Jose A L Calbet

Summary

Publications

  1. doi request reprint The response of human skeletal muscle tissue to hypoxia
    Carsten Lundby
    The Copenhagen Muscle Research Centre, Rigshospitalet Sect 7652, 2100, Copenhagen, Denmark
    Cell Mol Life Sci 66:3615-23. 2009
  2. doi request reprint Effects of strength training on muscle fatigue mapping from surface EMG and blood metabolites
    Mikel Izquierdo
    Studies, Research and Sport Medicine Center, Government of Navarra, Pamplona, Navarra, Spain
    Med Sci Sports Exerc 43:303-11. 2011
  3. pmc Iliopsoas and gluteal muscles are asymmetric in tennis players but not in soccer players
    Joaquin Sanchis-Moysi
    Physical Education Department, Las Palmas de Gran Canaria University, Las Palmas de Gran Canaria, Spain
    PLoS ONE 6:e22858. 2011
  4. doi request reprint Skeletal muscle signaling response to sprint exercise in men and women
    Teresa Fuentes
    Department of Physical Education, Campus Universitario de Tafira, University of Las Palmas de Gran Canaria, 35017 Las Palmas de Gran Canaria, Spain
    Eur J Appl Physiol 112:1917-27. 2012
  5. pmc Adiposity and age explain most of the association between physical activity and fitness in physically active men
    Jose A Serrano-Sanchez
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
    PLoS ONE 5:e13435. 2010
  6. pmc Bone mass and the CAG and GGN androgen receptor polymorphisms in young men
    Amelia Guadalupe-Grau
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Islands, Spain
    PLoS ONE 5:e11529. 2010
  7. pmc Skeletal muscle vasodilatation during maximal exercise in health and disease
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, Las Palmas de Gran Canaria, 35017, Spain
    J Physiol 590:6285-96. 2012
  8. ncbi request reprint Is pulmonary gas exchange during exercise in hypoxia impaired with the increase of cardiac output?
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, 35017, Spain
    Appl Physiol Nutr Metab 33:593-600. 2008
  9. pmc Disparity in regional and systemic circulatory capacities: do they affect the regulation of the circulation?
    J A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s n, Las Palmas de Gran Canaria, Spain
    Acta Physiol (Oxf) 199:393-406. 2010
  10. doi request reprint The exercising heart at altitude
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, 35017, Las Palmas de Gran Canaria, Canary Islands, Spain
    Cell Mol Life Sci 66:3601-13. 2009

Collaborators

Detail Information

Publications48

  1. doi request reprint The response of human skeletal muscle tissue to hypoxia
    Carsten Lundby
    The Copenhagen Muscle Research Centre, Rigshospitalet Sect 7652, 2100, Copenhagen, Denmark
    Cell Mol Life Sci 66:3615-23. 2009
    ..On the other hand, combining hypoxia with exercise appears to improve some aspects of muscle O(2) transport and/or metabolism...
  2. doi request reprint Effects of strength training on muscle fatigue mapping from surface EMG and blood metabolites
    Mikel Izquierdo
    Studies, Research and Sport Medicine Center, Government of Navarra, Pamplona, Navarra, Spain
    Med Sci Sports Exerc 43:303-11. 2011
    ....
  3. pmc Iliopsoas and gluteal muscles are asymmetric in tennis players but not in soccer players
    Joaquin Sanchis-Moysi
    Physical Education Department, Las Palmas de Gran Canaria University, Las Palmas de Gran Canaria, Spain
    PLoS ONE 6:e22858. 2011
    ..To determine the volume and degree of asymmetry of iliopsoas (IL) and gluteal muscles (GL) in tennis and soccer players...
  4. doi request reprint Skeletal muscle signaling response to sprint exercise in men and women
    Teresa Fuentes
    Department of Physical Education, Campus Universitario de Tafira, University of Las Palmas de Gran Canaria, 35017 Las Palmas de Gran Canaria, Spain
    Eur J Appl Physiol 112:1917-27. 2012
    ..Marked increases in AMPKα, ACCβ, STAT3 and ERK phosphorylation were observed after a single 30-s all-out sprint (Wingate test) in the vastus lateralis...
