Research Topics
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Publications
The functional significance of K-complexesFlorin Amzica
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, G1K 7P4, Canada
Sleep Med Rev 6:139-49. 2002..The KC is mainly a spontaneous event generated in cortical networks. During nocturnal epileptic seizures, the KCs are precursors of paroxysmal spike-wave complexes...
Neuronal and glial membrane potentials during sleep and paroxysmal oscillations in the neocortexF Amzica
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
J Neurosci 20:6648-65. 2000....
Spatial buffering during slow and paroxysmal sleep oscillations in cortical networks of glial cells in vivoFlorin Amzica
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada, G1K 7P4
J Neurosci 22:1042-53. 2002....
Glial and neuronal interactions during slow wave and paroxysmal activities in the neocortexFlorin Amzica
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
Cereb Cortex 12:1101-13. 2002..Together with the variation of neuronal excitability, these results suggest that the glial uptake of K(+) contributes to the abridged duration of the paroxysmal depolarization...
In vivo electrophysiological evidences for cortical neuron-glia interactions during slow (<1 Hz) and paroxysmal sleep oscillationsFlorin Amzica
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
J Physiol Paris 96:209-19. 2002..Similar mechanisms as those described during the slow oscillation promote the periodic (2-3 Hz) recurrence of spike-wave complexes...
Physiology of sleep and wakefulness as it relates to the physiology of epilepsyFlorin Amzica
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada
J Clin Neurophysiol 19:488-503. 2002....
Extracellular calcium fluctuations and intracellular potentials in the cortex during the slow sleep oscillationM Massimini
Laboratoire de Neurophysiologie, , , Quebec G1K 7P4, Canada
J Neurophysiol 85:1346-50. 2001..Thus the periods of silence occurring in the cortical network during slow wave sleep are promoted by recurrent [Ca](out) depletions...
Coalescence of sleep rhythms and their chronology in corticothalamic networksM Steriade
Laboratoire de Neurophysiologie, Faculte de Medicine, Universite Laval, Quebec G1K 7P4, Canada
Sleep Res Online 1:1-10. 1998..This unexpectedly rich activity raises the possibility that, during sleep, the brain is occupied to specify/reorganize circuits and to consolidate memory traces acquired during wakefulness...
Sleep oscillations developing into seizures in corticothalamic systemsM Steriade
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
Epilepsia 44:9-20. 2003..5-2.5 Hz, often associated with fast runs at 10-15 Hz, as in the Lennox-Gastaut syndrome...
Slow sleep oscillation, rhythmic K-complexes, and their paroxysmal developmentsM Steriade
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada
J Sleep Res 7:30-5. 1998..We also show that the slow cortical oscillation underlies the onset of spike-wave seizures during sleep by transforming the periodic K-complexes into recurrent paroxysmal spike-wave complexes...
Hyperpolarisation rectification in cat lateral geniculate neurons modulated by intact corticothalamic projectionsD A Nita
Laboratoire de Neurophysiologie, , , Quebec, Canada G1K 7P4
J Physiol 552:325-32. 2003....
Activity-dependent layer-specific changes in the extracellular chloride concentration and chloride driving force in the rat hippocampusD Kroeger
Centre de Recherche Universite Laval Robert Giffard, University Laval, Quebec, Canada
J Neurophysiol 103:1905-14. 2010....
[Cellular basis of transition between sleep and electrographic seizures]Mircea Steriade
Laboratoire de Neurophysiologie, Département d anatomie et physiologie, Faculte de Medecine, Universite Laval, Quebec, G1K 7P4 Canada
Med Sci (Paris) 19:999-1002. 2003..Simultaneously, thalamocortical neurons are steadily inhibited and cannot relay signals from the outside world to cortex. This may explain the unconsciousness during certain types of epilepsy...
Nonneuronal origin of CO2-related DC EEG shifts: an in vivo study in the catDragos A Nita
Laboratoire de Neurophysiologie, , , Quebec G1K 7P4, Canada
J Neurophysiol 92:1011-22. 2004..We suggest that potentials generated by the BBB are the major source of epicortical/cranial DC shifts recorded under conditions affecting brain pH and/or cerebral blood flow...
Cholinergic action on cortical glial cells in vivoJosée Seigneur
Laboratoire de Neurophysiologie, Faculte de Medecine, Universite Laval, Quebec, Canada G1K 7P4
Cereb Cortex 16:655-68. 2006....
Participation of cortical glial cells to the genesis of spike-wave seizuresFlorin Amzica
Department of Anatomy and Physiology, Laval University, Quebec, Canada
Adv Neurol 97:173-82. 2006
Hypersensitivity of the anesthesia-induced comatose brainDaniel Kroeger
Laboratoire de Neurophysiologie, Centre de Recherche Universite Laval Robert Giffard, Quebec, Quebec, Canada G1J 2G3
J Neurosci 27:10597-607. 2007..These findings raise the issue of what burst spontaneity during anesthesia-induced coma means and opens new venues for the handling of comatose patients...
