Calum Macaulay

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. doi request reprint High throughput image cytometry for detection of suspicious lesions in the oral cavity
    Calum Macaulay
    BC Cancer Agency, Integrative Oncology Department, 675 West 10th Avenue, Vancouver, B C, Canada V5Z1L3
    J Biomed Opt 17:086004-1. 2012
  2. pmc A sequence-based approach to identify reference genes for gene expression analysis
    Raj Chari
    Department of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver, BC, Canada
    BMC Med Genomics 3:32. 2010
  3. pmc Comprehensive serial analysis of gene expression of the cervical transcriptome
    Ashleen Shadeo
    Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 8:142. 2007
  4. pmc Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia
    Ashleen Shadeo
    Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 9:64. 2008
  5. pmc Effect of active smoking on the human bronchial epithelium transcriptome
    Raj Chari
    Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 8:297. 2007
  6. pmc SIGMA: a system for integrative genomic microarray analysis of cancer genomes
    Raj Chari
    Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 7:324. 2006
  7. pmc Canadian Optically-guided approach for Oral Lesions Surgical (COOLS) trial: study protocol for a randomized controlled trial
    Catherine F Poh
    Department of Oral Biological and Medical Science, The University of British Columbia, Wesbrook Mall, Vancouver, Canada
    BMC Cancer 11:462. 2011
  8. pmc A stepwise framework for the normalization of array CGH data
    Mehrnoush Khojasteh
    British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Bioinformatics 6:274. 2005
  9. pmc SIGMA2: a system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
    Raj Chari
    Department of Cancer Genetics and Developmental Biology, BC Cancer Agency Research Centre, Vancouver, BC, Canada
    BMC Bioinformatics 9:422. 2008
  10. pmc MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
    Bryan Chi
    Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Bioinformatics 9:243. 2008

Collaborators

  • Catherine F Poh
  • Miriam P Rosin
  • Gerald Li
  • Martial Guillaud
  • Stephen Lam
  • Raj Chari
  • Wan L Lam
  • Raymond T Ng
  • Bradley P Coe
  • Kim M Lonergan
  • Ashleen Shadeo
  • Ivana K Cecic
  • Bryan Chi
  • Jasenka Matisic
  • Dianne Miller
  • Dirk Van Niekerk
  • Michele Follen
  • Denise M Laronde
  • Mehrnoush Khojasteh
  • Ming Sound Tsao
  • Timothy H W Chan
  • Chang Qi Zhu
  • Larissa A Pikor
  • Ronald J DeLeeuw
  • Ian M Wilson
  • Marie Benetti
  • Tom Ehlen
  • Rebecca Richards-Kortum
  • Emily A Vucic
  • Craig Wedseltoft
  • Andrea Pusic
  • Jennifer Campbell
  • T Greg Hislop
  • Greg Vatcher
  • P Michele Williams
  • Thomas Ehlen
  • Lewei Zhang
  • Jonathan J Davies
  • Anna Chu
  • William W Lockwood
  • Andrew Thomson
  • Devon Macey
  • Rabab K Ward

