Research Topics
| Eric NerrienetSummaryAffiliation: Phnom Penh Country: Cambodia Publications
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Detail Information
Publications
High efficacy of lopinavir/r-based second-line antiretroviral treatment after 24 months of follow up at ESTHER/Calmette Hospital in Phnom Penh, CambodiaLaurent Ferradini
Family Health International, Phnom Penh, Cambodia
J Int AIDS Soc 14:14. 2011..We describe the outcomes after 24 months for patients on LPV/r-based second-line regimens followed up by the ESTHER programme in Phnom Penh, Cambodia...
Characterization of a new simian immunodeficiency virus strain in a naturally infected Pan troglodytes troglodytes chimpanzee with AIDS related symptomsLucie Etienne
UMR145, Institut de Recherche pour le Développement IRD and Université Montpellier 1, Montpellier, France
Retrovirology 8:4. 2011..Here, we report a case of naturally-acquired SIVcpz infection in a P.t.troglodytes chimpanzee with clinical and biological data and analysis of viral evolution over the course of infection...
Hepatitis C virus infection in cameroon: A cohort-effectEric Nerrienet
Centre Pasteur du Cameroun, Yaounde, Cameroun
J Med Virol 76:208-14. 2005..This clearly indicates a cohort effect for which the seroprevalence trends are clearly related with the year of birth, rather than the age. The highest prevalence was observed among people born around 1940...
High rate of hepatitis C virus infection and predominance of genotype 4 among elderly inhabitants of a remote village of the rain forest of South CameroonRichard Njouom
Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaound, Cameroun, France
J Med Virol 71:219-25. 2003..The results suggest a cohort effect with an old, possibly iatrogenic, group exposure rather than a continuous exposure. A more in-depth population-based epidemiological study is needed to address this issue further...
Low prevalence of drug resistance transmitted virus in HIV Type 1-infected ARV-naive patients in CambodiaJanin Nouhin
HIV Hepatitis Laboratory, Pasteur Institute of Cambodia, Phnom Penh, Cambodia
AIDS Res Hum Retroviruses 25:543-5. 2009..04-8.04%) prevalence of transmitted drug-resistant strains in drug-naive patients was low in our study. Surveys of drug-resistant transmitted viruses should be regularly performed regarding the increasing access to HAART in Cambodia...
A cost-effective algorithm for the diagnosis of Hepatitis C virus infection and prediction of HCV viremia in CameroonRichard Njouom
Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
J Virol Methods 133:223-6. 2006..These results suggest an algorithm using ImmunoComb II HCV as a first test to screen anti-HCV positive subjects, and Hexagon HCV as a second test to discriminate between viremic and non-viremic HCV seropositive subjects...
High survival and treatment success sustained after two and three years of first-line ART for children in CambodiaPetros Isaakidis
Medecins Sans Frontieres, Phnom Penh, Cambodia
J Int AIDS Soc 13:11. 2010..The objective of this study was to assess two-and three-year survival, CD4 evolution and virological response among children on ART in a programmatic setting in Cambodia...
Plasmodium falciparum infection significantly impairs placental cytokine profile in HIV infected Cameroonian womenAnfumbom Kfutwah
Virology Laboratory, Centre Pasteur du Cameroun, Yaounde, Cameroon
PLoS ONE 4:e8114. 2009..falciparum and HIV in the stimulation of placental cytokines. This study assessed the impact of P. falciparum on placental cytokine profiles between HIV-1 positive and negative women...
Natural polymorphisms of HIV-1 CRF01_AE integrase coding region in ARV-naïve individuals in Cambodia, Thailand and Vietnam: an ANRS AC12 working group studyJanin Nouhin
Institut Pasteur du Cambodge, Laboratoire VIH Hepatites, Phnom Penh, Cambodia
Infect Genet Evol 11:38-43. 2011..If this substitution is confirmed to compromise the virologic response to raltegravir, further studies will be needed to better assess the prevalence of this substitution among CRF01_AE virus...
Efficacy and safety of peginterferon alpha-2a/ribavirin in treatment-naive Cameroonian patients with chronic hepatitis CRichard Njouom
Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
J Med Virol 80:2079-85. 2008..Virus subtype may influence the treatment outcome, since there is a great genetic diversity within Cameroonian HCV-1 and -4 genotypes...
Hepatitis C virus infection among pregnant women in Yaounde, Cameroon: prevalence, viremia, and genotypesRichard Njouom
Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
J Med Virol 69:384-90. 2003..The percentage of HCV seropositive pregnant women who had circulating HCV RNA was similar to that observed in Europe. Several HCV genotypes were found in Cameroon...
Mother-to-child transmission of human immunodeficiency virus type 1 in relation to the season in Yaounde, CameroonAhidjo Ayouba
Centre Pasteur du Cameroun, Yaounde, Cameroon
Am J Trop Med Hyg 69:447-9. 2003....
