Visual backward-masking deficits in schizophrenia: relationship to visual pathway function and symptomatologyPamela D Butler
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
Schizophr Res 59:199-209. 2003
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Subcortical visual dysfunction in schizophrenia drives secondary cortical impairmentsPamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Brain 130:417-30. 2007
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- Sensory contributions to impaired emotion processing in schizophrenia
Pamela D Butler
Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA
Schizophr Bull 35:1095-107. 2009
..These results provide evidence for a contribution of impaired early-stage visual processing in emotion recognition deficits in schizophrenia and suggest that a bottom-up approach to remediation may be effective...
- Impairments in generation of early-stage transient visual evoked potentials to magno- and parvocellular-selective stimuli in schizophrenia
Isaac Schechter
Nathan Kline Institute, Program in Cognitive Neuroscience and Schizophrenia, Orangeburg, NY 10962, USA
Clin Neurophysiol 116:2204-15. 2005
..Further, between-group differences in visual acuity may influence VEP results, even for subjects with 'normal' vision (20/32 or better)...
Impaired visual object processing across an occipital-frontal-hippocampal brain network in schizophrenia: an integrated neuroimaging studyPejman Sehatpour
Conte Center for Schizophrenia Research, Cognitive Neurophysiology Laboratory, Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
Arch Gen Psychiatry 67:772-82. 2010
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- Early-stage visual processing and cortical amplification deficits in schizophrenia
Pamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Arch Gen Psychiatry 62:495-504. 2005
..Investigating magnocellular dysfunction in schizophrenia therefore permits evaluation of underlying etiologic hypotheses...
- Magnocellular pathway impairment in schizophrenia: evidence from functional magnetic resonance imaging
Antigona Martinez
Nathan S Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
J Neurosci 28:7492-500. 2008
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- Visual white matter integrity in schizophrenia
Pamela D Butler
Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg NY, 10962, USA
Am J Psychiatry 163:2011-3. 2006
..Patients with schizophrenia have visual-processing deficits. This study examines visual white matter integrity as a potential mechanism for these deficits...
- What's in a face? Effects of stimulus duration and inversion on face processing in schizophrenia
Pamela D Butler
Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
Schizophr Res 103:283-92. 2008
..Similar inversion effects for face part and spacing for both groups suggest that they are using the same holistic face processing mechanism...
- Seeing the world dimly: the impact of early visual deficits on visual experience in schizophrenia
Joshua T Kantrowitz
Department of Life Sciences, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY, USA
Schizophr Bull 35:1085-94. 2009
..01). This study replicates and expands upon previous findings with visual illusions. Our results offer a unifying explanation for disparate studies and suggest that deficits in early sensory gain affect subsequent integrative processes...
- Has an important test been overlooked? Closure flexibility in schizophrenia
Pamela D Butler
Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
Schizophr Res 118:20-5. 2010
..In addition, the CFT is a brief, easy to administer alphabet-independent, paper-and-pencil test with established psychometric properties that may be useful as an index of the sustained visual attention construct in schizophrenia...
- Dysfunction of early-stage visual processing in schizophrenia: harmonic analysis
Dongsoo Kim
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Schizophr Res 76:55-65. 2005
..Early sensory deficits may lead to impairments in subsequent stages of processing...
- Consequences of magnocellular dysfunction on processing attended information in schizophrenia
Antigona Martinez
Nathan Kline Institute for Psychiatric Research, Schizophrenia Research Division Orangeburg, NY 10962, USA
Cereb Cortex 22:1282-93. 2012
..These findings suggest that impaired sensory processing of magnocellularly biased stimuli lead to impairments in the effective processing of attended stimuli, even when the attention control systems themselves are intact...
- Reading impairment and visual processing deficits in schizophrenia
Nadine Revheim
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 87:238-45. 2006
..Findings related to symptoms, functioning and recommendations for reading ability assessment are discussed...
- Magnocellular contributions to impaired motion processing in schizophrenia
Dongsoo Kim
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, New York 10962, USA
Schizophr Res 82:1-8. 2006
..Further, this study supports and extends prior reports of impaired motion processing in schizophrenia, and indicates significant bottom-up contributions to higher-order cognitive impairments...
- Early sensory contributions to contextual encoding deficits in schizophrenia
Elisa C Dias
Center for Translational Schizophrenia Research, The Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Arch Gen Psychiatry 68:654-64. 2011
..Event-related potentials (ERP) provide an objective index of brain function and can be used to evaluate brain substrates underlying impaired cognition in schizophrenia...
