Qin Ouyang

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. ncbi request reprint Age-associated accumulation of CMV-specific CD8+ T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1)
    Qin Ouyang
    Section for Transplantation Immunology and Immunohematology, University of Tubingen, Germany
    Exp Gerontol 38:911-20. 2003
  2. ncbi request reprint Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    Qin Ouyang
    Tuebingen Ageing and Tumour Immunology Group, Section for Transplantation Immunology and Immunohematology, University of Tubingen, Tubingen, Germany
    J Clin Immunol 23:247-57. 2003
  3. ncbi request reprint Dysfunctional CMV-specific CD8(+) T cells accumulate in the elderly
    Qin Ouyang
    Tubingen Ageing and Tumour Immunology Group, Section for Transplantation Immunology and Immunohematology, University of Tubingen, Tubingen, Germany
    Exp Gerontol 39:607-13. 2004
  4. ncbi request reprint Compromised interferon gamma (IFN-gamma) production in the elderly to both acute and latent viral antigen stimulation: contribution to the immune risk phenotype?
    Qin Ouyang
    Tubingen Ageing and Tumour Immunology Group, Section for Transplantation Immunology and Immunohaematology, Center for Medical Research, ZMF, University of Tubingen, Germany
    Eur Cytokine Netw 13:392-4. 2002
  5. ncbi request reprint Development of an MHC-class I peptide selection assay combining nanoparticle technology and matrix-assisted laser desorption/ionisation mass spectrometry
    Thomas Flad
    Section for Transplantation Immunology and Immunohematology, University of Tuebingen, Germany
    J Immunol Methods 283:205-13. 2003
  6. ncbi request reprint An age-related increase in the number of CD8+ T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness
    Qin Ouyang
    Tuebingen Ageing and Tumour Immunology Group, Center for Medical Research, ZMF, Waldhoernlestr 22, 72072, Tuebingen, Germany
    Mech Ageing Dev 124:477-85. 2003
  7. ncbi request reprint Expansion of peripheral CD8+ CD28- T cells in response to Epstein-Barr virus in patients with rheumatoid arthritis
    Tatjana Klatt
    Section for Transplantation Immunology and Immunohematology, University Clinics, Tuebingen, Germany
    J Rheumatol 32:239-51. 2005
  8. ncbi request reprint [The expression of API2-MALT1 fusion gene and its influence on the cellular apoptosis and proliferation in gastrointestinal MALT lymphoma]
    Wen Xiu Yang
    Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 35:172-5. 2004
  9. ncbi request reprint Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
    Nathan E Standifer
    Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Room 260, Seattle WA, 98101, USA
    Diabetes 55:3061-7. 2006
  10. ncbi request reprint Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes
    Qin Ouyang
    Department of Pathology and Laboratory Medicine, Child and Family Research Institute, University of British Columbia and British Columbia Children s Hospital, 4480 Oak St, Vancouver, British Columbia V6H 3V4, Canada
    Diabetes 55:3068-74. 2006

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Age-associated accumulation of CMV-specific CD8+ T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1)
    Qin Ouyang
    Section for Transplantation Immunology and Immunohematology, University of Tubingen, Germany
    Exp Gerontol 38:911-20. 2003
    ..The presence of clonal expansions of such virus-specific cells may shrink the available repertoire for other antigens and contribute to the increased incidence of infectious disease in the elderly...
  2. ncbi request reprint Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    Qin Ouyang
    Tuebingen Ageing and Tumour Immunology Group, Section for Transplantation Immunology and Immunohematology, University of Tubingen, Tubingen, Germany
    J Clin Immunol 23:247-57. 2003
    ....
  3. ncbi request reprint Dysfunctional CMV-specific CD8(+) T cells accumulate in the elderly
    Qin Ouyang
    Tubingen Ageing and Tumour Immunology Group, Section for Transplantation Immunology and Immunohematology, University of Tubingen, Tubingen, Germany
    Exp Gerontol 39:607-13. 2004
    ..This might account for the increased incidence of many infectious diseases in the elderly...
  4. ncbi request reprint Compromised interferon gamma (IFN-gamma) production in the elderly to both acute and latent viral antigen stimulation: contribution to the immune risk phenotype?
    Qin Ouyang
    Tubingen Ageing and Tumour Immunology Group, Section for Transplantation Immunology and Immunohaematology, Center for Medical Research, ZMF, University of Tubingen, Germany
    Eur Cytokine Netw 13:392-4. 2002
    ..Further longitudinal studies are needed to demonstrate whether cytokines such as IFN-g are also part of the IRP. Improving the definition of the IRP will help to understand and thus prevent or reverse age-associated immune dysfunction...
  5. ncbi request reprint Development of an MHC-class I peptide selection assay combining nanoparticle technology and matrix-assisted laser desorption/ionisation mass spectrometry
    Thomas Flad
    Section for Transplantation Immunology and Immunohematology, University of Tuebingen, Germany
    J Immunol Methods 283:205-13. 2003
    ..The advantage of the system is that the bound peptides can be unambiguously identified without any prior modification (e.g. radioactive or fluorescence labelling), even from complex peptide mixtures...
  6. ncbi request reprint An age-related increase in the number of CD8+ T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness
    Qin Ouyang
    Tuebingen Ageing and Tumour Immunology Group, Center for Medical Research, ZMF, Waldhoernlestr 22, 72072, Tuebingen, Germany
    Mech Ageing Dev 124:477-85. 2003
    ..This may help to explain the increased incidence and case-fatality caused by viruses and intracellular pathogens in the elderly...
