Murat Can

Summary

Publications

  1. doi request reprint Ischemia modified albumin and plasma oxidative stress markers in Alzheimer's disease
    Murat Can
    Department of Biochemistry, Bulent Ecevit University, Faculty of Medicine, Zonguldak, Turkey
    Eur Neurol 69:377-80. 2013
  2. doi request reprint Evaluation of serum lipid levels in children
    Murat Can
    Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University Formerly Karaelmas University, Zonguldak, Turkey
    Pediatr Cardiol 34:566-9. 2013
  3. ncbi request reprint Placental prostate-specific antigen content in preeclampsia
    Murat Can
    Department of Biochemistry, Faculty of Medicine, Karaelmas University, Zonguldak, Turkey
    Acta Biochim Pol 59:367-9. 2012
  4. doi request reprint Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury
    M Can
    Department of Biochemistry, Faculty of Medicine, Karaelmas University, Zonguldak, Turkey
    Acta Anaesthesiol Scand 53:1068-72. 2009
  5. doi request reprint Inflammatory markers in preeclamptic patients
    Murat Can
    Karaelmas University, Faculty of Medicine, Department of Biochemistry, Karaelmas University of Medicine, Zonguldak, Turkey
    Clin Chem Lab Med 49:1469-72. 2011
  6. ncbi request reprint The effect of montelukast on soluble interleukin-2 receptor and tumor necrosis factor alpha in pediatric asthma
    Murat Can
    Department of Biochemistry, Karaelmas University of Medicine, Zonguldak, Turkey
    Allergy Asthma Proc 27:383-6. 2006
  7. pmc Evaluation of effects of ischaemia on the albumin cobalt binding (ACB) assay in patients exposed to trauma
    M Can
    Department of Biochemistry, Karaelmas University of Medicine, Zonguldak, Turkey
    Emerg Med J 23:537-9. 2006
  8. doi request reprint Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia
    Murat Can
    Department of Biochemistry, Zonguldak Karaelmas University Medical School, Zonguldak, Turkey
    Kaohsiung J Med Sci 27:173-6. 2011
  9. ncbi request reprint Serum cardiovascular risk factors in obstructive sleep apnea
    Murat Can
    Karaelmas University, Faculty of Medicine, Department of Biochemistry, Zonguldak, Turkey
    Chest 129:233-7. 2006
  10. doi request reprint Dexmedetomidine did not reduce the effects of tourniquet-induced ischemia-reperfusion injury during general anesthesia
    Evrim Bostankolu
    Department of Anesthesiology and Reanimation, Zonguldak Karaelmas University, Zonguldak, Turkey
    Kaohsiung J Med Sci 29:75-81. 2013

Collaborators

Detail Information

Publications40

  1. doi request reprint Ischemia modified albumin and plasma oxidative stress markers in Alzheimer's disease
    Murat Can
    Department of Biochemistry, Bulent Ecevit University, Faculty of Medicine, Zonguldak, Turkey
    Eur Neurol 69:377-80. 2013
    ..Therefore, we evaluated the IMA and oxidant status by measuring serum uric acid, albumin and gamma-glutamyltransferase (GGT) in AD...
  2. doi request reprint Evaluation of serum lipid levels in children
    Murat Can
    Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University Formerly Karaelmas University, Zonguldak, Turkey
    Pediatr Cardiol 34:566-9. 2013
    ..No significant difference was found for the other serum lipid levels among any of the age groups. This study provided pediatric reference intervals for the lipid parameters for children...
  3. ncbi request reprint Placental prostate-specific antigen content in preeclampsia
    Murat Can
    Department of Biochemistry, Faculty of Medicine, Karaelmas University, Zonguldak, Turkey
    Acta Biochim Pol 59:367-9. 2012
    ..Further studies will be necessary to define the roles of PSA more precisely and to examine its effects on the pathophysiology of preeclampsia...
