Attempted control of hyperglycemia during cardiopulmonary bypass fails to improve neurologic or neurobehavioral outcomes in patients without diabetes mellitus undergoing coronary artery bypass graftingJohn Butterworth
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
J Thorac Cardiovasc Surg 130:1319. 2005
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- Rapid disappearance of protamine in adults undergoing cardiac operation with cardiopulmonary bypass
John Butterworth
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1009, USA
Ann Thorac Surg 74:1589-95. 2002
..Despite long use of protamine in cardiac operations, neither protamine concentrations nor pharmacokinetics have been reported in patients...
- Intraoperative insulin therapy does not reduce the need for inotropic or antiarrhythmic therapy after cardiopulmonary bypass
Leanne Groban
Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA
J Cardiothorac Vasc Anesth 16:405-12. 2002
..The lack of benefit may be due to the inability to prevent hyperglycemia during the physiologic stress of CPB or a tribute to the effectiveness of modern myocardial preservation techniques...
- Does local anesthetic stereoselectivity or structure predict myocardial depression in anesthetized canines?
Leanne Groban
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Reg Anesth Pain Med 27:460-8. 2002
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- Failure of argatroban anticoagulation during off-pump coronary artery bypass surgery
Mark A Cannon
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Ann Thorac Surg 77:711-3. 2004
..Unfortunately, our experience was that argatroban does not provide adequate anticoagulation during off-pump coronary bypass surgery, even when the ACT is maintained at more than 380 sec...
- Intrathecal morphine reduces infarct size in a rat model of ischemia-reperfusion injury
Leanne Groban
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157 1009, USA
Anesth Analg 98:903-9, table of contents. 2004
..In anesthetized rats subjected to ischemia-reperfusion injury, we show that very small doses of intrathecal morphine reduce infarct size in rats, and this benefit is as great as that provided by much larger doses of IV morphine...
- Local anesthetic-induced cardiac toxicity: a survey of contemporary practice strategies among academic anesthesiology departments
William Corcoran
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1009, USA
Anesth Analg 103:1322-6. 2006
..We conclude that there are differences in the management and preparedness for treatment of LA toxicity among institutions, but the safety implications of these differences are undetermined...
- Dexmedetomidine-induced sedation in volunteers decreases regional and global cerebral blood flow
Richard C Prielipp
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
Anesth Analg 95:1052-9, table of contents. 2002
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- Perioperative management of chronic heart failure
Leanne Groban
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
Anesth Analg 103:557-75. 2006
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- Ulnar nerve injury and perioperative arm positioning
Richard C Prielipp
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
Anesthesiol Clin North America 20:589-603. 2002
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- Polypoid hyperplasia of the larynx misdiagnosed as a malpositioned laryngeal mask airway
John Butterworth
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1009, USA
Anesth Analg 99:1570-2; table of contents. 2004
..Polypoid hyperplasia of the vocal cords, associated with smoking, reflux, and vocal cord abuse, results in inflammation and edema. This condition can produce partial airway obstruction during positive pressure ventilation...
- Pulmonary artery catheter placement for elective coronary artery bypass grafting: before or after anesthetic induction?
Michael H Wall
Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
Anesth Analg 94:1409-15, table of contents. 2002
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- Clinical trial of the neuroprotectant clomethiazole in coronary artery bypass graft surgery: a randomized controlled trial
Robert S Kong
Health Psychology Unit, Academic Department of Psychiatry and Behavioural Sciences, Reta Lila Weston Institute of Neurological Studies, Royal Free and University College London Medical School, United Kingdom
Anesthesiology 97:585-91. 2002
..There was no difference between the clomethiazole and placebo group in the postoperative change in neuropsychological test scores. CONCLUSION: Clomethiazole did not improve cerebral outcome following coronary artery bypass surgery...
- Pharmacokinetics of tranexamic acid during cardiopulmonary bypass
Noreen P Dowd
Division of Cardiac Anesthesia and Intensive Care, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
Anesthesiology 97:390-9. 2002
..Variation in TA efficacy from study to study and confusion about the optimal duration of TA treatment may be the result of dosing techniques that do not maintain stable, therapeutic TA concentrations...
- Dobutamine: too dangerous for "routine" administration?
John Butterworth
Anesthesiology 108:973-4. 2008
