Diane Brisson

Summary

Publications

  1. pmc The lipid accumulation product for the early prediction of gestational insulin resistance and glucose dysregulation
    Diane Brisson
    Department of Medicine, Universite de Montre al, ECOGENE 21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada
    J Womens Health (Larchmt) 22:362-7. 2013
  2. pmc The "hypertriglyceridemic waist" phenotype and glucose intolerance in pregnancy
    Diane Brisson
    Department of Medicine, Universite de Montreal, Montreal, Canada
    CMAJ 182:E722-5. 2010
  3. pmc IGF2 DNA methylation is a modulator of newborn's fetal growth and development
    Julie St-Pierre
    Department of Pediatrics, Chicoutimi Hospital, Chicoutimi, QC, Canada
    Epigenetics 7:1125-32. 2012
  4. doi request reprint Etiology and risk of lactescent plasma and severe hypertriglyceridemia
    Karine Tremblay
    Department of Medicine, Université de Montréal and ECOGENE 21 Clinical Research Center, Chicoutimi Hospital, Pavillon des Augustines 5th Floor, 225, St Vallier Street, Chicoutimi QC, Canada, G7H 7P2
    J Clin Lipidol 5:37-44. 2011
  5. doi request reprint Contribution of adiponectin to the cardiometabolic risk of postmenopausal women with loss-of-function lipoprotein lipase gene mutations
    Yacine Loucif
    Department of Medicine, Universite de Montreal, Montreal, ECOGENE 21 Clinical Research Center, Chicoutimi Hospital, Chicoutimi, Quebec, Canada
    Menopause 18:558-62. 2011
  6. ncbi request reprint Relation of the "hypertriglyceridemic waist" phenotype to earlier manifestations of coronary artery disease in patients with glucose intolerance and type 2 diabetes mellitus
    Julie St-Pierre
    Department of Medicine, Universite de Montreal, University of Montreal Community Genomic Medicine Center and Lipid Clinic, Chicoutimi Hospital, Chicoutimi, Quebec, Canada
    Am J Cardiol 99:369-73. 2007
  7. pmc Association between salivary pH and metabolic syndrome in women: a cross-sectional study
    Monique Tremblay
    Universite de Montreal, Department of Medicine, ECOGENE 21 Clinical Research Center Chicoutimi Hospital, 305 St Vallier Street, Chicoutimi Québec, Saguenay, Canada
    BMC Oral Health 12:40. 2012
  8. ncbi request reprint Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population
    James C Engert
    McGill University Health Centre, Montreal, Quebec, Canada
    Eur J Hum Genet 16:105-14. 2008
  9. pmc Placental adiponectin gene DNA methylation levels are associated with mothers' blood glucose concentration
    Luigi Bouchard
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Diabetes 61:1272-80. 2012
  10. pmc Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy
    Luigi Bouchard
    Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    Diabetes Care 33:2436-41. 2010