  4. doi request reprint Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury
    M Can
    Department of Biochemistry, Faculty of Medicine, Karaelmas University, Zonguldak, Turkey
    Acta Anaesthesiol Scand 53:1068-72. 2009
    ..The aim of this study was to compare the anti-inflammatory response of methylprednisolone and the alpha2-agonist dexmedetomidine in spinal cord injury (SCI)...
  5. doi request reprint Inflammatory markers in preeclamptic patients
    Murat Can
    Karaelmas University, Faculty of Medicine, Department of Biochemistry, Karaelmas University of Medicine, Zonguldak, Turkey
    Clin Chem Lab Med 49:1469-72. 2011
    ..In this study, we aimed to evaluate some inflammatory markers in pre-eclamptic and normotensive pregnants...
  6. ncbi request reprint The effect of montelukast on soluble interleukin-2 receptor and tumor necrosis factor alpha in pediatric asthma
    Murat Can
    Department of Biochemistry, Karaelmas University of Medicine, Zonguldak, Turkey
    Allergy Asthma Proc 27:383-6. 2006
    ..674; p < 0.01). This study indicates that montelukast improves clinical parameters and shows anti-inflammatory response by decreasing serum sIL-2R and TNF-alpha levels...
  7. pmc Evaluation of effects of ischaemia on the albumin cobalt binding (ACB) assay in patients exposed to trauma
    M Can
    Department of Biochemistry, Karaelmas University of Medicine, Zonguldak, Turkey
    Emerg Med J 23:537-9. 2006
    ..To date, however, the way in which alterations in metal binding sites of human serum albumin depend on ischaemic events has not been reported in detail...
  8. doi request reprint Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia
    Murat Can
    Department of Biochemistry, Zonguldak Karaelmas University Medical School, Zonguldak, Turkey
    Kaohsiung J Med Sci 27:173-6. 2011
    ..In conclusion, our initial data show that no clinical features could reliably differentiate macroprolactinemic from true hyperprolactinemic patients, but at least one of these symptoms was present in most macroprolactinemic patients...
  9. ncbi request reprint Serum cardiovascular risk factors in obstructive sleep apnea
    Murat Can
    Karaelmas University, Faculty of Medicine, Department of Biochemistry, Zonguldak, Turkey
    Chest 129:233-7. 2006
    ..Obstructive sleep apnea (OSA) patients have increased cardiovascular morbidity and mortality. The cardiovascular markers associated with OSA are currently not defined...
  10. doi request reprint Dexmedetomidine did not reduce the effects of tourniquet-induced ischemia-reperfusion injury during general anesthesia
    Evrim Bostankolu
    Department of Anesthesiology and Reanimation, Zonguldak Karaelmas University, Zonguldak, Turkey
    Kaohsiung J Med Sci 29:75-81. 2013
    ....
  11. pmc Mitigation of indomethacin-induced gastric mucosal lesions by a potent specific type V phosphodiesterase inhibitor
    Kemal Karakaya
    Department of General Surgery, Zonguldak Karaelmas University, Medical Faculty, 67600 Kozlu, Zonguldak, Turkey
    World J Gastroenterol 15:5091-6. 2009
    ..To investigate the gastroprotective effect of vardenafil against indomethacin-induced gastric damage...
  12. ncbi request reprint Prostate specific antigen levels after acute myocardial infarction
    Serefden Acikgoz
    Department of Biochemistry, Zonguldak Karaelmas University, Turkey
    Acta Biochim Pol 58:541-5. 2011
    ..The lower tPSA levels on day 2 suggest that tPSA can be eliminated rapidly from the circulation on days 1 and 2, probably through the formation of complexes of tPSA with acute phase proteins...
  13. ncbi request reprint The effect of treatment with montelukast on levels of serum interleukin-10, eosinophil cationic protein, blood eosinophil counts, and clinical parameters in children with asthma
    Birol Yüksel
    Department of Pediatrics, Karaelmas University Faculty of Medicine, Zonguldak, Turkey
    Turk J Pediatr 51:460-5. 2009
    ..Our study indicates that montelukast provides clinical benefits for children with chronic asthma and produces an anti-inflammatory response by increasing serum IL-10 levels,..
