T Pickles

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. ncbi Rising prostate-specific antigen values during neoadjuvant androgen deprivation therapy: The importance of monitoring
    Paddy Niblock
    Radiation Therapy Program, Vancouver Center, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 65:59-64. 2006
  2. ncbi The risk of second malignancy in men with prostate cancer treated with or without radiation in British Columbia, 1984-2000
    Tom Pickles
    Radiation Oncology Program, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver V5Z 4E6, BC, Canada
    Radiother Oncol 65:145-51. 2002
  3. ncbi Incomplete testosterone suppression with luteinizing hormone-releasing hormone agonists: does it happen and does it matter?
    Tom Pickles
    Radiation programme, BC Cancer Agency, and Department of Radiotherapy and Developmental Radiotherapeutics, University of British Columbia, Vancouver, Canada
    BJU Int 110:E500-7. 2012
  4. ncbi The median non-prostate cancer survival is more than 10 years for men up to age 80 years who are selected and receive curative radiation treatment for prostate cancer
    Paul A Blood
    Radiation Oncology, BC Cancer Agency and University of British Columbia, Victoria, BC, Canada
    Radiat Oncol 2:17. 2007
  5. ncbi Expanded risk groups help determine which prostate radiotherapy sub-group may benefit from adjuvant androgen deprivation therapy
    Matthew Beasley
    British Columbia Cancer Agency, Vancouver, Canada
    Radiat Oncol 3:8. 2008
  6. ncbi Psychosocial barriers to active surveillance for the management of early prostate cancer and a strategy for increased acceptance
    Tom Pickles
    Radiation Program, BC Cancer Agency, Vancouver, BC, Canada
    BJU Int 100:544-51. 2007
  7. ncbi The effect of smoking on outcome following external radiation for localized prostate cancer
    T Pickles
    Radiation Program, Columbia Cancer Agency, Vancouver Clinic, British Columbia, Canada
    J Urol 171:1543-6. 2004
  8. ncbi Brachytherapy or conformal external radiotherapy for prostate cancer: a single-institution matched-pair analysis
    Tom Pickles
    Prostate Outcomes and Provincial Prostate Brachytherapy Program, BC Cancer Agency, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 76:43-9. 2010
  9. ncbi Evaluation of the Houston biochemical relapse definition in men treated with prolonged neoadjuvant and adjuvant androgen ablation and assessment of follow-up lead-time bias
    Tom Pickles
    Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 57:11-8. 2003
  10. ncbi Prostate-specific antigen (PSA) bounce and other fluctuations: which biochemical relapse definition is least prone to PSA false calls? An analysis of 2030 men treated for prostate cancer with external beam or brachytherapy with or without adjuvant androge
    Tom Pickles
    British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 64:1355-9. 2006

Collaborators

Detail Information

Publications65

  1. ncbi Rising prostate-specific antigen values during neoadjuvant androgen deprivation therapy: The importance of monitoring
    Paddy Niblock
    Radiation Therapy Program, Vancouver Center, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 65:59-64. 2006
    ..035) and OS (p = 0.038). CONCLUSIONS: A subset of patients treated with N-ADT develop a rising PSA profile that likely represents early androgen resistance. They have significantly worse outcome...
  2. ncbi The risk of second malignancy in men with prostate cancer treated with or without radiation in British Columbia, 1984-2000
    Tom Pickles
    Radiation Oncology Program, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver V5Z 4E6, BC, Canada
    Radiother Oncol 65:145-51. 2002
    ..Increases in sarcomas in the RT group are probably treatment-related. Overall the increased second cancer risk for those undergoing radiation therapy was 1 in 220...
  3. ncbi Incomplete testosterone suppression with luteinizing hormone-releasing hormone agonists: does it happen and does it matter?
    Tom Pickles
    Radiation programme, BC Cancer Agency, and Department of Radiotherapy and Developmental Radiotherapeutics, University of British Columbia, Vancouver, Canada
    BJU Int 110:E500-7. 2012
    ..Interim measures of cancer control (PSA kinetics during LHRH therapy) were inferior in those with a breakthrough, and those with breakthroughs between 1.1 and 1.7 nmol/L had worse long-term biochemical control rates...
