Olena Morozova

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. pmc A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data
    Olena Morozova
    Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
    PLoS ONE 3:e3205. 2008
  2. doi request reprint Applications of new sequencing technologies for transcriptome analysis
    Olena Morozova
    BC Cancer Agency, Genome Sciences Center, Vancouver, BC V5Z 4S6, Canada
    Annu Rev Genomics Hum Genet 10:135-51. 2009
  3. doi request reprint System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma
    Olena Morozova
    Genome Sciences Centre, BC Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada
    Clin Cancer Res 16:4572-82. 2010
  4. pmc LNCaP Atlas: gene expression associated with in vivo progression to castration-recurrent prostate cancer
    Tammy L Romanuik
    Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    BMC Med Genomics 3:43. 2010
  5. doi request reprint Applications of next-generation sequencing technologies in functional genomics
    Olena Morozova
    BC Cancer Agency Genome Sciences Centre, Vancouver, BC, Canada
    Genomics 92:255-64. 2008
  6. doi request reprint Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance
    Michael D O'Connor
    Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada
    Exp Hematol 39:866-79.e1. 2011
  7. pmc Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal
    Pavle Vrljicak
    Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 1L3
    Physiol Genomics 40:150-7. 2010
  8. doi request reprint From cytogenetics to next-generation sequencing technologies: advances in the detection of genome rearrangements in tumors
    Olena Morozova
    BC Cancer Agency Genome Sciences Centre, Suite 100 570 West 7th Avenue, Vancouver, BC V5Z4S6, Canada
    Biochem Cell Biol 86:81-91. 2008
  9. pmc Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression
    Alireza Baradaran-Heravi
    Department of Medical Genetics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    Hum Mol Genet 21:2572-87. 2012

Collaborators

Detail Information

Publications9

  1. pmc A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data
    Olena Morozova
    Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
    PLoS ONE 3:e3205. 2008
    ..Most analyses of SAGE data aimed at identifying co-expressed genes have been accomplished using various versions of clustering approaches that often result in a number of false positives...
  2. doi request reprint Applications of new sequencing technologies for transcriptome analysis
    Olena Morozova
    BC Cancer Agency, Genome Sciences Center, Vancouver, BC V5Z 4S6, Canada
    Annu Rev Genomics Hum Genet 10:135-51. 2009
    ....
  3. doi request reprint System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma
    Olena Morozova
    Genome Sciences Centre, BC Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada
    Clin Cancer Res 16:4572-82. 2010
    ..NB tumor-initiating cells (TICs), isolated from metastases and primary tumors, may escape treatment and contribute to tumor relapse. New therapies that target the TICs may therefore prevent or treat tumor recurrences...
  4. pmc LNCaP Atlas: gene expression associated with in vivo progression to castration-recurrent prostate cancer
    Tammy L Romanuik
    Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    BMC Med Genomics 3:43. 2010
    ..There is no cure for castration-recurrent prostate cancer (CRPC) and the mechanisms underlying this stage of the disease are unknown...
  5. doi request reprint Applications of next-generation sequencing technologies in functional genomics
    Olena Morozova
    BC Cancer Agency Genome Sciences Centre, Vancouver, BC, Canada
    Genomics 92:255-64. 2008
    ..This review discusses applications of next-generation sequencing technologies in functional genomics research and highlights the transforming potential these technologies offer...
  6. doi request reprint Retinoblastoma-binding proteins 4 and 9 are important for human pluripotent stem cell maintenance
    Michael D O'Connor
    Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, BC, Canada
    Exp Hematol 39:866-79.e1. 2011
    ..Here we sought to identify new candidate PS cell regulators to facilitate future improvements in their generation, expansion, and differentiation...
  7. pmc Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal
    Pavle Vrljicak
    Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 1L3
    Physiol Genomics 40:150-7. 2010
    ..These results identify molecular signatures that distinguish different phases of early heart valve formation allowing gene expression and function to be further investigated...
  8. doi request reprint From cytogenetics to next-generation sequencing technologies: advances in the detection of genome rearrangements in tumors
    Olena Morozova
    BC Cancer Agency Genome Sciences Centre, Suite 100 570 West 7th Avenue, Vancouver, BC V5Z4S6, Canada
    Biochem Cell Biol 86:81-91. 2008
    ..We end with a discussion of the potential that next-generation sequencing technologies may offer to the field...
  9. pmc Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression
    Alireza Baradaran-Heravi
    Department of Medical Genetics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    Hum Mol Genet 21:2572-87. 2012
    ..We conclude that the SMARCAL1 annealing helicase buffers fluctuations in gene expression and that alterations in gene expression contribute to the penetrance of SIOD...