  14. ncbi request reprint Determinants of plasma homocysteine in coal miners
    A Gorkem Mungan
    Bulent Ecevit University, School of Medicine, Department of Medical Biochemistry, School of Medicine, Bulent Ecevit University, Zonguldak, Turkey
    Acta Biochim Pol 60:443-9. 2013
    ..In our study we aimed to evaluate the association between serum homocysteine (Hcy), vitamin B12, cystatin C and folate levels in the blood of underground coal miners...
  15. ncbi request reprint Effects of angiotensin-converting enzyme gene polymorphism and serum vitamin D levels on ambulatory blood pressure measurement and left ventricular mass in Turkish hypertensive population
    Eyup Kulah
    Department of Nephrology, Zonguldak Karaelmas University, Faculty of Medicine, Zonguldak, Turkey
    Blood Press Monit 12:207-13. 2007
    ..This study was designed to examine the effect of ACE gene polymorphisms on 24-h ambulatory blood pressure measurement (24 h) values, vitamin D levels and target organ damage in hypertensive patients...
  16. doi request reprint Effect of ghrelin on inflammatory response in lung contusion
    Berrak Guven
    Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University Formerly Karaelmas University, Zonguldak, Turkey
    Kaohsiung J Med Sci 29:69-74. 2013
    ..In conclusion, our study demonstrates that acute lung injury initiated proinflammatory responses and ghrelin administration showed an anti-inflammatory effect in lung contusion...
  17. pmc Levels of oxidized LDL, estrogens, and progesterone in placenta tissues and serum paraoxonase activity in preeclampsia
    Serefden Acikgoz
    Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University, 67630 Zonguldak, Turkey
    Mediators Inflamm 2013:862982. 2013
    ..The serum PON1 activity is probably important in the inhibition of OxLDL in preeclampsia...
  18. ncbi request reprint Comparison of angiotensin-converting enzyme, malonaldehyde, zinc, and copper levels in preeclampsia
    Serefden Acikgoz
    Department of Biochemistry, Faculty of Medicine, Karaelmas University, Zonguldak, Turkey
    Biol Trace Elem Res 113:1-8. 2006
    ..Furthermore, deficiency in placental zinc also plays a role in the biosynthesis of connective tissue, maintaining its integrity, which might have an impact on the structure of the spiral arteries...
  19. doi request reprint Effect of dexmedetomidine on testicular torsion/detorsion damage in rats
    Volkan Hanci
    Department of Anesthesiology and Reanimation, Karaelmas University Medical Faculty, Zonguldak, Turkey
    Urol Int 84:105-11. 2010
    ..We assessed the antioxidant activity of dexmedetomidine (DEX) during an ischemic period in a rat model of testicular torsion/detorsion (T/DT) by using biochemical and histopathological methods...
  20. ncbi request reprint Oxidized LDL accumulation in experimental renal ischemia reperfusion injury model
    Eyup Kulah
    Department of Nephrology, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
    Ren Fail 29:409-15. 2007
    ..Oxidized LDL (ox-LDL) was used as an oxidative stress biomarker, whereas paraoxonase (PON-1) activity was used as an antioxidative biomarker...
  21. ncbi request reprint Effects of dexmedetomidine pretreatment on bupivacaine cardiotoxicity in rats
    Volkan Hanci
    Departments of Anesthesiology and Reanimation, School of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
    Reg Anesth Pain Med 34:565-8. 2009
    ..We evaluated the effects of dexmedetomidine pretreatment on bupivacaine cardiotoxicity in anesthetized rats...
  22. pmc Effects of ozone oxidative preconditioning on radiation-induced organ damage in rats
    Fatma Ayca Gultekin
    Bulent Ecevit University, School of Medicine, Department of General Surgery, Kozlu, Zonguldak 67600, Turkey
    J Radiat Res 54:36-44. 2013
    ..In conclusion, data obtained from this study indicated that ozone could increase the endogenous antioxidant defense mechanism in rats and there by protect the animals from radiation-induced organ toxicity...