  4. ncbi The median non-prostate cancer survival is more than 10 years for men up to age 80 years who are selected and receive curative radiation treatment for prostate cancer
    Paul A Blood
    Radiation Oncology, BC Cancer Agency and University of British Columbia, Victoria, BC, Canada
    Radiat Oncol 2:17. 2007
    ..This finding suggests that radiation oncologists are able to appropriately select elderly men with greater than average life expectancy to receive curative radiation treatment...
  5. ncbi Expanded risk groups help determine which prostate radiotherapy sub-group may benefit from adjuvant androgen deprivation therapy
    Matthew Beasley
    British Columbia Cancer Agency, Vancouver, Canada
    Radiat Oncol 3:8. 2008
    ....
  6. ncbi Psychosocial barriers to active surveillance for the management of early prostate cancer and a strategy for increased acceptance
    Tom Pickles
    Radiation Program, BC Cancer Agency, Vancouver, BC, Canada
    BJU Int 100:544-51. 2007
    ..To review the psychosocial needs of men undergoing active surveillance (AS, the monitoring of early prostate cancer, with curative intervention only if the disease significantly progresses) for prostate cancer, and barriers to its uptake...
  7. ncbi The effect of smoking on outcome following external radiation for localized prostate cancer
    T Pickles
    Radiation Program, Columbia Cancer Agency, Vancouver Clinic, British Columbia, Canada
    J Urol 171:1543-6. 2004
    ..We investigated whether a smoking habit affects biochemical and survival outcome after curative external beam radiation therapy (EBRT) for localized prostate cancer...
  8. ncbi Brachytherapy or conformal external radiotherapy for prostate cancer: a single-institution matched-pair analysis
    Tom Pickles
    Prostate Outcomes and Provincial Prostate Brachytherapy Program, BC Cancer Agency, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 76:43-9. 2010
    ..This study was designed to overcome some of the limitations of case series studies by using a matched-pair design in patients treated contemporaneously with BT and external beam radiation therapy (EBRT) at a single institution...
  9. ncbi Evaluation of the Houston biochemical relapse definition in men treated with prolonged neoadjuvant and adjuvant androgen ablation and assessment of follow-up lead-time bias
    Tom Pickles
    Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 57:11-8. 2003
    ....
  10. ncbi Prostate-specific antigen (PSA) bounce and other fluctuations: which biochemical relapse definition is least prone to PSA false calls? An analysis of 2030 men treated for prostate cancer with external beam or brachytherapy with or without adjuvant androge
    Tom Pickles
    British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 64:1355-9. 2006
    ....
  11. ncbi Comparative 5-year outcomes of brachytherapy and surgery for prostate cancer
    Tom Pickles
    BCCA PB Program, Vancouver Clinic, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, BC, Canada
    Brachytherapy 10:9-14. 2011
    ..To compare the predicted outcome by radical retropubic prostatectomy (RRP) of patients actually treated with prostate brachytherapy (PB) for low- and intermediate-risk prostate cancer, using a surgical nomogram...
  12. ncbi Pion radiation for high grade astrocytoma: results of a randomized study
    T Pickles
    British Columbia Cancer Agency, Vancouver, Canada
    Int J Radiat Oncol Biol Phys 37:491-7. 1997
    ..This study attempted to compare within a randomized study the outcome of pion radiation therapy vs. conventional photon irradiation for the treatment of high-grade astrocytomas...
  13. ncbi Pion conformal radiation of prostate cancer: results of a randomized study
    T Pickles
    Radiation Oncology Program, BC Cancer Agency, Vancouver, Canada
    Int J Radiat Oncol Biol Phys 43:47-55. 1999
    ..To compare the efficacy of pion radiation therapy with conventional external beam photon therapy, for the treatment of locally advanced stage T3/4, N0, M0 adenocarcinoma of the prostate...
