Research Topics
| Benoit BarbeauSummaryCountry: Canada Publications
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Detail Information
Publications
Polarized expression of the membrane ASP protein derived from HIV-1 antisense transcription in T cellsIsabelle Clerc
Universite Montpellier 1, Centre d Etudes d Agents Pathogenes et Biotechnologies pour la Sante, Montpellier, France
Retrovirology 8:74. 2011..The objective of this present study was to clearly demonstrate that ASP is effectively expressed in infected T cells and to provide a better characterization of its subcellular localization...
HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylatedMarie Hélène Cavanagh
Centre de Recherche en Infectiologie, Centre Hospitalier Universitaire de Quebec, Pavillon CHUL, Quebec, G1V 4G2, Canada
Retrovirology 3:15. 2006..Thorough characterization is required to demonstrate the existence of these transcripts and gain insight into their role in retrovirus biology...
Human T-cell lymphotropic virus type 3 (HTLV-3)- and HTLV-4-derived antisense transcripts encode proteins with similar Tax-inhibiting functions but distinct subcellular localizationEmilie Larocque
Departement des Sciences Biologiques, Universite du Quebec a Montreal, Room SB R860, 2080 Saint Urbain Montréal, Quebec, Canada H2X 3X8
J Virol 85:12673-85. 2011..These results further demonstrate that retroviral antisense transcription is not exclusive to HTLV-1 and HTLV-2 and that APH-3 and APH-4 could impact HTLV-3 and HTLV-4 replication...
Reduced expression of both syncytin 1 and syncytin 2 correlates with severity of preeclampsiaAmandine Vargas
Universite du Quebec a Montreal, Département des sciences biologiques and Centre de recherche BioMed, Montreal, Quebec, Canada
Reprod Sci 18:1085-91. 2011..These HERV proteins could thereby be used as potential markers for the early diagnosis of PE...
Upregulation of human T-cell leukemia virus type 1 antisense transcription by the viral tax proteinSebastien Landry
Universite du Quebec a Montreal, Departement des Sciences Biologiques, Centre de recherche BioMed, Montreal, Quebec, Canada
J Virol 83:2048-54. 2009..The cellular DNA context could thus affect the level of HBZ mRNA expression in infected cells...
Transcriptional and functional studies of Human Endogenous Retrovirus envelope EnvP(b) and EnvV genes in human trophoblastsAmandine Vargas
Universite du Quebec a Montreal, Département des sciences biologiques and Centre de recherche BioMed, 2080 St Urbain, Montreal, Quebec, Canada H2X 3X8
Virology 425:1-10. 2012..Our results demonstrate that both env genes are expressed in human trophoblasts but are not required for syncytialization...
Activation of LTRs from different human endogenous retrovirus (HERV) families by the HTLV-1 tax protein and T-cell activatorsChirine Toufaily
Departement des Sciences Biologiques, Universite du Quebec a Montreal, SB R860, 2080 St Urbain, Montreal, Quebec, H2X 3X8, Canada
Viruses 3:2146-59. 2011..Our results thus demonstrated that HTLV-1 Tax activates several HERV LTRs. This raises the possibility that upregulated HERV expression could be involved in diseases associated with HTLV-1 infection...
A new luciferase-based quantitative assay for the evaluation of human trophoblast fusionAmandine Vargas
Département des sciences biologiques and Centre de recherche BioMed, Universite du Quebec a Montreal, Montreal, Quebec, Canada
Reprod Sci 19:374-82. 2012..Similar results were obtained in primary trophoblasts. Our results highlight the effectiveness and accuracy of this new quantification assay for trophoblast fusion...
Endocrinology and cell signaling in human villous trophoblastCatherine Mounier
BioMed Research Center, Department of Biological Sciences, Universite du Quebec a Montreal, Montreal, Quebec, Canada
Methods Mol Biol 550:89-102. 2009..In this chapter we describe the current methods to study villous trophoblast differentiation and the cell-cell fusion of the cytotrophoblast cells...
Induction of galectin-1 expression by HTLV-I Tax and its impact on HTLV-I infectivitySonia Gauthier
Universite du Quebec a Montreal, Departement des Sciences Biologiques, 2080 St Urbain, Montreal, Quebec, H2X 3X8, Canada
Retrovirology 5:105. 2008..Several functions have been attributed to this protein including its capacity to increase cell-to-cell adhesion. Based on previous studies, we postulated that this protein could also accentuate HTLV-I infection...
Syncytin-2 plays an important role in the fusion of human trophoblast cellsAmandine Vargas
Departement des Sciences Biologiques, Universite du Quebec a Montreal, Montreal, Quebec, Canada
J Mol Biol 392:301-18. 2009..Overall, these results highlight the importance of Syncytin-2 in BeWo and primary human trophoblast cell fusion...
Does the HBZ gene represent a new potential target for the treatment of adult T-cell leukemia?Benoit Barbeau
Departement des Sciences Biologiques, Universite du Quebec a Montreal, Montreal, Canada
Int Rev Immunol 26:283-304. 2007..How could this new discovery be translated into possible new avenues for the prevention or treatment of ATL?..
Detection, characterization and regulation of antisense transcripts in HIV-1Sebastien Landry
Universite du Quebec a Montreal, Departement des Sciences Biologiques, Montreal Quebec, H2X 3X8, Canada
Retrovirology 4:71. 2007..The objective of the present study was to demonstrate the existence of antisense transcription in HIV-1 and to provide a better characterization of the transcript and its regulation...
Making sense out of antisense transcription in human T-cell lymphotropic viruses (HTLVs)Benoit Barbeau
Departement des Sciences Biologiques, Centre de recherche Bio Med, Universite du Quebec a Montreal, Montréal H2X3X8, Quebec, Canada
Viruses 3:456-68. 2011..Like HBZ, the APH proteins are localized in the nucleus of transfected cells and repress Tax-mediated viral transcription...
