Research Topics
Species | I A OlivottoSummaryAffiliation: British Columbia Country: Canada Publications
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Detail Information
Publications
Screening Mammography Program of British Columbia: pattern of use and health care system costsI A Olivotto
Screening Mammography Program of British Columbia, Vancouver
CMAJ 160:337-41. 1999..This report describes the changes that have occurred in the use of bilateral mammography in British Columbia since the provincial breast cancer screening program began in 1988...
Intervals longer than 20 weeks from breast-conserving surgery to radiation therapy are associated with inferior outcome for women with early-stage breast cancer who are not receiving chemotherapyIvo A Olivotto
BC Cancer Agency Vancouver Island Centre, Victoria, British Columbia, Canada
J Clin Oncol 27:16-23. 2009..To determine the interval from breast-conserving surgery (BCS) to radiation therapy (RT) that affects local control or survival...
Long-term survival of patients with supraclavicular metastases at diagnosis of breast cancerIvo A Olivotto
Breast Cancer Outcomes Unit, Victoria, British Columbia, Canada
J Clin Oncol 21:851-4. 2003....
A clinical trial of breast radiation therapy versus breast plus regional radiation therapy in early-stage breast cancer: the MA20 trialIvo A Olivotto
Radiation Oncology, British Columbia Cancer Agency and University of British Columbia, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC V8R 6V5, Canada
Clin Breast Cancer 4:361-3. 2003
Population-based validation of the prognostic model ADJUVANT! for early breast cancerIvo A Olivotto
Breast Cancer Outcomes Unit, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC V8R 6V5, Canada
J Clin Oncol 23:2716-25. 2005..Adjuvant! (www.adjuvantonline.com) is a web-based tool that predicts 10-year breast cancer outcomes with and without adjuvant systemic therapy, but it has not been independently validated...
Prognosis, treatment, and recurrence of breast cancer for women attending or not attending the Screening Mammography Program of British ColumbiaI A Olivotto
The Screening Mammography Program of British Columbia, British Columbia Cancer Agency, The University of British Columbia, Vancouver, Canada
Breast Cancer Res Treat 54:73-81. 1999..These favorable surrogate endpoints suggest that the benefits of breast screening as demonstrated by randomized trials can be translated into community practice by an organized breast screening program...
Waiting for a diagnosis after an abnormal screening mammogram. SMPBC diagnostic process workgroup. Screening Mammography Program of British ColumbiaI A Olivotto
University of British Columbia, Vancouver
Can J Public Health 91:113-7. 2000..This report evaluated the timeliness of diagnosis after an abnormal screening mammogram in the Screening Mammography Program of British Columbia (SMPBC)...
Ten years of breast screening in the Screening Mammography Program of British Columbia, 1988-97I A Olivotto
Screening Mammography Program of British Columbia BC, 8th Floor, 686 West Broadway, Vancouver, BC, Canada V5Z 1G1
J Med Screen 7:152-9. 2000..To evaluate 10 years outcomes of the Screening Mammography Program of British Columbia (SMPBC) and determine if breast screening targets were being achieved among women aged 40-80+ years...
Tubular carcinoma of the breast: a population-based study of nodal metastases at presentation and of patterns of relapseH A Kader
Breast Cancer Outcomes Unit, Vancouver Island Cancer Center, Victoria, Canada
Breast J 7:8-13. 2001..In view of the low incidence of axillary node metastases at presentation in the low-risk TCB subset (7%), axillary dissection may be omitted as part of the initial surgical management in these patients...
Patients with t1 to t2 breast cancer with one to three positive nodes have higher local and regional recurrence risks compared with node-negative patients after breast-conserving surgery and whole-breast radiotherapyPauline T Truong
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 73:357-64. 2009..To evaluate locoregional recurrence according to nodal status in women with T1 to T2 breast cancer and zero to three positive nodes (0-3N+) treated with breast-conserving surgery (BCS)...
Improving the time to diagnosis after an abnormal screening mammogramI A Olivotto
Screening Mammography Program of British Columbia, Victoria, BC
Can J Public Health 92:366-71. 2001..CONCLUSIONS: Process changes can improve the time to diagnosis after an abnormal breast screen, with similar or lower physician costs per subject. Facilitating the referral process had the greatest impact...