  14. ncbi Evaluating the Phoenix definition of biochemical failure after (125)I prostate brachytherapy: Can PSA kinetics distinguish PSA failures from PSA bounces?
    Anna Thompson
    British Columbia Cancer Agency, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 78:415-21. 2010
    ..To evaluate the prostate-specific antigen (PSA) kinetics of PSA failure (PSAf) and PSA bounce (PSAb) after permanent (125)I prostate brachytherapy (PB)...
  15. ncbi Population-based study of biochemical and survival outcomes after permanent 125I brachytherapy for low- and intermediate-risk prostate cancer
    W J Morris
    British Columbia Cancer Centre, Vancouver, British Columbia, Canada
    Urology 73:860-5; discussion 865-7. 2009
    ..To analyze the biochemical and survival outcomes after permanent low-dose-rate prostate brachytherapy in a large, consecutive, population-based cohort of patients...
  16. ncbi What's a man to do? Treatment options for localized prostate cancer
    Tom Pickles
    Genito Urinary Tumour Group, British Columbia Cancer Agency, Vancouver
    Can Fam Physician 50:65-72. 2004
    ..Patients trying to decide about treatment ask family physicians for advice. This article sets out a framework to aid patients (and physicians) in the decision...
  17. ncbi PSA doubling time post radiation: the effect of neoadjuvant androgen ablation
    S Tyldesley
    Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
    Can J Urol 11:2316-21. 2004
    ..CONCLUSION: The use of prolonged NAA in men treated with RT does not itself cause a more rapid PSAdt when relapse occurs. Faster relapse observed in these men is due to intrinsically more aggressive tumors prior to treatment...
  18. ncbi Pions--the potential for therapeutic gain in locally advanced prostate cancer: dose escalation and toxicity studies
    T Pickles
    B C Cancer Agency, Vancouver, Canada
    Int J Radiat Oncol Biol Phys 21:1005-11. 1991
    ..Local response rates of 94% are reported. A Phase III study is now under way...
  19. ncbi Testosterone recovery following prolonged adjuvant androgen ablation for prostate carcinoma
    Tom Pickles
    Vancouver Cancer Clinic, BC Cancer Agency, Canada
    Cancer 94:362-7. 2002
    ..Most men treated for up to 2 years recover normal testosterone levels after cessation of adjuvant androgen ablation, and the limited data available in the current study on patients treated for 3 years also suggests most will recover...
  20. ncbi Decline in urinary retention incidence in 805 patients after prostate brachytherapy: the effect of learning curve?
    Mira Keyes
    Department of Radiation Oncology, Vancouver Cancer Centre, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 64:825-34. 2006
    ..To evaluate the incidence and factors predictive of acute urinary retention (AUR) in 805 consecutive patients treated with prostate brachytherapy monotherapy and to examine the possible effect of a learning curve...
  21. ncbi Hemoglobin levels do not predict biochemical outcome for localized prostate cancer treated with neoadjuvant androgen-suppression therapy and external-beam radiotherapy
    Howard Huaihan Pai
    Radiation Oncology Program, British Columbia Cancer Agency Vancouver Island Centre, Victoria, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 65:990-8. 2006
    ..To investigate whether hemoglobin (Hb) levels affect outcome in men with localized prostate adenocarcinoma (LPA) treated with neoadjuvant androgen-suppression therapy (NAST) and external-beam radiotherapy (EBRT)...
  22. ncbi Relationship between delay in radiotherapy and biochemical control in prostate cancer
    Winkle Kwan
    Radiation Therapy Program of the B C Cancer Agency, Fraser Valley Centre, Surrey, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 66:663-8. 2006
    ..The aim of this study was to investigate whether a delay in radiotherapy is associated with a poorer biochemical control for prostate cancer...
  23. ncbi Pretreatment PSA velocity as a predictor of disease outcome following radical radiation therapy
    David Palma
    Radiation Oncology Program, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 67:1425-9. 2007
    ..This study aimed to independently verify if pretreatment PSAV is associated with biochemical disease-free survival (bDFS), DSS, or OS in men undergoing radiation therapy...