Collaborators

Detail Information

Publications23

  1. pmc The lipid accumulation product for the early prediction of gestational insulin resistance and glucose dysregulation
    Diane Brisson
    Department of Medicine, Universite de Montre al, ECOGENE 21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada
    J Womens Health (Larchmt) 22:362-7. 2013
    ..Among women without a history of gestational diabetes, we tested the association between the lipid accumulation product (LAP) obtained in early pregnancy and glucose dysregulation or insulin resistance in the second trimester...
  2. pmc The "hypertriglyceridemic waist" phenotype and glucose intolerance in pregnancy
    Diane Brisson
    Department of Medicine, Universite de Montreal, Montreal, Canada
    CMAJ 182:E722-5. 2010
    ..Our study aimed to assess the association between the hyper-triglyceridemic-waist phenotype in early pregnancy and glucose intolerance in later pregnancy...
  3. pmc IGF2 DNA methylation is a modulator of newborn's fetal growth and development
    Julie St-Pierre
    Department of Pediatrics, Chicoutimi Hospital, Chicoutimi, QC, Canada
    Epigenetics 7:1125-32. 2012
    ..IGF2/H19 DNA methylation could represent a cornerstone in linking birth weight and fetal metabolic programming of late onset obesity...
  4. doi request reprint Etiology and risk of lactescent plasma and severe hypertriglyceridemia
    Karine Tremblay
    Department of Medicine, Université de Montréal and ECOGENE 21 Clinical Research Center, Chicoutimi Hospital, Pavillon des Augustines 5th Floor, 225, St Vallier Street, Chicoutimi QC, Canada, G7H 7P2
    J Clin Lipidol 5:37-44. 2011
    ..Plasma lactescence is a clinical sign of severe hypertriglyceridemia (hyperTG; TG >10 mmol/L), which is likely to be observed more frequently in the next decades because of the growing prevalence of obesity and diabetes worldwide...
  5. doi request reprint Contribution of adiponectin to the cardiometabolic risk of postmenopausal women with loss-of-function lipoprotein lipase gene mutations
    Yacine Loucif
    Department of Medicine, Universite de Montreal, Montreal, ECOGENE 21 Clinical Research Center, Chicoutimi Hospital, Chicoutimi, Quebec, Canada
    Menopause 18:558-62. 2011
    ..The objective of this study was to evaluate the contribution of plasma adiponectin to the cardiometabolic status of women with loss-of-function LPL gene variants (LPLD)...
  6. ncbi request reprint Relation of the "hypertriglyceridemic waist" phenotype to earlier manifestations of coronary artery disease in patients with glucose intolerance and type 2 diabetes mellitus
    Julie St-Pierre
    Department of Medicine, Universite de Montreal, University of Montreal Community Genomic Medicine Center and Lipid Clinic, Chicoutimi Hospital, Chicoutimi, Quebec, Canada
    Am J Cardiol 99:369-73. 2007
    ....
  7. pmc Association between salivary pH and metabolic syndrome in women: a cross-sectional study
    Monique Tremblay
    Universite de Montreal, Department of Medicine, ECOGENE 21 Clinical Research Center Chicoutimi Hospital, 305 St Vallier Street, Chicoutimi Québec, Saguenay, Canada
    BMC Oral Health 12:40. 2012
    ..The objective of this study was therefore to document the association between salivary pH and MetS expression in women according to the menopausal status...
  8. ncbi request reprint Identification of a chromosome 8p locus for early-onset coronary heart disease in a French Canadian population
    James C Engert
    McGill University Health Centre, Montreal, Quebec, Canada
    Eur J Hum Genet 16:105-14. 2008
    ..In conclusion, a genome-wide scan and additional fine mapping provide evidence for a locus on chromosome 8 that contributes to CHD in a French Canadian population...
  9. pmc Placental adiponectin gene DNA methylation levels are associated with mothers' blood glucose concentration
    Luigi Bouchard
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Diabetes 61:1272-80. 2012
    ..Because adiponectin is suspected to have insulin-sensitizing proprieties, these epigenetic adaptations have the potential to induce sustained glucose metabolism changes in the mother and offspring later in life...
  10. pmc Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy
    Luigi Bouchard
    Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    Diabetes Care 33:2436-41. 2010
    ..To verify whether the leptin gene epigenetic (DNA methylation) profile is altered in the offspring of mothers with gestational impaired glucose tolerance (IGT)...
  11. doi request reprint Comparison of the efficacy of fibrates on hypertriglyceridemic phenotypes with different genetic and clinical characteristics
    Diane Brisson
    Department of Medicine, Universite de Montreal, ECOGENE 21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada
    Pharmacogenet Genomics 20:742-7. 2010
