Mel Krajden

Summary

Affiliation: British Columbia
Country: Canada

Publications

  1. ncbi Pooled nucleic acid testing increases the diagnostic yield of acute HIV infections in a high-risk population compared to 3rd and 4th generation HIV enzyme immunoassays
    Mel Krajden
    Clinical Prevention Services, BC Centre for Disease Control, 655 West 12th Ave, Vancouver, BC V5Z 4R4, Canada Faculty of Medicine, University of British Columbia, 2194 Health Sciences Mall, Vancouver, BC V6 T 1Z3, Canada Public Health Microbiology and Reference Laboratory, BC Centre for Disease Control, 655 West 12th Ave Vancouver, BC V5Z 4R4, Canada Electronic address
    J Clin Virol 61:132-7. 2014
  2. pmc Detection of Early Sero-Conversion HIV Infection Using the INSTI HIV-1 Antibody Point-of-Care Test
    Darrel Cook
    British Columbia Centre for Disease Control, 655 West 12 Avenue, Vancouver, BC, V5Z 4R4, Canada
    Open AIDS J 4:176-9. 2010
  3. ncbi Assessment of HPV 16 and HPV 18 antibody responses by pseudovirus neutralization, Merck cLIA and Merck total IgG LIA immunoassays in a reduced dosage quadrivalent HPV vaccine trial
    Mel Krajden
    British Columbia Centre for Disease Control, 655 West 12th Avenue, Vancouver, Canada Faculty of Medicine, University of British Columbia, 317 2194 Health Sciences Mall, Vancouver, Canada Electronic address
    Vaccine 32:624-30. 2014
  4. doi GBV-C/hepatitis G virus infection and non-Hodgkin lymphoma: a case control study
    Mel Krajden
    British Columbia Centre for Disease Control, Vancouver, BC, Canada
    Int J Cancer 126:2885-92. 2010
  5. pmc Prevalence of human papillomavirus 16 and 18 neutralizing antibodies in prenatal women in British Columbia
    Mel Krajden
    BC Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC V5Z 4R4, Canada
    Clin Vaccine Immunol 16:1840-3. 2009
  6. pmc Health care costs associated with hepatitis C: a longitudinal cohort study
    Mel Krajden
    BC Centre for Disease Control, Vancouver, British Columbia
    Can J Gastroenterol 24:717-26. 2010
  7. pmc Human papillomavirus 16 (HPV 16) and HPV 18 antibody responses measured by pseudovirus neutralization and competitive Luminex assays in a two- versus three-dose HPV vaccine trial
    Mel Krajden
    BC Centre for Disease Control, 655 West 12th Avenue, Vancouver BC V5Z 4R4, Canada
    Clin Vaccine Immunol 18:418-23. 2011
  8. pmc Evaluation of the core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C virus infection
    Mel Krajden
    British Columbia Center for Disease Control, 655 W 12th Ave, Vancouver, BC V5Z4R4, Canada
    J Clin Microbiol 42:4054-9. 2004
  9. pmc Qualitative detection of hepatitis C virus RNA: comparison of analytical sensitivity, clinical performance, and workflow of the Cobas Amplicor HCV test version 2.0 and the HCV RNA transcription-mediated amplification qualitative assay
    Mel Krajden
    British Columbia Centers of Disease Control, Vancouver, Canada
    J Clin Microbiol 40:2903-7. 2002
  10. pmc Factors associated with spontaneous clearance of hepatitis C virus among illicit drug users
    Jason Grebely
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada
    Can J Gastroenterol 21:447-51. 2007

Detail Information

Publications58

  1. ncbi Pooled nucleic acid testing increases the diagnostic yield of acute HIV infections in a high-risk population compared to 3rd and 4th generation HIV enzyme immunoassays
    Mel Krajden
    Clinical Prevention Services, BC Centre for Disease Control, 655 West 12th Ave, Vancouver, BC V5Z 4R4, Canada Faculty of Medicine, University of British Columbia, 2194 Health Sciences Mall, Vancouver, BC V6 T 1Z3, Canada Public Health Microbiology and Reference Laboratory, BC Centre for Disease Control, 655 West 12th Ave Vancouver, BC V5Z 4R4, Canada Electronic address
    J Clin Virol 61:132-7. 2014
    ..We compared a 3rd generation (gen) and two 4th gen HIV enzyme immunoassays (EIA) to pooled nucleic acid testing (PNAT) for the identification of pre- and early seroconversion acute HIV infection (AHI)...
