Richard Njouom

Summary

Affiliation: Centre Pasteur du Cameroun
Country: Cameroon

Publications

  1. doi request reprint Viral etiology of influenza-like illnesses in Cameroon, January-December 2009
    Richard Njouom
    Service de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Infect Dis 206:S29-35. 2012
  2. pmc Hepatitis C virus prevalence and genetic diversity among pregnant women in Gabon, central Africa
    Guy Roger Ndong-Atome
    Laboratoire de Virologie, Centre International de Recherches Médicales CIRMF, BP 769, Franceville, Gabon
    BMC Infect Dis 8:82. 2008
  3. doi request reprint Predominance of hepatitis C virus genotype 4 infection and rapid transmission between 1935 and 1965 in the Central African Republic
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Gen Virol 90:2452-6. 2009
  4. doi request reprint Efficacy and safety of peginterferon alpha-2a/ribavirin in treatment-naive Cameroonian patients with chronic hepatitis C
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Med Virol 80:2079-85. 2008
  5. pmc Circulation of human influenza viruses and emergence of Oseltamivir-resistant A(H1N1) viruses in Cameroon, Central Africa
    Richard Njouom
    Laboratory of Virology, Centre Pasteur of Cameroon, Yaounde, Cameroon
    BMC Infect Dis 10:56. 2010
  6. doi request reprint Highly pathogenic avian influenza virus subtype H5N1 in ducks in the Northern part of Cameroon
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    Vet Microbiol 130:380-4. 2008
  7. doi request reprint Detection and characterization of hepatitis B virus strains from wild-caught gorillas and chimpanzees in Cameroon, Central Africa
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    Infect Genet Evol 10:790-6. 2010
  8. ncbi request reprint Evaluation of core and NS4B synthetic peptide-based immunoassays for the detection of hepatitis C virus antibodies in clinical samples from Cameroon, Central Africa
    Richard Njouom
    Service de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroon
    J Clin Virol 49:61-4. 2010
  9. ncbi request reprint The hepatitis C virus epidemic in Cameroon: genetic evidence for rapid transmission between 1920 and 1960
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroon
    Infect Genet Evol 7:361-7. 2007
  10. ncbi request reprint A cost-effective algorithm for the diagnosis of Hepatitis C virus infection and prediction of HCV viremia in Cameroon
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Virol Methods 133:223-6. 2006