  24. ncbi Long-term outcomes for patients with limited stage follicular lymphoma: involved regional radiotherapy versus involved node radiotherapy
    Belinda A Campbell
    Department of Radiation Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Cancer 116:3797-806. 2010
    ....
  25. ncbi Pretreatment prostate-specific antigen velocity is associated with development of distant metastases and prostate cancer mortality in men treated with radiotherapy and androgen-deprivation therapy
    David Palma
    Radiation Oncology Program, British Columbia Cancer Agency, Vancouver, BC, Canada
    Cancer 112:1941-8. 2008
    ..This study was undertaken to determine whether pretreatment PSAV is associated with biochemical disease-free survival, patterns of recurrence, and survival outcomes in men treated with radiation therapy and ADT...
  26. ncbi Urinary symptom flare in 712 125I prostate brachytherapy patients: long-term follow-up
    Mira Keyes
    Department of Surgery, University of British Columbia, Provincial Prostate Brachytherapy Program, British Columbia Cancer Agency, 600 W 10th Avenue, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 75:649-55. 2009
    ....
  27. ncbi Factors influencing men undertaking active surveillance for the management of low-risk prostate cancer
    B Joyce Davison
    Department of Urology, University of British Columbia, Prostate Centre at Vancouver General Hospital, Vancouver, Canada
    Oncol Nurs Forum 36:89-96. 2009
    ..To identify and describe decision-making influences on men who decide to manage their low-risk prostate cancer with active surveillance...
  28. ncbi Obesity as a predictor of biochemical recurrence and survival after radiation therapy for prostate cancer
    David Palma
    Radiation Oncology Program, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    BJU Int 100:315-9. 2007
    ....
  29. ncbi Predictive factors for acute and late urinary toxicity after permanent prostate brachytherapy: long-term outcome in 712 consecutive patients
    Mira Keyes
    Vancouver Cancer Center, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 73:1023-32. 2009
    ....
  30. ncbi Evaluation of dosimetric parameters and disease response after 125 iodine transperineal brachytherapy for low- and intermediate-risk prostate cancer
    W James Morris
    Vancouver Cancer Centre, Vancouver, Canada
    Int J Radiat Oncol Biol Phys 73:1432-8. 2009
    ....
  31. ncbi Involved-nodal radiation therapy as a component of combination therapy for limited-stage Hodgkin's lymphoma: a question of field size
    Belinda A Campbell
    Department of Radiation Oncology, Pathology, and Medical Oncology, British Columbia Cancer Agency and the University of British Columbia, Vancouver, Canada
    J Clin Oncol 26:5170-4. 2008
    ..Recent publications recommend a further reduction to involved-nodal radiation therapy (INRT), however, this has not been clinically validated...
  32. ncbi The treatment of primary central nervous system lymphoma in 122 immunocompetent patients: a population-based study of successively treated cohorts from the British Colombia Cancer Agency
    Tamara N Shenkier
    Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    Cancer 103:1008-17. 2005
    ..The objective of this study was to evaluate the clinical outcome of a population-based cohort of immunocompetent patients with primary central nervous system lymphoma (PCNSL) treated with 3 different strategies over 13 years...
  33. ncbi 125I reimplantation in patients with poor initial dosimetry after prostate brachytherapy
    Mira Keyes
    Department of Radiation Oncology, Vancouver Cancer Centre, British Columbia Cancer Agency, 600 W 10th Avenue, Vancouver, BC V5Z 4E6, Canada
    Int J Radiat Oncol Biol Phys 60:40-50. 2004
    ..In this case report, we describe 7 patients with suboptimal dosimetry after (125)I prostate brachytherapy who underwent a second implant procedure to improve the dosimetric coverage of the prostate...
