Rafal Butowt

Summary

Publications

  1. ncbi request reprint Conventional kinesin-I motors participate in the anterograde axonal transport of neurotrophins in the visual system
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, USA
    J Neurosci Res 85:2546-56. 2007
  2. ncbi request reprint Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system
    Rafal Butowt
    Department of Physiology and Cell Biology, Mail Stop 352, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cell Neurosci 31:97-108. 2006
  3. ncbi request reprint Anterograde axonal transport of BDNF and NT-3 by retinal ganglion cells: roles of neurotrophin receptors
    Rafal Butowt
    Department of Physiology and Cell Biology, Mailstop 352, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cell Neurosci 29:11-25. 2005
  4. pmc Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Neurosci 29:10715-29. 2009
  5. ncbi request reprint Synaptic targeting of retrogradely transported trophic factors in motoneurons: comparison of glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor, and cardiotrophin-1 with tetanus toxin
    Howard B Rind
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Neurosci 25:539-49. 2005
  6. ncbi request reprint Anterograde axonal transport of chicken cellular prion protein (PrPc) in vivo requires its N-terminal part
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada, School of Medicine, Reno, Nevada, USA
    J Neurosci Res 85:2567-79. 2007
  7. ncbi request reprint Presynaptic neurotrophin-3 increases the number of tectal synapses, vesicle density, and number of docked vesicles in chick embryos
    Xiaoxia Wang
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Comp Neurol 458:62-77. 2003
  8. ncbi request reprint Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Eur J Neurosci 17:673-80. 2003
  9. ncbi request reprint GDNF increases the survival of developing oculomotor neurons through a target-derived mechanism
    Jennifer Chen
    Department of Physiology and Cell Biology, MS 352, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cell Neurosci 24:41-56. 2003
  10. ncbi request reprint Mechanisms of the release of anterogradely transported neurotrophin-3 from axon terminals
    Xiaoxia Wang
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Neurosci 22:931-45. 2002

Research Grants

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Conventional kinesin-I motors participate in the anterograde axonal transport of neurotrophins in the visual system
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, USA
    J Neurosci Res 85:2546-56. 2007
    ..2000] J Neurosci 20:6374-6384). These data indicate that kinesin-I is a protein motor that participates in the anterograde axonal transport of neurotrophins in the chicken and mouse visual pathways...
  2. ncbi request reprint Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system
    Rafal Butowt
    Department of Physiology and Cell Biology, Mail Stop 352, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cell Neurosci 31:97-108. 2006
    ..This may provide an additional, novel mechanism for prion protein to spread among neurons...
  3. ncbi request reprint Anterograde axonal transport of BDNF and NT-3 by retinal ganglion cells: roles of neurotrophin receptors
    Rafal Butowt
    Department of Physiology and Cell Biology, Mailstop 352, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cell Neurosci 29:11-25. 2005
    ..Thus, neither BDNF nor NT-3 utilizes p75 for anterograde transport in adult rodent RGCs, while anterograde NT-3 transport requires the p75 receptor in embryonic chicken RGCs...
  4. pmc Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Neurosci 29:10715-29. 2009
    ....
  5. ncbi request reprint Synaptic targeting of retrogradely transported trophic factors in motoneurons: comparison of glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor, and cardiotrophin-1 with tetanus toxin
    Howard B Rind
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Neurosci 25:539-49. 2005
    ..CT-1, however, follows a strict degradation pathway after retrograde transport to the soma. Synaptic and transcytotic trafficking thus are restricted to particular neurotrophic factors such as GDNF and BDNF...
  6. ncbi request reprint Anterograde axonal transport of chicken cellular prion protein (PrPc) in vivo requires its N-terminal part
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada, School of Medicine, Reno, Nevada, USA
    J Neurosci Res 85:2567-79. 2007
    ..These data indicate that the N-terminal half of chicken PrP(c) contains the necessary information to drive the internalization and subsequent sorting of extracellular PrP(c) in RGCs soma into the anterograde axonal transport pathway...
  7. ncbi request reprint Presynaptic neurotrophin-3 increases the number of tectal synapses, vesicle density, and number of docked vesicles in chick embryos
    Xiaoxia Wang
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Comp Neurol 458:62-77. 2003
    ..We conclude that anterogradely transported NT-3 affects synapse strength in a way that differs from that of presumably postsynaptic-derived BDNF...
  8. ncbi request reprint Connecting the dots: trafficking of neurotrophins, lectins and diverse pathogens by binding to the neurotrophin receptor p75NTR
    Rafal Butowt
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA
    Eur J Neurosci 17:673-80. 2003
    ....
  9. ncbi request reprint GDNF increases the survival of developing oculomotor neurons through a target-derived mechanism
    Jennifer Chen
    Department of Physiology and Cell Biology, MS 352, University of Nevada School of Medicine, Reno, NV 89557, USA
    Mol Cell Neurosci 24:41-56. 2003
    ..Thus, one GDNF family member acts as a muscle-derived retrograde survival factor, whereas another one has distinct functions on neurite outgrowth...
  10. ncbi request reprint Mechanisms of the release of anterogradely transported neurotrophin-3 from axon terminals
    Xiaoxia Wang
    Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA
    J Neurosci 22:931-45. 2002
    ..The data provide insight in the mechanisms of anterograde neurotrophins as synaptic modulators...

Research Grants2

  1. The Role of p75 Receptor in Tetanus Toxin Transport
    Rafal Butowt; Fiscal Year: 2005
    ..1992; Schneider et al., 2000; Schiavo et al., 2000; Bordet et al., 2001; Kissa et al., 2002). ..
  2. Analysis of Kinesins Mediating Neurotrophin Transport
    Rafal Butowt; Fiscal Year: 2006
    ..abstract_text> ..