Petronela Ancuta

Summary

Country: Canada

Publications

  1. doi Th17 lineage commitment and HIV-1 pathogenesis
    Petronela Ancuta
    Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Saint Luc Hospital, Pavillon Edouard Asselin, 264 Blvd René Lévesque East, Montreal, Quebec, Canada
    Curr Opin HIV AIDS 5:158-65. 2010
  2. pmc Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies peroxisome proliferator-activated receptor gamma as an intrinsic negative regulator of viral replication
    Annie Bernier
    Department of Microbiology, Infectiology, and Immunology, Universite de Montreal, Faculty of Medicine, Montreal Quebec, Canada
    Retrovirology 10:160. 2013
  3. pmc Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets
    Petronela Ancuta
    CRCHUM, Universite de Montreal, INSERM Unit 743, Montreal, Quebec, Canada
    BMC Genomics 10:403. 2009
  4. doi Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7
    Patricia Monteiro
    Department of Microbiology and Immunology, University of Montreal, Montreal, H3C 3J7 Quebec, Canada
    J Immunol 186:4618-30. 2011
  5. pmc Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection
    Annie Gosselin
    Department of Microbiology and Immunology, Universite de Montreal, Montreal, Quebec, Canada
    J Immunol 184:1604-16. 2010
  6. pmc The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid
    Vanessa Sue Wacleche
    Department of Microbiology and Immunology, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 7:e32964. 2012
  7. pmc Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection
    Elias A Said
    Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Hôpital St Luc, Montreal, Quebec, Canada
    Nat Med 16:452-9. 2010
  8. pmc Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation
    Mohamed El-Far
    Centre de recherche du Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada Department of Microbiology, Infectiology and Immunology, Universite de Montreal, Quebec, Canada
    J Gen Virol 96:1463-77. 2015
  9. pmc Down-regulation of CTLA-4 by HIV-1 Nef protein
    Mohamed El-Far
    Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Hôpital St Luc, Montreal, Quebec, Canada
    PLoS ONE 8:e54295. 2013
  10. doi Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection
    Julien van Grevenynghe
    Laboratoire d Immunologie, Centre de Recherche, Hopital Saint Luc, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Semin Immunol 20:196-203. 2008

Collaborators

Detail Information

Publications14

  1. doi Th17 lineage commitment and HIV-1 pathogenesis
    Petronela Ancuta
    Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Saint Luc Hospital, Pavillon Edouard Asselin, 264 Blvd René Lévesque East, Montreal, Quebec, Canada
    Curr Opin HIV AIDS 5:158-65. 2010
    ....
  2. pmc Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies peroxisome proliferator-activated receptor gamma as an intrinsic negative regulator of viral replication
    Annie Bernier
    Department of Microbiology, Infectiology, and Immunology, Universite de Montreal, Faculty of Medicine, Montreal Quebec, Canada
    Retrovirology 10:160. 2013
    ..We previously demonstrated that primary Th1Th17 cells are highly permissive to HIV-1, whereas Th1 cells are relatively resistant. Molecular mechanisms underlying these differences remain unknown...
  3. pmc Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets
    Petronela Ancuta
    CRCHUM, Universite de Montreal, INSERM Unit 743, Montreal, Quebec, Canada
    BMC Genomics 10:403. 2009
    ..CD16+ Mo produce pro-inflammatory cytokines and are expanded in certain inflammatory conditions including sepsis and HIV infection...
  4. doi Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7
    Patricia Monteiro
    Department of Microbiology and Immunology, University of Montreal, Montreal, H3C 3J7 Quebec, Canada
    J Immunol 186:4618-30. 2011
    ....
  5. pmc Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection
    Annie Gosselin
    Department of Microbiology and Immunology, Universite de Montreal, Montreal, Quebec, Canada
    J Immunol 184:1604-16. 2010
    ..It is necessary that new therapeutic strategies against HIV interfere with viral replication/persistence in discrete CCR6(+) T cell subsets...
  6. pmc The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid
    Vanessa Sue Wacleche
    Department of Microbiology and Immunology, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 7:e32964. 2012
    ....
  7. pmc Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection
    Elias A Said
    Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Hôpital St Luc, Montreal, Quebec, Canada
    Nat Med 16:452-9. 2010
    ..We describe a new function for PD-1 whereby microbial products inhibit T cell expansion and function by upregulating PD-1 levels and IL-10 production by monocytes after binding of PD-1 by PD-L1...
  8. pmc Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation
    Mohamed El-Far
    Centre de recherche du Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada Department of Microbiology, Infectiology and Immunology, Universite de Montreal, Quebec, Canada
    J Gen Virol 96:1463-77. 2015
    ..This also highlights the propensity of HIV-1 to evade restriction of the key negative immune regulator CTLA-4 on cell activation and viral replication, and therefore contributes to the overall HIV-1 pathogenesis. ..
  9. pmc Down-regulation of CTLA-4 by HIV-1 Nef protein
    Mohamed El-Far
    Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Hôpital St Luc, Montreal, Quebec, Canada
    PLoS ONE 8:e54295. 2013
    ..Down-regulation of CTLA-4 may contribute to the mechanisms by which HIV-1 sustains T cell activation, a critical step in viral replication and dissemination...
  10. doi Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection
    Julien van Grevenynghe
    Laboratoire d Immunologie, Centre de Recherche, Hopital Saint Luc, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Semin Immunol 20:196-203. 2008
    ....
  11. pmc Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers
    Mohammad Ali Jenabian
    Chronic Viral Illness Service, McGill University Health Centre, Montreal, Quebec, Canada Research Institute, McGill University Health Centre, Montreal, Quebec, Canada
    PLoS ONE 8:e78146. 2013
    ..These results suggest a distinctive Trp catabolism and Th17/Treg balance in HIV progressors and EC. Thus, IDO-induced immune-metabolism may be considered as a new inflammation-related marker for HIV-1 disease progression. ..
  12. pmc HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    Nicolas Chomont
    Laboratoire d Immunologie, Centre de Recherche du Centre Hospitalier de l Université de Montréal Saint Luc, Montreal, Quebec, Canada
    Nat Med 15:893-900. 2009
    ....
  13. pmc Sustained hyperresponsiveness of dendritic cells is associated with spontaneous resolution of acute hepatitis C
    Sandy Pelletier
    Centre de recherche du Centre Hospitalier de l Universite de Montreal, Hôpital St Luc, Montreal, Quebec, Canada
    J Virol 87:6769-81. 2013
    ..Altogether, our results suggest that the immature pDC phenotype and sustained pDC and mDC hyperresponsiveness are associated with spontaneous resolution of acute HCV infection...
  14. pmc Regulatory T cells in HIV infection: can immunotherapy regulate the regulator?
    Mohammad Ali Jenabian
    Chronic Viral Illnesses Service, McGill University Health Centre, 3650 St Urbain Street, Montreal, QC, Canada H2X 2P4
    Clin Dev Immunol 2012:908314. 2012
    ..However, such approaches require a better understanding of the time upon infection when interfering with Treg function may not cause a deleterious state of hyperimmune activation...