J M Bujnicki

Summary

Publications

  1. Bujnicki J. Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases. Acta Microbiol Pol. 2000;49:19-29 pubmed
    ....
  2. Bujnicki J. Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases. FASEB J. 2000;14:2365-8 pubmed
    ....
  3. Bujnicki J, Rychlewski L. Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases. Protein Sci. 2001;10:656-60 pubmed
    ....
  4. Bujnicki J, Rychlewski L. Grouping together highly diverged PD-(D/E)XK nucleases and identification of novel superfamily members using structure-guided alignment of sequence profiles. J Mol Microbiol Biotechnol. 2001;3:69-72 pubmed
    ..The first superfamily-wide comparative analysis, not limited to nucleases of known structure, will guide cloning and characterization of novel enzymes and planning new experiments to better understand those already studied. ..
  5. Bujnicki J, Rychlewski L. Prediction of a novel RNA 2'-O-ribose methyltransferase subfamily encoded by the Escherichia coli YgdE open reading frame and its orthologs. Acta Microbiol Pol. 2000;49:253-60 pubmed
    ..The N-terminal region of YgdE, which has no counterpart in RrmJ, is predicted to form an independent domain, possibly involved in target recognition. ..
  6. Bujnicki J, Feder M, Radlinska M, Rychlewski L. mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships. BMC Bioinformatics. 2001;2:2 pubmed
    ....
  7. Bujnicki J, Blumenthal R, Rychlewski L. Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus. J Mol Microbiol Biotechnol. 2002;4:93-9 pubmed
    ....
  8. Bujnicki J, Rychlewski L. Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases. Acta Microbiol Pol. 2001;50:7-17 pubmed
    ..Comparison of a three-dimensional model of the Agr family member with a recently solved structure of reovirus mRNA capping MTase suggests that the mechanism of guanine-N7 methylation in rRNA and mRNA may be different...

Locale

Detail Information

Publications8

  1. Bujnicki J. Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases. Acta Microbiol Pol. 2000;49:19-29 pubmed
    ....
  2. Bujnicki J. Phylogenomic analysis of 16S rRNA:(guanine-N2) methyltransferases suggests new family members and reveals highly conserved motifs and a domain structure similar to other nucleic acid amino-methyltransferases. FASEB J. 2000;14:2365-8 pubmed
    ....
  3. Bujnicki J, Rychlewski L. Unusual evolutionary history of the tRNA splicing endonuclease EndA: relationship to the LAGLIDADG and PD-(D/E)XK deoxyribonucleases. Protein Sci. 2001;10:656-60 pubmed
    ....
  4. Bujnicki J, Rychlewski L. Grouping together highly diverged PD-(D/E)XK nucleases and identification of novel superfamily members using structure-guided alignment of sequence profiles. J Mol Microbiol Biotechnol. 2001;3:69-72 pubmed
    ..The first superfamily-wide comparative analysis, not limited to nucleases of known structure, will guide cloning and characterization of novel enzymes and planning new experiments to better understand those already studied. ..
  5. Bujnicki J, Rychlewski L. Prediction of a novel RNA 2'-O-ribose methyltransferase subfamily encoded by the Escherichia coli YgdE open reading frame and its orthologs. Acta Microbiol Pol. 2000;49:253-60 pubmed
    ..The N-terminal region of YgdE, which has no counterpart in RrmJ, is predicted to form an independent domain, possibly involved in target recognition. ..
  6. Bujnicki J, Feder M, Radlinska M, Rychlewski L. mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships. BMC Bioinformatics. 2001;2:2 pubmed
    ....
  7. Bujnicki J, Blumenthal R, Rychlewski L. Sequence analysis and structure prediction of 23S rRNA:m1G methyltransferases reveals a conserved core augmented with a putative Zn-binding domain in the N-terminus and family-specific elaborations in the C-terminus. J Mol Microbiol Biotechnol. 2002;4:93-9 pubmed
    ....
  8. Bujnicki J, Rychlewski L. Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases. Acta Microbiol Pol. 2001;50:7-17 pubmed
    ..Comparison of a three-dimensional model of the Agr family member with a recently solved structure of reovirus mRNA capping MTase suggests that the mechanism of guanine-N7 methylation in rRNA and mRNA may be different...