Lymphovascular invasion is associated with reduced locoregional control and survival in women with node-negative breast cancer treated with mastectomy and systemic therapyPauline T Truong
British Columbia Cancer Agency-Vancouver Island Centre and the Department of Surgery, University of British Columbia, Victoria, BC, Canada
J Am Coll Surg 200:912-21. 2005..Prospective research is required to define the role of adjuvant radiotherapy in these patients...
Locoregional recurrence risks in elderly breast cancer patients treated with mastectomy without adjuvant radiotherapyPauline T Truong
Radiation Therapy Program, Vancouver Island Centre, British Columbia Cancer Agency and the University of British Columbia, 2410 Lee Avenue, Victoria, BC, Canada V8R 6V5
Eur J Cancer 41:1267-77. 2005..Chronologic age alone should not preclude these women from consideration of adjuvant radiotherapy...
Increased use of adjuvant regional radiotherapy for node-positive breast cancer in British ColumbiaBoon Chua
Radiation Therapy and Systemic Therapy Programs, British Columbia Cancer Agency, Vancouver Island Center, Victoria, British Columbia, Canada
Breast J 10:38-44. 2004..001 for both). Publication of randomized trials and a coordinated guideline implementation process in British Columbia was associated with a significant increase in the use of regional RT in women with one to three positive nodes...
Management and outcomes of isolated axillary node recurrence in breast cancerDavid E Konkin
Division of Surgical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada
Arch Surg 141:867-72; discussion 872-4. 2006..0%. Multimodality management at the time of recurrence, including axillary surgery, radiation, and systemic therapy, significantly improved overall and disease-free survival...
Mega-dose vitamins and minerals in the treatment of non-metastatic breast cancer: an historical cohort studyM L Lesperance
Department of Mathematics and Statistics, University of Victoria, Victoria, British Columbia, Canada
Breast Cancer Res Treat 76:137-43. 2002..Alternative therapies such as mega-dose vitamins and minerals are commonly used by women with breast cancer, but their effect on recurrence and survival have rarely been evaluated...
Relationship between tumor location and relapse in 6,781 women with early invasive breast cancerC Lohrisch
Breast Cancer Outcomes Unit and Systemic and Radiation Therapy Programs of the British Columbia Cancer Agency, and Fraser Valley Cancer Centers and the Faculty of Medicine, University of British Columbia, Vancouver, Canada
J Clin Oncol 18:2828-35. 2000..To explore the independent prognostic impact of medial hemisphere tumor location in early breast cancer...
T1a breast carcinoma and the role of axillary dissectionNathan P Schneidereit
Department of Surgery, University of British Columbia, Vancouver
Arch Surg 138:832-7. 2003..70) or survival (P =.84). CONCLUSION: Higher tumor grade and lymphovascular and/or neural invasion increased the rate of nodal metastases in T1a tumors, but AD did not improve relapse rates or breast cancer-specific survival...
Does HER2 status influence locoregional failure rates in breast cancer patients treated with mastectomy for pT1-2pN0 disease?W Kwan
Radiation Therapy Program, Fraser Valley Centre, British Columbia, Canada
Ann Oncol 21:988-93. 2010..The impact of HER2 overexpression on the locoregional control of breast cancer is controversial...
Evolving treatment strategies for inflammatory breast cancer: a population-based survival analysisMiguel Panades
Breast Cancer Outcomes Unit, BC Cancer Agency-Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC, Canada
J Clin Oncol 23:1941-50. 2005..02), and CT type (P = .05). CONCLUSION: This retrospective analysis suggested that mastectomy, in conjunction with CT and RT, seemed to enhance locoregional control, whereas modern CT regimens seemed to improve BCSS...
3D ultrasound can contribute to planning CT to define the target for partial breast radiotherapyTanya S Berrang
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 73:375-83. 2009....
Survival outcome and cost-effectiveness with docetaxel and paclitaxel in patients with metastatic breast cancer: a population-based evaluationT Vu
Provincial Systemic Therapy Program, BC Cancer Agency, Vancouver, British Columbia, Canada
Ann Oncol 19:461-4. 2008..A randomized controlled trial showed longer overall survival (OS) with docetaxel compared with paclitaxel in metastatic breast cancer patients with prior exposure to anthracycline. We report a similar comparison using population-based data...
