Research Topics
| Viviane LimaSummaryAffiliation: British Columbia Country: Canada Publications
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Detail Information
Publications
Emergence of drug resistance is associated with an increased risk of death among patients first starting HAARTRobert S Hogg
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
PLoS Med 3:e356. 2006..The objective of this study was to determine the impact of the emergence of drug-resistance mutations on survival among persons initiating HAART...
Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapyViviane D Lima
BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
AIDS 21:685-92. 2007..To characterize the temporal changes in mortality and life expectancy among HIV-positive individuals initiating antiretroviral therapy in British Columbia, Canada, from 1993 to 2004...
Computerized adaptive testing in back pain: validation of the CAT-5D-QOLJacek A Kopec
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada
Spine (Phila Pa 1976) 33:1384-90. 2008..We have conducted an outcome instrument validation study...
Expanded access to highly active antiretroviral therapy: a potentially powerful strategy to curb the growth of the HIV epidemicViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, British Columbia, Canada
J Infect Dis 198:59-67. 2008..These results provide powerful additional motivation to accelerate the roll out of HAART programs aggressively targeting those in medical need, both for their own benefit and as a means of decreasing new HIV infections...
Development and validation of a composite programmatic assessment tool for HIV therapyViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
PLoS ONE 7:e47859. 2012..We hypothesized that non-compliance would be associated with the highest probability of mortality...
Assessing the effectiveness of antiretroviral regimens in cohort studies involving HIV-positive injection drug usersViviane Dias Lima
BC Centre for Excellence in HIV AIDS, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
AIDS 26:1491-500. 2012..We compared HAART regimens containing efavirenz and boosted atazanavir. We developed logistic regression models using different techniques to control for potential confounders...
HIV/AIDS in Vancouver, British Columbia: a growing epidemicColin W McInnes
British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, 608 1081 Burrard Street, Vancouver, British Columbia, V6Z 1Y6, Canada
Harm Reduct J 6:5. 2009..These results suggest that HIV infection is having a relatively large impact in Vancouver and that evidence-based prevention and harm reduction strategies should be expanded...
Trends in reported AIDS defining illnesses (ADIs) among participants in a universal antiretroviral therapy program: an observational studySiavash Jafari
British Columbia Centre for Excellence in HIV AIDS, St, Paul s Hospital, Vancouver, Canada
AIDS Res Ther 8:31. 2011..abstract:..
Migration adversely affects antiretroviral adherence in a population-based cohort of HIV/AIDS patientsViviane Lima
HIV AIDS Drug Treatment Program, British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6
Soc Sci Med 68:1044-9. 2009..These results suggest that proactive strategies are needed to ensure that antiretroviral therapy remains available on a continued basis to highly migrant populations...
Expanding HAART treatment to all currently eligible individuals under the 2008 IAS-USA Guidelines in British Columbia, CanadaViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
PLoS ONE 5:e10991. 2010..Here, we explored the potential impact of different HAART coverage scenarios, based on the new guidelines, on the HIV-related incidence, morbidity and mortality in BC, Canada...
The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over timeViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada
J Acquir Immune Defic Syndr 50:529-36. 2009..To characterize the impact of longitudinal adherence on survival in drug-naive individuals starting currently recommended highly active antiretroviral therapy (HAART) regimens...
Risk of viral failure declines with duration of suppression on highly active antiretroviral therapy irrespective of adherence levelViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
J Acquir Immune Defic Syndr 55:460-5. 2010..To model the effect of adherence and duration of viral suppression on the risk of viral rebound...
Regional and temporal trends in migration among people living with HIV/AIDS in British Columbia, 1993-2005Viviane D Lima
HIV AIDS Drug Treatment Program, BC Centre for Excellence in HIV AIDS, 608 1081 Burrard Street, Vancouver, BC V6Z 1Y6
Can J Public Health 101:44-9. 2010..To examine regional and temporal trends in migration among patients receiving HIV treatment in British Columbia (BC)...
The effect of adherence on the association between depressive symptoms and mortality among HIV-infected individuals first initiating HAARTViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 608 1081 Burrard Street, Vancouver, British Columbia, Canada
AIDS 21:1175-83. 2007..To determine the impact of depressive symptoms on mortality among HIV/AIDS patients first initiating HAART and the potential role of patient adherence as a confounder and effect modifier in this association...
Epidemiology of antiretroviral multiclass resistanceViviane D Lima
St Paul s Hospital, 1081 Burrard Street, Room 608, Vancouver, British Columbia V6Z 1Y6, Canada
Am J Epidemiol 172:460-8. 2010....
Differential impact of adherence on long-term treatment response among naive HIV-infected individualsViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
AIDS 22:2371-80. 2008....