  2. pmc Detection of Early Sero-Conversion HIV Infection Using the INSTI HIV-1 Antibody Point-of-Care Test
    Darrel Cook
    British Columbia Centre for Disease Control, 655 West 12 Avenue, Vancouver, BC, V5Z 4R4, Canada
    Open AIDS J 4:176-9. 2010
    ..Both POC and laboratory-based anti-HIV tests will fail to detect a proportion of infected individuals in the first weeks after infection...
  3. ncbi Assessment of HPV 16 and HPV 18 antibody responses by pseudovirus neutralization, Merck cLIA and Merck total IgG LIA immunoassays in a reduced dosage quadrivalent HPV vaccine trial
    Mel Krajden
    British Columbia Centre for Disease Control, 655 West 12th Avenue, Vancouver, Canada Faculty of Medicine, University of British Columbia, 317 2194 Health Sciences Mall, Vancouver, Canada Electronic address
    Vaccine 32:624-30. 2014
    ..We conclude that the PsV NAb assay is more sensitive than the cLIA, and likely more specific than the TIgG assay. ..
  4. doi GBV-C/hepatitis G virus infection and non-Hodgkin lymphoma: a case control study
    Mel Krajden
    British Columbia Centre for Disease Control, Vancouver, BC, Canada
    Int J Cancer 126:2885-92. 2010
    ..This is the largest case-control study to date associating GBV-C viremia and NHL risk. As GBV-C is known to be transmitted through blood products this may have important implications for blood safety...
  5. pmc Prevalence of human papillomavirus 16 and 18 neutralizing antibodies in prenatal women in British Columbia
    Mel Krajden
    BC Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC V5Z 4R4, Canada
    Clin Vaccine Immunol 16:1840-3. 2009
    ..HPV 16 and 18 NAbs were detected in 183/1,020 (17.9%) and 97/1,020 (9.5%), respectively, and 39 (3.8%) had NAbs to both types. Titers were similar across age strata...
  6. pmc Health care costs associated with hepatitis C: a longitudinal cohort study
    Mel Krajden
    BC Centre for Disease Control, Vancouver, British Columbia
    Can J Gastroenterol 24:717-26. 2010
    ..Disease-specific estimates of medical costs are important for health policy decision making...
  7. pmc Human papillomavirus 16 (HPV 16) and HPV 18 antibody responses measured by pseudovirus neutralization and competitive Luminex assays in a two- versus three-dose HPV vaccine trial
    Mel Krajden
    BC Centre for Disease Control, 655 West 12th Avenue, Vancouver BC V5Z 4R4, Canada
    Clin Vaccine Immunol 18:418-23. 2011
    ..905 for HPV 18. Most of the discordant results were observed at lower cLIA signals. These results suggest that the PsV NAb assay could be a suitable alternative to cLIA for the measurement of postvaccine antibody responses...
  8. pmc Evaluation of the core antigen assay as a second-line supplemental test for diagnosis of active hepatitis C virus infection
    Mel Krajden
    British Columbia Center for Disease Control, 655 W 12th Ave, Vancouver, BC V5Z4R4, Canada
    J Clin Microbiol 42:4054-9. 2004
    ..Qualitative HCV RNA testing remains the present standard for the confirmation of active HCV infection in the diagnostic setting...