  34. ncbi Long-term androgen deprivation therapy improves survival in prostate cancer patients presenting with prostate-specific antigen levels > 20 ng/mL
    Eric Berthelet
    Vancouver Island Centre, BC Cancer Agency, Victoria, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 63:781-7. 2005
    ..To assess the benefit of androgen deprivation (AD) and its optimal duration in patients with prostate cancer treated with external beam radiotherapy, who present with prostate-specific antigen levels > 20 ng/mL...
  35. ncbi Asian race and impact on outcomes after radical radiotherapy for localized prostate cancer
    Ada Man
    Department of Radiation and Medical Oncology, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6
    J Urol 170:901-4. 2003
    ..Survival outcomes after radiotherapy are the same for the 2 populations...
  36. ncbi Impact of neoadjuvant androgen ablation and other factors on late toxicity after external beam prostate radiotherapy
    Mitchell Liu
    Fraser Valley Centre, Surrey, BC, Canada
    Int J Radiat Oncol Biol Phys 58:59-67. 2004
    ..To evaluate the late toxicity profile of prostate cancer patients treated with external beam radiotherapy, to investigate the possible risk factors for late toxicity, and to determine whether neoadjuvant androgen ablation (NAA) is a factor...
  37. ncbi PSA failure and the risk of death in prostate cancer patients treated with radiotherapy
    Winkle Kwan
    Radiation Therapy Program, Fraser Valley Centre, British Columbia Cancer Agency, Surrey, British Columbia, Canada
    Int J Radiat Oncol Biol Phys 60:1040-6. 2004
    ..To determine the relationship between prostate-specific antigen (PSA) failure and cause-specific and overall survival in prostate cancer patients treated with radical radiotherapy...
  38. ncbi Intervention after PSA failure: examination of intervention time and subsequent outcomes from a prospective patient database
    Charmaine Kim-Sing
    Radiation Oncology, BC Cancer Agency, Vancouver BC, Canada
    Int J Radiat Oncol Biol Phys 60:463-9. 2004
    ..To investigate timing of intervention for solitary biochemical relapse following external beam radiation therapy (EBRT) for localized prostate cancer, and to assess the impact on survival...
  39. ncbi Report on the quality of life analysis from the phase III trial of pion versus photon radiotherapy in locally advanced prostate cancer
    G G Duncan
    Radiation Oncology Program, British Columbia Cancer Agency, Vancouver Clinic, and University of British Columbia, 600 West 10th Avenue, Vancouver, Canada
    Eur J Cancer 36:759-65. 2000
    ..There was a significant impact from hormonal therapy at relapse. Hormonal treatment produced a stepwise significant worsening in global QOL, particularly for physical and psychological domains...
  40. ncbi What is the optimal duration of androgen deprivation therapy in prostate cancer patients presenting with prostate-specific antigen levels > 20 ng/ml?
    Eric Berthelet
    Vancouver Island Centre, BC Cancer Agency, University of British Columbia, British Columbia, Canada
    Can J Urol 14:3621-7. 2007
    ..To evaluate the optimal duration of androgen deprivation therapy (ADT) in patients with prostate cancer treated with external beam radiotherapy (EBRT), who present with PSA levels > 20 ng/mL...
  41. ncbi Concurrent modified PCV chemotherapy and radiotherapy in newly diagnosed grade IV astrocytoma
    Colleen Murphy
    UBC Department of Medicine, Vancouver Hospital and Heather Sciences Center, British Columbia, Canada
    J Neurooncol 57:215-20. 2002
    ..A phase III trial would help delineate the true effectiveness of concurrent CT in this population. Modified PCV is safe and reasonably well tolerated...
  42. ncbi Current status of PSA screening. Early detection of prostate cancer
    Tom Pickles
    Genito-Urinary Tumour Group, British Columbia Cancer Agency, Vancouver
    Can Fam Physician 50:57-63. 2004
    ....
  43. ncbi The self-management of uncertainty among men undertaking active surveillance for low-risk prostate cancer
    John L Oliffe
    School of Nursing, Department of Urological Sciences, University of British Columbia, and Prostate Centre, Vancouver General Hospital, Vancouver, British Columbia, Canada
    Qual Health Res 19:432-43. 2009
    ..Although most participants exhibited typical men's health practices, it is clear that tailored AS psychosocial interventions will benefit men and their families...