  23. ncbi request reprint High mobility group B1 levels in sepsis and Disseminated Intravascular Coagulation
    Zeynep M Eskici
    Department of Biochemistry, Zonguldak Karaelmas University, Faculty of Medicine, Esenköy Kozlu Zonguldak, Turkey
    Acta Biochim Pol 59:561-6. 2012
    ..HMGB1 levels were not significantly different in survivor and non survivor patients. HMGB1 levels did not differ in lower respiratory tract infection (LRTI) and urinary tract infection (UTI) in regard to the etiology of sepsis...
  24. ncbi request reprint Lipid peroxidation and homocysteine levels in Behçet's disease
    A Gorkem Mungan
    Department of Biochemistry, Karaelmas University, Faculty of Medicine, Zonguldak, Turkey
    Clin Chem Lab Med 44:1115-8. 2006
    ..The aim of this study was to investigate serum paraoxonase (PON1) activity in relation to homocysteine, malondialdehyde (MDA) and lipid parameters in active and inactive Behçet's disease (BD)...
  25. ncbi request reprint Effect of vardenafil on cerebral vasospasm following experimental subarachnoid hemorrhage in rats
    Sanser Gul
    Department of Neurosurgery, School of Medicine, Zonguldak Karaelmas University, Kozlu, Zonguldak 67600, Turkey
    J Clin Neurosci 17:1038-41. 2010
    ..008, G4 v. G2; p = 0.001, G4 v. G3; p = 0.005, G5 v. G2; p = 0.001, G5 v. G3). Our results confirm that vardenafil may induce vasodilatation and provide potential benefits in SAH therapy by preventing vasospasm...
  26. ncbi request reprint [The results of acetabular shelf procedures in Legg-Calve-Perthes disease]
    Hasan Hilmi Muratli
    Ankara Numune Egitim ve Arastirma Hastanesi, 5 Ortopedi ve Travmatoloji Kliniği
    Acta Orthop Traumatol Turc 37:138-43. 2003
    ..We evaluated the results of acetabular shelf procedures performed for the treatment of Legg-Calve-Perthes (LCP) disease...
  27. pmc Ischemia modified albumin increase indicating cardiac damage after experimental subarachnoid hemorrhage
    Serefden Acikgoz
    Department of Biochemistry, Faculty of Medicine, Bülent Ecevit University Formerly, Zonguldak Karaelmas University, 67630, Esenkoy, Kozlu, Zonguldak, Turkey
    BMC Neurosci 15:33. 2014
    ..IMA using by ACB test was detected with spectrophotometer...
  28. doi request reprint Reference values for serum levels of insulin-like growth factor 1 (IGF-1) and IGF-binding protein 3 (IGFBP-3) in the West Black Sea region of Turkey
    Berrak Guven
    Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey
    Scand J Clin Lab Invest 73:135-40. 2013
    ..The aim of this study was to determine the normal values of serum IGF-1 and IGFBP-3 in Turkish children and adults (1-79 years)...
  29. pmc Serum asymmetric dimethylarginine, nitrate, vitamin B(12), and homocysteine levels in individuals with pulmonary embolism
    Murat Altuntaş
    Department of Pulmonary Medicine, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak 67600, Turkey
    Mediators Inflamm 2011:215057. 2011
    ..The NO(3) levels increased and the ADMA and vitamin B(12) levels decreased with treatment in both groups. These results suggest that these parameters are not predictive of the development of CTEPH...
  30. ncbi request reprint Early cardiac abnormalities and serum N-terminal pro B-type natriuretic peptide levels in obese children
    Fatih Battal
    Department of Pediatrics, Karaelmas University, Zonguldak, Turkey
    J Pediatr Endocrinol Metab 24:723-6. 2011
    ..The aim of this study was to evaluate early cardiac abnormalities in obese children by the conventional echocardiography and to verify whether N-terminal pro B-type natriuretic peptide (NT-proBNP) differ between obese and healthy children...