  9. pmc Qualitative detection of hepatitis C virus RNA: comparison of analytical sensitivity, clinical performance, and workflow of the Cobas Amplicor HCV test version 2.0 and the HCV RNA transcription-mediated amplification qualitative assay
    Mel Krajden
    British Columbia Centers of Disease Control, Vancouver, Canada
    J Clin Microbiol 40:2903-7. 2002
    ..HCV TMA demonstrated excellent concordance with HCV PCR when clinical samples were tested. However, HCV TMA was more sensitive than HCV PCR, required less time for test result completion, and had a greater throughput...
  10. pmc Factors associated with spontaneous clearance of hepatitis C virus among illicit drug users
    Jason Grebely
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada
    Can J Gastroenterol 21:447-51. 2007
    ..Spontaneous clearance of hepatitis C virus (HCV) occurs in approximately 25% of individuals...
  11. ncbi An association between cytomegalovirus infection and pre-eclampsia: a case-control study and data synthesis
    Fang Xie
    Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada
    Acta Obstet Gynecol Scand 89:1162-7. 2010
    ..Pre-eclampsia shares several similarities with atherosclerotic heart disease. We explored whether, like atherosclerosis, there is a potential link between cytomegalovirus (CMV) infection and pre-eclampsia...
  12. pmc HCV co-infection in HIV positive population in British Columbia, Canada
    Jane A Buxton
    BC Centre for Disease Control, Vancouver, British Columbia
    BMC Public Health 10:225. 2010
    ..This study used a population-based sample of HIV and HCV tested individuals to determine the prevalence of HIV/HCV co-infection, the sequence of virus diagnoses, and demographic and associated risk factors...
  13. pmc Publicly funded pegylated interferon-alpha treatment in British Columbia: disparities in treatment patterns for people with hepatitis C
    Priscilla C Hsu
    British Columbia Centre for Disease Control, University of British Columbia, Vancouver, Canada
    Can J Gastroenterol 22:359-64. 2008
    ..Although treatment may prevent cirrhosis and liver cancer, and improve quality of life, availability is limited...
  14. pmc Protective measures and human antibody response during an avian influenza H7N3 outbreak in poultry in British Columbia, Canada
    Danuta M Skowronski
    BC Centre for Disease Control, Vancouver, BC
    CMAJ 176:47-53. 2007
    ..In 2004 an outbreak of avian influenza of the H7N3 subtype occurred among poultry in British Columbia, Canada. We report compliance with recommended protective measures and associated human infections during this outbreak...
  15. doi Health utilities and psychometric quality of life in patients with early- and late-stage hepatitis C virus infection
    Priscilla C Hsu
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    J Gastroenterol Hepatol 27:149-57. 2012
    ..The purpose of this study was to evaluate HRQOL across the HCV disease spectrum using preference-based (utility) and non-preference-based (psychometric) methods, adjusting for sociodemographic factors and co-morbidity...
  16. doi Patient time costs and out-of-pocket costs in hepatitis C
    Carole A Federico
    Biomedical Ethics Unit, McGill University, Montreal, Quebec, Canada
    Liver Int 32:815-25. 2012
    ..Hepatitis C virus (HCV) infection is associated with substantial costs to patients, their caregivers and society...
  17. doi Immunogenicity of 2 doses of HPV vaccine in younger adolescents vs 3 doses in young women: a randomized clinical trial
    Simon R M Dobson
    Department of Pediatrics, University of British Columbia, Vancouver, Canada
    JAMA 309:1793-802. 2013
    ..Global use of human papillomavirus (HPV) vaccines to prevent cervical cancer is impeded by cost. A 2-dose schedule for girls may be possible...
  18. pmc Towards targeted screening for acute HIV infections in British Columbia
    MALCOLM STEINBERG
    British Columbia Centre for Disease Control, Vancouver, BC, Canada
    J Int AIDS Soc 14:39. 2011
    ..Province-wide HIV testing and surveillance data were analyzed to inform recommendations for targeted use of screening algorithms to detect acute HIV infections...