Effectiveness of highly active antiretroviral therapy in HIV-positive children: evaluation at 12 months in a routine program in CambodiaBart Janssens
Medecins Sans Frontieres, Phnom Penh, Cambodia
Pediatrics 120:e1134-40. 2007..We aimed to describe the clinical, immunologic, and virologic outcomes of pediatric patients with >12 months of highly active antiretroviral therapy in 2 routine programs in Cambodia...
Detection and characterization of hepatitis B virus strains from wild-caught gorillas and chimpanzees in Cameroon, Central AfricaRichard Njouom
Laboratoire de Virologie, Centre Pasteur du Cameroun, Yaounde, Cameroon
Infect Genet Evol 10:790-6. 2010..We demonstrated the existence of gorillas' specific HBV strains distinct but related to those found in chimpanzees living in the same habitat in Cameroon, providing substantial evidence of species association of HBV in NHPs...
Low risk of mother-to-child transmission of hepatitis C virus in Yaounde, Cameroon: the ANRS 1262 studyRichard Njouom
Centre Pasteur du Cameroun, Yaound, Cameroun; Laboratoire de Virologie, CHU Toulouse Purpan, Toulouse, France
Am J Trop Med Hyg 73:460-6. 2005..None of those screened at 6 weeks and 6 months of age were HCV-RNA positive. The failure to detect HCV vertical transmission suggests that the mother-to-child transmission (MTCT) is not a major route of HCV transmission in Cameroon...
Distribution and heterogeneity of hepatitis C genotypes in hepatitis patients in CameroonChristophe Pasquier
Laboratoire de Virologie, Variabilité Virale, Hopital Purpan, TSA, Toulouse, France
J Med Virol 77:390-8. 2005..HCV Genotypes 1 and 4 are very heterogeneous in Cameroon, perhaps due to ancient infections. The homogeneity of HCV Genotype 2 indicates its more recent introduction from western Africa...
Low rate of mother-to-child transmission of HIV-1 after nevirapine intervention in a pilot public health program in Yaoundé, CameroonAhidjo Ayouba
Centre Pasteur du Cameroun, BP 1274, Fondation Chantal Biya, Yaound, Cameroon
J Acquir Immune Defic Syndr 34:274-80. 2003..CONCLUSIONS: Our results indicate that the HIV-1 MTCT rate 6-8 weeks after NVP administration was not >13% (16/123), thus demonstrating the effectiveness of NVP for lowering the risk of HIV-1 MTCT in real-life settings...
Simian T cell leukaemia virus type I subtype B in a wild-caught gorilla (Gorilla gorilla gorilla) and chimpanzee (Pan troglodytes vellerosus) from CameroonEric Nerrienet
Laboratoire de Virologie, Centre Pasteur du Cameroun, , Cameroon
J Gen Virol 85:25-9. 2004..Such findings reinforce the hypothesis of interspecies transmission of STLV-I to humans, leading to the present day distribution of HTLV-I in central African inhabitants...
Effectiveness and safety of a generic fixed-dose combination of nevirapine, stavudine, and lamivudine in HIV-1-infected adults in Cameroon: open-label multicentre trialChristian Laurent
Institut de Recherche pour le Développement and Department of International Health, University of Montpellier UMR 145, Montpellier, France
Lancet 364:29-34. 2004..We aimed to assess these issues for one of the most frequently prescribed treatments in Africa, a generic fixed-dose combination of nevirapine, stavudine, and lamivudine...
Natural simian foamy virus infection in wild-caught gorillas, mandrills and drills from Cameroon and GabonSara Calattini
Unité d Epidémiologie et Physiopathologie des Virus Oncogènes, Département EMMI, Institut Pasteur, Paris, France
J Gen Virol 85:3313-7. 2004....
The hepatitis C virus epidemic in Cameroon: genetic evidence for rapid transmission between 1920 and 1960Richard Njouom
Laboratoire de Virologie, Centre Pasteur du Cameroun, BP 1274 Yaounde, Cameroon
Infect Genet Evol 7:361-7. 2007....
HIV-1 pol gene polymorphism and antiretroviral resistance mutations in drug-naive pregnant women in Yaoundé, CameroonAurelia Vessiere
J Acquir Immune Defic Syndr 42:256-8. 2006
Detection and molecular characterization of foamy viruses in Central African chimpanzees of the Pan troglodytes troglodytes and Pan troglodytes vellerosus subspeciesSara Calattini
, , Institut Pasteur, Paris, France
J Med Primatol 35:59-66. 2006..This raises, in such regions, the potential risk of a human retroviral infection of zoonotic origin linked to chimpanzees contacts, as already exemplified for STLV-1 and SIV infections...
