Francis Rodriguez Bambico

Summary

Country: Canada

Publications

  1. doi The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus
    Francis R Bambico
    Neurobiological Psychiatry Unit, McGill University, McGill University Health Center, Montreal, Quebec, Canada Behavioral Neurobiology Laboratory, Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, Toronto, Ontario, Canada Electronic address
    Eur Neuropsychopharmacol 26:578-90. 2016
  2. doi Novel insights into depression and antidepressants: a synergy between synaptogenesis and neurogenesis?
    Francis Rodriguez Bambico
    Behavioural Neurobiology Laboratory, Research Neuroimaging Division, Center for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada
    Curr Top Behav Neurosci 15:243-91. 2013
  3. doi Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood
    Benoit Labonte
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada
    Int J Neuropsychopharmacol 15:1319-30. 2012
  4. doi Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle
    Sergio Dominguez-Lopez
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada
    J Psychopharmacol 26:830-44. 2012
  5. doi Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Canada H3A1A1
    Neurobiol Dis 37:641-55. 2010
  6. pmc Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus
    Francis Rodriguez Bambico
    Department of Psychiatry, McGill University, Montreal, QC, Canada
    Neuropsychopharmacology 35:2083-100. 2010
  7. doi Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects
    Ian Mahar
    McGill Group for Suicide Studies, Douglas Mental Health University Institute, Verdun, QC, Canada Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada Electronic address
    Neurosci Biobehav Rev 38:173-92. 2014
  8. doi Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex
    Benoit Labonte
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada
    Naunyn Schmiedebergs Arch Pharmacol 380:383-97. 2009
  9. ncbi Endocannabinoids in the treatment of mood disorders: evidence from animal models
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    Curr Pharm Des 15:1623-46. 2009
  10. doi Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada
    Eur Neuropsychopharmacol 19:215-28. 2009

Collaborators

Detail Information

Publications15

  1. doi The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus
    Francis R Bambico
    Neurobiological Psychiatry Unit, McGill University, McGill University Health Center, Montreal, Quebec, Canada Behavioral Neurobiology Laboratory, Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, Toronto, Ontario, Canada Electronic address
    Eur Neuropsychopharmacol 26:578-90. 2016
    ..These data indicate that URB597 acts, either directly or indirectly, on the 5-HT system, increases hippocampal BDNF expression, and modifies 5-HT1A and 5-HT2A/C function. ..
  2. doi Novel insights into depression and antidepressants: a synergy between synaptogenesis and neurogenesis?
    Francis Rodriguez Bambico
    Behavioural Neurobiology Laboratory, Research Neuroimaging Division, Center for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, ON, M5T 1R8, Canada
    Curr Top Behav Neurosci 15:243-91. 2013
    ....
  3. doi Adolescent amphetamine exposure elicits dose-specific effects on monoaminergic neurotransmission and behaviour in adulthood
    Benoit Labonte
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada
    Int J Neuropsychopharmacol 15:1319-30. 2012
    ..Thus, adolescent Amph exposure induces long-lasting neurophysiological alterations that may have implications for drug-seeking behaviour in the future...
  4. doi Short-term effects of melatonin and pinealectomy on serotonergic neuronal activity across the light-dark cycle
    Sergio Dominguez-Lopez
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada
    J Psychopharmacol 26:830-44. 2012
    ..This MLT-induced decrease in 5-HT neurotransmission may represent a biological mechanism underlying mood disorders characterized by increased MLT secretion, such as seasonal affective disorder...
  5. doi Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Canada H3A1A1
    Neurobiol Dis 37:641-55. 2010
    ..These suggest that long-term exposure to cannabinoids during adolescence induces anxiety-like and depression-like behaviours in adulthood and that this may be instigated by serotonergic hypoactivity and noradrenergic hyperactivity...
  6. pmc Genetic deletion of fatty acid amide hydrolase alters emotional behavior and serotonergic transmission in the dorsal raphe, prefrontal cortex, and hippocampus
    Francis Rodriguez Bambico
    Department of Psychiatry, McGill University, Montreal, QC, Canada
    Neuropsychopharmacology 35:2083-100. 2010
    ..Together, these results suggest that FAAH genetic deletion enhances anxiolytic-like and antidepressant-like effects, paralleled by altered 5-HT transmission and postsynaptic 5-HT(1A) and 5-HT(2A/2C) receptor function...
  7. doi Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects
    Ian Mahar
    McGill Group for Suicide Studies, Douglas Mental Health University Institute, Verdun, QC, Canada Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada Electronic address
    Neurosci Biobehav Rev 38:173-92. 2014
    ....
  8. doi Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex
    Benoit Labonte
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC H3A 1A1, Canada
    Naunyn Schmiedebergs Arch Pharmacol 380:383-97. 2009
    ..These data indicate that 5-HT excitatory transmission is selectively impaired at the mPFC level in this pharmacological model of schizophrenia...
  9. ncbi Endocannabinoids in the treatment of mood disorders: evidence from animal models
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    Curr Pharm Des 15:1623-46. 2009
    ....
  10. doi Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada
    Eur Neuropsychopharmacol 19:215-28. 2009
    ..These results suggest that CUS dramatically decreases 5-HT neural activity and 5-HT1A autoreceptor sensitivity, and may represent endophenotypic features of depressive-like states...
  11. doi Effect of delta-9-tetrahydrocannabinol on behavioral despair and on pre- and postsynaptic serotonergic transmission
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Dept Psychiatry, McGill University, Montreal, Quebec, Canada
    Prog Neuropsychopharmacol Biol Psychiatry 38:88-96. 2012
    ....
  12. ncbi The cannabinoid CB1 receptor and the endocannabinoid anandamide: possible antidepressant targets
    Francis Rodriguez Bambico
    McGill University, Neurobiological Psychiatry Unit, Department of Psychiatry, Research and Training Building, 1033 Pine Avenue West, Montreal Quebec, H3A 1A1, Canada
    Expert Opin Ther Targets 12:1347-66. 2008
    ....
  13. doi Chronic nandrolone decanoate exposure during adolescence affects emotional behavior and monoaminergic neurotransmission in adulthood
    Quentin Rainer
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University and McGill University Health Center, Montreal, QC, Canada
    Neuropharmacology 83:79-88. 2014
    ..These results provide evidence that nandrolone decanoate exposure during adolescence alters the emotional profile of animals in adulthood and significantly modifies both serotonergic and noradrenergic neurotransmission. ..
  14. doi Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand
    Rafael Ochoa-Sanchez
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University and McGill University Health Center, Montreal, Quebec, Canada
    J Neurosci 31:18439-52. 2011
    ..Since developing hypnotics that increase NREMS without altering sleep architecture remains a medical challenge, MT(2) receptors may represent a novel target for the treatment of sleep disorders...
  15. ncbi Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex
    Francis Rodriguez Bambico
    Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada H3A 1A1
    J Neurosci 27:11700-11. 2007
    ..These results demonstrate that CB1R agonists possess antidepressant-like properties and modulate 5-HT neuronal activity via the mPFCv...