  7. ncbi request reprint Expansion of peripheral CD8+ CD28- T cells in response to Epstein-Barr virus in patients with rheumatoid arthritis
    Tatjana Klatt
    Section for Transplantation Immunology and Immunohematology, University Clinics, Tuebingen, Germany
    J Rheumatol 32:239-51. 2005
    ....
  8. ncbi request reprint [The expression of API2-MALT1 fusion gene and its influence on the cellular apoptosis and proliferation in gastrointestinal MALT lymphoma]
    Wen Xiu Yang
    Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 35:172-5. 2004
    ..To investigate the expression of API2-MALT1 fusion gene mRNA and its effect on protein of API2, Caspase3 and Ki67 in gastrointestinal MALT lymphoma (Extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue)...
  9. ncbi request reprint Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
    Nathan E Standifer
    Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Room 260, Seattle WA, 98101, USA
    Diabetes 55:3061-7. 2006
    ..These data implicate peptides of ppIAPP, GFAP, and IGRP as CTL epitopes for a heterogenous CD8(+) T-cell response in type 1 subjects and antibody-positive relatives...
  10. ncbi request reprint Recognition of HLA class I-restricted beta-cell epitopes in type 1 diabetes
    Qin Ouyang
    Department of Pathology and Laboratory Medicine, Child and Family Research Institute, University of British Columbia and British Columbia Children s Hospital, 4480 Oak St, Vancouver, British Columbia V6H 3V4, Canada
    Diabetes 55:3068-74. 2006
    ..These data suggest that many beta-cell epitopes are recognized by CTLs in recent-onset type 1 diabetic patients. These epitopes may be important in the pathogenesis of type 1 diabetes...
  11. pmc Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita
    Hinh Ly
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
    Blood 106:1246-52. 2005
    ....
  12. ncbi request reprint Basic biology and clinical impact of immunosenescence
    Wolfgang M Wagner
    Zentrum für Medizinische Forschung, Universitätsklinik Tübingen, Waldhornlestrasse 22, 72072, Tubingen, Germany
    Biogerontology 5:63-6. 2004
  13. ncbi request reprint Basic biology and clinical impact of immunosenescence
    Raquel Tarazona
    Department of Immunology, University Hospital Reina Sofia, University of Cordoba, Avda Menádez Pidal s n, 14004 Cordoba, Spain
    Exp Gerontol 37:183-9. 2002
    ..We briefly summarise some of the highlights of the meeting here, and bring together in this special issue a collection of peer-reviewed papers reflecting the broad approach to immunosenescence currently being applied...
  14. ncbi request reprint [Effects of NaBT and NSAIDs on colorectal adenoma-carcinoma cells]
    Zhihong Zhang
    Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 34:544-5, 593. 2003
    ....
  15. ncbi request reprint Immunosenescence in Montecatini
    Graham Pawelec
    Center for Medical Research, University of Tubingen, Waldhornlestr 22, 720272 Tübingen, Germany Author for correspondence e mail fax 49 7071 294677
    Biogerontology 4:121-3. 2003
  16. ncbi request reprint Pathways to a robust immune response in the elderly
    Graham Pawelec
    Second Department of Internal Medicine, University of Tubingen Medical School, Waldhornlestr 22, D 72076 Tubingen, Germany
    Immunol Allergy Clin North Am 23:1-13. 2003
    ....
  17. ncbi request reprint [The growth inhibition of colorectal adenoma cells by sulindac and its mechanisms]
    Libin Huang
    Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, China
    Hua Xi Yi Ke Da Xue Xue Bao 33:101-3. 2002
    ..This study was conducted to assess the growth inhibition of colorectal adenoma cells by sulindac and identify the possible mechanisms...
  18. ncbi request reprint The abl/bcr gene product as a novel leukemia-specific antigen: peptides spanning the fusion region of abl/bcr can be recognized by both CD4+ and CD8+ T lymphocytes
    Wolfgang M Wagner
    Section for Transplantation Immunology and Immunohaematology, Second Department of Internal Medicine, Tübingen University Medical School, Tubingen, Germany
    Cancer Immunol Immunother 52:89-96. 2003
    ..Because abl/bcr is expressed in the majority of CML patients, it may represent a highly leukemia-specific antigen with potential use in immunotherapy...
  19. ncbi request reprint Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes'
    Graham Pawelec
    Tubingen Ageing and Tumour Immunology Group, Center for Medical Research, Waldhornlestrasse 22, D 72072 Tubingen, Germany
    Trends Immunol 23:330-2. 2002
  20. ncbi request reprint [The effects of butyrates and non-steroidal anti-inflammatory agents on HT-29 colonic carcinoma cells]
    Zhihong Zhang
    Department of Gastroenterology, The First Affiliated Hospital, Western China University of Medical Sciences, Chengdu 610041, China
    Zhonghua Nei Ke Za Zhi 41:153-5. 2002
    ..Adenocarcinoma cells HT-29 were used to investigate whether butyrates and non-steroidal anti-inflammatory agents (NSAIDs, aspirin and NS-398) would be effective adjuvants for inducing apoptosis and to probe its possible mechanisms...
  21. ncbi request reprint Telomere length in human natural killer cell subsets
    Qin Ouyang
    Terry Fox Laboratory, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada, V5Z 1L3
    Ann N Y Acad Sci 1106:240-52. 2007
    ..Telomere attrition in NK cells is a plausible cause for diminished NK cell function in the elderly...