Jean Frederic Brun

Summary

Publications

  1. ncbi request reprint The paradox of hematocrit in exercise physiology: which is the "normal" range from an hemorheologist's viewpoint?
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 22:287-303. 2000
  2. ncbi request reprint Exercise hemorheology as a three acts play with metabolic actors: is it of clinical relevance?
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation de Anomalies du Métabolisme Musculaire, CHU Lapeyronie, Montipellier, France
    Clin Hemorheol Microcirc 26:155-74. 2002
  3. ncbi request reprint Postprandial reactive hypoglycemia
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires CERAMM, Lapeyronie Hospital Montpellier, France
    Diabetes Metab 26:337-51. 2000
  4. ncbi request reprint Exercise hypoglycemia in nondiabetic subjects
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires, Lapeyronie Hospital Montpellier, France
    Diabetes Metab 27:92-106. 2001
  5. ncbi request reprint Postexercise red cell aggregation is negatively correlated with blood lactate rate of disappearance
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 26:231-9. 2002
  6. doi request reprint Interrelationships among body composition, blood rheology and exercise performance
    Jean Frederic Brun
    U1046, INSERM, Universite de Montpellier 1, Université de Montpellier 2, Montpellier, France
    Clin Hemorheol Microcirc 49:183-97. 2011
  7. ncbi request reprint Substrate oxidation during exercise at moderate and hard intensity in middle-aged and young athletes vs sedentary men
    Jerome Manetta
    Metabolic Unit, Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires CERAMM, 34295 Montpellier Cedex 5, France
    Metabolism 54:1411-9. 2005
  8. doi request reprint Body composition and exercise performance as determinants of blood rheology in middle-aged patients exhibiting the metabolic syndrome
    Jean Frederic Brun
    U1046, INSERM, Universite de Montpellier 1, Université de Montpellier 2, Montpellier, France
    Clin Hemorheol Microcirc 49:215-23. 2011
  9. doi request reprint Effects of exercise training on blood rheology: a meta-analysis
    Ahmed Jérôme Romain
    Laboratoire Epsylon EA4556, Dynamique des capacités humaines et des conduites de santé Montpellier, Montpellier, France
    Clin Hemorheol Microcirc 49:199-205. 2011
  10. ncbi request reprint Type 2 diabetics with higher plasma viscosity exhibit a higher blood pressure
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 30:365-72. 2004

