Tiffany W Chow
Affiliation: Baycrest Centre for Geriatric Care
- Incorporating new diagnostic schemas, genetics, and proteinopathy into the evaluation of frontotemporal degenerationTiffany W Chow
Baycrest Rotman Research Institute, 3560 Bathurst Street, 8th Floor Brain Health Complex, Toronto, ON M6A 2E1, Canada
Continuum (Minneap Minn) 19:438-56. 2013..Neurologists, neuropsychologists, and speech pathologists are particularly involved in the diagnosis and recognition of etiologies for patients with deficits in frontal lobe function and language...
- Overlap in frontotemporal atrophy between normal aging and patients with frontotemporal dementiasTiffany W Chow
Division of Neurology, Department of Medicine, University of Toronto, Toronto, Canada
Alzheimer Dis Assoc Disord 22:327-35. 2008..While volumetry identified left-sided atrophy as useful for identifying FTD cases, future studies should determine whether clinicians could make these distinctions on viewing routine diagnostic magnetic resonance imaging scans...
- A case of apathy due to frontotemporal dementia responsive to memantineKira A Links
Baycrest, Rotman Research Institute, Toronto, ON, Canada
Neurocase 19:256-61. 2013..To study the effect of memantine on apathy, a common symptom of behavioral variant frontotemporal dementia (bvFTD)...
- Abnormal network connectivity in frontotemporal dementia: evidence for prefrontal isolationNorman A S Farb
Rotman Research Institute, Baycrest Centre, Toronto, Ontario, Canada
Cortex 49:1856-73. 2013..Recent neuroimaging research also associates FTD with alterations in the brain's intrinsic connectivity networks. The present study explored the relationship between neural network connectivity and specific behavioral symptoms in FTD...
- Trajectories of behavioral disturbance in dementiaTiffany W Chow
Rotman Research Institute of Baycrest, Toronto, ON, Canada
J Alzheimers Dis 31:143-9. 2012..These results support a crescendo-decrescendo trajectory of behavioral symptoms in bvFTD but do not suggest that there is a similar pattern in AD, and further longitudinal data collection is necessary...
- Apathy symptom profile and behavioral associations in frontotemporal dementia vs dementia of Alzheimer typeTiffany W Chow
Baycrest Rotman Research Institute, University of Toronto, Toronto, Ontario M6A 2E1, Canada
Arch Neurol 66:888-93. 2009..Apathy is a common and significant problem in patients with dementia, regardless of its cause. Observations about frontosubcortical circuit syndromes indicate that apathy may have affective, behavioral, or cognitive manifestations...
- Cholinergic pathways and cognition in patients with schizophrenia: a pilot studyTarek K Rajji
Geriatric Mental Health Program, Centre for Addiction and Mental Health, Toronto, Canada
Schizophr Res 139:46-52. 2012..The objective of this study was to evaluate the impact of compromised cholinergic pathways on executive versus non-executive cognitive functions of patients with schizophrenia...
- Fluorodeoxyglucose positron emission tomography in semantic dementia after 6 months of memantine: an open-label pilot studyTiffany W Chow
Division of Neurology, Baycrest, Toronto, Canada
Int J Geriatr Psychiatry 28:319-25. 2013..To follow up on the increases we reported in normalized metabolic activity in salience network hubs from a 2-month open-label study of memantine in frontotemporal dementia (FTD)...
- Whole-brain white matter disruption in semantic and nonfluent variants of primary progressive aphasiaGraeme C Schwindt
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Hum Brain Mapp 34:973-84. 2013..Further, they suggest that differences in the relative sensitivity of diffusion metrics may reflect differences in the nature of underlying white matter pathology in these two subtypes...
- Occupation attributes relate to location of atrophy in frontotemporal lobar degenerationR Nathan Spreng
Rotman Research Institute, Baycrest Centre, Toronto, ON, Canada
Neuropsychologia 48:3634-41. 2010..Alternatively, long-term engagement of activities associated with these occupations contributed to left-lateralized reserve, right-lateralized dysfunction, or both...
- Recollection and familiarity for public events in neurologically intact older adults and two brain-damaged patientsRaluca Petrican
Department of Psychology, University of Toronto, 100 St George Street, Toronto, Ontario M5S 3G3, Canada
Neuropsychologia 48:945-60. 2010..We discuss the present results in the context of neuroanatomical and process-oriented theories of how memories age...
- 100 years after Alzheimer: contemporary neurology practice assessment of referrals for dementiaTiffany W Chow
Department of Medicine, Division of Neurology, University of Toronto, Toronto, Ontario, Canada
Am J Alzheimers Dis Other Demen 23:516-27. 2008..The prevalence of dementia is placing an increased burden on specialists...
- Magnetic resonance imaging in frontotemporal dementia shows subcortical atrophyTiffany W Chow
Department of Medicine, Division of Neurology, University of Toronto, Toronto, Ont, Canada
Dement Geriatr Cogn Disord 26:79-88. 2008..We explored the extent to which subcortical atrophy on structural magnetic resonance imaging may indicate a subcortical contribution to the progression of FTD...
- What are the different initial presentations of frontotemporal dementia?Tiffany W Chow
Department of Medicine, Division of Neurology, University of Toronto, Rotman Research Institute, 3560 Bathurst St, Toronto, ON, M6A 2E1, Canada
J Mol Neurosci 45:710-2. 2011....
- Alzheimer's disease neuropathologic changes in semantic dementiaTiffany W Chow
Rotman Research Institute and Division of Neurology, Baycrest, Toronto, ON, Canada
Neurocase 16:15-22. 2010....
- An international needs assessment of caregivers for frontotemporal dementiaTiffany W Chow
Rotman Research Institute, Baycrest, 3560 Bathurst Street, 8th Floor Brain Health Complex, Toronto, Ontario, M6A 2E1, Canada
Can J Neurol Sci 38:753-7. 2011..To guide development of public awareness and caregiver support resources for frontotemporal dementia (FTD) syndromes...
- MMSE scores decline at a greater rate in frontotemporal degeneration than in ADTiffany W Chow
Rotman Research Institute of Baycrest, University of Toronto Department of Medicine, Division of Neurology, Toronto, Canada
Dement Geriatr Cogn Disord 22:194-9. 2006..018). Changes in MMSE subscores paralleled the clinical diagnostic criteria for FTD. The more rapid progression on the language subscore was observed in both language and behavioral variants of FTD...
- Effects of aging on 5-HT(2A) R binding: a HRRT PET study with and without partial volume correctionsHiroyuki Uchida
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Int J Geriatr Psychiatry 26:1300-8. 2011....
- Development of supportive services for frontotemporal dementias through community engagementAdriana Shnall
Baycrest Health Sciences, Toronto, Ontario, Canada
Int Rev Psychiatry 25:246-52. 2013..The strength of these interventions is that services were developed with involvement of stakeholders in FTD care from the start, to deal with gaps in services in a sustainable way...