  5. pmc Adiposity and age explain most of the association between physical activity and fitness in physically active men
    Jose A Serrano-Sanchez
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
    PLoS ONE 5:e13435. 2010
    ..To determine if there is an association between physical activity assessed by the short version of the International Physical Activity Questionnaire (IPAQ) and cardiorespiratory and muscular fitness...
  6. pmc Bone mass and the CAG and GGN androgen receptor polymorphisms in young men
    Amelia Guadalupe-Grau
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Islands, Spain
    PLoS ONE 5:e11529. 2010
    ..To determine whether androgen receptor (AR) CAG (polyglutamine) and GGN (polyglycine) polymorphisms influence bone mineral density (BMD), osteocalcin and free serum testosterone concentration in young men...
  7. pmc Skeletal muscle vasodilatation during maximal exercise in health and disease
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, Las Palmas de Gran Canaria, 35017, Spain
    J Physiol 590:6285-96. 2012
    ..This is likely to be critical for the maintenance of blood pressure in exercising patients with a limited heart pump capacity...
  8. ncbi request reprint Is pulmonary gas exchange during exercise in hypoxia impaired with the increase of cardiac output?
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, 35017, Spain
    Appl Physiol Nutr Metab 33:593-600. 2008
    ..It remains to be determined what is the influence of changes in cardiac output per se on pulmonary gas exchange during high-intensity exercise...
  9. pmc Disparity in regional and systemic circulatory capacities: do they affect the regulation of the circulation?
    J A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s n, Las Palmas de Gran Canaria, Spain
    Acta Physiol (Oxf) 199:393-406. 2010
    ..Finally, when approximately 80% of cardiac output is directed towards contracting skeletal muscle modest vasoconstriction in the active muscles can evoke marked changes in arterial pressure...
  10. doi request reprint The exercising heart at altitude
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, 35017, Las Palmas de Gran Canaria, Canary Islands, Spain
    Cell Mol Life Sci 66:3601-13. 2009
    ..Special emphasis is put on the cardioprotective effects of chronic hypoxia...
  11. pmc On the mechanisms that limit oxygen uptake during exercise in acute and chronic hypoxia: role of muscle mass
    Jose A L Calbet
    The Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen N, Denmark
    J Physiol 587:477-90. 2009
    ....
  12. ncbi request reprint Air to muscle O2 delivery during exercise at altitude
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Spain
    High Alt Med Biol 10:123-34. 2009
    ..In summary, hypoxia reduces Vo2max because it limits O2 diffusion in the lung...
  13. doi request reprint Increased oxidative stress and anaerobic energy release, but blunted Thr172-AMPKα phosphorylation, in response to sprint exercise in severe acute hypoxia in humans
    David Morales-Alamo
    Department of Physical Education, University of Las Palmas de Gran Canaria Campus Universitario de Tafira Las Palmas de Gran Canaria, Spain
    J Appl Physiol (1985) 113:917-28. 2012
    ..Collectively, our results indicate that the signaling response to sprint exercise in human skeletal muscle is altered in severe acute hypoxia, which abrogated Thr(172)-AMPKα phosphorylation, likely due to lower LKB1 activation by SIRT1...
  14. doi request reprint Critical role for free radicals on sprint exercise-induced CaMKII and AMPKα phosphorylation in human skeletal muscle
    David Morales-Alamo
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, Las Palmas de Gran Canaria 35017, Canary Island, Spain
    J Appl Physiol (1985) 114:566-77. 2013
    ..Sprint performance, muscle metabolism, and AMP-to-ATP and NAD(+)-to-NADH.H(+) ratios are not affected by the acute ingestion of antioxidants...
  15. ncbi request reprint Plasma volume expansion does not increase maximal cardiac output or VO2 max in lowlanders acclimatized to altitude
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, 35010 Canary Islands, Spain
    Am J Physiol Heart Circ Physiol 287:H1214-24. 2004
    ..Furthermore, hemodilution caused by PV expansion at altitude is compensated for by increased systemic O2 extraction with similar peak muscular O2 delivery, such that maximal exercise capacity is unaffected...