  19. pmc Targeting screening and social marketing to increase detection of acute HIV infection in men who have sex with men in Vancouver, British Columbia
    Mark Gilbert
    aClinical Prevention Services, British Columbia Centre for Disease Control bFaculty of Medicine, University of British Columbia cBC Public Health Microbiology and Reference Laboratory, British Columbia Centre for Disease Control, Vancouver dFaculty of Health Sciences, Simon Fraser University, Burnaby eHealth Initiative for Men, Vancouver, British Columbia, Canada
    AIDS 27:2649-54. 2013
    ..We examined the impact of targeted pooled nucleic acid amplification testing (NAAT) and social marketing to increase AHI diagnosis among men who have sex with men (MSM) in Vancouver...
  20. ncbi Hepatitis C virus and risk of non-Hodgkin lymphoma in British Columbia, Canada
    John J Spinelli
    BC Cancer Agency, Vancouver, British Columbia, Canada
    Int J Cancer 122:630-3. 2008
    ..The highest risks were associated with diffuse large B-cell lymphoma (OR = 7.3, 95%CI = 2.1-25.0) and marginal zone lymphoma (OR = 6.1, 95%CI = 1.1-33.9). Our results provide further evidence that HCV infection contributes to NHL risk...
  21. pmc Mortality among British Columbians testing for hepatitis C antibody
    Amanda Yu
    BC Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC V5Z 4R4, Canada
    BMC Public Health 13:291. 2013
    ....
  22. doi Age of recipient and number of doses differentially impact human B and T cell immune memory responses to HPV vaccination
    Kinga K Smolen
    Experimental Medicine Program, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    Vaccine 30:3572-9. 2012
    ..Our data indicate that rational design of vaccines has to be tailored according to the desired induction of B and/or T cell memory...
  23. ncbi Chlamydia pneumoniae infection in preeclampsia
    Fang Xie
    Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada
    Hypertens Pregnancy 29:468-77. 2010
    ..We examined whether, like atherosclerosis, preeclampsia is associated with infection with Chlamydia pneumoniae (C. pneumoniae)...
  24. pmc Feasibility of self-collection of specimens for human papillomavirus testing in hard-to-reach women
    Gina Ogilvie
    British Columbia Centre for Disease Control, Vancouver, BC
    CMAJ 177:480-3. 2007
    ..05). This difference suggests that self-collection of specimens for HPV testing is a feasible method to reach women who have not previously participated in cervical cancer screening programs...
  25. pmc Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses
    Danuta M Skowronski
    Communicable Disease Prevention and Control Service, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 9:e92153. 2014
    ..During the 2012-13 season, however, detailed genotypic and phenotypic characterization shows that low VE was instead related to mutations in the egg-adapted H3N2 vaccine strain rather than antigenic drift in circulating viruses...
  26. doi Prevalence and risk factors for neutralizing antibodies to human papillomavirus types 16 and 18 in HIV-positive men who have sex with men
    Rachna Sharma
    Department of Medicine, University of California, San Francisco, San Francisco, CA Department of Public Health, East Carolina University Greenville, NC British Columbia Centre for Disease Control Public Health Microbiology and Reference Laboratory, BC Centre for Disease Control, Vancouver, British Columbia, Canada Department of Epidemiology and Biostatistics, University of California, San Francisco and Department of Pathology, University of California, San Francisco
    J Acquir Immune Defic Syndr 64:479-87. 2013
    ..However, little is known about the prevalence of and risk factors for neutralizing antibody seropositivity to HPV-16 or HPV-18, a key measure of previous exposure to these types...
  27. ncbi Hepatitis C infection among pregnant women in British Columbia: reported prevalence and critical appraisal of current prenatal screening methods
    Audrey Blasig
    School of Population and Public Health, University of British Columbia, Vancouver, BC
    Can J Public Health 102:98-102. 2011
    ..The purpose of this study was to determine the overall prevalence rate, age and geographic distribution of reported HCV infection among pregnant women in BC, and compare results to a previously conducted anonymous seroprevalence survey...