Comparison of 1- and 2-year screening intervals for women undergoing screening mammographyE S Wai
Radiation Therapy Program, BC Cancer Agency, Vancouver Island Centre, 2410 Lee Ave, Victoria, BC, Canada V8R 6V5
Br J Cancer 92:961-6. 2005..Annual compared to biennial mammography was associated with a 1.2% increase in the estimated 10-year breast cancer-specific survival for women aged 50-74 years, diagnosed with invasive breast cancer after screening programme attendance...
Clinical practice guidelines for the care and treatment of breast cancer: 11. LymphedemaS R Harris
School of Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC
CMAJ 164:191-9. 2001..SPONSOR: The steering committee was convened by Health Canada. COMPLETION DATE: October 2000...
Is mastectomy superior to breast-conserving treatment for young women?Genevieve Coulombe
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver, BC, Canada
Int J Radiat Oncol Biol Phys 67:1282-90. 2007..To examine whether modified radical mastectomy (MRM) improves outcomes compared with breast-conserving treatment (BCT) in young women...
Immunohistochemical detection using the new rabbit monoclonal antibody SP1 of estrogen receptor in breast cancer is superior to mouse monoclonal antibody 1D5 in predicting survivalMaggie C U Cheang
Genetic Pathology Evaluation Centre at Vancouver General Hospital, Prostate Centre, and University of British Columbia, Vancouver, British Columbia, Canada
J Clin Oncol 24:5637-44. 2006..CONCLUSION: SP1 represents an improved standard for ER immunohistochemistry assessment in breast cancer...
Outcomes of sentinel node biopsy for breast cancer in British Columbia, 1996 to 2001Boon Chua
Radiation Therapy Program, BC Cancer Agency, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC, V8R 6V5, Canada
Am J Surg 185:118-26. 2003..Increasing surgeon experience was not significantly associated with improvements in identification or false-negative rates. CONCLUSIONS: The potential of SNB was not fully translated into surgical practice in BC by 2001...
Influence of delay to diagnosis on prognostic indicators of screen-detected breast carcinomaIvo A Olivotto
Screening Mammography Program of British Columbia, British Columbia Cancer Agency, Vancouver British Columbia, Canada
Cancer 94:2143-50. 2002..Suspicion bias should be considered when interpreting the effect of delay on prognosis...
Waiting times from abnormal breast screen to diagnosis in 7 Canadian provincesI A Olivotto
Division of Radiation Oncology, University of British Columbia, Vancouver, BC
CMAJ 165:277-83. 2001..To ensure that targets for timeliness, adopted nationally in 1999, are realized, improved models of care or dissemination of existing efficient techniques to reach a diagnosis will be needed...
A comparative analysis of radiotherapy use and patient outcome in males and females with breast cancerG Macdonald
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Cancer Centre, BC, Canada
Ann Oncol 16:1442-8. 2005..The aim was to determine whether gender was a significant prognostic factor for post-mastectomy relapse, after accounting for known prognostic factors and delivery of radiotherapy...
Prognostic significance of the number of axillary lymph nodes removed in patients with node-negative breast cancerL Weir
Radiation Therapy Program, Breast Cancer Outcomes Unit, University of British Columbia, Vancouver, British Columbia, Canada
J Clin Oncol 20:1793-9. 2002..The objective of the study was to evaluate the association between the number of lymph nodes removed at axillary dissection and recurrence and survival for patients with node-negative invasive breast cancer...
Postmastectomy radiotherapy reduces locoregional recurrence in elderly women with high-risk breast cancerJ C Lee
Radiation Therapy Program, Vancouver Island Centre, British Columbia Cancer Agency, Canada
Clin Oncol (R Coll Radiol) 17:623-9. 2005..PMRT should be considered in the management of elderly women with these high-risk characteristics...
Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifenH F Kennecke
Division of Medical Oncology, British Columbia BC Cancer Agency, Canada
Ann Oncol 18:45-51. 2007..An individualized estimate of the risk of relapse and death after 5 years of tamoxifen could improve decisions regarding extended hormonal therapy...