Expanded highly active antiretroviral therapy coverage among HIV-positive drug users to improve individual and public health outcomesJulio S G Montaner
BC Centre for Excellence in HIV AIDS, Providence Health Care, Vancouver, British Columbia, Canada
J Acquir Immune Defic Syndr 55:S5-9. 2010....
Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detectionVikram S Gill
BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, British Columbia, Canada
Clin Infect Dis 50:98-105. 2010....
Lopinavir/ritonavir pharmacokinetics in a substitution of high-dose soft-gelatin capsule to tablet formulationMark W Hull
Canadian HIV Trials Network, Vancouver, Canada
J Clin Pharmacol 49:155-61. 2009....
Effect of baseline CD4 cell counts on the clinical significance of short-term immunologic response to antiretroviral therapy in individuals with virologic suppressionDavid M Moore
Division of Epidemiology and Population Health, British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
J Acquir Immune Defic Syndr 52:357-63. 2009..However, the effects of immunologic responses, whether measured as CD4 count changes from baseline or CD4 counts at follow-up, in patients with virologic suppression, have not been clearly established...
Increased resilience to the development of drug resistance with modern boosted protease inhibitor-based highly active antiretroviral therapyViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, British Columbia, Canada
J Infect Dis 198:51-8. 2008..We explore the temporal and regimen-specific changes of HIV-1 drug resistance in a large cohort of antiretroviral-naive individuals starting highly active antiretroviral therapy (HAART)...
Determinants of nevirapine hypersensitivity and its effect on the association between hepatitis C status and mortality in antiretroviral drug-naive HIV-positive patientsElizabeth Phillips
British Columbia Centre for Excellence in HIV AIDS, Providence Healthcare, St Paul s Hospital, 667 1081 Burrard Street, Vancouver, BC, Canada
AIDS 21:1561-8. 2007....
Increased reporting of detectable plasma HIV-1 RNA levels at the critical threshold of 50 copies per milliliter with the Taqman assay in comparison to the Amplicor assayViviane Lima
British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
J Acquir Immune Defic Syndr 51:3-6. 2009..5, with a particular focus on the most clinically relevant region near the lower limit of quantification...
Impact of neighborhood-level socioeconomic status on HIV disease progression in a universal health care settingRuth Joy
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
J Acquir Immune Defic Syndr 47:500-5. 2008....
Silent mutations are selected in HIV-1 reverse transcriptase and affect enzymatic efficiencyP Richard Harrigan
BC Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada
AIDS 22:2501-8. 2008..Missense mutations in HIV-1 reverse transcriptase are frequently selected in response to therapy; we examined whether silent mutations were also selected for by HIV therapy...
Prevalence of bone mineral density abnormalities and related risk factors in an ambulatory HIV clinic populationSilvia Guillemi
British Columbia Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada
J Clin Densitom 13:456-61. 2010..Lower BMI was independently associated with low BMD. No correlation was found between abnormal BMD and cumulative exposure to any antiretroviral agents...
Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based studyJulio S G Montaner
British Columbia Centre for Excellence in HIV AIDS, Providence Health Care, Vancouver, BC, Canada
Lancet 376:532-9. 2010..We aimed to estimate the association between plasma HIV-1 viral load, HAART coverage, and number of new cases of HIV in the population of a Canadian province...
Association between HIV-1 RNA level and CD4 cell count among untreated HIV-infected individualsViviane D Lima
British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, 667 1081 Burrard St, Vancouver, BC, V6Z 1Y6 Canada
Am J Public Health 99:S193-6. 2009..We examined the significance of plasma HIV-1 RNA levels (or viral load alone) in predicting CD4 cell decline in untreated HIV-infected individuals...
Factors associated with virological suppression among HIV-positive individuals on highly active antiretroviral therapy in a multi-site Canadian cohortA M Cescon
British Columbia Centre for Excellence in HIV AIDS, Vancouver, Canada
HIV Med 12:352-60. 2011..The aim of the study was to evaluate time to virological suppression in a cohort of individuals who started highly active antiretroviral therapy (HAART), and to explore the factors associated with suppression...
Epidemiology of treatment failure: a focus on recent trendsMark W Hull
BC Centre for Excellence in HIV AIDS, Simon Fraser University, Vancouver, British Columbia, Canada
Curr Opin HIV AIDS 4:467-73. 2009..This review will highlight recent trends in treatment failure and virologic resistance in the developed world and resource-limited settings...
Does ratification of human-rights treaties have effects on population health?Alexis Palmer
Faculty of Health Sciences, Simon Fraser University, Vancouver, BC, Canada
Lancet 373:1987-92. 2009....
Presenting plasma HIV RNA level and rate of CD4 T-cell declineViviane D Lima
JAMA 297:805-6; author reply 806-7. 2007
Is nevirapine-based therapy discontinuation in hepatitis C co-infected patients a more important mortality determinant than hypersensitivity: authors' replyElizabeth Phillips
AIDS 22:548-9. 2008