  28. doi Does cirrhosis affect quality of life in hepatitis C virus-infected patients?
    Priscilla C Hsu
    British Columbia Centre for Disease Control, Vancouver, BC, Canada
    Liver Int 29:449-58. 2009
    ..Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and is associated with impairments in health-related quality of life...
  29. pmc Longitudinal analysis of genotype distribution of influenza A virus from 2003 to 2005
    Annie Mak
    BC Centre for Disease Control, 655 W12th Ave, Vancouver, BC V5Z 4R4, Canada
    J Clin Microbiol 44:3583-8. 2006
    ..Our findings indicate that genotype determination promises to be a rapid approach for detecting new strains of influenza A viruses in a population...
  30. pmc A randomized controlled trial of Human Papillomavirus (HPV) testing for cervical cancer screening: trial design and preliminary results (HPV FOCAL Trial)
    Gina S Ogilvie
    Department of Family Practice, University of British Columbia, Vancouver, Canada
    BMC Cancer 10:111. 2010
    ....
  31. pmc Capacity enhancement of hepatitis C virus treatment through integrated, community-based care
    Warren D Hill
    British Columbia Centre for Disease Control, Vancouver, Canada
    Can J Gastroenterol 22:27-32. 2008
    ..Treatment outcomes are reported for a subset of individuals undergoing antiviral therapy at four project sites...
  32. ncbi Using centralized laboratory data to monitor trends in herpes simplex virus type 1 and 2 infection in British Columbia and the changing etiology of genital herpes
    Mark Gilbert
    Division of STI HIV Prevention and Control, BC Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC V5Z 4R4
    Can J Public Health 102:225-9. 2011
    ..We used centralized laboratory data to describe trends in viral identifications of genital HSV in BC and assess the utility of these data for ongoing population surveillance...
  33. pmc Modeling control strategies of respiratory pathogens
    Babak Pourbohloul
    Division of Mathematical Modeling, University of British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Emerg Infect Dis 11:1249-56. 2005
    ..Contact network epidemiology can provide valuable quantitative input to public health decisionmaking, even before a pathogen is well characterized...
  34. ncbi The prevalence of gestational diabetes mellitus and glucose abnormalities in pregnant women with hepatitis C virus infection in British Columbia
    Michelle C Buresi
    Division of Gastroenterology, University of British Columbia, Vancouver, BC
    J Obstet Gynaecol Can 32:935-41. 2010
    ..The aim of this study was to compare the prevalence of GDM and impaired glucose tolerance (IGT) of pregnancy between women infected with HCV and the general population of British Columbia screened for GDM...
  35. ncbi Hepatitis C virus reinfection in injection drug users
    Jason Grebely
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Hepatology 44:1139-45. 2006
    ..23; 95% CI, 0.10-0.51, P < .001). In conclusion, individuals with clearance of HCV infection may have a lower risk of acquiring HCV than individuals who have never been infected, despite ongoing exposure to HCV...
  36. pmc Human illness from avian influenza H7N3, British Columbia
    S Aleina Tweed
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Emerg Infect Dis 10:2196-9. 2004
    ..Surveillance identified two persons with confirmed avian influenza infection. Symptoms included conjunctivitis and mild influenzalike illness...
  37. doi Women's intentions to receive cervical cancer screening with primary human papillomavirus testing
    Gina S Ogilvie
    Department of Family Practice and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada British Columbia Centre for Disease Control, Vancouver, BC, Canada
    Int J Cancer 133:2934-43. 2013
    ..Use of primary HPV testing may optimize the screening paradigm, but programs should ensure robust planning and education to mitigate any negative impact on screening attendance rates. ..