Standardized assessment of breast cancer surgical scars integrating the Vancouver Scar Scale, Short-Form McGill Pain Questionnaire, and patients' perspectivesPauline T Truong
British Columbia Cancer Agency, Vancouver Island Centre, Victoria, British Columbia, Canada
Plast Reconstr Surg 116:1291-9. 2005..This article evaluates the application of the Vancouver Scar Scale, in conjunction with patients' scar self-rating and scar-related pain, in a cohort of breast cancer patients...
Increased use of regional radiotherapy is associated with improved outcome in a population-based cohort of women with breast cancer with 1-3 positive nodesElaine S Wai
BC Cancer Agency, Vancouver Island Centre, Radiation Therapy Program, Canada
Radiother Oncol 97:301-6. 2010....
Radiotherapy omission after breast-conserving surgery is associated with reduced breast cancer-specific survival in elderly women with breast cancerPauline T Truong
British Columbia Cancer Agency, Vancouver Island Centre, British Columbia Cancer Agency, 2410 Lee Avenue, Victoria, BC, Canada V8R 6V5
Am J Surg 191:749-55. 2006..To evaluate the effect of radiotherapy (RT) omission on survival in older breast cancer patients treated with breast-conserving surgery...
Does a three-field electron/minitangent photon technique offer dosimetric advantages to a multifield, photon-only technique for accelerated partial breast irradiation?Aminudin R Mydin
Vancouver Island Centre, Victoria, British Columbia, Canada
Am J Clin Oncol 33:336-40. 2010..To determine whether 3-field electron/minitangent photons (mixed-modality) technique improved dosimetry compared with a multifield, photon-only technique for accelerated partial breast irradiation (APBI)...
Effect of radiotherapy boost and hypofractionation on outcomes in ductal carcinoma in situElaine S Wai
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Center, Victoria, British Columbia, Canada
Cancer 117:54-62. 2011..This study examined outcomes from whole breast RT, with or without a boost, and the impact of different dose-fractionation schedules in a population-based cohort of women with pure DCIS treated with breast-conserving surgery (BCS)...
Impact on survival of time from definitive surgery to initiation of adjuvant chemotherapy for early-stage breast cancerCaroline Lohrisch
Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver
J Clin Oncol 24:4888-94. 2006..To determine if time to start of adjuvant chemotherapy after curative surgery influences survival in early-stage breast cancer...
Reliability and validity testing of the Patient and Observer Scar Assessment Scale in evaluating linear scars after breast cancer surgeryPauline T Truong
British Columbia Cancer Agency, Vancouver Island Centre, Department of Surgery, University of British Columbia, Canada
Plast Reconstr Surg 119:487-94. 2007..The authors compared this tool to the Vancouver Scar Scale in a cohort of women with linear scars from breast cancer surgery...
Volumetric modulated arc therapy improves dosimetry and reduces treatment time compared to conventional intensity-modulated radiotherapy for locoregional radiotherapy of left-sided breast cancer and internal mammary nodesCarmen C Popescu
Radiation Therapy Program, British Columbia Cancer Agency Vancouver Island Centre, Victoria, British Columbia, Canada
Int J Radiat Oncol Biol Phys 76:287-95. 2010..This study compared VMAT with cIMRT and with conventional modified wide-tangent (MWT) techniques for locoregional radiotherapy for left-sided breast cancer, including internal mammary nodes...
Risk of early recurrence among postmenopausal women with estrogen receptor-positive early breast cancer treated with adjuvant tamoxifenHagen Kennecke
Division of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
Cancer 112:1437-44. 2008..An understanding of which patients are at risk of early recurrence while they are receiving tamoxifen may improve clinical decision making...
Human epidermal growth factor receptor 2 overexpression as a prognostic factor in a large tissue microarray series of node-negative breast cancersStephen Chia
Division of Medical Oncology, Breast Cancer Outcomes Unit, British Columbia Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada
J Clin Oncol 26:5697-704. 2008..This study assessed the prognostic impact of HER2 overexpression/amplification in a large series of node-negative breast cancers...