  44. ncbi Urinary incontinence in prostate cancer patients treated with external beam radiotherapy
    Mitchell Liu
    Fraser Valley Centre, British Columbia Cancer Agency, 13750 96th Avenue, Surrey, BC, Canada
    Radiother Oncol 74:197-201. 2005
    ..Associated risk factors are pre-RT TURP and the presence of increased acute GU toxicity. Post-radiaton TURP increases the risk of incontinence five-fold...
  45. ncbi PSA doubling time kinetics during prostate cancer biochemical relapse after external beam radiation therapy
    Andrew Tom Bates
    Department of Radiation Oncology, British Columbia Cancer Agency, University of British Columbia, Vancouver, BC, Canada
    Int J Radiat Oncol Biol Phys 62:148-53. 2005
    ..This greater than constant exponential PSA growth is presumably the catalyst for secondary intervention. Otherwise, PSADT did not change during prostate cancer biochemical relapse...
  46. ncbi What happens to testosterone after prostate radiation monotherapy and does it matter?
    Tom Pickles
    British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    J Urol 167:2448-52. 2002
    ..We describe the phenomenon in detail and assess the impact on biochemical control and prostate specific antigen (PSA) doubling time in patients with relapse...
  47. ncbi The case for dose escalation versus adjuvant androgen deprivation therapy for intermediate risk prostate cancer
    Tom Pickles
    Radiation Program, BC Cancer Agency, Vancouver, BC, Canada
    Can J Urol 13:68-71. 2006
    ..Further randomized trials comparing and or combining the two treatment strategies are required...
  48. ncbi Volumetric modulated Arc therapy and conventional intensity-modulated radiotherapy for simultaneous maximal intraprostatic boost: a planning comparison study
    R Shaffer
    British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia, Canada
    Clin Oncol (R Coll Radiol) 21:401-7. 2009
    ..8Gy without exceeding organ at risk (OAR) dose-volume constraints...
  49. ncbi The treatment of choroidal melanoma with 198 Au plaque brachytherapy
    A Karvat
    British Columbia Cancer Agency, Vancouver Cancer Centre, 600 West 10th Avenue, B C, V5Z 4E6, Vancouver, Canada
    Radiother Oncol 59:153-6. 2001
    ..Seventy-seven of the 79 patients were analyzable for this study...
  50. ncbi The changing face of prostate cancer in British Columbia 1988-2000
    Tom Pickles
    Radiation Oncology Program and Genito-Urinary Tumour Group, British Columbia Cancer Agency, Vancouver, BC, Canada
    Can J Urol 9:1551-7. 2002
    ..Stage migration towards better prognosis tumours occurring in younger men has led to the increased use of surgery and brachytherapy and decreased use of external radiation...
  51. ncbi GU radiation oncologists consensus on bone loss from androgen deprivation
    Graeme G Duncan
    BC Cancer Agency, Vancouver, British Columbia, Canada
    Can J Urol 13:2962-6. 2006
    ..This is now adopted as national practice guidelines for radiation oncologists employed prolonged ADT in prostate cancer patients...
  52. ncbi A randomised trial of cranberry versus apple juice in the management of urinary symptoms during external beam radiation therapy for prostate cancer
    G Campbell
    Vancouver Cancer Centre, Vancouver, British Columbia, Canada
    Clin Oncol (R Coll Radiol) 15:322-8. 2003
    ..CONCLUSIONS: This study shows no significant difference in the urinary symptoms experienced during EBRT related to the consumption of cranberry juice compared with apple juice...
  53. ncbi Radiotherapy for muscle-invasive urinary bladder cancer in elderly patients
    Alexander Agranovich
    BC Cancer Agency, Fraser Valley Cancer Centre, Surrey, British Columbia, Canada
    Can J Urol 10:2056-61. 2003
    ..Treatment related toxicity was low for any RT regimens. CONCLUSION: RT is well tolerated by EP with good baseline performance status. The role of accelerated fractionation should be tested by conducting randomized trials...