  38. ncbi Mumps virus detection during an outbreak in a highly unvaccinated population in British Columbia
    Kennard E Tan
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC
    Can J Public Health 102:47-50. 2011
    ..In British Columbia, mumps circulated in a predominantly unvaccinated population in 2008. We compared laboratory findings between the different vaccination groups and assessed the period of mumps viral detection after onset of parotitis...
  39. ncbi Methadone use in relation to hepatitis C virus testing in British Columbia
    Jane A Buxton
    BC Centre for Disease Control, Vancouver, BC
    Can J Public Health 101:491-4. 2010
    ..We examined methadone use among a large cohort of individuals undergoing serologic testing for hepatitis C virus (HCV) infection...
  40. pmc Coordinated response to SARS, Vancouver, Canada
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada
    Emerg Infect Dis 12:155-8. 2006
    ..Baseline preparedness for pandemic threats may account for the absence of sustained transmission and fewer cases of SARS in Vancouver...
  41. pmc Self-collected versus clinician-collected sampling for sexually transmitted infections: a systematic review and meta-analysis protocol
    Darlene Taylor
    BC Centre for Disease Control, 655 West 12th Avenue, Vancouver, BC V5Z 4R4, Canada
    Syst Rev 2:93. 2013
    ....
  42. doi A sentinel platform to evaluate influenza vaccine effectiveness and new variant circulation, Canada 2010-2011 season
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Provincial Health Services Authority, Vancouver, Canada
    Clin Infect Dis 55:332-42. 2012
    ..Interim analysis from the community-based sentinel surveillance system showed circulating H3N2 variants and suboptimal vaccine effectiveness (VE), assessed here for the entire season's data set...
  43. ncbi Levels of antibodies against cytomegalovirus and Chlamydophila pneumoniae are increased in early onset pre-eclampsia
    Peter von Dadelszen
    Department of Obstetrics and Gynaecology, Children s and Women s Health Centre of British Columbia, University of British Columbia, 2H30 4500 Oak Street, Vancouver, BC, Canada V6H 3N1
    BJOG 110:725-30. 2003
    ..Could reactivated chronic infection be both a trigger for these differential maternal responses to the same underlying pathology and a link between pre-eclampsia and its attendant lifelong risks of atherosclerosis?..
  44. ncbi Variability of hepatitis B testing in British Columbian ESRD patients: the case to focus on implementation of guidelines
    Monica Beaulieu
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Kidney Dis 52:939-46. 2008
    ..Hepatitis B virus (HBV) immunization protocols are routinely followed in dialysis units. Recommendations for retesting and booster dose administration are variable and less well known...
  45. ncbi The Genome sequence of the SARS-associated coronavirus
    Marco A Marra
    British Columbia Cancer Agency BCCA Genome Sciences Centre, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada
    Science 300:1399-404. 2003
    ....
  46. pmc Impact of universal preadolescent vaccination against hepatitis B on antenatal seroprevalence of hepatitis B markers in British Columbia women
    Meenakshi Dawar
    First Nations and Inuit Health Branch, Medical Programs, Pacific Region, Health Canada, Vancouver, BC
    CMAJ 168:703-4. 2003
    ..1% (compared with 41.4% for the entire sample) and the geometric mean titre was 34.9 IU/mL (compared with 0.6-0.8 IU/mL for the older groups [p < 0.001])...
  47. doi Uptake, benefits of and barriers to safer crack use kit (SCUK) distribution programmes in Victoria, Canada--a qualitative exploration
    Andrew Ivsins
    Department of Sociology, University of Victoria, Victoria, BC, Canada
    Int J Drug Policy 22:292-300. 2011
    ..This study explored uptake and benefits of, barriers to, and possible improvements to two recently implemented SCUK distribution programme in Victoria, Canada...
  48. ncbi SARS: a quality management test of our public health safety net
    Ron Zapp
    BC Centre for Disease Control, 655 W 12th Ave, Vancouver, British Columbia, Canada V5Z 4R4
    Qual Manag Health Care 13:120-9. 2004
    ..All knowledge gained was shared with other organizations around the world. The consensus is that British Columbia was very lucky this time around. This review is part of BCCDC's commitment to fighting emerging infectious diseases...
