Research Topics
Species | Paulo Cesar Bastos VieiraSummaryCountry: Brazil Publications
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Detail Information
Publications
Sepsis: from bench to bedsideEliezer Silva
Research Division, Heart Institute InCor, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
Clinics (Sao Paulo) 63:109-20. 2008..In this review, we address the research efforts that have been targeting risk factor identification, including genetics, pathophysiological mechanisms and strategies to recognize and treat these patients as early as possible...
Prowess-shock trial: a protocol overview and perspectivesEliezer Silva
Intensive Care Unit, Hospital Israelita Albert Einstein, Universidade de Sao Paulo, Sao Paulo, Brazil
Shock 34:48-53. 2010....
Do established prognostic factors explain the different mortality rates in ICU septic patients around the world?E Silva
Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Minerva Anestesiol 78:1215-25. 2012..The aim of this paper was to clarify if previously established prognostic factors explain the different mortality rates observed in ICU septic patients around the world...
Automatic versus manual pressure support reduction in the weaning of post-operative patients: a randomised controlled trialCorinne Taniguchi
Adult ICU Albert Einstein Hospital, Brazil
Crit Care 13:R6. 2009..We hypothesised that MRV is as effective as manual weaning in post-operative ICU patients...
Effects of volume resuscitation on splanchnic perfusion in canine model of severe sepsis induced by live Escherichia coli infusionClaudio Esteves Lagoa
Division of Applied Physiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
Crit Care 8:R221-8. 2004..We conducted the present study to investigate whether early large-volume crystalloid infusion can restore gut mucosal blood flow and mesenteric oxygen metabolism in severe sepsis...
Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registryRichard Beale
Division of Asthma, King s College London, Guy s, Campus, Great Maze Pond, London SE1 9RT, UK
Crit Care 14:R102. 2010....
Brazilian Sepsis Epidemiological Study (BASES study)Eliezer Silva
Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Crit Care 8:R251-60. 2004..This study was designed to verify the actual incidence density and outcome of sepsis in Brazilian ICUs. We also assessed the association between the Consensus Conference criteria and outcome..
Surviving sepsis campaign: a project to change sepsis trajectoryEliezer Silva
Department of Intensive Care, Albert Einstein Hospital and Discipline of Applied Physiology, Heart Institute, University of Sao Paulo, Sao Paulo, Brazil
Endocr Metab Immune Disord Drug Targets 6:217-22. 2006..This paper highlights the recommendations and the strategies proposed by SSC to implement them in intensive care units...
Sustained gastric mucosal acidosis after hemorrhage in spite of rapid hemodynamic restoration with blood or hypertonic/hyperoncotic solutionLuiz Francisco Poli de Figueiredo
Research Division, Heart Institute InCor and LIM11, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil
J Invest Surg 18:257-64. 2005....
Low hematocrit impairs gastric mucosal CO2 removal during experimental severe normovolemic hemodilutionDaniel Perin
Research Division, Heart Institute, , , SP, Brazil
Clinics 61:445-52. 2006..However, a very low hematocrit induced gastric mucosal acidosis, suggesting that gastric mucosal CO2 monitoring may be useful during major surgery or following trauma...
HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injuryEliezer Silva
Intensive Care Unit, Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil
Intensive Care Med 33:1829-39. 2007..In the present study we evaluated gene expression and activation of major intracellular signaling pathways in peripheral blood neutrophils obtained from patients with sepsis-induced acute lung injury after culture with HMGB1 or LPS...
Fluid replacement with hypertonic or isotonic solutions guided by mixed venous oxygen saturation in experimental hypodynamic sepsisLuciana Rahal
Department of Surgery and LIM26, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
J Trauma 67:1205-12. 2009..Our hypothesis was that a hypertonic isoncotic solution would improve the benefits of crystalloids replacement guided by mixed venous oxygen saturation...
Pulse oximetry wave variation as a noninvasive tool to assess volume status in cardiac surgeryGlauco A Westphal
Intensive Care Unit, Centro Hospitalar Unimed Joinville, Joinville, SC, Brazil
Clinics (Sao Paulo) 64:337-43. 2009....
A randomized controlled trial comparing a computer-assisted insulin infusion protocol with a strict and a conventional protocol for glucose control in critically ill patientsAlexandre B Cavalcanti
Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo 05652 000, Brazil
J Crit Care 24:371-8. 2009..The objective of this study is to evaluate blood glucose (BG) control efficacy and safety of 3 insulin protocols in medical intensive care unit (MICU) patients...
A multicentre, prospective study to evaluate costs of septic patients in Brazilian intensive care unitsAna M C Sogayar
Hospital Israelita Albert Einstein, Sao Paulo, Brazil
Pharmacoeconomics 26:425-34. 2008..Data on sepsis costs are scarce in the literature, and in developing countries such as Brazil these data are largely unavailable...
Pathogenesis-oriented targets for adjunctive therapyOtelo Rigato
Immunology Laboratory, Division of Infectious Diseases, Universidade Federal de Sao Paulo, CEP 04039-032, Sao Paulo, SP, Brazil
Endocr Metab Immune Disord Drug Targets 6:193-200. 2006..In this paper we aim to review some aspects of the pathogenesis of sepsis, focusing on possible targets for adjunctive therapy. Published clinical trials and experimental data supporting such trials are commented on...
Variant IRAK-1 haplotype is associated with increased nuclear factor-kappaB activation and worse outcomes in sepsisJohn Arcaroli
Intensive Care Unit, Albert Einstein Hospital and Division of Applied Physiology, Heart Institute, University of Sao Paulo, Brazil
Am J Respir Crit Care Med 173:1335-41. 2006..There are two haplotypes for the IRAK-1 gene in Caucasians, with the variant haplotype consisting of five intron single-nucleotide polymorphisms (SNPs) and three exon SNPs...
The effects of low and high tidal volume and pentoxifylline on intestinal blood flow and leukocyte-endothelial interactions in mechanically ventilated ratsPriscila Aikawa
Department of Cardiopneumology, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
Respir Care 56:1942-9. 2011..We hypothesized that high V(T) and high PEEP induce mesenteric microcirculatory disturbances and that those disturbances would be attenuated by pentoxifylline, which is anti-inflammatory...