Collaborators

Detail Information

Publications31

  1. doi request reprint Viral etiology of influenza-like illnesses in Cameroon, January-December 2009
    Richard Njouom
    Service de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Infect Dis 206:S29-35. 2012
    ..No information is available on the viral etiology of upper respiratory tract infections in Cameroon...
  2. pmc Hepatitis C virus prevalence and genetic diversity among pregnant women in Gabon, central Africa
    Guy Roger Ndong-Atome
    Laboratoire de Virologie, Centre International de Recherches Médicales CIRMF, BP 769, Franceville, Gabon
    BMC Infect Dis 8:82. 2008
    ..The prevalence and genetic diversity of HCV in pregnant women in Gabon, central Africa, is not known. We therefore evaluated the prevalence and the circulating genotypes of HCV in a large population cohort of pregnant women...
  3. doi request reprint Predominance of hepatitis C virus genotype 4 infection and rapid transmission between 1935 and 1965 in the Central African Republic
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Gen Virol 90:2452-6. 2009
    ..The hypothesis of a massive iatrogenic transmission during interventions for the control of endemic tropical diseases is discussed...
  4. doi request reprint Efficacy and safety of peginterferon alpha-2a/ribavirin in treatment-naive Cameroonian patients with chronic hepatitis C
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Med Virol 80:2079-85. 2008
    ..Virus subtype may influence the treatment outcome, since there is a great genetic diversity within Cameroonian HCV-1 and -4 genotypes...
  5. pmc Circulation of human influenza viruses and emergence of Oseltamivir-resistant A(H1N1) viruses in Cameroon, Central Africa
    Richard Njouom
    Laboratory of Virology, Centre Pasteur of Cameroon, Yaounde, Cameroon
    BMC Infect Dis 10:56. 2010
    ..The objective of this study was to assess the prevalence of influenza viruses circulating in Yaounde, Cameroon and determine their antigenic and genetic characteristics...
  6. doi request reprint Highly pathogenic avian influenza virus subtype H5N1 in ducks in the Northern part of Cameroon
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    Vet Microbiol 130:380-4. 2008
    ..Analysis of NA sequences of the virus demonstrated that it is closely related to the H5N1 isolates from Northern Nigeria, Sudan and Ivory Coast, suggesting a common virus ancestor...
  7. doi request reprint Detection and characterization of hepatitis B virus strains from wild-caught gorillas and chimpanzees in Cameroon, Central Africa
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    Infect Genet Evol 10:790-6. 2010
    ..We demonstrated the existence of gorillas' specific HBV strains distinct but related to those found in chimpanzees living in the same habitat in Cameroon, providing substantial evidence of species association of HBV in NHPs...
  8. ncbi request reprint Evaluation of core and NS4B synthetic peptide-based immunoassays for the detection of hepatitis C virus antibodies in clinical samples from Cameroon, Central Africa
    Richard Njouom
    Service de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroon
    J Clin Virol 49:61-4. 2010
    ..OBJECTIVE OF THIS STUDY: To evaluate the performance of HCV core and NS4B peptide-based immunoassays in the serodiagnosis of HCV infection in Cameroon subjects...
  9. ncbi request reprint The hepatitis C virus epidemic in Cameroon: genetic evidence for rapid transmission between 1920 and 1960
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroon
    Infect Genet Evol 7:361-7. 2007
    ....
  10. ncbi request reprint A cost-effective algorithm for the diagnosis of Hepatitis C virus infection and prediction of HCV viremia in Cameroon
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Virol Methods 133:223-6. 2006
    ..These results suggest an algorithm using ImmunoComb II HCV as a first test to screen anti-HCV positive subjects, and Hexagon HCV as a second test to discriminate between viremic and non-viremic HCV seropositive subjects...
  11. doi request reprint Transmission of hepatitis C virus among spouses in Cameroon and the Central African Republic
    Richard Njouom
    Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Med Virol 83:2113-8. 2011
    ..Inter-spouse transmission may have contributed to the high prevalence among elderly populations of Central Africa since some patients infected during healthcare subsequently transmitted the virus to their spouse...
  12. doi request reprint Crosses prior to parthenogenesis explain the current genetic diversity of tropical plant-parasitic Meloidogyne species (Nematoda: Tylenchida)
    Mireille Fargette