Detail Information

Publications17

  1. doi request reprint High throughput image cytometry for detection of suspicious lesions in the oral cavity
    Calum Macaulay
    BC Cancer Agency, Integrative Oncology Department, 675 West 10th Avenue, Vancouver, B C, Canada V5Z1L3
    J Biomed Opt 17:086004-1. 2012
    ..4% of the abnormal samples in the test set. These data suggest that quantitative cytology could reduce by more than 85% the number of visually suspect lesions requiring further assessment by biopsy...
  2. pmc A sequence-based approach to identify reference genes for gene expression analysis
    Raj Chari
    Department of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver, BC, Canada
    BMC Med Genomics 3:32. 2010
    ..Alternatively, as sequencing-based technologies provide digital quantitative output, absolute quantification ensues, and reference gene identification becomes more accurate...
  3. pmc Comprehensive serial analysis of gene expression of the cervical transcriptome
    Ashleen Shadeo
    Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 8:142. 2007
    ..In this study we examine the normal cervical tissue transcriptome and investigate the similarities and differences in relation to CIN III by Long-SAGE (L-SAGE)...
  4. pmc Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia
    Ashleen Shadeo
    Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 9:64. 2008
    ..Thoughtful consideration of gene expression changes paralleling the progressive pre invasive neoplastic development will yield insight into the key casual events involved in cervical cancer development...
  5. pmc Effect of active smoking on the human bronchial epithelium transcriptome
    Raj Chari
    Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 8:297. 2007
    ....
  6. pmc SIGMA: a system for integrative genomic microarray analysis of cancer genomes
    Raj Chari
    Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Genomics 7:324. 2006
    ..However, tools for direct mining and analysis of array CGH data are limited. Hence, there is a great need for analytical and display software tailored to cross platform integrative analysis of cancer genomes...
  7. pmc Canadian Optically-guided approach for Oral Lesions Surgical (COOLS) trial: study protocol for a randomized controlled trial
    Catherine F Poh
    Department of Oral Biological and Medical Science, The University of British Columbia, Wesbrook Mall, Vancouver, Canada
    BMC Cancer 11:462. 2011
    ....
  8. pmc A stepwise framework for the normalization of array CGH data
    Mehrnoush Khojasteh
    British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Bioinformatics 6:274. 2005
    ..The purpose of this work is to establish a framework for correcting the systematic sources of variation in high density CGH array images, while maintaining the true biological variations...
  9. pmc SIGMA2: a system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
    Raj Chari
    Department of Cancer Genetics and Developmental Biology, BC Cancer Agency Research Centre, Vancouver, BC, Canada
    BMC Bioinformatics 9:422. 2008
    ..However, software packages to handle, analyze, and visualize data from these multiple 'omics disciplines have not been adequately developed...
  10. pmc MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
    Bryan Chi
    Department of Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, Vancouver, BC, Canada
    BMC Bioinformatics 9:243. 2008
    ..Due to the differences in data types it is difficult to conduct parallel analysis of multiple datasets from diverse platforms...
  11. ncbi request reprint A magic wand for the community dental office? Observations from the British Columbia Oral Cancer Prevention Program
    Denise M Laronde
    BC Oral Cancer Prevention Program, BC Cancer Control Research Centre, 675 West 10th Avenue, Vancouver, BC V5Z 1L3
    J Can Dent Assoc 73:607-9. 2007
  12. ncbi request reprint Visualization and other emerging technologies as change makers for oral cancer prevention
    Miriam P Rosin
    BC Oral Cancer Prevention Program, BC Cancer Agency, Cancer Control Research Centre, Vancouver, BC, Canada
    Ann N Y Acad Sci 1098:167-83. 2007
    ..A critical development for the translation of this technology into community settings is the establishment of an effective methodology for education and training of health practitioners on the front lines...
  13. ncbi request reprint Oral cancer screening in a high-risk underserved community--Vancouver Downtown Eastside
    Catherine F Poh
    Faculty of Dentistry, University of British Columbia UBC, Vancouver, B C, Canada V6T
    J Health Care Poor Underserved 18:767-78. 2007
    ..They support a future expansion of this initiative to create a more comprehensive strategy for outreach to this underserved community that extends to screening, diagnostic work-up, and treatment...
  14. pmc Double staining cytologic samples with quantitative Feulgen-thionin and anti-Ki-67 immunocytochemistry as a method of distinguishing cells with abnormal DNA content from normal cycling cells
    Gerald Li
    Integrative Oncology Department, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada
    Anal Quant Cytol Histol 34:273-84. 2012
    ....
  15. ncbi request reprint Direct fluorescence visualization of clinically occult high-risk oral premalignant disease using a simple hand-held device
    Catherine F Poh
    BC Cancer Agency, Cancer Control Research Program, Vancouver, British Columbia V5Z 1L3, Canada
    Head Neck 29:71-6. 2007
    ..A considerable proportion of oral cancer and precancer is not clinically apparent and could contribute significantly to the late diagnosis and high mortality of oral cancer. A simple method to identify such occult change is needed...
  16. pmc Automated sputum cytometry for detection of intraepithelial neoplasias in the lung
    Gerald Li
    Integrative Oncology Department, BC Cancer Research Centre, Vancouver, Canada
    Anal Cell Pathol (Amst) 35:187-201. 2012
    ..Our novel sputum biomarker, the Combined Score (CS), uses automated image cytometric analysis of ploidy and nuclear morphology to detect subtle intraepithelial changes that often precede lung tumours...
  17. doi request reprint Technologies supporting analytical cytology: clinical, research and drug discovery applications
    Ivana K Cecic
    Integrative Oncology Department, BC Cancer Research Centre, Vancouver, BC, Canada
    J Biophotonics 5:313-26. 2012
    ....