Research Topics
| Xavier IntesSummaryAffiliation: Advanced Research Technologies Country: Canada Publications
Research Grants
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Detail Information
Publications
Detection limit enhancement of fluorescent heterogeneities in turbid media by dual-interfering excitationXavier Intes
Department of Biophysics and Biochemistry, University of Pennsylvania, Philadelphia 19104, USA
Appl Opt 41:3999-4007. 2002..To detect the same inhomogeneity, less concentration and lifetime contrast is required with dual-interfering sources...- Diffuse optical tomography with physiological and spatial a priori constraintsXavier Intes
Department of Biophysics and Biochemistry, University of Pennsylvania, Philadelphia, PA 19104, USA
Phys Med Biol 49:N155-63. 2004..More accurate recovery of the two main functional parameters that are the blood volume and the relative saturation is demonstrated through simulations by using our method compared to actual techniques... - Non-PET functional imaging techniques: opticalXavier Intes
Biomedical Optical Imaging, Advanced Research Technologies ART, 2300 Alfred Nobel Boulevard, Saint Laurent, Quebec H4S 2A4, Canada
Radiol Clin North Am 43:221-34, xii. 2005..This is followed by a survey of the three main applications: brain imaging, muscle imaging, and breast imaging. Lastly, the future outlook of the technology is presented, highlighting the new promises based on recent breakthroughs... - Time-domain optical mammography SoftScan: initial resultsXavier Intes
Art, Advanced Research Technologies, Saint Laurent Quebec, Canada
Acad Radiol 12:934-47. 2005..In this study, the authors report quantitative measurements of these components and the functional contrast between healthy and diseased tissue... - Correlation between near-infrared spectroscopy and magnetic resonance imaging of rat brain oxygenation modulationYu Chen
Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA
Phys Med Biol 48:417-27. 2003..A linear relationship with high correlation coefficient between the relative changes in the BOLD MRI signal and the NIRS signal is observed... - In vivo continuous-wave optical breast imaging enhanced with Indocyanine GreenXavier Intes
Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Med Phys 30:1039-47. 2003..These results provide further evidence that in vivo pharmacokinetics of ICG in breast tumors may be a useful diagnostic tool for differentiation of benign and malignant pathologies... - Development of high-sensitivity near-infrared fluorescence imaging device for early cancer detectionYu Chen
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
Biomed Instrum Technol 39:75-85. 2005..Also, this portable device would be complementary to x-ray mammography and provide add-on information on early diagnosis and localization of breast tumor... - Adaptive calibration for object localization in turbid media with interfering diffuse photon density wavesYu Chen
Department of Biophysics and Biochemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Appl Opt 41:7325-33. 2002..Experimental data on human breast phantoms demonstrate that localization accuracy within several millimeters has been accomplished through this method... - Probing rat brain oxygenation with near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI)Yu Chen
Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA
Adv Exp Med Biol 510:199-204. 2003 - Analysis on performance and optimization of frequency-domain near-infrared instrumentsTao Tu
University of Pennsylvania, Department of Electrical Engineering, Department of Biochemistry and Biophysics, Philadelphia, Pennsylvania 19104, USA
J Biomed Opt 7:643-9. 2002..This kind of method can be used to design suitable instruments for various applications. We also analyze the selection of the instrument parameters to achieve optimal performance at an efficient cost using this analytical model... - Projection access order in algebraic reconstruction technique for diffuse optical tomographyXavier Intes
Department of Biophysics and Biochemistry, University of Pennsylvania, Philadelphia 19104, USA
Phys Med Biol 47:N1-10. 2002..We show that by selecting proper projection access order, the convergence speed can be significantly improved when ART is used to perform DOT. Moreover, low-contrast detection is improved... - Reconstruction of spatially resolved pharmacokinetic rate images of fluorescence agents in FDOTBurak Alacam
Dept. of Electrical Computer and Systems Engineering, Rensselaer Polytechnic Institute, Troy, New York 19102, USA
Conf Proc IEEE Eng Med Biol Soc 1:5627-30. 2006.... 
Pharmacokinetic-rate images of indocyanine green for breast tumors using near-infrared optical methodsBurak Alacam
Department of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
Phys Med Biol 53:837-59. 2008..Our study indicates that the pharmacokinetic-rate images may provide superior information than single set of pharmacokinetic rates estimated from the entire breast tissue for breast cancer diagnosis...- Diffuse optical tomography with a priori anatomical informationMurat Guven
Electrical, Computer, and Systems Engineering Department, Rensselaer Polytechnic Institute, Troy, NY, USA
Phys Med Biol 50:2837-58. 2005..Extensive numerical simulations demonstrate that the proposed method avoids undesirable bias towards anatomical prior information and leads to significantly improved spatial resolution and quantitative accuracy... - Extended kalman filtering for the modeling and analysis of ICG pharmacokinetics in cancerous tumors using NIR optical methodsBurak Alacam
Department of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
IEEE Trans Biomed Eng 53:1861-71. 2006..Our study indicates that, in addition to the pharmacokinetic rates, the EKF model may provide parameters that may be useful for tumor differentiation...
Research Grants
- Fast Optical Imager for tumor detectionXavier Intes; Fiscal Year: 2005..abstract_text> ..