    IRD, UMR 1062 CBGP, Campus International de Baillarguet, CS30016, 34988 Montferrier sur Lez, France
    Infect Genet Evol 10:807-14. 2010
    ..Risk management strategies and tools must thus consider this complexity when designing quarantine implementation, resistance breeding programmes or molecular diagnostic...
  13. ncbi request reprint Distribution and heterogeneity of hepatitis C genotypes in hepatitis patients in Cameroon
    Christophe Pasquier
    Laboratoire de Virologie, Variabilité Virale, Hopital Purpan, TSA, Toulouse, France
    J Med Virol 77:390-8. 2005
    ..HCV Genotypes 1 and 4 are very heterogeneous in Cameroon, perhaps due to ancient infections. The homogeneity of HCV Genotype 2 indicates its more recent introduction from western Africa...
  14. ncbi request reprint High rate of hepatitis C virus infection and predominance of genotype 4 among elderly inhabitants of a remote village of the rain forest of South Cameroon
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroun, France
    J Med Virol 71:219-25. 2003
    ..The results suggest a cohort effect with an old, possibly iatrogenic, group exposure rather than a continuous exposure. A more in-depth population-based epidemiological study is needed to address this issue further...
  15. ncbi request reprint Low risk of mother-to-child transmission of hepatitis C virus in Yaounde, Cameroon: the ANRS 1262 study
    Richard Njouom
    Centre Pasteur du Cameroun, Yaounde, Cameroun Laboratoire de Virologie, CHU Toulouse Purpan, Toulouse, France
    Am J Trop Med Hyg 73:460-6. 2005
    ..None of those screened at 6 weeks and 6 months of age were HCV-RNA positive. The failure to detect HCV vertical transmission suggests that the mother-to-child transmission (MTCT) is not a major route of HCV transmission in Cameroon...
  16. ncbi request reprint Hepatitis C virus infection among pregnant women in Yaounde, Cameroon: prevalence, viremia, and genotypes
    Richard Njouom
    Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Med Virol 69:384-90. 2003
    ..The percentage of HCV seropositive pregnant women who had circulating HCV RNA was similar to that observed in Europe. Several HCV genotypes were found in Cameroon...
  17. pmc Hepatitis B and C virus infections in the three Pygmy groups in Cameroon
    Yacouba Foupouapouognigni
    Service de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroon
    J Clin Microbiol 49:737-40. 2011
    ..6%). Phylogenetic analyses showed cocirculation of two HBV genotypes, HBV-A3 and -E. Taken together, our results suggest different epidemiological scenarios concerning HBV and HCV infections in this population...
  18. ncbi request reprint Variable epidemic histories of hepatitis C virus genotype 2 infection in West Africa and Cameroon
    Regis Pouillot
    Centre Pasteur du Cameroun, Yaounde, Cameroon
    Infect Genet Evol 8:676-81. 2008
    ..This comparative genetic analysis indicates that Cameroon HCV-2 strains are derived from West African strains and that HCV-2 has undergone radically different epidemiological histories in the two regions...
  19. ncbi request reprint Hepatitis C virus infection in cameroon: A cohort-effect
    Eric Nerrienet
    Centre Pasteur du Cameroun, Yaounde, Cameroun
    J Med Virol 76:208-14. 2005
    ..This clearly indicates a cohort effect for which the seroprevalence trends are clearly related with the year of birth, rather than the age. The highest prevalence was observed among people born around 1940...
  20. ncbi request reprint Full-length genome sequences of hepatitis C virus subtype 4f
    Fatma Hmaied
    Service de Virologie, CHU de Toulouse, Institut Fédératif de Biologie, F 31059 Toulouse, France
    J Gen Virol 88:2985-90. 2007
    ..It is important to know the full-length sequences of HCV-4 subtypes in order to classify them correctly and to obtain more detailed knowledge about HCV epidemiology and sensitivity to interferon...
  21. pmc High prevalence and predominance of hepatitis delta virus genotype 1 infection in Cameroon
    Yacouba Foupouapouognigni
    Service de Virologie, Centre Pasteur du Cameroun, P O Box 1274, Yaounde, Cameroon
    J Clin Microbiol 49:1162-4. 2011
    ..Phylogenetic analyses showed the presence of HDV-1, HDV-5, HDV-6, and HDV-7 genotypes. These results enrich the limited data on HDV prevalence and molecular diversity in Cameroon...
  22. ncbi request reprint Assessment of HIV-1 subtyping for Cameroon strains using phylogenetic analysis of pol gene sequences
    Richard Njouom
    Laboratoire de Virologie, CHU Toulouse Purpan, Place Dr Baylac, TAS40031 31059 Cedex, Toulouse, France
    J Virol Methods 110:1-8. 2003
    ..However, it can be a useful method for HIV-1 subtyping, provided that the gene is amplifiable...