    ..Hypertriglyceridemia is a frequent and heterogeneous clinical trait, which modulates the risk of disease. Fibrates constitute an effective class of triglyceride-lowering agents...
  12. ncbi request reprint Epigenetic dysregulation of the IGF system in placenta of newborns exposed to maternal impaired glucose tolerance
    Véronique Desgagné
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Epigenomics 6:193-207. 2014
    ....
  13. doi request reprint Medical resource use and costs associated with chylomicronemia
    Daniel Gaudet
    Ecogene 21 Clinical Research Center and Department of Medicine, Universite de Montreal, Montreal, Canada
    J Med Econ 16:657-66. 2013
    ..Objective: To assess medical resource use and costs associated with chylomicronemia...
  14. doi request reprint Association of common polymorphisms in the fractalkine receptor (CX3CR1) with obesity
    Dave Sirois-Gagnon
    Departement des Sciences Fondamentales, Universite du Quebec a Chicoutimi, Saguenay, Quebec, Canada
    Obesity (Silver Spring) 19:222-7. 2011
    ..029). This study suggests that CX3CR1, a biomarker of obesity in this sample, constitutes a potential target for further investigation of the role of inflammation in the expression of obesity-related phenotypes...
  15. doi request reprint Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients
    Andre C Carpentier
    Department of Medicine, Division of Endocrinology, Universite de Sherbrooke, Sherbrooke, Quebec, Canada J1H 5N4
    J Clin Endocrinol Metab 97:1635-44. 2012
    ....
  16. ncbi request reprint Effect of apolipoprotein E, peroxisome proliferator-activated receptor alpha and lipoprotein lipase gene mutations on the ability of fenofibrate to improve lipid profiles and reach clinical guideline targets among hypertriglyceridemic patients
    Diane Brisson
    Community Genomic Medicine Centre, University of Montreal, Chicoutimi Hospital, Quebec, Canada
    Pharmacogenetics 12:313-20. 2002
    ..This study suggests that frequent genetic variations in genes encoding proteins involved in TG-rich lipoprotein metabolism could modulate the response to fenofibrate treatment, as defined in clinical guidelines...
  17. pmc Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol
    Guillaume Pare
    McGill University and Genome Quebec Innovation Centre, Montreal, Canada
    Am J Hum Genet 80:673-82. 2007
    ..Using an independent validation sample of 806 individuals, we confirm the EDN1 association (P<.005), whereas the LCAT association was nonsignificant (P=.12)...
  18. ncbi request reprint Metabolic syndrome and oral markers of cardiometabolic risk
    Monique Tremblay
    Chicoutimi Hospital, Chicoutimi QC, Canada
    J Can Dent Assoc 77:b125. 2011
    ....
  19. pmc Salivary pH as a marker of plasma adiponectin concentrations in Women
    Monique Tremblay
    Department of Medicine, Universite de Montreal, ECOGENE 21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, QC, Canada
    Diabetol Metab Syndr 4:4. 2012
    ..abstract:..
  20. ncbi request reprint Low plasma adiponectin exacerbates the risk of premature coronary artery disease in familial hypercholesterolemia
    Tarek Bouhali
    Lipid Research Group and University of Montreal Community Genomic Medicine Center, Universite de Montreal, Chicoutimi Hospital, 305 St Vallier, Chicoutimi, Quebec G7H 5H6, Canada
    Atherosclerosis 196:262-9. 2008
    ..73, confidence interval 95%: [1.19-2.53]; p=0.004). These results suggest that low plasma adiponectin is associated with an increased risk of premature CAD over and above the already exaggerated risk seen in FH patients...
  21. ncbi request reprint Prevalence of lifestyle risk factors in myotonic dystrophy type 1
    Cynthia Gagnon
    Faculty of Medicine and Health Sciences, Universite de Sherbrooke, Groupe de recherche interdisciplinaire sur les maladies neuromusculaires GRIMN, Neuromuscular Clinic, Centre de santé et de services sociaux de Jonquière, Quebec, Canada
    Can J Neurol Sci 40:42-7. 2013
    ..The objectives are: 1) To determine the prevalence of risk factors among individuals with DM1; 2) To compare the prevalence among classic and mild phenotypes...
  22. ncbi request reprint Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency
    Daniel Gaudet
    Department of Medicine, Universite de Montreal, ECOGENE 21 Clinical Research Center, Chicoutimi Hospital, Canada
    Atheroscler Suppl 11:55-60. 2010
    ..The clinical development program of alipogene tiparvovec includes observational studies as well as phase I/II and II/III clinical trials. Pooled data are collected on safety and efficacy issues, including the incidence of pancreatitis...
  23. doi request reprint On-site management of investigational products and drug delivery systems in conformity with Good Clinical Practices (GCPs)
    Julie Méthot
    Department of Medicine, Université de Montréal and ECOGENE 21 Clinical Trial Center, Chicoutimi Hospital, Chicoutimi, QC, Canada
    Clin Trials 9:265-71. 2012
    ....