Collaborators

Detail Information

Publications22

  1. ncbi request reprint The paradox of hematocrit in exercise physiology: which is the "normal" range from an hemorheologist's viewpoint?
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 22:287-303. 2000
    ..6%) were frequently overtrained and/or iron-deficient, and their blood viscosity (and red cell disaggregability) tended to be increased...
  2. ncbi request reprint Exercise hemorheology as a three acts play with metabolic actors: is it of clinical relevance?
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation de Anomalies du Métabolisme Musculaire, CHU Lapeyronie, Montipellier, France
    Clin Hemorheol Microcirc 26:155-74. 2002
    ..Hemorheological measurements require to be studied, at least as sensitive markers of training, and possibly as "true" risk factors highly sensitive to exercise intensification...
  3. ncbi request reprint Postprandial reactive hypoglycemia
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires CERAMM, Lapeyronie Hospital Montpellier, France
    Diabetes Metab 26:337-51. 2000
    ..PRH is influenced by patient's alimentary habits (high carbohydrate-low fat diet, alcohol intake). Thus, diet remains the main treatment, although alpha-glucosidase inhibitors and some other drugs may be helpful...
  4. ncbi request reprint Exercise hypoglycemia in nondiabetic subjects
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires, Lapeyronie Hospital Montpellier, France
    Diabetes Metab 27:92-106. 2001
    ..Exercise hypoglycemia is a cause of fatigue or exercise cessation, but also impairs thermoregulatory adaptation and is assumed to fragilize muscles and tendons for traumatic events...
  5. ncbi request reprint Postexercise red cell aggregation is negatively correlated with blood lactate rate of disappearance
    J F Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 26:231-9. 2002
    ....
  6. doi request reprint Interrelationships among body composition, blood rheology and exercise performance
    Jean Frederic Brun
    U1046, INSERM, Universite de Montpellier 1, Université de Montpellier 2, Montpellier, France
    Clin Hemorheol Microcirc 49:183-97. 2011
    ....
  7. ncbi request reprint Substrate oxidation during exercise at moderate and hard intensity in middle-aged and young athletes vs sedentary men
    Jerome Manetta
    Metabolic Unit, Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires CERAMM, 34295 Montpellier Cedex 5, France
    Metabolism 54:1411-9. 2005
    ..In view of these findings, we hypothesize that cycling training performed at a specific exercise intensity (ie, 15% above VT) may improve CHO mobilization and use in middle-aged men...
  8. doi request reprint Body composition and exercise performance as determinants of blood rheology in middle-aged patients exhibiting the metabolic syndrome
    Jean Frederic Brun
    U1046, INSERM, Universite de Montpellier 1, Université de Montpellier 2, Montpellier, France
    Clin Hemorheol Microcirc 49:215-23. 2011
    ....
  9. doi request reprint Effects of exercise training on blood rheology: a meta-analysis
    Ahmed Jérôme Romain
    Laboratoire Epsylon EA4556, Dynamique des capacités humaines et des conduites de santé Montpellier, Montpellier, France
    Clin Hemorheol Microcirc 49:199-205. 2011
    ..In addition, this heterogeneity leads to conclude that more studies are needed to further analyze these effects which are described by a low number of articles, which could explain some of the non-significant results...
  10. ncbi request reprint Type 2 diabetics with higher plasma viscosity exhibit a higher blood pressure
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 30:365-72. 2004
    ..Therefore, in NIDDM, higher plasma viscosity, regardless insulin resistance and adiposity, is strongly related to blood pressure...
  11. doi request reprint Blood rheology and body composition as determinants of exercise performance in female rugby players
    Jean Frederic Brun
    U1046, INSERM, Universite de Montpellier 1, Université de Montpellier 2, Montpellier, France
    Clin Hemorheol Microcirc 49:207-14. 2011
    ..In addition, parameters quantifying fatness even within such a physiological range are in this sample negatively related with exercise performance...
  12. ncbi request reprint Hemorheological aspects of the metabolic syndrome: markers of insulin resistance, obesity or hyperinsulinemia?
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 30:203-9. 2004
    ..Myrenne "M1" aggregation is rather a marker of hyperinsulinemia. Thus, the hemorheologic picture of the metabolic syndrome is far to be only a reflect of insulin resistance alone...
  13. ncbi request reprint Blood fluidity is related to the ability to oxidize lipids at exercise
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, Montpellier, France
    Clin Hemorheol Microcirc 30:339-43. 2004
    ....
  14. ncbi request reprint Evaluation of insulin sensitivity and glucose effectiveness during a standardized breakfast test: comparison with the minimal model analysis of an intravenous glucose tolerance test
    Ikram Aloulou
    Metabolic Unit, Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies du Métabolisme Musculaire CERAMM, CHU Lapeyronie, 34295 Montpellier Cedex 5, France
    Metabolism 55:676-90. 2006
    ..185(G60- Gb) (Ip=insulin peak; Gp=glucose peak; Ia=insulin area; Ga=glucose area; G60=glycemia at 60 minutes). The hyperglucidic SBT can provide accurate evaluations of SI and Sg, either by elaborated models or by simple empiric formulas...
  15. doi request reprint Both overall adiposity and abdominal adiposity increase blood viscosity by separate mechanisms
    Jean Frederic Brun
    Physiopathologie and Médecine Expérimentale du Coeur et des Muscles INSERM U1046, Unité d Explorations Métaboliques CERAMM, Service Central de Physiologie Clinique, Hopital Lapeyronie CHU Montpellier, France
    Clin Hemorheol Microcirc 48:257-63. 2011
    ..These data suggest that both overall adiposity and abdominal adiposity induce hyper viscosity, consistent with epidemiological studies linking the risk of CHD to abdominal adiposity and BMI...
  16. doi request reprint Hemorheological alterations related to training and overtraining
    Jean Frederic Brun
    Service Central de Physiologie Clinique, Unité d Exploration Métabolique, CHU Lapeyronie, Montpellier, France
    Biorheology 47:95-115. 2010
    ..Given the variety of modes of exercise and the wide heterogeneity of their effects on blood rheology in the short and long term, many investigations remain to be performed in this area of clinical hemorheology...
  17. ncbi request reprint Limited accuracy of surrogates of insulin resistance during puberty in obese and lean children at risk for altered glucoregulation
    Frédérique Brandou
    Equipe d Accueil 701, Physiologie des Interactions, Service Central de Physiologie Clinique, Centre Hospitalier Universitaire Lapeyronie, 34295 Montpellier, France
    J Clin Endocrinol Metab 90:761-7. 2005
    ..Because reference methods are rather expensive and invasive, additional studies of alternative techniques for evaluating SI are needed to allow accurate measurement of insulin resistance in children...
  18. ncbi request reprint Oxidative mechanisms at rest and during exercise
    Edouard Ghanassia
    INSERM, ERI 25, F 34000, Montpellier, France
    Clin Chim Acta 383:1-20. 2007
    ....
  19. pmc Assessment of single-dose benzodiazepines on insulin secretion, insulin sensitivity and glucose effectiveness in healthy volunteers: a double-blind, placebo-controlled, randomized cross-over trial [ISRCTN08745124]
    Hugues Chevassus
    Clinical Investigation Center, Saint Eloi University Hospital, Section of Clinical Pharmacology, Montpellier, France
    BMC Clin Pharmacol 4:3. 2004
    ..5 gkg-1) glucose tolerance test with minimal-model analysis...
  20. ncbi request reprint Fuel oxidation during exercise in middle-aged men: role of training and glucose disposal
    Jerome Manetta
    Service Central de Physiologie Clinique, Centre d Exploration et de Réadaptation des Anomalies Métaboliques et Musculaires CERAMM, CHU Lapeyronie, and Laboratoire de Biochimie B, CHU Saint Eloi, 34295 Montpellier Cedex 5, France
    Med Sci Sports Exerc 34:423-9. 2002
    ..We also investigated whether a relationship between CHO utilization and glucose disposal exists...
  21. doi request reprint Blood rheology and body composition as determinants of exercise performance in male soccer players
    Emmanuelle Varlet-Marie
    Laboratoire Performance Santé Altitude, Département Sciences et Techniques des Activités Physiques et Sportives, Universite de Perpignan Via Domitia, Font Romeu, France
    Clin Hemorheol Microcirc 49:225-30. 2011
    ..These data are consistent with previous reports about soccer players but caution is needed to extrapolate to other sports...
  22. pmc Grape polyphenols prevent fructose-induced oxidative stress and insulin resistance in first-degree relatives of type 2 diabetic patients
    Marie Hokayem
    Inserm U1046, Physiologie and Médecine Expérimentale du Cœur et des Muscles, Montpellier, France
    Diabetes Care 36:1454-61. 2013
    ....