Does multicentric/multifocal breast cancer differ from unifocal breast cancer? An analysis of survival and contralateral breast cancer incidenceRinat Yerushalmi
Division of Medical Oncology, British Columbia Cancer Agency, 600 W 10th Avenue, Vancouver, BC, Canada V5Z 4E6
Breast Cancer Res Treat 117:365-70. 2009..174 (95% CI 1,004, 1.372). Conclusions M/M breast cancer did not increase the risk of metachronous CBC, but was associated with inferior BCSS...
Is multibeam IMRT better than standard treatment for patients with left-sided breast cancer?Wayne A Beckham
Radiation Therapy Program of the British Columbia Cancer Agency, Vancouver Island Centre, Victoria, British Columbia, Canada
Int J Radiat Oncol Biol Phys 69:918-24. 2007..The value of conformal intensity-modulated radiation therapy (IMRT) to avoid heart dose was studied...
Target volume delineation for partial breast radiotherapy planning: clinical characteristics associated with low interobserver concordanceRoss P Petersen
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, Canada
Int J Radiat Oncol Biol Phys 69:41-8. 2007..To examine variability in target volume delineation for partial breast radiotherapy planning and evaluate characteristics associated with low interobserver concordance...
The impact of new chemotherapeutic and hormone agents on survival in a population-based cohort of women with metastatic breast cancerStephen K Chia
Division of Medical Oncology, British Columbia Cancer Agency and the University of British Columbia, Vancouver and Victoria, British Columbia, Canada
Cancer 110:973-9. 2007..This study characterized the use and assessed the impact on survival of population-based access to new agents for the treatment of MBC...
Outcomes in patients with primary breast cancer and a subsequent diagnosis of endometrial cancer : comparison of cohorts treated with and without tamoxifenMandana Saadat
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, British Columbia, Canada
Cancer 110:31-7. 2007..The study compared tumor characteristics and survival in women with breast cancer who subsequently developed endometrial cancer with or without a history of tamoxifen use...
The ratio of positive to excised nodes identifies high-risk subsets and reduces inter-institutional differences in locoregional recurrence risk estimates in breast cancer patients with 1-3 positive nodes: an analysis of prospective data from British ColumPauline T Truong
Department of Radiation Oncology, British Columbia Cancer Agency Vancouver Island Centre, British Columbia Cancer Agency, University of British Columbia, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 68:59-65. 2007....
Impact of changing from annual to biennial mammographic screening on breast cancer outcomes in women aged 50-79 in British ColumbiaAndrew J Coldman
Surveillance and Outcomes Unit, British Columbia Cancer Agency, Suite 800, 686 W Broadway, Vancouver, BC V5Z 1G1, Canada
J Med Screen 15:182-7. 2008..The objective of this study was to compare breast cancer outcomes among women subject to different policies on mammography screening frequency...
When is CT-based postoperative seroma most useful to plan partial breast radiotherapy? Evaluation of clinical factors affecting seroma volume and clarityHosam A Kader
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 72:1064-9. 2008..To evaluate the effect of the time from surgery and other clinical factors on seroma volume and clarity and establish the optimal time to use the computed tomography (CT)-based seroma to plan partial breast irradiation (PBI)...
The prognostic significance of the percentage of positive/dissected axillary lymph nodes in breast cancer recurrence and survival in patients with one to three positive axillary lymph nodesPauline T Truong
British Columbia Cancer Agency, Vancouver Island Center, Radiation Therapy Program and the University of British Columbia, Victoria, British Columbia, Canada
Cancer 103:2006-14. 2005..The current study evaluated the prognostic impact of the percentage of positive/dissected lymph nodes on recurrence and survival in women with one to three positive lymph nodes...
Examining time intervals between diagnosis and treatment in the management of patients with limited stage small cell lung cancerEric Berthelet
Radiation Therapy and Systemic Therapy Programs, British Columbia Cancer Agency, Vancouver Island and Fraser Valley Centres, Victoria, BC, Canada
Am J Clin Oncol 29:21-6. 2006..To examine time intervals between diagnosis and treatment of limited stage small cell lung cancer (L-SCLC) and to evaluate its effect on clinical outcomes...
Population-based outcomes for small cell lung cancer: impact of standard management policies in British ColumbiaJanessa J Laskin
Division of Medical Oncology, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6
Lung Cancer 43:7-16. 2004..4 months (7.3 and 2.3% for 2- and 5-year survival, respectively). Standard treatment guidelines generated population-based survival outcomes that are similar to published clinical trials...