  54. ncbi Technology review: high-intensity focused ultrasound for prostate cancer
    Tom Pickles
    BC Cancer Agency, Vancouver BC, Canada
    Can J Urol 12:2593-7. 2005
    ..There are no data on the toxicity of subsequent standard curative therapies after HIFU. In view of the lack of efficacy outcomes, and in the presence of significant toxicity, HIFU should only be offered within a research setting...
  55. ncbi In regard to Kupelian et al.: impact of biochemical failure on overall survival after radiation therapy for localized prostate cancer in the PSA era. IJROBP 2002;52:704-711
    Winkle Kwan
    Int J Radiat Oncol Biol Phys 54:1577-9; author reply 1579. 2002
  56. ncbi Impact of providing audiotapes of primary adjuvant treatment consultations to women with breast cancer: a multisite, randomized, controlled trial
    Thomas F Hack
    Faculty of Nursing, University of Manitoba, Winnipeg, Manitoba, Canada
    J Clin Oncol 21:4138-44. 2003
    ....
  57. ncbi Duration of testosterone suppression and the risk of death from prostate cancer in men treated with radiation and 6 months of hormone therapy
    David Palma
    Cancer 112:2322-3; author reply 2323. 2008
  58. ncbi Percentage of biopsy cores positive for malignancy and biochemical failure following prostate cancer radiotherapy in 3,264 men: statistical significance without predictive performance
    Scott G Williams
    Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia
    Int J Radiat Oncol Biol Phys 70:1169-75. 2008
    ..To define and incorporate the impact of the percentage of positive biopsy cores (PPC) into a predictive model of prostate cancer radiotherapy biochemical outcome...
  59. ncbi An international multicenter study evaluating the impact of an alternative biochemical failure definition on the judgment of prostate cancer risk
    Scott G Williams
    Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
    Int J Radiat Oncol Biol Phys 65:351-7. 2006
    ..To evaluate the impact of an alternative biochemical failure (bF) definition on the performance of existing plus de novo prognostic models...
  60. ncbi A multicenter study demonstrating discordant results from electronic prostate-specific antigen biochemical failure calculation systems
    Scott G Williams
    Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia
    Int J Radiat Oncol Biol Phys 65:1494-500. 2006
    ..To evaluate the interobserver variation of four electronic biochemical failure (bF) calculators using three bF definitions...
  61. ncbi Re: Hermann et al., low testosterone levels and quality of life
    Tom Pickles
    Radiother Oncol 78:107-8. 2006
  62. ncbi Impact of providing audiotapes of primary treatment consultations to men with prostate cancer: a multi-site, randomized, controlled trial
    Thomas F Hack
    Faculty of Nursing, University of Manitoba, Winnipeg, Manitoba, Canada
    Psychooncology 16:543-52. 2007
    ..The purpose of this investigation was to systematically examine the efficacy of providing men with prostate cancer with an audiotape of their primary treatment consultation...
  63. ncbi In regards to Thames et al.: increasing external beam dose for T1-T2 prostate cancer: effect on risk groups. (Int J Radiat Oncol Biol Phys 2006;65:975-981)
    Tom Pickles
    Int J Radiat Oncol Biol Phys 67:318-9; author reply 319. 2007
  64. ncbi Prostate cancer radiotherapy 2002: the way forward
    Himu Lukka
    Juravinski Cancer Centre, 699 Concession Street, Hamilton, Ontario L8V 5C2, Canada
    Can J Urol 12:2521-31. 2005
    ..Results from ongoing clinical trials will provide insight into these questions and will assist in the design of future clinical trials...
  65. ncbi Re: A prospective analysis of the time to normalization of serum androgens following 6 months of androgen deprivation therapy in patients on a randomized phase III clinical trial using limited hormonal therapy
    Tom Pickles
    J Urol 174:2423-4; author reply 2424. 2005