Philip S Burton

Summary

Publications

  1. ncbi Solubility and permeability measurement and applications in drug discovery
    Philip S Burton
    ADMETRX Inc, 4717 Campus Drive, Suite 600, Kalamazoo, MI 49008, USA
    Comb Chem High Throughput Screen 13:101-11. 2010
  2. ncbi Predicting oral absorption of drugs: a case study with a novel class of antimicrobial agents
    Allen R Hilgers
    Drug Absorption and Transport, Global Pharmaceutical Sciences, Pharmacia, Kalamazoo, 49007, USA
    Pharm Res 20:1149-55. 2003
  3. ncbi Predicting drug absorption: how nature made it a difficult problem
    Philip S Burton
    Drug Absorption and Transport, Pharmacia, Kalamazoo, Michigan 49007, USA
    J Pharmacol Exp Ther 303:889-95. 2002

Collaborators

  • Jay T Goodwin
  • Allen R Hilgers
  • Sandra M Sims
  • Janice M Friis
  • Joe Palandra
  • Eric M Shobe
  • Jana L Jensen
  • Donald P Smith
  • Wade J Adams
  • John J Biermacher
  • John D Hosley
  • Jeffrey S Day

Detail Information

Publications3

  1. ncbi Solubility and permeability measurement and applications in drug discovery
    Philip S Burton
    ADMETRX Inc, 4717 Campus Drive, Suite 600, Kalamazoo, MI 49008, USA
    Comb Chem High Throughput Screen 13:101-11. 2010
    ..In this overview, we will discuss solubility and permeability experimental and computational methods separately and then interrelate them in physiologically relevant models for predicting in vivo performance...
  2. ncbi Predicting oral absorption of drugs: a case study with a novel class of antimicrobial agents
    Allen R Hilgers
    Drug Absorption and Transport, Global Pharmaceutical Sciences, Pharmacia, Kalamazoo, 49007, USA
    Pharm Res 20:1149-55. 2003
    ..In the case of compounds with poor aqueous solubility, additional factors may have to be considered such as solubility in the intestinal lumen...
  3. ncbi Predicting drug absorption: how nature made it a difficult problem
    Philip S Burton
    Drug Absorption and Transport, Pharmacia, Kalamazoo, Michigan 49007, USA
    J Pharmacol Exp Ther 303:889-95. 2002
    ..This article will explore the influence of these different variables on drug absorption and the implications with regards to attempting to develop predictive drug absorption algorithms...