A positive margin is not always an indication for radiotherapy after mastectomy in early breast cancerPauline T Truong
Breast Cancer Outcomes Unit, British Columbia Cancer Agency Vancouver Island Centre and the University of British Columbia, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 58:797-804. 2004..This study examined relapse and survival among women with node-negative breast cancer and positive surgical margins after mastectomy...
Endoscopic response predicts for survival and organ preservation after primary chemoradiotherapy for esophageal cancerJan T W Lim
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, British Columbia, Canada
Int J Radiat Oncol Biol Phys 57:1328-35. 2003..To determine the role of endoscopic surveillance in predicting organ preservation and survival after primary chemoradiotherapy (CRT) for esophageal cancer...
Waist-to-hip ratio and breast cancer mortalityMarilyn J Borugian
Cancer Control Research Program, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
Am J Epidemiol 158:963-8. 2003..Elevated WHR was confirmed as a predictor of breast cancer mortality, with menopausal status and ER status at diagnosis found to be important modifiers of that relation...
Ten-year outcomes in a population-based cohort of node-negative, lymphatic, and vascular invasion-negative early breast cancers without adjuvant systemic therapiesStephen K Chia
Division of Medical Oncology, Breast Cancer Outcomes Unit, British Columbia Cancer Agency, 600 West 10th Ave, Vancouver, BC Canada, V5Z 4E6
J Clin Oncol 22:1630-7. 2004..We assessed the 10-year outcomes in a population-based cohort of node-negative (N-) lymphovascular negative (LV-) early breast cancers diagnosed from 1989 to 1991 who did not receive adjuvant systemic therapy...
Local and regional therapy for women with breast cancer in British ColumbiaT Gregory Hislop
Population and Preventative Oncology Program, BC Cancer Agency, Vancouver, British Columbia, Canada
Breast J 9:192-9. 2003..The increase in BCS, and high proportion completing radiation therapy, are encouraging and may be due in part to greater exposure to PPGs...
Satisfaction and anxiety for women during investigation of an abnormal screening mammogramT Gregory Hislop
Cancer Control, BC Cancer Agency, Vancouver, British Columbia, Canada
Breast Cancer Res Treat 76:245-54. 2002..Differences were found between biopsied and nonbiopsied women for several of these measures. Shortening the time to diagnosis positively influenced the client's perception of unnecessary delay...
Chronic arm morbidity after curative breast cancer treatment: prevalence and impact on quality of lifeWinkle Kwan
Radiation Therapy Program, Surgical Oncology Program, and Breast Cancer Outcomes Unit of the British Columbia Cancer Agency Fraser Valley Centre, Surrey, Canada
J Clin Oncol 20:4242-8. 2002..To determine the prevalence of and contributing factors for chronic arm morbidity including lymphedema in breast cancer patients after treatment and to assess the impact of arm morbidity on quality of life (QOL)...
Age-related variations in the use of axillary dissection: a survival analysis of 8038 women with T1-ST2 breast cancerPauline T Truong
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Cancer Centre, University of British Columbia, Victoria, British Columbia, Canada
Int J Radiat Oncol Biol Phys 54:794-803. 2002..The use of axillary dissection (AD) in women with invasive breast cancer is increasingly questioned. This study analyzes the survival in women with T1-2 breast cancer according to age and AD use...
Treatment of invasive breast carcinoma with ultrasound-guided radiofrequency ablationAllen H Hayashi
Department of Surgery, Vancouver Island Health Authority, Victoria, British Columbia, Canada
Am J Surg 185:429-35. 2003..Radiofrequency ablation (RFA) is a minimally invasive thermal ablation technique. This study reports the safety and efficacy of RFA as a minimally invasive strategy for breast cancers <3 cm diameter in postmenopausal women...
Selecting breast cancer patients with T1-T2 tumors and one to three positive axillary nodes at high postmastectomy locoregional recurrence risk for adjuvant radiotherapyPauline T Truong
Radiation Therapy Program, British Columbia Cancer Agency Vancouver Island Centre and University of British Columbia, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 61:1337-47. 2005....