  49. pmc Novel avian influenza H7N3 strain outbreak, British Columbia
    Martin Hirst
    British Columbia Cancer Agency BCCA Genome Sciences Centre, Vancouver, British Columbia, Canada
    Emerg Infect Dis 10:2192-5. 2004
    ..This insertion likely occurred by recombination between the hemagglutination and matrix genes in the LPAI virus...
  50. ncbi Parvovirus B19 in an immunocompetent adult patient with acute liver failure: an underdiagnosed cause of acute non-A-E viral hepatitis
    J Kee Ho
    Department of Medicine, University of British Columbia, Vancouver
    Can J Gastroenterol 19:161-2. 2005
    ..Parvovirus B19 may be the causative agent in some adult cases of acute non-A-E viral hepatitis and acute liver failure...
  51. ncbi West Nile virus finally debuts in British Columbia 10 years after its introduction to North America
    Muhammad Morshed
    Public Health Microbiology and Reference Laboratory, BC Centre for Disease Control, Vancouver, Canada
    Vector Borne Zoonotic Dis 11:1221-4. 2011
    ..Various factors may have contributed to the 10-year delay in the spread of WNv to BC, including regional weather conditions and unique topography...
  52. ncbi Acute nosocomial HCV infection detected by NAT of a regular blood donor
    Bryce Larke
    Edmonton Blood Center, Canadian Blood Services, Edmonton, Alberta, Canada
    Transfusion 42:759-65. 2002
    ..He was a regular donor with none of the commonly reported risk factors for HCV infection...
  53. ncbi Hepatitis C, illicit drug use and public health: does Canada really have a viable plan?
    Benedikt Fischer
    Centre for Addiction and Mental Health, Toronto, ON
    Can J Public Health 97:485-8. 2006
    ..In order to reduce the HCV disease burden, Canada needs to reconsider the scope, delivery and resourcing of both preventive and treatment interventions targeting the primary risk population of illicit drug users...
  54. ncbi Identification of severe acute respiratory syndrome in Canada
    Susan M Poutanen
    Toronto Medical Laboratories and Mount Sinai Hospital Department of Microbiology, Toronto, Canada
    N Engl J Med 348:1995-2005. 2003
    ..This report summarizes the initial epidemiologic findings, clinical description, and diagnostic findings that followed the identification of SARS in Canada...
  55. ncbi Successful HCV genotyping of previously failed and low viral load specimens using an HCV RNA qualitative assay based on transcription-mediated amplification in conjunction with the line probe assay
    Lorraine Comanor
    1801 Waverley Street, Palo Alto, CA 94301, USA
    J Clin Virol 28:14-26. 2003
    ..The Bayer HCV RNA Qualitative assay (HCV TMA), with a limit of detection of approximately 5-10 IU/ml, is more sensitive than other commercial assays...
  56. pmc Injection drug use and the hepatitis C virus: considerations for a targeted treatment approach--the case study of Canada
    Benedikt Fischer
    Department of Public Health Sciences, University of Toronto, Ontario, Canada
    J Urban Health 81:428-47. 2004
    ..The article concludes that treatment of HCV-infected illicit drug users is both feasible and may be necessary to reduce transmission and adverse outcomes in this high-risk population...
  57. pmc Monitoring of hepatitis C virus quasispecies in chronic infection by matrix-assisted laser desorption ionization-time of flight mass spectrometry mutation detection
    Carmen Yea
    Metabolism Research Program, The Hospital for Sick Children, Toronto, Canada
    J Clin Microbiol 45:1053-7. 2007
    ..We also used the mass spectrometry method in the clinical follow-up of a chronically infected patient over a 5-year period...
  58. pmc Problems with the fast-check HIV rapid test kits
    Michael L Rekart
    CMAJ 167:119. 2002