  23. pmc Characterization of Enteroviruses from Non-Human Primates in Cameroon Revealed Virus Types Widespread in Humans along with Candidate New Types and Species
    Serge Alain Sadeuh-Mba
    Service de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    PLoS Negl Trop Dis 8:e3052. 2014
    ..Overall, this study indicates that the genetic diversity of EVs among NHP is more important than previously known and could be the source of future new emerging human viral diseases. ..
  24. pmc Molecular characterization of measles viruses that circulated in Cameroon between 2010 and 2011
    Maurice Demanou
    WHO National Reference Laboratory for Measles, Centre Pasteur of Cameroon, Yaounde, Cameroon
    Virol J 10:71. 2013
    ..Genotype B3 is clearly the endemic genotype in most of African continent where it is widely distributed. We provide an update on the molecular characterization of wild-type MeVs that circulated in Cameroon between 2010 and 2011...
  25. pmc A low proportion of HBeAg among HBsAg-positive pregnant women with known HIV status could suggest low perinatal transmission of HBV in Cameroon
    Anfumbom KW Kfutwah
    Virology Service, Centre Pasteur du Cameroun, Membre du Réseau International des Instituts Pasteur, BP 1274 Yaounde, Cameroon
    Virol J 9:62. 2012
    ..In this study, we determined the prevalence of hepatitis B surface antigen (HBsAg) and HBeAg among pregnant women with known HIV status...
  26. ncbi request reprint Hepatitis B virus exposure during childhood in Cameroon, Central African Republic and Senegal after the integration of HBV vaccine in the expanded program on immunization
    Marie Anne Rey-Cuillé
    From the Unité de Recherche et d Expertise en Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France Institut des Sciences Biologiques, CNRS, Paris, France Service de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroun Laboratoire des Virus Oncogènes, Institut Pasteur de Bangui, Bangui, République Centrafricaine Laboratoire de Biologie Médicale, Institut Pasteur, Dakar, Sénégal Complexe Pédiatrique, Bangui, République Centrafricaine and Département de virologie, Hopital Saint Louis, Paris, France
    Pediatr Infect Dis J 32:1110-5. 2013
    ..We evaluated the prevalence of HBV exposure and infection after the integration of the HBV vaccine in the EPI...
  27. pmc High frequency and diversity of species C enteroviruses in Cameroon and neighboring countries
    Serge Alain Sadeuh-Mba
    Service de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
    J Clin Microbiol 51:759-70. 2013
    ..The extensive circulation of diverse HEV-C types and lineages in countries where OPV is massively used constitutes a major viral factor that could promote the emergence of recombinant cVDPVs in the Central African subregion...
  28. pmc Evaluating the performance of a rapid antigen test for the detection of influenza virus in clinical specimens from children in Cameroon
    Sebastien Kenmoe
    National Influenza Centre, Centre Pasteur of Cameroon, Yaounde, Cameroon Université de Yaoundé I, Yaounde, Cameroon
    Influenza Other Respir Viruses 8:131-4. 2014
    ..The excellent specificity of the RAT allowed for the rapid identification of influenza cases. However, negative results should be verified by rRT-PCR test because of limitations observed in sensitivity. ..
  29. ncbi request reprint Field evaluation of the Abbott ARCHITECT HIV Ag/Ab Combo immunoassay
    Anfumbom Kfutwah
    Service de Virologie, Centre Pasteur du Cameroun, Membre du Réseau International des Instituts Pasteur, Yaounde, Cameroun BP 1274, Yaounde, Cameroon Electronic address
    J Clin Virol 58:e70-5. 2013
    ..In spite of this, HIV diagnosis remains a challenge in sub-Saharan Africa, due to false positive reactivity. There is a continuous need for field evaluations and routine validations of fourth generation HIV tests in African populations...
  30. pmc An antiretroviral drug-naïve human immunodeficiency virus-1 infected woman with a persistent non-reactive proviral deoxyribonucleic acid polymerase chain reaction: a case report
    Anfumbom KW Kfutwah
    Service de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroun
    J Med Case Rep 7:152. 2013
    ..This observation, to the best of our knowledge, is the first time that it has been described in Africa...
  31. pmc Simian foamy virus transmission from apes to humans, rural Cameroon
    Sara Calattini
    Institut Pasteur, Paris, France
    Emerg Infect Dis 13:1314-20. 2007
    ..6%) of those who had had contact with monkeys. These data demonstrate efficient transmission of SFVs to humans in natural settings in central Africa, specifically following ape bites, and viral persistence in the human host...