Effect of soy phytoestrogens on hot flashes in postmenopausal women with breast cancer: a randomized, controlled clinical trialCheri L Van Patten
British Columbia Cancer Agency, Vancouver Cancer Centre, Vancouver Hospital and Health Sciences Centre, and University of British Columbia, Vancouver, British Columbia, Canada
J Clin Oncol 20:1449-55. 2002..This study evaluated the acceptability and effectiveness of a soy beverage containing phytoestrogens as a treatment for hot flashes in postmenopausal women with breast cancer...
Patient subsets with T1-T2, node-negative breast cancer at high locoregional recurrence risk after mastectomyPauline T Truong
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, University of British Columbia, Victoria, BC, Canada
Int J Radiat Oncol Biol Phys 62:175-82. 2005..To identify patient subsets with T1-T2N0 breast cancer at high risk of locoregional recurrence (LRR) who may warrant consideration for postmastectomy radiotherapy...
Preliminary reliability and validity testing of a new Skin Toxicity Assessment Tool (STAT) in breast cancer patients undergoing radiotherapyEric Berthelet
Radiation Therapy Program, British Columbia Cancer Agency BCCA Vancouver Island, Canada
Am J Clin Oncol 27:626-31. 2004..The STAT is an easy-to-use, standardized instrument to evaluate acute skin reaction and may be applied to clinical care and research in patients undergoing radiotherapy...
Health system costs of metastatic breast cancerE S Wai
The Breast Cancer Outcomes Unit, British Columbia Cancer Agency, Vancouver, Canada
Breast Cancer Res Treat 65:233-40. 2001..Inpatient costs accounted for the greatest proportion of the total, over 50% in all age groups. This data may be valuable in assessing the cost-effectiveness of interventions that are known to affect mortality due to breast cancer...
Consistency in seroma contouring for partial breast radiotherapy: impact of guidelinesElaine K Wong
Radiation Therapy Program, British Columbia (BC) Cancer Agency, Vancouver Island Centre, Victoria and Vancouver, BC, Canada
Int J Radiat Oncol Biol Phys 66:372-6. 2006..CONCLUSION: Guidelines can improve consistency among radiation oncologists performing target volume delineation for PBRT planning...
Facilitated "fast track" referral reduces time from abnormal screening mammogram to diagnosisMarilyn J Borugian
Screening Mammography Program of British Columbia, British Columbia Cancer Agency, Vancouver, BC
Can J Public Health 99:252-6. 2008..The purpose of this study was to compare time intervals for patients evaluated through the Fast Track process with patients who were not...
Correction of systematic setup errors in prostate radiation therapy: how many images to perform?Joanna J S Ludbrook
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, Victoria, BC, Canada
Med Dosim 30:76-84. 2005..A small tolerance level should be utilized with 2 mm giving good accuracy with minimal unnecessary shifts...
Short communication: Setup variations in locoregional radiotherapy for breast cancer: an electronic portal imaging studyP T Truong
Radiation Therapy Program, British Columbia Cancer Agency, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC, Canada V8R 6V5
Br J Radiol 78:742-5. 2005..2% of breast/chest wall tangential treatments and in 6.2% of supraclavicular nodal treatments. These data demonstrate that EPI is a useful tool to verify setup reproducibility in LRRT for breast cancer...
Practice patterns of lymph-node mapping and sentinel-node biopsy for breast cancer in British ColumbiaBoon Chua
BC Cancer Agency-Vancouver Island Centre and University of British Columbia, Vancouver, BC
Can J Surg 46:273-8. 2003..Developing consensus around written guidelines for the indications and techniques of SNB may reduce this variation...
The quality of life of elderly women who underwent radiofrequency ablation to treat breast cancerJillian Roberts
University of Victoria, British Columbia, Canada
Qual Health Res 16:762-72. 2006..The level of support received from the medical team, family and friends, and other cancer survivors also improved participant quality of life...
Measuring surgeon performance of sentinel lymph node biopsy in breast cancer treatment by cumulative sum analysisLindsey Lerch
Department of Surgery, Vancouver Island Health Authority, 302 2020 Richmond Road, Victoria, British Columbia, Canada V8R 6R5
Am J Surg 193:556-9; discussion 560. 2007..This study was performed to determine if surgeons' performance of sentinel lymph node biopsy (SLNB) for breast cancer varied with time and to devise a method to continuously evaluate that performance...