  16. pmc During hypoxic exercise some vasoconstriction is needed to match O2 delivery with O2 demand at the microcirculatory level
    Carsten Lundby
    Copenhagen Muscle Research Center, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen Ø, Denmark
    J Physiol 586:123-30. 2008
    ..Peak cardiac output at altitude is not limited by excessive mean arterial pressure. Exercising leg .VO(2peak) is not limited by restricted vasodilatation in the altitude-acclimatized human...
  17. doi request reprint Is sprint exercise a leptin signaling mimetic in human skeletal muscle?
    Borja Guerra
    Department of Physical Education, University of Las Palmas de Gran Canaria, Spain
    J Appl Physiol (1985) 111:715-25. 2011
    ..In conclusion, sprint exercise performed under fasting conditions is a leptin signaling mimetic in human skeletal muscle...
  18. ncbi request reprint Effects of weight lifting training combined with plyometric exercises on physical fitness, body composition, and knee extension velocity during kicking in football
    Jorge Perez-Gomez
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Island, Spain
    Appl Physiol Nutr Metab 33:501-10. 2008
    ..In conclusion, 6 weeks of strength training combining weight lifting and plyometric exercises results in significant improvement of kicking performance, as well as other physical capacities related to success in football (soccer)...
  19. doi request reprint Bone and lean mass inter-arm asymmetries in young male tennis players depend on training frequency
    Joaquin Sanchis-Moysi
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s n, Las Palmas de Gran Canaria, 35017 Canary Island, Spain
    Eur J Appl Physiol 110:83-90. 2010
    ..Young tennis players have increased BMC, bone area and lean mass in dominant arm, which magnitude depends on the number of weekly hours devoted to tennis...
  20. pmc Gender dimorphism in skeletal muscle leptin receptors, serum leptin and insulin sensitivity
    Borja Guerra
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s n, Las Palmas de Gran Canaria, Spain
    PLoS ONE 3:e3466. 2008
    ..The circulating form of the leptin receptor can not be used as a surrogate measure of the amount of leptin receptors expressed in skeletal muscles...
  21. doi request reprint Osteocalcin as a negative regulator of serum leptin concentration in humans: insight from triathlon competitions
    Amelia Guadalupe-Grau
    Department of Physical Education, University of Las Palmas de Gran Canaria, 35017 Las Palmas de Gran Canaria, Canary Island, Spain
    Eur J Appl Physiol 110:635-43. 2010
    ..This study provides evidence for osteocalcin as a negative regulator of serum leptin in humans...
  22. ncbi request reprint Pulmonary gas exchange at maximal exercise in Danish lowlanders during 8 wk of acclimatization to 4,100 m and in high-altitude Aymara natives
    Carsten Lundby
    The Copenhagen Muscle Research Centre, Rigshospitalet, Sect 7652, 9 Blegdamsvej, DK 2100 Copenhagen Ø, Denmark
    Am J Physiol Regul Integr Comp Physiol 287:R1202-8. 2004
    ..4 mmHg). In conclusion, lowlanders substantially improve pulmonary gas exchange with acclimatization, but even acclimatization for 8 wk is insufficient to achieve levels reached by high-altitude natives...
  23. ncbi request reprint SIRT1, AMP-activated protein kinase phosphorylation and downstream kinases in response to a single bout of sprint exercise: influence of glucose ingestion
    Borja Guerra
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, 35017, Las Palmas de Gran Canaria, Canary Islands, Spain
    Eur J Appl Physiol 109:731-43. 2010
    ..In conclusion, glucose ingestion prior to a sprint exercise profoundly affects Thr(172)-AMPKalpha phosphorylation and its downstream signaling during the recovery period...
  24. doi request reprint Muscle hypertrophy and increased expression of leptin receptors in the musculus triceps brachii of the dominant arm in professional tennis players
    Hugo Olmedillas
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s n, 35017 Las Palmas de Gran Canaria, Canary Island, Spain
    Eur J Appl Physiol 108:749-58. 2010
    ..Our findings are also consistent with a role of leptin signalling in muscle hypertrophy in healthy humans...
  25. ncbi request reprint Cardiac output and leg and arm blood flow during incremental exercise to exhaustion on the cycle ergometer
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Spain
    J Appl Physiol (1985) 103:969-78. 2007
    ....
