Mark A Brown

Summary

Publications

  1. pmc Hsp90--from signal transduction to cell transformation
    Mark A Brown
    Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, The University of Texas at Austin, 1 University Station A5000, Austin, TX 78712, USA
    Biochem Biophys Res Commun 363:241-6. 2007
  2. pmc Epigenetic aberrations and cancer
    Miryam Ducasse
    Institute for Biomedical Research Georg Speyer Haus, 60596 Frankfurt, Germany
    Mol Cancer 5:60. 2006
  3. pmc Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex
    Mark A Brown
    Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
    Mol Cancer 5:26. 2006
  4. pmc Circadian rhythm sleep disorder, free-running type in a sighted male with severe depression, anxiety, and agoraphobia
    Mark A Brown
    Department of Psychiatry, University of Arizona, Tucson, AZ, USA
    J Clin Sleep Med 7:93-4. 2011
  5. ncbi request reprint Identification of catalytically important amino acids in human ceruloplasmin by site-directed mutagenesis
    Mark A Brown
    Department of Biochemistry and Molecular Biology, and the UBC Centre for Blood Research, Faculty of Medicine, University of British Columbia, 2146 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
    FEBS Lett 520:8-12. 2002

Detail Information

Publications5

  1. pmc Hsp90--from signal transduction to cell transformation
    Mark A Brown
    Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, The University of Texas at Austin, 1 University Station A5000, Austin, TX 78712, USA
    Biochem Biophys Res Commun 363:241-6. 2007
    ..Here, we review the contemporary body of knowledge regarding the biochemical mechanisms of Hsp90 and update the most current paradigms defining its involvement in both normal and pathological cell physiology...
  2. pmc Epigenetic aberrations and cancer
    Miryam Ducasse
    Institute for Biomedical Research Georg Speyer Haus, 60596 Frankfurt, Germany
    Mol Cancer 5:60. 2006
    ..The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms. Here, we review recent findings regarding chromatin modifications and their relevance to cancer...
  3. pmc Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex
    Mark A Brown
    Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
    Mol Cancer 5:26. 2006
    ..Methylation of lysine residues is commonly catalyzed by a family of proteins that contain the SET domain. Here, we report the identification and characterization of the SET domain-containing protein, Smyd2...
  4. pmc Circadian rhythm sleep disorder, free-running type in a sighted male with severe depression, anxiety, and agoraphobia
    Mark A Brown
    Department of Psychiatry, University of Arizona, Tucson, AZ, USA
    J Clin Sleep Med 7:93-4. 2011
    ..The agoraphobia may have exacerbated the CRSD, FRT. Entrainment and stabilization of his circadian rhythm was accomplished after treatment that included melatonin, light therapy, and increased sleep structure...
  5. ncbi request reprint Identification of catalytically important amino acids in human ceruloplasmin by site-directed mutagenesis
    Mark A Brown
    Department of Biochemistry and Molecular Biology, and the UBC Centre for Blood Research, Faculty of Medicine, University of British Columbia, 2146 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
    FEBS Lett 520:8-12. 2002
    ..For the L329M variant, both activities were identical to those of wild-type ceruloplasmin...