Nyasse B, Nono J, Sonke B, Denier C, Fontaine C. Trypanocidal activity of bergenin, the major constituent of Flueggea virosa, on Trypanosoma brucei. Pharmazie. 2004;59:492-4 pubmed
..Bergenin showed an inhibitory effect on the growth of the bloodstream form of Trypanosoma brucei with an IC50 value of 1 microM. ..
Nyasse B, Nkwengoua E, Sondengam B, Denier C, Willson M. Modified berberine and protoberberines from Enantia chlorantha as potential inhibitors of Trypanosoma brucei. Pharmazie. 2002;57:358-61 pubmed
..The inhibitory activities observed were in the range of 20 microM (ED50 values). ..
Nyasse B, Ngantchou I, Tchana E, Sonke B, Denier C, Fontaine C. Inhibition of both Trypanosoma brucei bloodstream form and related glycolytic enzymes by a new kolavic acid derivative isolated from Entada abyssinica. Pharmazie. 2004;59:873-5 pubmed
..The new derivative showed a strong and selective inhibitory activity on the GAPDH enzyme of Trypanosoma brucei with an IC50 value of 0.012 mM. ..
Nyasse B, Ngantchou I, Nono J, Schneider B. Antifilarial activity in vitro of polycarpol and 3-O-acetyl aleuritolic acid from cameroonian medicinal plants against Onchocerca gutturosa. Nat Prod Res. 2006;20:391-7 pubmed
..gutturosa using Amocarzine as positive control compound. The motility reduction values were 28.6 and 57.1%, and the inhibition of MTT reduction values 80.0 and 64.8% respectively. ..