Tamoxifen with or without breast irradiation in women 50 years of age or older with early breast cancerAnthony W Fyles
Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON, Canada
N Engl J Med 351:963-70. 2004..We determined the effect of breast irradiation plus tamoxifen on disease-free survival and local relapse in women 50 years of age or older who had T1 or T2 node-negative breast cancer...
The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriersKelly A Metcalfe
Faculty of Nursing, University of Toronto, 50 St George Street, Toronto, ON, Canada, M5S 3H4
Gynecol Oncol 96:222-6. 2005..To estimate the risk of ovarian cancer after a primary diagnosis of breast cancer among women with a BRCA1 or BRCA2 mutation and to identify host and treatment-related factors that might modify the risk...
Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breastLawrence J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Cancer 103:1137-46. 2005..The objective of the current study was to determine the long-term outcome after breast-conservation surgery followed by definitive breast irradiation for women with mammographically detected DCIS of the breast...
Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancerLori J Pierce
Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
J Clin Oncol 24:2437-43. 2006..We compared the outcome of breast-conserving surgery and radiotherapy in BRCA1/2 mutation carriers with breast cancer versus that of matched sporadic controls...
Time to stop progesterone receptor testing in breast cancer managementIvo A Olivotto
J Clin Oncol 22:1769-70. 2004
Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situLawrence J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
Eur J Cancer 41:1715-23. 2005..Close follow-up after initial breast conservation treatment with radiation is warranted for the early detection of potentially salvageable local and local-regional recurrences...
Declining use of mastectomy for invasive breast cancer in Canada, 1981-2000Leslie A Gaudette
Chronic Disease Management and Control Division, Centre for Chronic Disease Prevention and Control, Health Canada, Ottawa, ON
Can J Public Health 95:336-40. 2004..To evaluate the rate and magnitude of change in surgical practice for breast cancer in Canada in relation to publication dates of clinical trials and consensus conferences...
Postmastectomy radiation therapy: who needs it?Ivo A Olivotto
J Clin Oncol 22:4237-9. 2004
Clinical practice guidelines for the care and treatment of breast cancer: 16. Locoregional post-mastectomy radiotherapyPauline T Truong
BC Cancer Agency-Vancouver Island Centre
CMAJ 170:1263-73. 2004..The final document was approved by the steering committee. SPONSOR: The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer was convened by Health Canada. COMPLETION DATE: November 2003...
Staging reclassification affects breast cancer survivalIvo A Olivotto
J Clin Oncol 21:4467-8. 2003
Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trialJoseph Ragaz
McGill University Health Center, Royal Victoria Hospital, 687 Pine Ave, Montreal, PQ, Canada H3A 1A1
J Natl Cancer Inst 97:116-26. 2005..We report the analysis of data from the 20-year follow-up...
Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological typeWilliam D Foulkes
Departments of Oncology, Sir M B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
Clin Cancer Res 10:2029-34. 2004..The relationship between ER status and other clinical features of hereditary breast cancers has not been well studied...
In regard to Fortin et al., Int J Radiat Oncol Biol Phys 2003;56:1013-1022Ivo A Olivotto
Int J Radiat Oncol Biol Phys 58:1317-8; author reply 1318. 2004
Standardized audiotape versus recorded consultation to enhance informed consent to a clinical trial in breast oncologyThomas F Hack
Faculty of Nursing, University of Manitoba, St Boniface Hospital Research Centre, 351 Tache Avenue, Winnipeg, MB, Canada
Psychooncology 16:371-6. 2007....
Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinomaWilliam D Foulkes
Department of Oncology, McGill University, Montreal, Quebec, Canada
Cancer 98:1569-77. 2003..Therefore, the authors questioned whether the known positive correlation between tumor size and lymph node status also was present in women with BRCA1-related breast carcinomas...
Proceedings of the Consensus Conference on Breast Conservation, April 28 to May 1, 2005, Milan, ItalyGordon F Schwartz
Department of Surgery, Jefferson Medical College, Philadelphia, Pennsylvania 19107-4305, USA
Cancer 107:242-50. 2006
Consensus conference on breast conservationGordon F Schwartz
J Am Coll Surg 203:198-207. 2006