  31. ncbi request reprint Early prediction of anthracycline induced cardiotoxicity
    Bedirhan Erkus
    Department of Biochemistry, Faculty of Medicine, Ankara University, Turkey
    Acta Paediatr 96:506-9. 2007
    ....
  32. ncbi request reprint Thymosin alpha 1 attenuates lipid peroxidation and improves fructose-induced steatohepatitis in rats
    Ferah Armutcu
    Department of Biochemistry and Clinical Biochemistry, Zonguldak Karaelmas University, Faculty of Medicine, Zonguldak, Turkey
    Clin Biochem 38:540-7. 2005
    ..Fructose leads to experimental steatosis in the liver by exerting its effect on some components of the oxidant/antioxidant system, and on several cytokines (interleukin-1beta, -2, and -6) in blood...
  33. pmc Antioxidant vitamins C, E and coenzyme Q10 vs dexamethasone: comparisons of their effects in pulmonary contusion model
    Mertol Gokce
    Department of Thoracic Surgery, Karaelmas University Medical Faculty, Zonguldak, Turkey
    J Cardiothorac Surg 7:92. 2012
    ..The goal of our study is to evaluate the effects of antioxidant vitamins (vitamin C and E), Coenzyme Q10 (CoQ10) and dexamethasone (Dxm) in experimental rat models with pulmonary contusion (PC)...
  34. ncbi request reprint The relationship of target organ damage and 24-hour ambulatory blood pressure monitoring with vitamin D receptor gene fok-I polymorphism in essential hypertension
    Eyup Kulah
    Department of Nephrology, Zonguldak Karaelmas University School of Medicine, Zonguldak, Turkey
    Kidney Blood Press Res 29:344-50. 2006
    ..The contribution of genetic factors in hypertension cannot be denied...
  35. ncbi request reprint Cystatin C can be affected by nonrenal factors: a preliminary study on leukemia
    Selda Demirtas
    University of Ufuk, Faculty of Medicine, Department of Biochemistry, Ankara, Turkey
    Clin Biochem 39:115-8. 2006
    ..The aim of this study was to evaluate the influence of malignancy and the impact of nephrotoxic drugs used in bone marrow transplantation (BMT) on the circulating levels of cystatin C in leukemia...
  36. doi request reprint Comparison of the calculated and measured osmolality in intracranial bleeding and head injury patients
    Serefden Acikgoz
    Department of Biochemistry, Faculty of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey
    J Emerg Med 36:217-9. 2009
    ..86(Na) + Glucose + Urea + Ethanol + 9] can be used to evaluate osmolality in ICH patients who were not treated with mannitol. In HI patients, none of the formulas should be used to calculate osmolality...
  37. ncbi request reprint Hepatorenal syndrome
    Selda Demirtas
    University of Ufuk, Faculty of Medicine, Department of Biochemistry, Ankara, Turkey
    Clin Chem Lab Med 44:379-86. 2006
    ..Laboratory and ultrasonographic tests based on non-invasive techniques are being investigated as possible diagnostic approaches...
  38. doi request reprint Serum prolidase activity in psoriasis patients
    Berrak Guven
    Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey
    Arch Dermatol Res 305:473-6. 2013
    ..However, further studies are needed to verify these findings as well as altered collagen synthesis in patients with psoriasis. ..
  39. doi request reprint Diagnostic value of serum ghrelin levels in prostate cancer
    N Aydin Mungan
    Department of Urology, Zonguldak Karaelmas University, School of Medicine, Zonguldak, Turkey
    Urol Int 80:245-8. 2008
    ..It was also shown that ghrelin has increased cell proliferation in vitro when added to PCA cell lines. The aim of this study was to evaluate the diagnostic value of serum ghrelin levels in detection of PCA...
  40. ncbi request reprint The evaluation of cystatin C, IL-1beta, and TNF-alpha levels in total saliva and gingival crevicular fluid from 11- to 16-year-old children
    A Evren Ulker
    Department of Pediatric Dentistry, Faculty of Dentistry, Gazi University, Ankara, Turkey
    J Periodontol 79:854-60. 2008
    ....