- Visual perception and its impairment in schizophrenia
Pamela D Butler
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Biol Psychiatry 64:40-7. 2008
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- Sensory contributions to impaired prosodic processing in schizophrenia
David I Leitman
Program in Cognitive Neuroscience and Schizophrenia, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA
Biol Psychiatry 58:56-61. 2005
..The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia...
- Brain morphometry using diffusion-weighted magnetic resonance imaging: application to schizophrenia
Babak A Ardekani
Center for Advanced Brain Imaging, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, USA
Neuroreport 16:1455-9. 2005
..Affected areas included the bilateral insular cortex, hippocampus, temporal lobe, and occipital areas. These results largely concur with previous findings of cortical volume deficits in schizophrenia...
- A new dimension of sensory dysfunction: stereopsis deficits in schizophrenia
Isaac Schechter
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA
Biol Psychiatry 60:1282-4. 2006
..Early visual processing has been shown to be especially impaired. This article investigates the integrity of binocular depth perception (stereopsis) in schizophrenia...
- Spatial localization deficits and auditory cortical dysfunction in schizophrenia
Megan A Perrin
Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, United States
Schizophr Res 124:161-8. 2010
..Variability of sound localization has not previously been studied in schizophrenia...
- Amplitude of low-frequency oscillations in schizophrenia: a resting state fMRI study
Matthew J Hoptman
Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 117:13-20. 2010
..These results suggest LFO abnormalities in schizophrenia. The implication of these abnormalities for schizophrenic symptomatology is further discussed...
- Reduction in tonal discriminations predicts receptive emotion processing deficits in schizophrenia and schizoaffective disorder
Joshua T Kantrowitz
Schizophrenia Research Center, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Bull 39:86-93. 2013
..Schizophrenia patients show decreased ability to identify emotion based upon tone of voice (voice emotion recognition), along with deficits in basic auditory processing. Interrelationship among these measures is poorly understood...
- Comparison of psychophysical, electrophysiological, and fMRI assessment of visual contrast responses in patients with schizophrenia
Daniel J Calderone
Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA Department of Psychiatry, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA Department of Psychology, The Graduate Center, City University of New York, 365 Fifth Avenue, New York, NY 10016, USA Electronic address
Neuroimage 67:153-62. 2013
..These results indicate dissociation between the fMRI measures and the psychophysical/ssVEP measures. These latter measures appear to have greater value for the functional assessment of the contrast deficits explored here...
- Magnocellular and parvocellular contributions to backward masking dysfunction in schizophrenia
Isaac Schechter
Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Schizophr Res 64:91-101. 2003
..Furthermore, deficits of letter identification, including those of P targets, may also reflect impairment of the M pathway given the priming function of the dorsal stream...
- Perceptual measurement in schizophrenia: promising electrophysiology and neuroimaging paradigms from CNTRICS
Pamela D Butler
Nathan Kline Institute for Psychiatric Research, Schizophrenia Research Center, Orangeburg, NY, USA
Schizophr Bull 38:81-91. 2012
..This manuscript describes the ways in which each of these tasks met the criteria used in the breakout group to evaluate and recommend tasks for further development...
- DTI and impulsivity in schizophrenia: a first voxelwise correlational analysis
Matthew J Hoptman
Division of Clinical Research, Nathan Kline Institute, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
Neuroreport 15:2467-70. 2004
..These areas may comprise a fronto-temporo-limbic circuit that modulates impulsivity. The voxelwise correlation method can serve as a hypothesis-generation method for relating target behaviors to their underlying neural networks...
- Perceptual organization by proximity and similarity in schizophrenia
Daniel D Kurylo
Psychology Department, Brooklyn College CUNY, 2900 Bedford Avenue, Brooklyn, NY 11210, USA
Schizophr Res 95:205-14. 2007
..Although this study did not directly investigate the physiological correlates underlying perceptual impairments, these results are consistent with a theory of impaired lateral connections within visual cortical areas in schizophrenia...
- Voxelwise correlational analyses of white matter integrity in multiple cognitive domains in schizophrenia
Kelvin O Lim
Department of Psychiatry, University of Minnesota, Minneapolis 55455, USA
Am J Psychiatry 163:2008-10. 2006
..In each case, better performance on these tasks was associated with higher levels of fractional anisotropy in task-relevant regions...
- Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding
Abraham A Palmer
Department of Pharmacology, University of California San Diego, La Jolla, CA 92093, USA
Brain Res 996:193-201. 2004
..This animal model may be useful for the investigation of neurodevelopmental changes that are associated with schizophrenia in humans...
