Control Clin Trials 24:99-104. 2003
    ..Providing a safety valve for inevitable tensions between investigators and sponsor was an understated but significant role. Lessons from our experience will be particularly pertinent to future studies of pandemic influenza vaccines...
  49. ncbi request reprint Prevalence of hearing loss in primary school children in Zimbabwe
    Brian D Westerberg
    Division of Otolaryngology, University of British Columbia, St Paul s Rotary Hearing Clinic, Providence 2, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6
    Int J Pediatr Otorhinolaryngol 69:517-25. 2005
    ..The objective of the study was to determine the prevalence of significant hearing impairment in children attending primary school in the country of Zimbabwe...
  50. ncbi request reprint Human illness and isolation of low-pathogenicity avian influenza virus of the H7N3 subtype in British Columbia, Canada
    Danuta M Skowronski
    J Infect Dis 193:899-900; author reply 900-1. 2006
  51. ncbi request reprint Identification of severe acute respiratory syndrome in Canada
    Susan M Poutanen
    Toronto Medical Laboratories and Mount Sinai Hospital Department of Microbiology, Toronto, Canada
    N Engl J Med 348:1995-2005. 2003
    ..This report summarizes the initial epidemiologic findings, clinical description, and diagnostic findings that followed the identification of SARS in Canada...
  52. ncbi request reprint The clinical spectrum of the oculo-respiratory syndrome after influenza vaccination
    Gaston De Serres
    Quebec National Institute of Public Health, Quebec, Que, Canada
    Vaccine 21:2354-61. 2003
    ....
  53. ncbi request reprint Aggregate content influences the Th1/Th2 immune response to influenza vaccine: evidence from a mouse model
    Shawn Babiuk
    Vaccine and Infectious Disease Organization, Saskatoon, SK, Canada
    J Med Virol 72:138-42. 2004
    ..We confirm that vaccine aggregates deviate the immune response to a greater Th2 cytokine pattern with potential implications for vaccine screening, safety, and efficacy...
  54. ncbi request reprint Network theory and SARS: predicting outbreak diversity
    Lauren Ancel Meyers
    Section of Integrative Biology and Institute for Cellular and Molecular Biology, University of Texas at Austin, 1 University Station C0930, Austin, TX 78712, USA
    J Theor Biol 232:71-81. 2005
    ..We offer quantitative insight into the heterogeneity of SARS outbreaks worldwide, and illustrate the utility of this approach for assessing public health strategies...
  55. ncbi request reprint Recurrence risk of oculorespiratory syndrome after influenza vaccination: randomized controlled trial of previously affected persons
    Gaston De Serres
    Institut National de Sante Publique du Quebec, Quebec, Canada
    Arch Intern Med 164:2266-72. 2004
    ..Oculorespiratory syndrome (ORS) after influenza vaccination has many features of an allergic reaction...
  56. ncbi request reprint Oculo-respiratory syndrome after influenza vaccination: trends over four influenza seasons
    Gaston De Serres
    Institut National de Sante Publique du Quebec, Canada
    Vaccine 23:3726-32. 2005
    ..Oculo-respiratory syndrome (ORS) following influenza vaccination was identified in Canada in 2000. This report describes trends of ORS reported during four consecutive seasons 2000, 2001, 2002 and 2003 in the province of Quebec, Canada...
  57. ncbi request reprint Detection of human influenza virus in the stool of children
    Susan H Wootton
    Pediatr Infect Dis J 25:1194-5. 2006
  58. doi request reprint The cost of preventing rabies at any cost: post-exposure prophylaxis for occult bat contact
    Caroline Huot
    Department of Social and Preventive Medicine, Laval University, Quebec, Canada
    Vaccine 26:4446-50. 2008
    ..Household bat exposure has become the most frequent reason for RPEP administration. Given the rarity of rabies, RPEP recommendations related to household bat exposure may warrant review...
  59. doi request reprint Bat rabies in the United States and Canada from 1950 through 2007: human cases with and without bat contact
    Gaston De Serres
    Institut National de Sante Publique du Quebec, Canada
    Clin Infect Dis 46:1329-37. 2008
    ..Since the 1980s, rare cases of rabies in humans in Canada and the United States have been almost exclusively caused by the bat-variant virus...