Helen Bygrave

Summary

Publications

  1. pmc Antiretroviral therapy outcomes among adolescents and youth in rural Zimbabwe
    Helen Bygrave
    Southern Africa Medical Unit, Medecins Sans Frontieres, Cape Town, South Africa
    PLoS ONE 7:e52856. 2012
  2. doi request reprint Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    J Acquir Immune Defic Syndr 56:e75-8. 2011
  3. pmc Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    PLoS ONE 6:e17609. 2011
  4. doi request reprint Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho
    Guillaume Jouquet
    Medecins Sans Frontieres, Morija, Lesotho
    J Acquir Immune Defic Syndr 58:e68-74. 2011
  5. pmc Trends in loss to follow-up among migrant workers on antiretroviral therapy in a community cohort in Lesotho
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    PLoS ONE 5:e13198. 2010
  6. doi request reprint Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho
    Nathan Ford
    Medecins Sans Frontieres, University of Cape Town, South Africa
    AIDS 24:2645-50. 2010
  7. doi request reprint Feasibility and benefits of scaling up antiretroviral treatment provision with the 2010 WHO antiretroviral therapy guidelines in rural Lesotho
    Helen Bygrave
    South African Medical Unit, Medecins Sans Frontieres, PO Box 27401, Rhine Road, Sea Point 8050, Cape Town, South Africa
    Int Health 4:170-5. 2012
  8. pmc Antiretroviral treatment outcomes from a nurse-driven, community-supported HIV/AIDS treatment programme in rural Lesotho: observational cohort assessment at two years
    Rachel Cohen
    Medecins Sans Frontieres, Morija, Lesotho
    J Int AIDS Soc 12:23. 2009

Collaborators

  • Nathan Ford
  • Katharina Kranzer
  • Gilles Van Cutsem
  • Guillaume Jouquet
  • Eric Goemaere
  • Lipontso Makakole
  • Katherine Hilderbrand
  • Natalie Vlahakis
  • Rachel Cohen
  • Laurent Gadot
  • Susan Cleary
  • Janice Lee
  • Laura Triviño
  • Prinitha Pillay
  • Sharonann Lynch
  • Peter Saranchuk
  • Louise Knight
  • Evi Eggers

Detail Information

Publications8

  1. pmc Antiretroviral therapy outcomes among adolescents and youth in rural Zimbabwe
    Helen Bygrave
    Southern Africa Medical Unit, Medecins Sans Frontieres, Cape Town, South Africa
    PLoS ONE 7:e52856. 2012
    ..70, 95%CI 1.62-4.52). This study highlights the need for adapted adherence support and service delivery models for both adolescents and young adults...
  2. doi request reprint Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    J Acquir Immune Defic Syndr 56:e75-8. 2011
    ..We report on outcomes and toxicities among patients on these different regimens in a routine treatment cohort in Lesotho...
  3. pmc Renal safety of a tenofovir-containing first line regimen: experience from an antiretroviral cohort in rural Lesotho
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    PLoS ONE 6:e17609. 2011
    ..We report prevalence of abnormal renal function at baseline and factors associated with abnormal renal function from a community cohort in Lesotho...
  4. doi request reprint Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho
    Guillaume Jouquet
    Medecins Sans Frontieres, Morija, Lesotho
    J Acquir Immune Defic Syndr 58:e68-74. 2011
    ..Latest World Health Organization guidelines recommend shifting away from Stavudine (d4T)-based regimens due to severe side effects. However, widespread replacement of d4T by Tenofovir (TDF) or Zidovudine (AZT) is hampered by cost concerns...
  5. pmc Trends in loss to follow-up among migrant workers on antiretroviral therapy in a community cohort in Lesotho
    Helen Bygrave
    Medecins Sans Frontieres, Morija, Lesotho
    PLoS ONE 5:e13198. 2010
    ..We assessed rates of loss to follow-up for migrant workers compared with non-migrant workers in a routine treatment programme in Morjia, Lesotho...
  6. doi request reprint Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho
    Nathan Ford
    Medecins Sans Frontieres, University of Cape Town, South Africa
    AIDS 24:2645-50. 2010
    ..Lesotho has supported earlier initiation since 2008. We assessed outcomes comparing early (CD4 cell counts >200 cells/μl) and late (CD4 cell counts ≤200 cells/μl) initiation...
  7. doi request reprint Feasibility and benefits of scaling up antiretroviral treatment provision with the 2010 WHO antiretroviral therapy guidelines in rural Lesotho
    Helen Bygrave
    South African Medical Unit, Medecins Sans Frontieres, PO Box 27401, Rhine Road, Sea Point 8050, Cape Town, South Africa
    Int Health 4:170-5. 2012
    ..This experience demonstrates that, despite limited resources, it was feasible to provide a standard of care similar to that of western guidelines and that these changes were supportive of simplified patient management. ..
  8. pmc Antiretroviral treatment outcomes from a nurse-driven, community-supported HIV/AIDS treatment programme in rural Lesotho: observational cohort assessment at two years
    Rachel Cohen
    Medecins Sans Frontieres, Morija, Lesotho
    J Int AIDS Soc 12:23. 2009
    ..abstract:..