  26. doi request reprint Androgen receptor gene polymorphisms lean mass and performance in young men
    Amelia Guadalupe-Grau
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafi ra s n, Las Palmas de Gran Canaria, 35017, Spain
    Br J Sports Med 45:95-100. 2011
    ..11, p=0.06). In summary, the lengths of CAG and GGN repeat of the AR gene do not appear to influence lean mass or fitness in young men...
  27. pmc Chronic hypoxia increases blood pressure and noradrenaline spillover in healthy humans
    Jose A L Calbet
    The Copenhagen Muscle Research Centre, Copenhagen, Denmark
    J Physiol 551:379-86. 2003
    ....
  28. doi request reprint Androgen receptor gene polymorphisms and the fat-bone axis in young men and women
    Jesú Gustavo Ponce-González
    Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s n, Las Palmas de Gran Canaria, Spain
    J Androl 33:644-50. 2012
    ..In young women, GGN length is positively associated with adiposity, leptin, and osteocalcin...
  29. ncbi request reprint Effects of eccentric exercise on cycling efficiency
    Joaquin Sanchis Moysi
    Departamento de Educacion Fisica, Campus Universitario de Tafira, Las Palmas de Gran Canaria, Canary Islands, Spain
    Can J Appl Physiol 30:259-75. 2005
    ..We conclude that eccentric exercise does not alter or has only a marginal effect on gross cycling efficiency even in presence of marked muscle soreness...
  30. ncbi request reprint Role of muscle mass on sprint performance: gender differences?
    Jorge Perez-Gomez
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Island, Spain
    Eur J Appl Physiol 102:685-94. 2008
    ..Although, the peak power generating capability of the muscle is similar in males and females, muscle mass only partially explains the gender difference in running sprints, even when expressed as a percentage of the whole body mass...
  31. ncbi request reprint Reductions in systemic and skeletal muscle blood flow and oxygen delivery limit maximal aerobic capacity in humans
    Jose Gonzalez-Alonso
    Copenhagen Muscle Research Centre, Rigshospitalet, University of Copenhagen, Denmark
    Circulation 107:824-30. 2003
    ..Severe heat stress drastically reduces VO2max, but the mechanisms have never been studied...
  32. pmc Muscle hypertrophy in prepubescent tennis players: a segmentation MRI study
    Joaquin Sanchis-Moysi
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
    PLoS ONE 7:e33622. 2012
    ..To asses if tennis at prepubertal age elicits the hypertrophy of dominant arm muscles...
  33. ncbi request reprint High femoral bone mineral density accretion in prepubertal soccer players
    German Vicente-Rodriguez
    Department of Physical Education, University of Las Palmas de Gran Canaria, Spain
    Med Sci Sports Exerc 36:1789-95. 2004
    ..To determine the effect of physical activity on bone mineral accrual during growth in prepuberal boys...
  34. doi request reprint Exercise and bone mass in adults
    Amelia Guadalupe-Grau
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Canary Islands, Spain
    Sports Med 39:439-68. 2009
    ..Additional randomized controlled trials are needed to determine the most efficient training loads depending on age, sex, current bone mass and training history for improvement of bone mass...
  35. doi request reprint Repeated muscle biopsies through a single skin incision do not elicit muscle signaling, but IL-6 mRNA and STAT3 phosphorylation increase in injured muscle
    Borja Guerra
    Departamento de Educacion Fisica, Campus Universitario de Tafira, 35017 Las Palmas de Gran Canaria, Canary Island, Spain
    J Appl Physiol (1985) 110:1708-15. 2011
    ..STAT3 phosphorylation is an early event in the healing response to muscle injury, probably mediated by the autocrine production of IL-6...
  36. ncbi request reprint Importance of hemoglobin concentration to exercise: acute manipulations
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Spain
    Respir Physiol Neurobiol 151:132-40. 2006
    ..V(O(2)(max) during exercise in acute hypoxia. Likewise, reducing [Hb] in altitude-acclimatized humans to pre-acclimatization values has no effect on (.)V(O(2)(max) during exercise in hypoxia...
  37. doi request reprint Leptin signaling in skeletal muscle after bed rest in healthy humans
    Borja Guerra
    Departamento de Educacion Fisica, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira, 35017, Las Palmas de Gran Canaria, Canary Island, Spain
    Eur J Appl Physiol 114:345-57. 2014
    ..This study aimed at determining the effects of bed rest on the skeletal muscle leptin signaling system...
  38. ncbi request reprint Effects of recovery mode on performance, O2 uptake, and O2 deficit during high-intensity intermittent exercise
    Cecilia Dorado
    Department of Physical Education, University of Las Palmas de Gran Canaria, Canary Islands, Spain
    Can J Appl Physiol 29:227-44. 2004
    ..Therefore, this study shows that active recovery facilitates performance by increasing aerobic contribution to the whole energy yield turnover during high-intensity intermittent exercise...
  39. doi request reprint Marked effects of Pilates on the abdominal muscles: a longitudinal magnetic resonance imaging study
    Cecilia Dorado
    Physical Education Department, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
    Med Sci Sports Exerc 44:1589-94. 2012
    ..The study's purpose was to analyze the effects of Pilates on the volume of the rectus abdominis (RA), obliques, and transversus abdominis, with the last two considered conjointly (OT)...
  40. doi request reprint Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans
    Robert Boushel
    The Copenhagen Muscle Research Centre, Copenhagen, Denmark
    Mitochondrion 11:303-7. 2011
    ..The findings reveal an excess capacity of muscle mitochondrial respiratory rate over O(2) delivery by the circulation in the cascade defining maximal oxidative rate in humans...
  41. pmc The rate of fatigue accumulation as a sensed variable
    Jose A L Calbet
    Department of Physical Education, University of Las Palmas de Gran Canaria, Spain
    J Physiol 575:688-9. 2006
  42. pmc Large asymmetric hypertrophy of rectus abdominis muscle in professional tennis players
    Joaquin Sanchis-Moysi
    Department of Physical Education, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
    PLoS ONE 5:e15858. 2010
    ..To determine the volume and degree of asymmetry of the musculus rectus abdominis (RA) in professional tennis players...
  43. ncbi request reprint Leptin receptors in human skeletal muscle
    Borja Guerra
    Department of Physical Education, University of Las Palmas de Gran Canaria, Canary Island, Spain
    J Appl Physiol (1985) 102:1786-92. 2007
    ..The amount of 170-kDa protein appears to be independent of the basal concentration of leptin in serum...
  44. doi request reprint Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest
    Kristian Kiilerich
    August Krogh Bldg, Dept of Biology, Universitetsparken 13, 2100 Copenhagen, Denmark
    J Appl Physiol (1985) 111:751-7. 2011
    ..This suggests that exercise-induced PDH regulation in skeletal muscle is maintained in glucose-intolerant (e.g., insulin resistant) individuals...
  45. pmc Skeletal muscle myofibrillar and sarcoplasmic protein synthesis rates are affected differently by altitude-induced hypoxia in native lowlanders
    Lars Holm
    Department of Orthopaedic Surgery M and Institute of Sports Medicine, Bispebjerg Hospital, and Faculty of Health Sciences, Center of Healthy Ageing, University of Copenhagen, Copenhagen, Denmark
    PLoS ONE 5:e15606. 2010
    ..These changed responses may lead to divergent adaptation over the course of prolonged exposure...
  46. ncbi request reprint Skeletal muscle mitochondrial function and exercise capacity in HIV-infected patients with lipodystrophy and elevated p-lactate levels
    Birgit T Røge
    Department of Infectious Diseases, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    AIDS 16:973-82. 2002
    ..To investigate the skeletal muscle mitochondrial function in HIV-infected patients with lipodystrophy or elevated p-lactate levels...
  47. ncbi request reprint Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans
    Jose A L Calbet
    Copenhagen Muscle Research Center, Rigshospitalet, Copenhagen, Denmark
    Eur J Nutr 43:127-39. 2004
    ..The influence of protein fractionation on gastric emptying and rate of appearance of their constituent amino acids in peripheral blood remains unknown...
  48. ncbi request reprint Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans
    Jose A L Calbet
    Copenhagen Muscle Research Center, Rigshospitalet, Section 7652, Blegdamsvej 9, Denmark
    J Nutr 132:2174-82. 2002
    ..The combined administration of glucose and peptide hydrolysates stimulates a synergistic release of insulin, regardless of the protein source...